Page last updated: 2024-09-04

pomalidomide and azd 6244

pomalidomide has been researched along with azd 6244 in 2 studies

Compound Research Comparison

Studies (pomalidomide)	Trials (pomalidomide)	Recent Studies (post-2010) (pomalidomide)	Studies (azd 6244)	Trials (azd 6244)	Recent Studies (post-2010) (azd 6244)
623	121	552	477	80	423

Protein Interaction Comparison

Protein	Taxonomy	pomalidomide (IC50)	azd 6244 (IC50)
Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)		0.014
Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)		0.4845

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bian, J; Li, L; Li, Z; Meng, Y; Wang, J; Xu, P; Xu, X	1
Bjorklund, CC; Corchete, LA; Couto, S; Delgado, M; Díaz-Rodríguez, E; Fernández-Lázaro, D; Garayoa, M; García-Gómez, A; Gutiérrez, NC; López-Corral, L; Mateos, MV; Montero, JC; Ocio, EM; Paíno, T; Pandiella, A; San-Miguel, JF; San-Segundo, L; Wang, M	1

Other Studies

2 other study(ies) available for pomalidomide and azd 6244

Article	Year
Overview of the Development of Glutaminase Inhibitors: Achievements and Future Directions. Journal of medicinal chemistry, 2019, 02-14, Volume: 62, Issue:3 Topics: Animals; Benzophenanthridines; Benzoquinones; Catalytic Domain; Cell Line, Tumor; Drug Discovery; Enzyme Inhibitors; Glutaminase; Humans; Mice; Molecular Docking Simulation; Protein Binding; Sulfides; Thiadiazoles; Thiazolidinediones	2019
In vivo murine model of acquired resistance in myeloma reveals differential mechanisms for lenalidomide and pomalidomide in combination with dexamethasone. Leukemia, 2015, Volume: 29, Issue:3 Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents; Apoptosis; Benzimidazoles; Cell Line, Tumor; Dexamethasone; Disease Models, Animal; Drug Resistance, Neoplasm; Drug Therapy, Combination; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Neoplastic; Humans; Ikaros Transcription Factor; Lenalidomide; Mice; Multiple Myeloma; Neoplasm Transplantation; Nerve Tissue Proteins; Plasmacytoma; Signal Transduction; Thalidomide; Trans-Activators	2015

Article

Year

Overview of the Development of Glutaminase Inhibitors: Achievements and Future Directions.

Journal of medicinal chemistry, 2019, 02-14, Volume: 62, Issue:3

Topics: Animals; Benzophenanthridines; Benzoquinones; Catalytic Domain; Cell Line, Tumor; Drug Discovery; Enzyme Inhibitors; Glutaminase; Humans; Mice; Molecular Docking Simulation; Protein Binding; Sulfides; Thiadiazoles; Thiazolidinediones

2019

In vivo murine model of acquired resistance in myeloma reveals differential mechanisms for lenalidomide and pomalidomide in combination with dexamethasone.

Leukemia, 2015, Volume: 29, Issue:3

Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents; Apoptosis; Benzimidazoles; Cell Line, Tumor; Dexamethasone; Disease Models, Animal; Drug Resistance, Neoplasm; Drug Therapy, Combination; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Neoplastic; Humans; Ikaros Transcription Factor; Lenalidomide; Mice; Multiple Myeloma; Neoplasm Transplantation; Nerve Tissue Proteins; Plasmacytoma; Signal Transduction; Thalidomide; Trans-Activators

2015