Page last updated: 2024-09-04

pomalidomide and carfilzomib

pomalidomide has been researched along with carfilzomib in 52 studies

Compound Research Comparison

Studies
(pomalidomide)
Trials
(pomalidomide)
Recent Studies (post-2010)
(pomalidomide)
Studies
(carfilzomib)
Trials
(carfilzomib)
Recent Studies (post-2010) (carfilzomib)
623121552748121716

Protein Interaction Comparison

ProteinTaxonomypomalidomide (IC50)carfilzomib (IC50)
Proteasome subunit beta type-11Homo sapiens (human)0.0608
26S proteasome non-ATPase regulatory subunit 11Homo sapiens (human)0.0086
26S proteasome non-ATPase regulatory subunit 12Homo sapiens (human)0.0086
26S proteasome non-ATPase regulatory subunit 14Homo sapiens (human)0.0086
Proteasome subunit alpha type-7Homo sapiens (human)0.0608
26S proteasome non-ATPase regulatory subunit 3Homo sapiens (human)0.0086
26S proteasome regulatory subunit 6AHomo sapiens (human)0.0086
Proteasome subunit beta type-1Homo sapiens (human)0.5937
Proteasome subunit alpha type-1Homo sapiens (human)0.0608
Proteasome subunit alpha type-2Homo sapiens (human)0.0608
Proteasome subunit alpha type-3Homo sapiens (human)0.0608
Proteasome subunit alpha type-4Homo sapiens (human)0.0608
Proteasome subunit beta type-8Homo sapiens (human)0.0407
Proteasome subunit beta type-9Homo sapiens (human)0.7166
Proteasome subunit alpha type-5Homo sapiens (human)0.0608
Proteasome subunit beta type-4Homo sapiens (human)0.0608
Proteasome subunit beta type-6Homo sapiens (human)0.199
Proteasome subunit beta type-5Homo sapiens (human)0.0237
26S proteasome regulatory subunit 7Homo sapiens (human)0.0086
Proteasome subunit beta type-10Homo sapiens (human)0.1339
26S proteasome regulatory subunit 6BHomo sapiens (human)0.0086
26S proteasome non-ATPase regulatory subunit 8Homo sapiens (human)0.0086
Proteasome subunit beta type-3Homo sapiens (human)0.0608
Proteasome subunit beta type-2Homo sapiens (human)0.7493
26S proteasome non-ATPase regulatory subunit 7Homo sapiens (human)0.0086
26S proteasome non-ATPase regulatory subunit 4Homo sapiens (human)0.0086
26S proteasome complex subunit SEM1Homo sapiens (human)0.0086
Proteasome subunit alpha type-6Homo sapiens (human)0.0608
26S proteasome regulatory subunit 4Homo sapiens (human)0.0086
26S proteasome regulatory subunit 8Homo sapiens (human)0.0086
26S proteasome regulatory subunit 10BHomo sapiens (human)0.0086
Glutathione S-transferase omega-1Homo sapiens (human)0.15
26S proteasome non-ATPase regulatory subunit 2Homo sapiens (human)0.0086
26S proteasome non-ATPase regulatory subunit 6Homo sapiens (human)0.0086
Proteasomal ubiquitin receptor ADRM1Homo sapiens (human)0.0086
Proteasome subunit alpha-type 8Homo sapiens (human)0.0608
Proteasome subunit beta type-7Homo sapiens (human)0.0578
26S proteasome non-ATPase regulatory subunit 1Homo sapiens (human)0.0086
26S proteasome non-ATPase regulatory subunit 13Homo sapiens (human)0.0086

Research

Studies (52)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (3.85)29.6817
2010's40 (76.92)24.3611
2020's10 (19.23)2.80

Authors

AuthorsStudies
Chen, W; Li, J; Liu, X; Shi, J; Zhang, Z; Zhao, L; Zhou, Y1
Jagannath, S1
Stewart, AK2
Schots, R1
Hata, H1
Niesvizky, R1
Arima, N; Kawada, H1
Mahindra, A; Saini, N1
Ahluwalia, R; Carson, KR; Cox, DP; Fiala, MA; Jaenicke, M; Moliske, CC; Stockerl-Goldstein, KE; Tomasson, MH; Trinkaus, KM; Vij, R; Wang, TF; Wildes, TM1
Lokhorst, HM; van de Donk, NW1
El-Amm, J; Tabbara, IA1
Mateos, MV; Ocio, EM; San Miguel, JF1
Orlowski, RZ1
Chen, SE; Highsmith, KN; Horowitz, S1
Gentili, S; Lonial, S1
Bories, C; Facon, T; Fouquet, G; Guidez, S; Herbaux, C; Javed, S; Leleu, X; Renaud, L1
Kuroda, J1
Anderson, KC; Dimopoulos, MA; Moreau, P; Richardson, PG1
Lonial, S; Usmani, SZ1
Colson, K1
Moreau, P; Touzeau, C1
Anderson, KC1
Dimopoulos, MA; Palumbo, A; San-Miguel, J; Siegel, D; Sonneveld, P1
Boise, LH; Kaufman, J; Lonial, S1
Abonour, R; Bensinger, WI; Cohen, AD; Durie, BG; Gasparetto, C; Gomes, CL; Kaufman, JL; Lentzsch, S; Orlowski, RZ; Pascucci, N; Shah, JJ; Smith, DD; Stadtmauer, EA; Vogl, DT1
Ito, S1
Bolomsky, A; Ludwig, H; Schlangen, K; Schreiner, W; Zojer, N1
Rochau, U; Siebert, U; Weger, R; Willenbacher, E; Willenbacher, W1
Jung, CK; Jung, Y; Kang, SW; Kim, BG; Kim, TH; Lee, SE; Lim, JY; Min, CK; Park, E; Park, J; Won, KA1
Biran, N; Duma, N; Richter, J; Siegel, D; Vesole, DH1
Broijl, A; Sonneveld, P1
Fan, L; Hu, C; Ma, X; Ran, X; Yu, H; Zou, Y1
Dimopoulos, MA; Gavriatopoulou, M; Kastritis, E; Terpos, E1
Abudayyeh, A; Doshi, M; Edeani, A; Glezerman, IG; Jhaveri, KD; Monga, D; Rosner, M; Wanchoo, R1
Boccadoro, M; Bonello, F; Larocca, A; Salvini, M1
Abouzaid, S; Chen, CC; Hussein, M; McGuiness, CB; Parikh, K; Purnomo, L; Wade, RL1
Abouzaid, S; Ailawadhi, S; Chandler, C; Guo, S; Mouro, J; Parikh, K; Pelligra, CG1
Costello, C; Mikhael, JR1
Sonneveld, P1
Belotti, A; Bertazzoni, P; Boccadoro, M; Bringhen, S; Cafro, AM; De Paoli, L; Fanin, R; Gaidano, G; Liberati, AM; Lombardo, A; Mina, R; Palumbo, A; Patriarca, F; Rossi, G; Sonneveld, P; Spada, S; Troia, R1
Borsi, E; Cavo, M; Mancuso, K; Martello, M; Pantani, L; Rocchi, S; Santacroce, B; Tacchetti, P; Terragna, C; Zamagni, E1
Tomlinson, R1
Chung, DJ; Diamond, B; Lesokhin, AM; Maclachlan, K; Ola Landgren, C1
Berenson, JR; Eades, B; Emamy-Sadr, M; Regidor, B; Spektor, TM; Swift, R; Tarhini, F1
Andriani, A; Annibali, O; Antolino, G; Cantonetti, M; Cimino, G; Coppetelli, U; De Rosa, L; De Stefano, V; di Toritto, TC; La Verde, G; Petrucci, MT; Piciocchi, A; Rizzo, M; Siniscalchi, A; Vozella, F; Za, T1
Asset, G; Baker, R; Capra, M; Dimopoulos, MA; Facon, T; Hajek, R; Kim, K; Koh, Y; Leleu, X; Macé, S; Martin, T; Martinez, G; Mikhael, J; Min, CK; Moreau, P; Oriol, A; Pour, L; Risse, ML; Špička, I; Suzuki, K; Yong, K1
Aslam, M; Atenafu, EG; Cherniawsky, H; Gul, E; Jimenez-Zepeda, VH; Kotb, R; LeBlanc, R; Louzada, ML; Masih-Khan, E; McCurdy, A; Reece, DE; Reiman, A; Sebag, M; Song, K; Stakiw, J; Venner, CP; White, D1
Berenson, JR; Eades, B; Eshaghian, S; Ghermezi, M; Lim, S; Martinez, D; Schwartz, G; Spektor, TM; Swift, RA; Vescio, R; Yashar, D1
Aslam, M; Gul, E; Jimenez-Zepeda, VH; Kardjadj, M; Kotb, R; LeBlanc, R; Louzada, M; Masih-Khan, E; McCurdy, A; Mian, H; Reece, D; Reiman, A; Sebag, M; Song, K; Stakiw, J; Venner, CP; White, D1
Berdeja, J; Cole, C; Derman, BA; Griffith, K; Jakubowiak, AJ; Jasielec, J; Kin, A; Major, A; Reece, D; Stefka, AT; Zonder, J1
Buadi, F; Dingli, D; Dispenzieri, A; Fonder, A; Gertz, MA; Go, R; Gonsalves, W; Hayman, S; Hobbs, M; Hwa, Y; Kapoor, P; Kourelis, T; Kumar, SK; Kyle, RA; Lacy, MQ; Leung, N; Lin, Y; Muchtar, E; Rajkumar, SV; Siddiqui, M; Vaxman, I; Warsame, R1

Reviews

25 review(s) available for pomalidomide and carfilzomib

ArticleYear
A review on the treatment of multiple myeloma with small molecular agents in the past five years.
    European journal of medicinal chemistry, 2022, Feb-05, Volume: 229

    Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; Combined Modality Therapy; Deubiquitinating Enzymes; Drug Development; Drug Resistance; Histone Deacetylases; Humans; Ikaros Transcription Factor; Immunomodulating Agents; Models, Molecular; Morpholines; Multiple Myeloma; Phthalimides; Piperidones; Proteasome Inhibitors; Treatment Outcome; Ubiquitin-Protein Ligases

2022
Novel therapies for relapsed myeloma.
    Hematology. American Society of Hematology. Education Program, 2009

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Boronic Acids; Bortezomib; Clinical Trials as Topic; Drug Administration Schedule; Drug Screening Assays, Antitumor; Drugs, Investigational; Heat-Shock Proteins; Histone Deacetylase Inhibitors; Humans; Immunologic Factors; Mice; Mice, Transgenic; Multiple Myeloma; Neoplasm Proteins; Nitrogen Mustard Compounds; Oligopeptides; Protease Inhibitors; Proteasome Inhibitors; Proto-Oncogene Proteins c-akt; Pyrazines; Salvage Therapy; Thalidomide

2009
[Development of novel agents for multiple myeloma; now and the future].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2011, Volume: 52, Issue:8

    Topics: Animals; Antibodies, Monoclonal, Humanized; Bendamustine Hydrochloride; Benzoquinones; Benzylamines; Clinical Trials as Topic; Cyclams; Drug Discovery; Drug Therapy, Combination; Heterocyclic Compounds; Humans; Hydroxamic Acids; Lactams, Macrocyclic; Molecular Targeted Therapy; Multiple Myeloma; Nitrogen Mustard Compounds; Oligopeptides; Thalidomide; Vorinostat

2011
Novel therapies in monoclonal gammopathies.
    Hematology (Amsterdam, Netherlands), 2012, Volume: 17 Suppl 1

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Humans; Immunologic Factors; Multiple Myeloma; Oligopeptides; Proteasome Inhibitors; Thalidomide

2012
[Update on treatment of multiple myeloma: including myeloma kidney and molecular targeting drugs].
    Nihon Jinzo Gakkai shi, 2012, Volume: 54, Issue:5

    Topics: Boronic Acids; Bortezomib; Drug Design; Humans; Immunologic Factors; Kidney Neoplasms; Lenalidomide; Molecular Targeted Therapy; Multiple Myeloma; Oligopeptides; Plasmacytoma; Pyrazines; Thalidomide

2012
Therapeutic strategies for the treatment of multiple myeloma.
    Discovery medicine, 2013, Volume: 15, Issue:83

    Topics: ADP-ribosyl Cyclase 1; Antineoplastic Agents; Boronic Acids; Bortezomib; Cytokines; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Homeostasis; Humans; Immune System; Immunotherapy; Lenalidomide; Multiple Myeloma; Oligopeptides; Prognosis; Protease Inhibitors; Pyrazines; Recurrence; Syndecan-1; Thalidomide

2013
Emerging therapies in multiple myeloma.
    American journal of clinical oncology, 2015, Volume: 38, Issue:3

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Histone Deacetylase Inhibitors; Humans; Immunologic Factors; Multiple Myeloma; Oligopeptides; Phosphorylcholine; Proteasome Inhibitors; Signal Transduction; Thalidomide

2015
Novel generation of agents with proven clinical activity in multiple myeloma.
    Seminars in oncology, 2013, Volume: 40, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Humans; Immunologic Factors; Lactones; Multiple Myeloma; Oligopeptides; Proteasome Inhibitors; Pyrroles; Recurrence; Thalidomide; Treatment Outcome

2013
Novel agents for multiple myeloma to overcome resistance in phase III clinical trials.
    Seminars in oncology, 2013, Volume: 40, Issue:5

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Benzamides; Clinical Trials, Phase III as Topic; Disease-Free Survival; Drug Resistance, Neoplasm; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Immunologic Factors; Indoles; Multiple Myeloma; Oligopeptides; Panobinostat; Phosphorylcholine; Piperidines; Proteasome Inhibitors; Pyridines; Remission Induction; Thalidomide; Thiazoles; Treatment Outcome; Vorinostat

2013
Carfilzomib and pomalidomide: recent advances in the treatment of multiple myeloma.
    Pharmacotherapy, 2014, Volume: 34, Issue:9

    Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Humans; Multiple Myeloma; Oligopeptides; Survival Rate; Thalidomide; Treatment Outcome

2014
Relapsed and refractory multiple myeloma: new therapeutic strategies.
    Hematology/oncology clinics of North America, 2014, Volume: 28, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Drug Resistance, Neoplasm; Humans; Multiple Myeloma; Neoplasm Recurrence, Local; Oligopeptides; Remission Induction; Thalidomide; Treatment Outcome

2014
Pomalidomide for multiple myeloma.
    Expert review of hematology, 2014, Volume: 7, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Boronic Acids; Bortezomib; Humans; Immunologic Factors; Lenalidomide; Multiple Myeloma; Neoplasm Recurrence, Local; Oligopeptides; Pyrazines; Thalidomide

2014
[Current status of clinical trials of novel agents for multiple myeloma].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2014, Volume: 55, Issue:10

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Drug Approval; Drug Discovery; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Lactones; Molecular Targeted Therapy; Multiple Myeloma; Oligopeptides; Pyrroles; Thalidomide; Vorinostat

2014
Current treatment landscape for relapsed and/or refractory multiple myeloma.
    Nature reviews. Clinical oncology, 2015, Volume: 12, Issue:1

    Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Boronic Acids; Bortezomib; Hematopoietic Stem Cell Transplantation; Humans; Immunoglobulins; Lenalidomide; Multiple Myeloma; Neoplasm Recurrence, Local; Oligopeptides; Peripheral Nervous System Diseases; Pyrazines; Thalidomide; Treatment Outcome

2015
Novel drug combinations for the management of relapsed/refractory multiple myeloma.
    Clinical lymphoma, myeloma & leukemia, 2014, Volume: 14 Suppl

    Topics: Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Disease Management; Disease Progression; Histone Deacetylase Inhibitors; Humans; Multiple Myeloma; Oligopeptides; Proteasome Inhibitors; Recurrence; Thalidomide

2014
Treatment-related symptom management in patients with multiple myeloma: a review.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2015, Volume: 23, Issue:5

    Topics: Antineoplastic Agents; Boronic Acids; Bortezomib; Drug-Related Side Effects and Adverse Reactions; Humans; Immunologic Factors; Immunomodulation; Lenalidomide; Multiple Myeloma; Oligopeptides; Peripheral Nervous System Diseases; Proteasome Inhibitors; Pyrazines; Quality of Life; Thalidomide

2015
Multiple myeloma: from front-line to relapsed therapies.
    American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting, 2015

    Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Drug Resistance, Neoplasm; Humans; Methotrexate; Multiple Myeloma; Neoplasm Recurrence, Local; Oligopeptides; Randomized Controlled Trials as Topic; Salvage Therapy; Stem Cell Transplantation; Thalidomide; Transplantation, Autologous; Vincristine

2015
Carfilzomib and pomalidomide in patients with relapsed and/or refractory multiple myeloma with baseline risk factors.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:11

    Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Clinical Trials as Topic; Humans; Multiple Myeloma; Neoplasm Recurrence, Local; Oligopeptides; Risk Factors; Thalidomide

2015
Treatment of relapsed and refractory multiple myeloma.
    Haematologica, 2016, Volume: 101, Issue:4

    Topics: Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Drug Resistance, Neoplasm; Humans; Immunologic Factors; Multiple Myeloma; Oligopeptides; Palliative Care; Plasma Cells; Precision Medicine; Proteasome Inhibitors; Recurrence; Thalidomide

2016
Carfilzomib/pomalidomide single-agent or in combination with other agents for the management of relapsed/refractory multiple myeloma: a meta-analysis of 37 trials.
    Oncotarget, 2017, Jun-13, Volume: 8, Issue:24

    Topics: Antineoplastic Combined Chemotherapy Protocols; Disease Management; Drug Resistance, Neoplasm; Humans; Multiple Myeloma; Neoplasm Recurrence, Local; Oligopeptides; Prospective Studies; Salvage Therapy; Thalidomide

2017
Current treatments for renal failure due to multiple myeloma.
    Expert opinion on pharmacotherapy, 2016, Volume: 17, Issue:16

    Topics: Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Bortezomib; Dexamethasone; Hematopoietic Stem Cell Transplantation; Humans; Lenalidomide; Multiple Myeloma; Oligopeptides; Renal Insufficiency; Thalidomide

2016
Renal Toxicities of Novel Agents Used for Treatment of Multiple Myeloma.
    Clinical journal of the American Society of Nephrology : CJASN, 2017, 01-06, Volume: 12, Issue:1

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bortezomib; Everolimus; Humans; Imidazoles; Immunologic Factors; Indoles; Kidney Diseases; Lenalidomide; Multiple Myeloma; Nivolumab; Oligopeptides; Oximes; Proteasome Inhibitors; Protein Kinase Inhibitors; Sulfonamides; Thalidomide; Vemurafenib

2017
Management of adverse events induced by next-generation immunomodulatory drug and proteasome inhibitors in multiple myeloma.
    Expert review of anticancer therapy, 2017, Volume: 17, Issue:1

    Topics: Antineoplastic Agents; Boron Compounds; Dose-Response Relationship, Drug; Glycine; Humans; Immunologic Factors; Multiple Myeloma; Oligopeptides; Proteasome Inhibitors; Survival Rate; Thalidomide

2017
Management of multiple myeloma in the relapsed/refractory patient.
    Hematology. American Society of Hematology. Education Program, 2017, 12-08, Volume: 2017, Issue:1

    Topics: Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Humans; Immunologic Factors; Multiple Myeloma; Oligopeptides; Proteasome Inhibitors; Recurrence; Thalidomide

2017
Maintenance therapy and need for cessation studies in multiple myeloma: Focus on the future.
    Best practice & research. Clinical haematology, 2020, Volume: 33, Issue:1

    Topics: Adaptive Clinical Trials as Topic; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Boron Compounds; Bortezomib; Disease-Free Survival; Drug Administration Schedule; Glycine; Hematopoietic Stem Cell Transplantation; Humans; Lenalidomide; Maintenance Chemotherapy; Multiple Myeloma; Neoplasm, Residual; Oligopeptides; Thalidomide; Transplantation, Autologous; Withholding Treatment

2020

Trials

5 trial(s) available for pomalidomide and carfilzomib

ArticleYear
Carfilzomib, pomalidomide, and dexamethasone for relapsed or refractory myeloma.
    Blood, 2015, Nov-12, Volume: 126, Issue:20

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dexamethasone; Female; Humans; Male; Maximum Tolerated Dose; Middle Aged; Multiple Myeloma; Oligopeptides; Pneumonia; Pulmonary Embolism; Recurrence; Thalidomide; Time Factors

2015
Once-weekly carfilzomib, pomalidomide, and low-dose dexamethasone for relapsed/refractory myeloma: a phase I/II study.
    Leukemia, 2018, Volume: 32, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cohort Studies; Dexamethasone; Follow-Up Studies; Humans; Multiple Myeloma; Oligopeptides; Prognosis; Survival Rate; Thalidomide

2018
Isatuximab, carfilzomib, and dexamethasone in relapsed multiple myeloma (IKEMA): a multicentre, open-label, randomised phase 3 trial.
    Lancet (London, England), 2021, 06-19, Volume: 397, Issue:10292

    Topics: Administration, Intravenous; Aged; Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Dexamethasone; Drug Therapy, Combination; Female; Humans; Immunologic Factors; Male; Middle Aged; Multiple Myeloma; Oligopeptides; Progression-Free Survival; Prospective Studies; Recurrence; Thalidomide

2021
A phase 2 trial of the efficacy and safety of elotuzumab in combination with pomalidomide, carfilzomib and dexamethasone for high-risk relapsed/refractory multiple myeloma.
    Leukemia & lymphoma, 2022, Volume: 63, Issue:4

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Dexamethasone; Humans; Multiple Myeloma; Neoplasm Recurrence, Local; Oligopeptides; Thalidomide

2022
Phase 1/2 study of carfilzomib, pomalidomide, and dexamethasone with and without daratumumab in relapsed multiple myeloma.
    Blood advances, 2023, 10-10, Volume: 7, Issue:19

    Topics: Antineoplastic Combined Chemotherapy Protocols; Dexamethasone; Humans; Multiple Myeloma

2023

Other Studies

22 other study(ies) available for pomalidomide and carfilzomib

ArticleYear
New drugs in multiple myeloma and the significance of autologous stem cell transplants.
    Clinical advances in hematology & oncology : H&O, 2009, Volume: 7, Issue:3

    Topics: Antineoplastic Agents; Humans; Multiple Myeloma; Oligopeptides; Stem Cell Transplantation; Thalidomide

2009
Recent advances in myeloma treatment.
    Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis, 2011, Volume: 44, Issue:2

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Boronic Acids; Bortezomib; Humans; Lenalidomide; Medical Oncology; Melphalan; Multiple Myeloma; Oligopeptides; Prednisone; Pyrazines; Quality of Life; Salvage Therapy; Stem Cell Transplantation; Thalidomide

2011
Novel therapeutics in multiple myeloma.
    Hematology (Amsterdam, Netherlands), 2012, Volume: 17 Suppl 1

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Immunologic Factors; Molecular Targeted Therapy; Multiple Myeloma; Oligopeptides; Proteasome Inhibitors; Thalidomide; Vorinostat

2012
The characteristics and outcomes of patients with multiple myeloma dual refractory or intolerant to bortezomib and lenalidomide in the era of carfilzomib and pomalidomide.
    Leukemia & lymphoma, 2014, Volume: 55, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Boronic Acids; Bortezomib; Drug Resistance, Neoplasm; Drug Tolerance; Female; Humans; Lenalidomide; Logistic Models; Male; Middle Aged; Multiple Myeloma; Multivariate Analysis; Oligopeptides; Outcome Assessment, Health Care; Prognosis; Pyrazines; Retrospective Studies; Risk Factors; Survival Analysis; Thalidomide

2014
New developments in the management and treatment of newly diagnosed and relapsed/refractory multiple myeloma patients.
    Expert opinion on pharmacotherapy, 2013, Volume: 14, Issue:12

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; Humans; Multiple Myeloma; Oligopeptides; Proteasome Inhibitors; Recurrence; Thalidomide

2013
Multiple myeloma: new uses for available agents, excitement for the future.
    Journal of the National Comprehensive Cancer Network : JNCCN, 2015, Volume: 13, Issue:5 Suppl

    Topics: Antineoplastic Agents; Humans; Multiple Myeloma; Oligopeptides; Practice Guidelines as Topic; Proteasome Inhibitors; Thalidomide

2015
How I treat high-risk myeloma.
    Blood, 2015, Sep-24, Volume: 126, Issue:13

    Topics: Aged; Antineoplastic Agents; Bortezomib; Female; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Lenalidomide; Multiple Myeloma; Oligopeptides; Proteasome Inhibitors; Thalidomide

2015
[Novel agents in multiple myeloma treatment].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2015, Volume: 56, Issue:10

    Topics: Antineoplastic Agents; Clinical Trials as Topic; Humans; Multiple Myeloma; Oligopeptides; Protein Kinase Inhibitors; Signal Transduction; Thalidomide

2015
Targeting of BMI-1 with PTC-209 shows potent anti-myeloma activity and impairs the tumour microenvironment.
    Journal of hematology & oncology, 2016, Mar-02, Volume: 9

    Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cells, Cultured; Dexamethasone; Drug Synergism; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds, 2-Ring; Human Umbilical Vein Endothelial Cells; Humans; Multiple Myeloma; Neovascularization, Physiologic; Oligopeptides; Osteogenesis; Polycomb Repressive Complex 1; Reverse Transcriptase Polymerase Chain Reaction; Thalidomide; Thiazoles; Tumor Microenvironment

2016
Real-World Use of 3rd Line Therapy for Multiple Myeloma in Austria: An Austrian Myeloma Registry (AMR) Analysis of the Therapeutic Landscape and Clinical Outcomes prior to the Use of Next Generation Myeloma Therapeutics.
    PloS one, 2016, Volume: 11, Issue:3

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Austria; Bortezomib; Female; Hematopoietic Stem Cell Transplantation; Humans; Lenalidomide; Male; Middle Aged; Multiple Myeloma; Oligopeptides; Prognosis; Recurrence; Registries; Retrospective Studies; Survival Analysis; Thalidomide; Transplantation, Autologous

2016
Oral proteasome inhibitor with strong preclinical efficacy in myeloma models.
    BMC cancer, 2016, Mar-24, Volume: 16

    Topics: Aged; Animals; Antineoplastic Agents; Apoptosis; Boron Compounds; Bortezomib; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Resistance, Neoplasm; Drug Synergism; Female; Glycine; Humans; Male; Mice; Middle Aged; Multiple Myeloma; Oligopeptides; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Thalidomide; Xenograft Model Antitumor Assays

2016
Safety and tolerability of pomalidomide-based regimens (pomalidomide-carfilzomib-dexamethasone with or without cyclophosphamide) in relapsed/refractory multiple myeloma and severe renal dysfunction: a case series.
    Hematological oncology, 2017, Volume: 35, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Dexamethasone; Female; Humans; Kidney Diseases; Middle Aged; Multiple Myeloma; Oligopeptides; Recurrence; Thalidomide

2017
Real-World Treatment Patterns, Time to Next Treatment, and Economic Outcomes in Relapsed or Refractory Multiple Myeloma Patients Treated with Pomalidomide or Carfilzomib.
    Journal of managed care & specialty pharmacy, 2017, Volume: 23, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Costs and Cost Analysis; Dexamethasone; Disease Progression; Female; Humans; Male; Middle Aged; Multiple Myeloma; Neoplasm Recurrence, Local; Oligopeptides; Retrospective Studies; Thalidomide

2017
Cost-effectiveness of Pomalidomide, Carfilzomib, and Daratumumab for the Treatment of Patients with Heavily Pretreated Relapsed-refractory Multiple Myeloma in the United States.
    Clinical therapeutics, 2017, Volume: 39, Issue:10

    Topics: Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Cost-Benefit Analysis; Dexamethasone; Disease-Free Survival; Drug Costs; Drug Resistance, Neoplasm; Humans; Models, Economic; Multiple Myeloma; Oligopeptides; Quality-Adjusted Life Years; Recurrence; Thalidomide; United States

2017
Therapy sequencing strategies in multiple myeloma: who, what and why?
    Future oncology (London, England), 2018, Volume: 14, Issue:2

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Boron Compounds; Glycine; Humans; Hydroxamic Acids; Indoles; Multiple Myeloma; Oligopeptides; Panobinostat; Thalidomide

2018
Treatment optimization for multiple myeloma: schedule-dependent synergistic cytotoxicity of pomalidomide and carfilzomib in
    Haematologica, 2018, Volume: 103, Issue:12

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Humans; Immunologic Factors; Multiple Myeloma; Oligopeptides; Proteasome Inhibitors; Thalidomide

2018
Multiple myeloma: Updated approach to management in 2018.
    Australian journal of general practice, 2018, Volume: 47, Issue:8

    Topics: Antibodies, Monoclonal; Antineoplastic Agents; beta 2-Microglobulin; Bortezomib; Disease Management; Humans; Hypercalcemia; Immunologic Factors; Lenalidomide; Multiple Myeloma; Oligopeptides; Pain; Prognosis; Renal Insufficiency; Serum Albumin; Thalidomide

2018
Frequent occurrence of hypophosphatemia among multiple myeloma patients treated with elotuzumab: a single clinic retrospective study.
    Annals of hematology, 2021, Volume: 100, Issue:4

    Topics: Aged; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bortezomib; Dexamethasone; Diphosphonates; Drug Interactions; Female; Humans; Hypophosphatemia; Lenalidomide; Male; Middle Aged; Multiple Myeloma; Oligopeptides; Retrospective Studies; Thalidomide

2021
Daratumumab in multiple myeloma: experience of the multiple myeloma GIMEMA Lazio group.
    Annals of hematology, 2021, Volume: 100, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Bortezomib; Clinical Trials, Phase II as Topic; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Hematopoietic Stem Cell Transplantation; Humans; Kaplan-Meier Estimate; Lenalidomide; Male; Middle Aged; Multicenter Studies as Topic; Multiple Myeloma; Myeloma Proteins; Oligopeptides; Progression-Free Survival; Thalidomide

2021
Retrospective study of treatment patterns and outcomes post-lenalidomide for multiple myeloma in Canada.
    European journal of haematology, 2021, Volume: 107, Issue:4

    Topics: Adult; Aged; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Boron Compounds; Bortezomib; Canada; Dexamethasone; Female; Glycine; Hematopoietic Stem Cell Transplantation; Humans; Lenalidomide; Maintenance Chemotherapy; Male; Middle Aged; Multiple Myeloma; Oligopeptides; Recurrence; Retrospective Studies; Salvage Therapy; Survival Analysis; Thalidomide; Transplantation, Autologous

2021
Sequential Use of Carfilzomib and Pomalidomide in Relapsed Multiple Myeloma: A Report from the Canadian Myeloma Research Group (CMRG) Database.
    Current oncology (Toronto, Ont.), 2022, 03-02, Volume: 29, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Canada; Dexamethasone; Humans; Multiple Myeloma; Neoplasm Recurrence, Local; Oligopeptides; Thalidomide

2022
Daratumumab, carfilzomib, and pomalidomide for the treatment of POEMS syndrome: The Mayo Clinic Experience.
    Blood cancer journal, 2023, 05-31, Volume: 13, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Humans; Multiple Myeloma; POEMS Syndrome; Thalidomide

2023