Page last updated: 2024-08-21

podophyllotoxin and pentamidine

podophyllotoxin has been researched along with pentamidine in 30 studies

Research

Studies (30)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	14 (46.67)	29.6817
2010's	14 (46.67)	24.3611
2020's	2 (6.67)	2.80

Authors

Authors	Studies
Chibale, K; Croft, SL; Fairlamb, AH; Haupt, H; Kendrick, H; Saravanamuthu, A; Yardley, V	1
Croft, SL; del Rayo Camacho, M; Kirby, GC; Marley, D; Phillipson, JD; Warhurst, DC	1
Bauer, H; Davioud-Charvet, E; Krauth-Siegel, RL; Lee, B; Melchers, J; Rattray, L; Ruppert, T; Yardley, V	1
Alvarez, A; Atherton, R; Coro, J; Little, S; Pérez, R; Rodríguez, H; Súarez, M; Wharton, H; Yardley, V	1
Salem, MM; Werbovetz, KA	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Croft, SL; Gilbert, IH; Gonzalez-Pacanowska, D; Gros, L; Jimenez, CJ; Little, S; Lorente, SO; Rattray, L; Ruiz-Perez, LM; Wharton, H; Yardley, V	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Delfín, DA; Endeshaw, MM; Fotie, J; George, TG; Li, C; Mahasenan, KV; Morgan, RE; Mukherjee, MS; Werbovetz, KA; Yakovich, AJ	1
Bakunov, SA; Bakunova, SM; Barszcz, T; Brun, R; Hall, JE; Tidwell, RR; Wenzler, T; Werbovetz, KA	1
Bakunov, SA; Bakunova, SM; Barszcz, T; Brun, R; Tidwell, RR; Wenzler, T; Werbovetz, KA	2
Delfín, DA; Morgan, RE; Werbovetz, KA; Zhu, X	1
Bakunov, SA; Bakunova, SM; Barzcz, T; Brun, R; Chen, H; Jones, SK; Kumar, EV; Patrick, DA; Tidwell, RR; Wenzler, T; Werbovetz, KA	1
Bakunov, SA; Bakunova, SM; Brun, R; Ghebru, M; Tidwell, RR; Wenzler, T; Werbovetz, KA	1
Baumann, K; Bischof, SK; Bringmann, G; Brun, R; Dreher, J; Gulder, T; Kaiser, M; Moll, H; Müller, S; Stich, A; Winter, C	1
Brun, R; Fotie, J; Gershkovich, P; He, S; Liu, Q; Patrick, DA; Premalatha, K; Reid, CS; Tidwell, RR; Wang, MZ; Wasan, KM; Wenzler, T; Werbovetz, KA	1
Alkhaldi, AA; Chana, A; Dardonville, C; de Koning, HP; Eze, AA; Flores Pérez, EJ; Healy, A; Herrero García, V; Kaiser, M; Ríos Martínez, C; Taladriz, A	1
Kaiser, M; McKeever, C; Rozas, I	1
Arafa, RK; Boykin, DW; Brun, R; Ismail, MA; Jones, SK; Pandharkar, T; Patrick, DA; Tidwell, RR; Wenzler, T; Werbovetz, KA; Zhu, X	1
Bakunov, SA; Bakunova, SM; Barszcz, T; Boykin, DW; Brun, R; Jones, SK; Kumar, A; Patrick, DA; Tidwell, RR; Wenzler, T; Werbovetz, KA	1
Brun, R; Harel, D; Prinz, H; Schepmann, D; Schmidt, TJ; Wünsch, B	1
Bakunov, SA; Bakunova, SM; Brun, R; Patrick, DA; Tidwell, RR; Wenzler, T	1
Brun, R; Buckner, FS; Chatterjee, AK; Creason, SA; Duster, NA; Gelb, MH; Gillespie, JR; Glynne, R; Hulverson, MA; McQueen, J; Molteni, V; Nagendar, P; Nagle, A; Norcross, NR; Ranade, RM; Supek, F; Tatipaka, HB; Wenzler, T	1
Boykin, DW; Brun, R; Liu, ZY; Wenzler, T; Zhu, X	1
Avery, VM; Baell, JB; Bergström, CA; Charman, SA; Ferrins, L; Gazdik, M; Jones, AJ; Kaiser, M; Rahmani, R; Ryan, E; Sykes, ML; Varghese, S; White, KL	1
Brun, R; Patrick, DA; Tidwell, RR; Wang, MZ; Weiser, PT; Wenzler, T; Yang, S	1
Arroo, RRJ; Beresford, KJM; Bhambra, AS; Burrell-Saward, H; Ruparelia, KC; Tan, HL; Tasdemir, D; Yardley, V	1
Abdelhameed, A; Guo, P; Joice, AC; Li, J; Liao, X; McElroy, CA; Rakotondraibe, L; Slebodnick, C; Werbovetz, KA; Wilson, WD	1
Abdel-Megeed, AM; Avery, VM; Baell, JB; Brown, RW; Hyland, CJT; Jones, AJ; Kaiser, M; Keller, PA; Sykes, ML	1

Other Studies

30 other study(ies) available for podophyllotoxin and pentamidine

Article	Year
Antiprotozoal and cytotoxicity evaluation of sulfonamide and urea analogues of quinacrine. Bioorganic & medicinal chemistry letters, 2001, Oct-08, Volume: 11, Issue:19 Topics: Animals; Antiprotozoal Agents; Leishmania; Parasitic Sensitivity Tests; Plasmodium; Quinacrine; Sulfonamides; Trypanosoma; Urea	2001
Assessment of the antiprotozoal activity of Galphimia glauca and the isolation of new nor-secofriedelanes and nor-friedelanes. Journal of natural products, 2002, Volume: 65, Issue:10 Topics: Animals; Antiprotozoal Agents; Drug Screening Assays, Antitumor; Galphimia; Leishmania donovani; Plasmodium falciparum; Spectrum Analysis; Triterpenes; Trypanosoma brucei brucei; Tumor Cells, Cultured	2002
Irreversible inactivation of trypanothione reductase by unsaturated Mannich bases: a divinyl ketone as key intermediate. Journal of medicinal chemistry, 2005, Nov-17, Volume: 48, Issue:23 Topics: Animals; Antimalarials; Antiprotozoal Agents; Chromatography, High Pressure Liquid; Dimethyl Sulfoxide; Drug Storage; Glutathione; Glutathione Reductase; Humans; Ketones; Leishmania donovani; Magnetic Resonance Spectroscopy; Mannich Bases; NADH, NADPH Oxidoreductases; Plasmodium falciparum; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Thioredoxin-Disulfide Reductase; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosoma cruzi	2005
Alkyl-linked bis-THTT derivatives as potent in vitro trypanocidal agents. Bioorganic & medicinal chemistry letters, 2006, Mar-01, Volume: 16, Issue:5 Topics: Alkylation; Animals; Carboxylic Acids; Leishmania donovani; Molecular Structure; Plasmodium falciparum; Structure-Activity Relationship; Thiadiazines; Trypanocidal Agents; Trypanosoma brucei rhodesiense	2006
Isoflavonoids and other compounds from Psorothamnus arborescens with antiprotozoal activities. Journal of natural products, 2006, Volume: 69, Issue:1 Topics: Animals; Antiprotozoal Agents; California; Chlorocebus aethiops; Fabaceae; Genistein; Inhibitory Concentration 50; Isoflavones; Leishmania donovani; Molecular Structure; Plant Roots; Plants, Medicinal; Trypanosoma brucei brucei; Vero Cells	2006
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Evaluation of azasterols as anti-parasitics. Journal of medicinal chemistry, 2006, Oct-05, Volume: 49, Issue:20 Topics: Animals; Antimalarials; Azasteroids; Leishmania donovani; Methyltransferases; Plasmodium falciparum; Stereoisomerism; Sterols; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosoma cruzi	2006
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Synthesis, biological evaluation, and molecular modeling of 3,5-substituted-N1-phenyl-N4,N4-di-n-butylsulfanilamides as antikinetoplastid antimicrotubule agents. Bioorganic & medicinal chemistry, 2007, Sep-15, Volume: 15, Issue:18 Topics: Animals; Cell Line; Kinetoplastida; Leishmania donovani; Microtubules; Models, Chemical; Models, Molecular; Structure-Activity Relationship; Sulfanilamides; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African; Tubulin Modulators	2007
Synthesis and in vitro antiprotozoal activity of bisbenzofuran cations. Journal of medicinal chemistry, 2007, Nov-15, Volume: 50, Issue:23 Topics: Animals; Antimalarials; Benzofurans; Cations; Leishmania donovani; Plasmodium falciparum; Rats; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei rhodesiense	2007
Synthesis and antiprotozoal activity of cationic 2-phenylbenzofurans. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Animals; Antiprotozoal Agents; Benzofurans; Cations; Disease Models, Animal; Leishmania; Mice; Molecular Structure; Structure-Activity Relationship; Trypanosoma; Trypanosomiasis	2008
Redox-active dinitrodiphenylthioethers against Leishmania: synthesis, structure-activity relationships and mechanism of action studies. Bioorganic & medicinal chemistry, 2009, Jan-15, Volume: 17, Issue:2 Topics: Animals; Antiprotozoal Agents; Chlorocebus aethiops; Leishmania donovani; Macrophages, Peritoneal; Membrane Potential, Mitochondrial; Mice; Mice, Inbred Strains; Oxidation-Reduction; Quantitative Structure-Activity Relationship; Reactive Oxygen Species; Sulfides; Vero Cells	2009
Synthesis and antiprotozoal activities of dicationic bis(phenoxymethyl)benzenes, bis(phenoxymethyl)naphthalenes, and bis(benzyloxy)naphthalenes. European journal of medicinal chemistry, 2009, Volume: 44, Issue:9 Topics: Animals; Antiprotozoal Agents; Benzene; Cell Survival; Leishmania donovani; Mice; Myoblasts; Naphthalenes; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats; Structure-Activity Relationship; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	2009
Synthesis and antiprotozoal activity of pyridyl analogues of pentamidine. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Animals; Antiprotozoal Agents; Female; Leishmania donovani; Mice; Pentamidine; Plasmodium falciparum; Pyridines; Rats; Structure-Activity Relationship	2009
Synthesis and antiprotozoal activity of cationic 1,4-diphenyl-1H-1,2,3-triazoles. Journal of medicinal chemistry, 2010, Jan-14, Volume: 53, Issue:1 Topics: Amidines; Animals; Antiprotozoal Agents; Cell Line; Cell Survival; Disease Models, Animal; Female; Leishmania donovani; Mice; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Rats; Stereoisomerism; Structure-Activity Relationship; Triazoles; Trypanosoma brucei rhodesiense	2010
QSAR guided synthesis of simplified antiplasmodial analogs of naphthylisoquinoline alkaloids. European journal of medicinal chemistry, 2010, Volume: 45, Issue:11 Topics: Alkaloids; Animals; Antimalarials; Isoquinolines; Magnetic Resonance Spectroscopy; Models, Molecular; Plasmodium falciparum; Quantitative Structure-Activity Relationship; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared	2010
Synthesis and antitrypanosomal evaluation of derivatives of N-benzyl-1,2-dihydroquinolin-6-ols: Effect of core substitutions and salt formation. Bioorganic & medicinal chemistry, 2011, Jan-01, Volume: 19, Issue:1 Topics: Animals; Cyclization; Mice; Quinolines; Salts; Structure-Activity Relationship; Trypanocidal Agents	2011
Synthesis and structure-activity analysis of new phosphonium salts with potent activity against African trypanosomes. Journal of medicinal chemistry, 2012, Mar-22, Volume: 55, Issue:6 Topics: Carrier Proteins; Cell Line; Drug Resistance; Humans; Models, Molecular; Nucleoside Transport Proteins; Organophosphorus Compounds; Pentamidine; Quantitative Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense	2012
Aminoalkyl derivatives of guanidine diaromatic minor groove binders with antiprotozoal activity. Journal of medicinal chemistry, 2013, Feb-14, Volume: 56, Issue:3 Topics: Animals; Antiprotozoal Agents; Guanidine; Nucleic Acid Denaturation; Plasmodium falciparum; Trypanosoma brucei rhodesiense	2013
Synthesis and antiprotozoal activity of dicationic m-terphenyl and 1,3-dipyridylbenzene derivatives. Journal of medicinal chemistry, 2013, Jul-11, Volume: 56, Issue:13 Topics: Animals; Antiprotozoal Agents; Benzene; Chagas Disease; Female; Leishmania donovani; Mice; Mice, Inbred Strains; Models, Chemical; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyridines; Structure-Activity Relationship; Terphenyl Compounds; Trypanosoma cruzi	2013
Synthesis and antiprotozoal activities of benzyl phenyl ether diamidine derivatives. European journal of medicinal chemistry, 2013, Volume: 67 Topics: Animals; Antiprotozoal Agents; Dose-Response Relationship, Drug; Leishmania donovani; Mice; Molecular Structure; Myoblasts; Parasitic Sensitivity Tests; Pentamidine; Phenyl Ethers; Plasmodium falciparum; Rats; Structure-Activity Relationship; Trypanosoma brucei rhodesiense; Trypanosomiasis	2013
Natural product derived antiprotozoal agents: synthesis, biological evaluation, and structure-activity relationships of novel chromene and chromane derivatives. Journal of medicinal chemistry, 2013, Sep-26, Volume: 56, Issue:18 Topics: Antiprotozoal Agents; Biological Products; Chemistry Techniques, Synthetic; Chromans; Inhibitory Concentration 50; Structure-Activity Relationship	2013
Antiprotozoal activity of dicationic 3,5-diphenylisoxazoles, their prodrugs and aza-analogues. Bioorganic & medicinal chemistry, 2014, Jan-01, Volume: 22, Issue:1 Topics: Animals; Antiprotozoal Agents; Isoxazoles; Mice; Molecular Structure; Plasmodium falciparum; Prodrugs; Structure-Activity Relationship; Trypanosomiasis, African	2014
Substituted 2-phenylimidazopyridines: a new class of drug leads for human African trypanosomiasis. Journal of medicinal chemistry, 2014, Feb-13, Volume: 57, Issue:3 Topics: Administration, Oral; Animals; Biological Availability; Cell Line, Tumor; Cell Membrane Permeability; Databases, Chemical; Dogs; Female; Humans; Imidazoles; Madin Darby Canine Kidney Cells; Mice; Microsomes, Liver; Pyridines; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	2014
Synthesis and antiparasitic activity of new bis-arylimidamides: DB766 analogs modified in the terminal groups. European journal of medicinal chemistry, 2014, Aug-18, Volume: 83 Topics: Amides; Animals; Antiparasitic Agents; Cell Line; Chemistry Techniques, Synthetic; Leishmania; Plasmodium falciparum; Rats; Trypanosoma	2014
Pyridyl benzamides as a novel class of potent inhibitors for the kinetoplastid Trypanosoma brucei. Journal of medicinal chemistry, 2014, Aug-14, Volume: 57, Issue:15 Topics: Animals; Benzamides; Cell Line; HEK293 Cells; Humans; Microsomes, Liver; Myoblasts; Pyridines; Rats; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense	2014
Synthesis of novel amide and urea derivatives of thiazol-2-ethylamines and their activity against Trypanosoma brucei rhodesiense. Bioorganic & medicinal chemistry, 2016, 06-01, Volume: 24, Issue:11 Topics: Amides; Amines; Animals; Antiprotozoal Agents; Cell Survival; Dose-Response Relationship, Drug; Humans; Mice; Microsomes, Liver; Molecular Structure; Myoblasts; Parasitic Sensitivity Tests; Rats; Structure-Activity Relationship; Thiazoles; Trypanosoma brucei rhodesiense; Urea	2016
Synthesis and antitrypanosomal activities of novel pyridylchalcones. European journal of medicinal chemistry, 2017, Mar-10, Volume: 128 Topics: Animals; Cells, Cultured; Chagas Disease; Chalcones; Humans; Leishmania donovani; Leishmaniasis, Visceral; Models, Molecular; Molecular Structure; Parasitic Sensitivity Tests; Propane; Pyridines; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi	2017
Synthesis and antileishmanial evaluation of thiazole orange analogs. Bioorganic & medicinal chemistry letters, 2020, 01-01, Volume: 30, Issue:1 Topics: Animals; Benzothiazoles; Drug Discovery; Leishmaniasis, Visceral; Quinolines	2020
Investigation of thiazolyl-benzothiophenamides as potential agents for African sleeping sickness. RSC medicinal chemistry, 2020, Dec-17, Volume: 11, Issue:12 Topics:	2020