Page last updated: 2024-08-21

podophyllotoxin and rutin

podophyllotoxin has been researched along with rutin in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (7.69)29.6817
2010's10 (76.92)24.3611
2020's2 (15.38)2.80

Authors

AuthorsStudies
Bohlin, L; Huss, U; Perera, P; Ringbom, T; Vasänge, M1
Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P1
Dutta, A; Gupta, ML; Kalita, B1
Gupta, ML; Verma, S1
Bajaj, S; Dutta, S; Flora, SJ; Gupta, ML; Kalita, B; Ranjan, R; Singh, A; Srivastava, NN; Yashavarddhan, MH1
Bajaj, S; Dutta, S; Gupta, ML; Kalita, B; Ranjan, R; Shukla, SK; Singh, A; Srivastava, NN; Suar, M; Yashavarddhan, MH1
Bajaj, S; Gupta, ML; Kalita, B; Ranjan, R; Singh, A; Yashavarddhan, MH1
Dutta, A; Gupta, ML; Verma, S1
Cui, T; Lu, LH; Lu, XP; Peng, LF; Yang, LG; Zhu, ZY1
Gupta, ML; Kalita, B; Ranjan, R1
Gupta, ML; Nadella, V; Pothani, S; Prakash, H; Qadri, SSYH; Ranjan, R; Senthilkumaran, B; Singh, AK1
Gupta, ML; Kumar, K; Verma, S1
Gupta, ML; Kalita, B; Prakash, H; Ranjan, R; Singh, A; Yashavarddhan, MH1

Other Studies

13 other study(ies) available for podophyllotoxin and rutin

ArticleYear
Screening of ubiquitous plant constituents for COX-2 inhibition with a scintillation proximity based assay.
    Journal of natural products, 2002, Volume: 65, Issue:11

    Topics: Acrolein; Alkaloids; Animals; Anthraquinones; Aspirin; Biological Assay; Catalysis; Cinnamomum zeylanicum; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Eugenol; Flavonoids; Indomethacin; Inhibitory Concentration 50; Isoenzymes; Kinetics; Lactones; Models, Molecular; Nitrobenzenes; Oleanolic Acid; Plants, Medicinal; Prostaglandin-Endoperoxide Synthases; Pyrogallol; Steroids; Sulfonamides; Sulfones; Syzygium; Terpenes; Triterpenes; Ursolic Acid

2002
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Bioorganic & medicinal chemistry, 2012, Nov-15, Volume: 20, Issue:22

    Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship

2012
The combination of the active principles of Podophyllum hexandrum supports early recovery of the gastrointestinal system via activation of Nrf2-HO-1 signaling and the hematopoietic system, leading to effective whole-body survival in lethally irradiated mi
    Free radical research, 2015, Volume: 49, Issue:3

    Topics: Animals; Gamma Rays; Gastrointestinal Tract; Hematopoietic System; Heme Oxygenase-1; Mice; NF-E2-Related Factor 2; Oxidative Stress; Plant Extracts; Podophyllotoxin; Podophyllum; Radiation-Protective Agents; Rutin; Signal Transduction; Whole-Body Irradiation

2015
Radiation-induced hematopoietic myelosuppression and genotoxicity get significantly countered by active principles of Podophyllum hexandrum: A study in strain 'A' mice.
    International journal of radiation biology, 2015, Volume: 91, Issue:9

    Topics: Animals; Antioxidants; Apoptosis Regulatory Proteins; Bone Marrow; Chromosome Aberrations; DNA Damage; DNA Fragmentation; Erythropoietin; Female; Free Radical Scavengers; Glucosides; Hematopoiesis; Mice; Mice, Inbred A; Mutagenicity Tests; Myelopoiesis; Phytotherapy; Podophyllotoxin; Podophyllum; Radiation Injuries, Experimental; Radiation-Protective Agents; Rutin

2015
Countering effects of a combination of podophyllotoxin, podophyllotoxin β-D-glucoside and rutin hydrate in minimizing radiation induced chromosomal damage, ROS and apoptosis in human blood lymphocytes.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2016, Volume: 91

    Topics: Apoptosis; Chromosome Aberrations; Glucosides; Humans; Lymphocytes; Podophyllotoxin; Radiation Dosage; Reactive Oxygen Species; Rutin

2016
γH2AX formation kinetics in PBMCs of rabbits exposed to acute and fractionated radiation and attenuation of focus frequency through preadministration of a combination of podophyllotoxin and rutin hydrate.
    Environmental and molecular mutagenesis, 2016, Volume: 57, Issue:6

    Topics: Animals; DNA Breaks, Double-Stranded; Dose-Response Relationship, Radiation; Drug Synergism; Flow Cytometry; Gamma Rays; Genetic Loci; Histones; Kinetics; Leukocytes, Mononuclear; Male; Podophyllotoxin; Rabbits; Radiation Dosage; Radiation-Protective Agents; Rutin; Whole-Body Irradiation

2016
A Combination of Podophyllotoxin and Rutin Attenuates Radiation Induced Gastrointestinal Injury by Negatively Regulating NF-κB/p53 Signaling in Lethally Irradiated Mice.
    PloS one, 2016, Volume: 11, Issue:12

    Topics: Animals; Cyclooxygenase 2; Dinoprostone; Drug Therapy, Combination; Gastrointestinal Tract; Heme Oxygenase-1; Interleukin-6; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Podophyllotoxin; Radiation Injuries; Radiation-Protective Agents; Reactive Oxygen Species; Rutin; Signal Transduction; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53

2016
Podophyllotoxin and rutin in combination prevents oxidative stress mediated cell death and advances revival of mice gastrointestine following lethal radiation injury.
    Free radical research, 2018, Volume: 52, Issue:1

    Topics: Animals; Cell Death; Male; Mice; Oxidative Stress; Podophyllotoxin; Radiation Injuries; Rutin

2018
[A new biflavone from Dysosma versipellis].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2016, Volume: 51, Issue:8

    Topics: Berberidaceae; Flavones; Kaempferols; Podophyllotoxin; Quercetin; Rutin

2016
Combination treatment of podophyllotoxin and rutin promotes mouse Lgr5
    Apoptosis : an international journal on programmed cell death, 2019, Volume: 24, Issue:3-4

    Topics: Animals; beta Catenin; DNA Damage; Drug Therapy, Combination; Inflammation; Intestinal Mucosa; Intestines; Male; Mice; Mice, Inbred C57BL; Podophyllotoxin; Radiation Injuries; Radiation-Protective Agents; Receptors, G-Protein-Coupled; Rutin; Stem Cells; Up-Regulation; Wnt Signaling Pathway

2019
Podophyllotoxin and Rutin Modulate M1 (iNOS+) Macrophages and Mitigate Lethal Radiation (LR) Induced Inflammatory Responses in Mice.
    Frontiers in immunology, 2019, Volume: 10

    Topics: Animals; Cell Differentiation; Cells, Cultured; Cytokines; Gamma Rays; Humans; Immunomodulation; Macrophages; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase Type II; Podophyllotoxin; Radiation Injuries; Rutin; Th1 Cells; Th1-Th2 Balance; Th2 Cells

2019
A combined prophylactic modality of podophyllotoxin and rutin alleviates radiation induced injuries to the lymphohematopoietic system of mice by modulating cytokines, cell cycle progression, and apoptosis.
    Free radical research, 2020, Volume: 54, Issue:7

    Topics: Animals; Apoptosis; Cell Cycle; Cytokines; Drug Combinations; Hematopoietic System; Male; Mice; Mice, Inbred C57BL; Podophyllotoxin; Radiation Injuries, Experimental; Radiation-Protective Agents; Random Allocation; Reactive Nitrogen Species; Reactive Oxygen Species; Rutin

2020
Prophylactic administration of podophyllotoxin and rutin combination assists the revival of radiation-induced hematopoietic suppression in lethally irradiated mice.
    Biochemical and biophysical research communications, 2021, 04-16, Volume: 549

    Topics: Animals; Apoptosis; Bone Marrow; Cell Proliferation; Drug Therapy, Combination; Female; Gamma Rays; Hematopoiesis; Hematopoietic Stem Cells; Mice, Inbred C57BL; Podophyllotoxin; Rutin; Up-Regulation; Wnt Signaling Pathway

2021