Page last updated: 2024-09-03

polytrimethylene carbonate and sirolimus

polytrimethylene carbonate has been researched along with sirolimus in 2 studies

Compound Research Comparison

Studies (polytrimethylene carbonate)	Trials (polytrimethylene carbonate)	Recent Studies (post-2010) (polytrimethylene carbonate)	Studies (sirolimus)	Trials (sirolimus)	Recent Studies (post-2010) (sirolimus)
146	3	77	20,711	2,368	11,516

Protein Interaction Comparison

Protein	Taxonomy	sirolimus (IC50)
Bile salt export pump	Homo sapiens (human)	10
ATP-dependent translocase ABCB1	Homo sapiens (human)	1.25
Cytochrome P450 3A4	Homo sapiens (human)	2
Cytochrome P450 2C9	Homo sapiens (human)	2
Peptidyl-prolyl cis-trans isomerase FKBP1A	Mus musculus (house mouse)	0.001
Cytochrome P450 2C19	Homo sapiens (human)	4
Serine/threonine-protein kinase mTOR	Homo sapiens (human)	0.0897
Peptidyl-prolyl cis-trans isomerase FKBP1A	Homo sapiens (human)	0.0042
Regulatory-associated protein of mTOR	Homo sapiens (human)	0.225
Target of rapamycin complex subunit LST8	Homo sapiens (human)	0.225
Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)	1.9
Solute carrier organic anion transporter family member 1B1	Homo sapiens (human)	1.1

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Dobrzynski, P; Jarzabek, B; Jelonek, K; Kasperczyk, J; Li, S	1
Hong, D; Li, H; Liu, J; Tan, L; Xia, Y; Xu, K; Yang, K; Zhang, B; Zheng, F; Zhong, H	1

Other Studies

2 other study(ies) available for polytrimethylene carbonate and sirolimus

Article	Year
Controlled poly(l-lactide-co-trimethylene carbonate) delivery system of cyclosporine A and rapamycine--the effect of copolymer chain microstructure on drug release rate. International journal of pharmaceutics, 2011, Jul-29, Volume: 414, Issue:1-2 Topics: Cyclosporine; Delayed-Action Preparations; Dioxanes; Drug Carriers; Drug Compounding; Drug Delivery Systems; Immunosuppressive Agents; Polyesters; Polymers; Sirolimus; Solubility	2011
Enhanced efficacy of sirolimus-eluting bioabsorbable magnesium alloy stents in the prevention of restenosis. Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists, 2011, Volume: 18, Issue:3 Topics: Alloys; Angioplasty; Animals; Aorta, Abdominal; Aortic Diseases; Arterial Occlusive Diseases; Cardiovascular Agents; Cell Proliferation; Coated Materials, Biocompatible; Constriction, Pathologic; Dioxanes; Disease Models, Animal; Drug-Eluting Stents; Endothelial Cells; Hyperplasia; Lactic Acid; Magnesium; Male; Polyesters; Polymers; Prosthesis Design; Rabbits; Secondary Prevention; Sirolimus; Time Factors; Wound Healing	2011

Article

Year

Controlled poly(l-lactide-co-trimethylene carbonate) delivery system of cyclosporine A and rapamycine--the effect of copolymer chain microstructure on drug release rate.

International journal of pharmaceutics, 2011, Jul-29, Volume: 414, Issue:1-2

Topics: Cyclosporine; Delayed-Action Preparations; Dioxanes; Drug Carriers; Drug Compounding; Drug Delivery Systems; Immunosuppressive Agents; Polyesters; Polymers; Sirolimus; Solubility

2011

Enhanced efficacy of sirolimus-eluting bioabsorbable magnesium alloy stents in the prevention of restenosis.

Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists, 2011, Volume: 18, Issue:3

Topics: Alloys; Angioplasty; Animals; Aorta, Abdominal; Aortic Diseases; Arterial Occlusive Diseases; Cardiovascular Agents; Cell Proliferation; Coated Materials, Biocompatible; Constriction, Pathologic; Dioxanes; Disease Models, Animal; Drug-Eluting Stents; Endothelial Cells; Hyperplasia; Lactic Acid; Magnesium; Male; Polyesters; Polymers; Prosthesis Design; Rabbits; Secondary Prevention; Sirolimus; Time Factors; Wound Healing

2011