Compounds > podophyllotoxin
Page last updated: 2024-08-21

podophyllotoxin and spermine

podophyllotoxin has been researched along with spermine in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bailly, C; Barret, JM; Goetsch, L; Guilbaud, N; Guminski, Y; Imbert, T; Kruczynski, A; Le Pape, A; Pesnel, S; Pillon, A; Vandenberghe, I1
Annereau, JP; Bailly, C; Barret, JM; Bréand, S; Brel, V; Broussas, M; Dumontet, C; Guilbaud, N; Guminski, Y; Imbert, T; Vispé, S1
Bailly, C; Gentry, AC; Graves, DE; Jablonsky, MJ; Osheroff, N; Pitts, SL1
Bailly, C; Bal-Mahieu, C; Boulet, E; Guilbaud, N; Kruczynski, A; Lansiaux, A; Lartigau, E; Leblond, P; Meignan, S; Pillon, A; Sarrazin, T1
Convertino, M; De Vivo, M; Greco, ML; Marchetti, C; Minarini, A; Minniti, E; Palermo, G; Riccardi, L; Rosini, M; Simoni, E; Sissi, C1

Other Studies

5 other study(ies) available for podophyllotoxin and spermine

ArticleYear
Preclinical activity of F14512, designed to target tumors expressing an active polyamine transport system.
    Investigational new drugs, 2011, Volume: 29, Issue:1

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Biological Transport; Cell Death; Cell Line, Tumor; Flow Cytometry; Fluorescence; Humans; Immunohistochemistry; Mice; Podophyllotoxin; Polyamines; Spermine; Xenograft Model Antitumor Assays

2011
A fluorescent biomarker of the polyamine transport system to select patients with AML for F14512 treatment.
    Leukemia research, 2010, Volume: 34, Issue:10

    Topics: Animals; Antigens, CD34; Biogenic Polyamines; Biological Transport; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; Flow Cytometry; Fluorescent Dyes; Humans; Leukemia, Myeloid, Acute; Oxadiazoles; Podophyllotoxin; Spermine

2010
Interactions between the etoposide derivative F14512 and human type II topoisomerases: implications for the C4 spermine moiety in promoting enzyme-mediated DNA cleavage.
    Biochemistry, 2011, Apr-19, Volume: 50, Issue:15

    Topics: Antigens, Neoplasm; Antineoplastic Agents; DNA; DNA Cleavage; DNA Topoisomerases, Type II; DNA-Binding Proteins; Drug Stability; Etoposide; Humans; Podophyllotoxin; Protein Binding; Spermine; Structure-Activity Relationship

2011
Activity of the polyamine-vectorized anti-cancer drug F14512 against pediatric glioma and neuroblastoma cell lines.
    Investigational new drugs, 2014, Volume: 32, Issue:5

    Topics: Animals; Antineoplastic Agents; Carboplatin; Cell Line, Tumor; Cell Survival; Cisplatin; Etoposide; Female; Glioma; Humans; Liver Neoplasms; Melphalan; Mice, Inbred BALB C; Neuroblastoma; Podophyllotoxin; Radiation, Ionizing; Spermine

2014
An optimized polyamine moiety boosts the potency of human type II topoisomerase poisons as quantified by comparative analysis centered on the clinical candidate F14512.
    Chemical communications (Cambridge, England), 2015, Oct-01, Volume: 51, Issue:76

    Topics: DNA; DNA Cleavage; DNA Topoisomerases, Type II; Humans; Models, Molecular; Podophyllotoxin; Spermine; Topoisomerase II Inhibitors

2015