Page last updated: 2024-08-21

podophyllotoxin and thiourea

podophyllotoxin has been researched along with thiourea in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fang, J; Wang, C; Wu, Z; Zhao, Y; Zhu, L1
Fang, JH; Ge, CW; Wang, CN; Wu, ZH; Zhao, Y; Zhu, L1
Lee, KH; Li, WQ; Liu, YQ; Morris-Natschke, SL; Qian, K; Tian, J; Wang, CY; Wang, XL; Yang, L; Zhou, XW1
Wu, Z; Zhang, Y; Zhao, Y; Zhu, L1
Amula, SB; Jeengar, MK; Kamal, A; Kumar, NP; Naidu, VG; Nekkanti, S; Reddy, TS; Shankaraiah, N1

Other Studies

5 other study(ies) available for podophyllotoxin and thiourea

ArticleYear
Synthesis and antitumor activity of novel aroylthiourea derivatives of podophyllotoxin.
    Investigational new drugs, 2012, Volume: 30, Issue:1

    Topics: Antigens, Neoplasm; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Proliferation; DNA Topoisomerases, Type II; DNA-Binding Proteins; DNA, Catenated; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flow Cytometry; G2 Phase Cell Cycle Checkpoints; HCT116 Cells; Hep G2 Cells; Humans; Inhibitory Concentration 50; M Phase Cell Cycle Checkpoints; Molecular Structure; Podophyllotoxin; Staining and Labeling; Structure-Activity Relationship; Thiourea; Time Factors

2012
Synthesis and evaluation of aroylthiourea derivatives of 4-β-amino-4'-O-demethyl-4-desoxypodophyllotoxin as novel topoisomerase II inhibitors.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:3

    Topics: Antineoplastic Agents; Cell Cycle; Cell Proliferation; DNA Topoisomerases, Type II; HCT116 Cells; Hep G2 Cells; Humans; Neoplasms; Podophyllotoxin; Podophyllum; Thiourea; Topoisomerase II Inhibitors

2011
Design, synthesis and potent cytotoxic activity of novel podophyllotoxin derivatives.
    Bioorganic & medicinal chemistry, 2013, Apr-15, Volume: 21, Issue:8

    Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; KB Cells; Podophyllotoxin; Structure-Activity Relationship; Thiourea; Topoisomerase II Inhibitors

2013
HY-2, a novel DNA topoisomerase II inhibitor, induces G2/M cell cycle arrest in HCT-116 cells.
    Journal of chemotherapy (Florence, Italy), 2014, Volume: 26, Issue:6

    Topics: Apoptosis; Cell Proliferation; Cell Survival; G2 Phase Cell Cycle Checkpoints; HCT116 Cells; Humans; M Phase Cell Cycle Checkpoints; Podophyllotoxin; Thiourea; Topoisomerase II Inhibitors

2014
One-pot synthesis of podophyllotoxin-thiourea congeners by employing NH₂SO₃H/NaI: Anticancer activity, DNA topoisomerase-II inhibition, and apoptosis inducing agents.
    Bioorganic & medicinal chemistry letters, 2015, Oct-01, Volume: 25, Issue:19

    Topics: Amides; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Podophyllotoxin; Sodium Iodide; Structure-Activity Relationship; Sulfur Oxides; Thiourea; Topoisomerase II Inhibitors

2015