Page last updated: 2024-08-21

podophyllotoxin and stilbenes

podophyllotoxin has been researched along with stilbenes in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19902 (15.38)18.7374
1990's3 (23.08)18.2507
2000's5 (38.46)29.6817
2010's3 (23.08)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hamel, E; Ho, HH; Lin, CM; Pettit, GR1
Chu, PS; Dempcy, RO; Hamel, E; Lin, CM; Pettit, GR; Schmidt, JM; Singh, SB1
Sackett, DL1
D'Amato, RJ; Flynn, E; Hamel, E; Lin, CM1
Day, BW; Hamel, E; Rosenkranz, HS; ter Haar, E1
Kovar, P; Ng, SC; Rosenberg, SH; Tahir, SK1
Chaudhuri, AR; Hausheer, FH; LudueƱa, RF; Schwarz, PM; Seetharamalu, P1
Gupta, MM; Khanuja, SP; Kumar, JK; Negi, AS; Srivastava, V1
Burnett, JC; Day, BW; Gussio, R; Hamel, E; Hermone, AR; McGrath, C; Nguyen, TL; Wipf, P; Zaharevitz, DW1
Chen, P; Hu, Z; Lewis, A; Li, C; Li, PK; Pandit, B; Rich, W; Sackett, DL; Schaefer, K; Sun, Y1
Akhmanova, A; Doodhi, H; Kapitein, LC; Katrukha, EA; Meijering, E; Mohan, R; Smal, I; Steinmetz, MO1
Nandagopal, K; Routh, S1
Defant, A; Mancini, I1

Reviews

3 review(s) available for podophyllotoxin and stilbenes

ArticleYear
Podophyllotoxin, steganacin and combretastatin: natural products that bind at the colchicine site of tubulin.
    Pharmacology & therapeutics, 1993, Volume: 59, Issue:2

    Topics: 4-Butyrolactone; Animals; Antineoplastic Agents, Phytogenic; Bibenzyls; Binding Sites; Cell Division; Lignans; Podophyllotoxin; Polymers; Stilbenes; Structure-Activity Relationship; Tubulin

1993
Plant-based anticancer molecules: a chemical and biological profile of some important leads.
    Bioorganic & medicinal chemistry, 2005, Nov-01, Volume: 13, Issue:21

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Humans; Paclitaxel; Podophyllotoxin; Stilbenes

2005
Patent Survey of Resveratrol, Taxol, Podophyllotoxin, Withanolides and Their Derivatives Used in Anticancer Therapy.
    Recent patents on biotechnology, 2017, Volume: 11, Issue:2

    Topics: Humans; Neoplasms; Paclitaxel; Patents as Topic; Podophyllotoxin; Resveratrol; Stilbenes; Withanolides

2017

Other Studies

10 other study(ies) available for podophyllotoxin and stilbenes

ArticleYear
Antimitotic natural products combretastatin A-4 and combretastatin A-2: studies on the mechanism of their inhibition of the binding of colchicine to tubulin.
    Biochemistry, 1989, Aug-22, Volume: 28, Issue:17

    Topics: Animals; Bibenzyls; Binding Sites; Brain; Cattle; Colchicine; Guanosine Triphosphate; Kinetics; Macromolecular Substances; Mitosis; Models, Structural; Plant Extracts; Podophyllotoxin; Protein Binding; Stilbenes; Tropolone; Tubulin

1989
Interactions of tubulin with potent natural and synthetic analogs of the antimitotic agent combretastatin: a structure-activity study.
    Molecular pharmacology, 1988, Volume: 34, Issue:2

    Topics: Animals; Anisoles; Antineoplastic Agents; Bibenzyls; Binding Sites; Binding, Competitive; Colchicine; Leukemia L1210; Mice; Mitosis; Podophyllotoxin; Protein Binding; Stilbenes; Structure-Activity Relationship; Tubulin

1988
Interactions of 2-methoxyestradiol, an endogenous mammalian metabolite, with unpolymerized tubulin and with tubulin polymers.
    Biochemistry, 1996, Jan-30, Volume: 35, Issue:4

    Topics: 2-Methoxyestradiol; Binding Sites; Colchicine; Estradiol; Glutamates; Kinetics; Microtubule-Associated Proteins; Microtubules; Podophyllotoxin; Polymers; Stilbenes; Tubulin

1996
Computational and molecular modeling evaluation of the structural basis for tubulin polymerization inhibition by colchicine site agents.
    Bioorganic & medicinal chemistry, 1996, Volume: 4, Issue:10

    Topics: Antineoplastic Agents, Phytogenic; Bibenzyls; Binding Sites; Colchicine; Models, Molecular; Paclitaxel; Podophyllotoxin; Protein Conformation; Software; Stilbenes; Tubulin; Tubulin Modulators

1996
Rapid colchicine competition-binding scintillation proximity assay using biotin-labeled tubulin.
    BioTechniques, 2000, Volume: 29, Issue:1

    Topics: Aminophenols; Bibenzyls; Binding Sites; Binding, Competitive; Biotinylation; Colchicine; Demecolcine; Mebendazole; Microspheres; Podophyllotoxin; Scintillation Counting; Solvents; Stilbenes; Streptavidin; Sulfonamides; Tritium; Tubulin; Yttrium

2000
The interaction of the B-ring of colchicine with alpha-tubulin: a novel footprinting approach.
    Journal of molecular biology, 2000, Nov-10, Volume: 303, Issue:5

    Topics: Amino Acid Sequence; Animals; Bibenzyls; Binding Sites; Cattle; Chromatography, High Pressure Liquid; Colchicine; Fluorescence; Models, Molecular; Molecular Sequence Data; Peptide Fragments; Podophyllotoxin; Protein Conformation; Protein Footprinting; Stilbenes; Tropolone; Tryptophan; Tubulin; Urea

2000
A common pharmacophore for a diverse set of colchicine site inhibitors using a structure-based approach.
    Journal of medicinal chemistry, 2005, Sep-22, Volume: 48, Issue:19

    Topics: 2-Methoxyestradiol; 4-Butyrolactone; Aminophenols; Binding Sites; Chalcone; Colchicine; Cyclopropanes; Estradiol; Indans; Lignans; Models, Molecular; Molecular Structure; Nocodazole; Podophyllotoxin; Protein Binding; Stilbenes; Structure-Activity Relationship; Sulfonamides; Thiazoles; Tubulin; Tubulin Modulators

2005
Structure-activity-relationship studies of conformationally restricted analogs of combretastatin A-4 derived from SU5416.
    Bioorganic & medicinal chemistry, 2006, Oct-01, Volume: 14, Issue:19

    Topics: Antineoplastic Agents, Phytogenic; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; DNA, Neoplasm; Drug Screening Assays, Antitumor; Female; Humans; Indoles; Isomerism; Magnetic Resonance Spectroscopy; Molecular Conformation; Podophyllotoxin; Pyrroles; Stilbenes; Structure-Activity Relationship; Tubulin

2006
End-binding proteins sensitize microtubules to the action of microtubule-targeting agents.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, May-28, Volume: 110, Issue:22

    Topics: Bridged Bicyclo Compounds, Heterocyclic; Cellular Senescence; Colchicine; Depsipeptides; Green Fluorescent Proteins; HeLa Cells; Humans; Lactones; Microscopy, Fluorescence; Microtubule-Associated Proteins; Microtubules; Models, Biological; Paclitaxel; Podophyllotoxin; Statistics, Nonparametric; Stilbenes; Tubulin Modulators; Vinblastine

2013
Design, Synthesis and Cancer Cell Growth Inhibition Evaluation of New Aminoquinone Hybrid Molecules.
    Molecules (Basel, Switzerland), 2019, Jun-14, Volume: 24, Issue:12

    Topics: Amides; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Docking Simulation; Molecular Structure; Naphthoquinones; Neoplasms; Podophyllotoxin; Pyridines; Quinolines; rho-Associated Kinases; Stilbenes; Structure-Activity Relationship; Topoisomerase II Inhibitors; Tubulin; Tubulin Modulators

2019