Compounds > podophyllotoxin
Page last updated: 2024-08-21

podophyllotoxin and triazoles

podophyllotoxin has been researched along with triazoles in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (30.77)29.6817
2010's7 (53.85)24.3611
2020's2 (15.38)2.80

Authors

AuthorsStudies
Cafici, L; Canonico, PL; Galli, U; Genazzani, AA; Imperio, D; Pagliai, F; Pirali, T; Sorba, G; Tron, GC1
Agrawal, SK; Bhat, BA; Kumar, HM; Qazi, GN; Reddy, PB; Saxena, AK1
Agrawal, SK; Kumar, HM; Paul, DV; Qazi, GN; Reddy, PB; Saxena, AK1
Agrawal, SK; Bhat, BA; Kumar, HM; Qazi, GN; Reddy, PB; Saxena, AK; Singh, S1
Chen, H; Chen, L; Li, T; Liu, D; Liu, J; Liu, Y; Lu, Y; Tang, X; Wang, X; Zhang, S; Zhao, M; Zuo, S1
Cao, D; Chen, J; Chen, L; Chen, T; Lai, H; Liang, X; Ma, L; Peng, A; Peng, F; Qiu, J; Ran, Y; Tang, J; Wang, G; Wang, J; Wei, Y; Xu, Q; Zhang, R1
Ding, ZT; Hu, JM; Jiang, ZH; Li, GT; Li, Y; Xu, FQ; Zhou, J; Zi, CT1
Ali, A; Goswami, A; Nayak, D; Sharma, PR; Vishwakarma, RA; Zilla, MK1
Błauż, A; Makal, A; Plażuk, D; Rychlik, B; Wieczorek, A1
Akunuri, R; Bhargava, SK; Bonam, SR; Kamal, A; Kumar, HMS; Naidu, VGM; Nayak, VL; Reddy, TS; Reddy, VG; Srihari, P1
Hou, W; Luo, Z; Su, L; Xu, H; Zhang, G1
Gavaji, B; Kankala, S; Nerella, S1
Duan, Y; Li, HM; Li, S; Li, YZ; Shen, Y; Tang, YJ; Zhang, Y; Zhao, W1

Other Studies

13 other study(ies) available for podophyllotoxin and triazoles

ArticleYear
Replacement of the lactone moiety on podophyllotoxin and steganacin analogues with a 1,5-disubstituted 1,2,3-triazole via ruthenium-catalyzed click chemistry.
    Bioorganic & medicinal chemistry, 2007, Nov-01, Volume: 15, Issue:21

    Topics: 4-Butyrolactone; Antineoplastic Agents; Catalysis; Cell Line, Tumor; Humans; Lactones; Lignans; Molecular Conformation; Podophyllotoxin; Ruthenium; Triazoles; Tubulin

2007
Studies on novel 4beta-[(4-substituted)-1,2,3-triazol-1-yl] podophyllotoxins as potential anticancer agents.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:10

    Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Design; Humans; Inhibitory Concentration 50; Podophyllotoxin; Stereoisomerism; Substrate Specificity; Triazoles

2008
Design, synthesis, and biological testing of 4beta-[(4-substituted)-1,2,3-triazol-1-yl]podophyllotoxin analogues as antitumor agents.
    Archiv der Pharmazie, 2008, Volume: 341, Issue:2

    Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Podophyllotoxin; Structure-Activity Relationship; Triazoles

2008
Synthesis and biological evaluation of 4beta-[(4-substituted)-1,2,3-triazol-1-yl]podophyllotoxins as potential anticancer agents.
    Chemistry & biodiversity, 2008, Volume: 5, Issue:9

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Podophyllotoxin; Structure-Activity Relationship; Triazoles

2008
Synthesis of 4β-triazole-podophyllotoxin derivatives by azide-alkyne cycloaddition and biological evaluation as potential antitumor agents.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:9

    Topics: Antineoplastic Agents; Azides; Cell Line, Tumor; Cyclization; Drug Screening Assays, Antitumor; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Podophyllotoxin; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Infrared; Triazoles

2011
Semi-synthesis and biological evaluation of 1,2,3-triazole-based podophyllotoxin congeners as potent antitumor agents inducing apoptosis in HepG2 cells.
    Archiv der Pharmazie, 2012, Volume: 345, Issue:12

    Topics: Antineoplastic Agents; Cell Cycle; Click Chemistry; Drug Screening Assays, Antitumor; Hep G2 Cells; Humans; Inhibitory Concentration 50; Molecular Docking Simulation; Molecular Structure; Podophyllotoxin; Structure-Activity Relationship; Triazoles

2012
Synthesis and anticancer activity of glucosylated podophyllotoxin derivatives linked via 4β-triazole rings.
    Molecules (Basel, Switzerland), 2013, Nov-13, Volume: 18, Issue:11

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Humans; Molecular Structure; Podophyllotoxin; Triazoles

2013
A convergent synthesis of alkyne-azide cycloaddition derivatives of 4-α,β-2-propyne podophyllotoxin depicting potent cytotoxic activity.
    European journal of medicinal chemistry, 2014, Apr-22, Volume: 77

    Topics: Alkynes; Antineoplastic Agents; Apoptosis; Azides; Cell Proliferation; Cell Survival; Cyclization; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Podophyllotoxin; Structure-Activity Relationship; Triazoles; Tumor Cells, Cultured

2014
Synthesis and evaluation of biological properties of ferrocenyl-podophyllotoxin conjugates.
    Dalton transactions (Cambridge, England : 2003), 2017, Aug-22, Volume: 46, Issue:33

    Topics: Amides; Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Chemistry Techniques, Synthetic; Esterases; Ferrous Compounds; Humans; Metallocenes; Models, Molecular; Molecular Conformation; Podophyllotoxin; Protein Multimerization; Protein Structure, Quaternary; Triazoles; Tubulin

2017
4β-amidotriazole linked podophyllotoxin congeners: DNA topoisomerase-IIα inhibition and potential anticancer agents for prostate cancer.
    European journal of medicinal chemistry, 2018, Jan-20, Volume: 144

    Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Proliferation; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Humans; Male; Membrane Potential, Mitochondrial; Molecular Docking Simulation; Molecular Structure; Podophyllotoxin; Prostatic Neoplasms; Reactive Oxygen Species; Structure-Activity Relationship; Topoisomerase II Inhibitors; Triazoles; Tumor Cells, Cultured

2018
Click chemistry-based synthesis and cytotoxic activity evaluation of 4α-triazole acetate podophyllotoxin derivatives.
    Chemical biology & drug design, 2019, Volume: 93, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Binding Sites; Cell Line, Tumor; Click Chemistry; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; G2 Phase Cell Cycle Checkpoints; Humans; Molecular Dynamics Simulation; Podophyllotoxin; Protein Structure, Tertiary; Reactive Oxygen Species; Structure-Activity Relationship; Triazoles; Tubulin

2019
Synthesis of podophyllotoxin-glycosyl triazoles
    Natural product research, 2021, Volume: 35, Issue:1

    Topics: Antineoplastic Agents; Cell Line, Tumor; Click Chemistry; Cycloaddition Reaction; Drug Screening Assays, Antitumor; Humans; Methane; Molecular Docking Simulation; Podophyllotoxin; Silver; Structure-Activity Relationship; Topoisomerase II Inhibitors; Triazoles

2021
Triazole/thiadiazole substituted 4'-demethylepipodophyllotoxin derivatives induced apoptosis in HeLa cells by up-regulating TMEM133.
    European journal of pharmacology, 2021, Aug-15, Volume: 905

    Topics: Animals; Antineoplastic Agents; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Checkpoints; DNA Damage; DNA Repair; DNA Topoisomerases, Type II; Etoposide; Female; Gene Expression Regulation; Gene Knockout Techniques; HeLa Cells; Histones; Humans; Male; Mice, Inbred C57BL; Podophyllotoxin; Thiadiazoles; Triazoles; Up-Regulation

2021