Compounds > podophyllotoxin

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podophyllotoxin and mitoxantrone

podophyllotoxin has been researched along with mitoxantrone in 14 studies

Research

Studies (14)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (14.29)	18.7374
1990's	1 (7.14)	18.2507
2000's	8 (57.14)	29.6817
2010's	3 (21.43)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ	1
Leung, CH; Li, G; Liu, C; Ma, DL; Wang, HD; Wu, KJ; Zhong, HJ	1
Ellis, AL; Gewirtz, DA; Povirk, LF; Randolph, JK; Swerdlow, PS; Yalowich, JC; Yanovich, S	1
Glisson, B; Gupta, R; Hodges, P; Ross, W	1
Hande, KR	1
Kreuzer, KN; O'Reilly, EK	1
Blokhin, DIu	1
Seiter, K	1
Albarello, A; Ballerini, F; Balocco, M; Canepa, L; Canepa, P; Clavio, M; Garrone, A; Gobbi, M; Michelis, GL; Miglino, M; Pierri, I; Varaldo, R	1
Martin, R; Schippling, S	1

Reviews

4 review(s) available for podophyllotoxin and mitoxantrone

Article	Year
Clinical applications of anticancer drugs targeted to topoisomerase II. Biochimica et biophysica acta, 1998, Oct-01, Volume: 1400, Issue:1-3 Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Enzyme Inhibitors; Humans; Mitoxantrone; Molecular Structure; Podophyllotoxin; Topoisomerase II Inhibitors	1998
[The multidrug tumor cell resistance phenotype caused by the impaired cell death program]. Vestnik Rossiiskoi akademii meditsinskikh nauk, 2004, Issue:12 Topics: Anthracyclines; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Disease Progression; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Genes, p53; Humans; Mitoxantrone; Neoplasms; Phenotype; Podophyllotoxin; Radiation Tolerance; Tumor Cells, Cultured	2004
Toxicity of the topoisomerase II inhibitors. Expert opinion on drug safety, 2005, Volume: 4, Issue:2 Topics: Antineoplastic Agents; Cardiovascular Diseases; Daunorubicin; Doxorubicin; Enzyme Inhibitors; Epirubicin; Etoposide; Humans; Idarubicin; Leukemia; Middle Aged; Mitoxantrone; Mucositis; Podophyllotoxin; Teniposide; Topoisomerase II Inhibitors; Vascular Diseases	2005
[Stem cell therapy in multiple sclerosis: a clinical update]. Zeitschrift fur Rheumatologie, 2009, Volume: 68, Issue:3 Topics: Animals; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Purging; Bone Marrow Transplantation; Carmustine; Central Nervous System; Clinical Trials, Phase II as Topic; Controlled Clinical Trials as Topic; Cytarabine; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Magnetic Resonance Imaging; Melphalan; Mitoxantrone; Multicenter Studies as Topic; Multiple Sclerosis; Podophyllotoxin; Risk Assessment; Survival Rate; Treatment Outcome	2009

Other Studies

10 other study(ies) available for podophyllotoxin and mitoxantrone

Article	Year
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nature chemical biology, 2009, Volume: 5, Issue:10 Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Identification of potent Yes1 kinase inhibitors using a library screening approach. Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15 Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship	2013
Structure-based identification of a NEDD8-activating enzyme inhibitor via drug repurposing. European journal of medicinal chemistry, 2018, Jan-01, Volume: 143 Topics: Adenocarcinoma; Apoptosis; Caco-2 Cells; Cell Line; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Discovery; Drug Evaluation, Preclinical; Enzyme Inhibitors; Humans; Mitoxantrone; Models, Molecular; Molecular Structure; NEDD8 Protein; Structure-Activity Relationship; Tumor Suppressor Protein p53; Ubiquitin-Activating Enzymes	2018
Expression of protein-associated DNA damage in the alkaline elution assay in the absence of enzymatic deproteinization. Cancer communications, 1989, Volume: 1, Issue:3 Topics: Animals; Cell Line; DNA Damage; DNA Replication; DNA Topoisomerases, Type II; DNA, Neoplasm; Endopeptidase K; Etoposide; Humans; Hydrogen-Ion Concentration; Leukemia L1210; Liver Neoplasms, Experimental; Mice; Mitoxantrone; Podophyllotoxin; Protein Binding; Rats; Serine Endopeptidases; Teniposide; Tumor Cells, Cultured	1989
Cross-resistance to intercalating agents in an epipodophyllotoxin-resistant Chinese hamster ovary cell line: evidence for a common intracellular target. Cancer research, 1986, Volume: 46, Issue:4 Pt 2 Topics: Aminoacridines; Amsacrine; Animals; Anthraquinones; Cell Line; Cricetinae; Cricetulus; DNA; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Female; Intercalating Agents; Mitoxantrone; Ovary; Podophyllotoxin	1986
A unique type II topoisomerase mutant that is hypersensitive to a broad range of cleavage-inducing antitumor agents. Biochemistry, 2002, Jun-25, Volume: 41, Issue:25 Topics: Amino Acid Sequence; Amino Acid Substitution; Amsacrine; Antineoplastic Agents; Bacteriophage T4; Binding Sites; DNA Damage; DNA Topoisomerases, Type II; DNA, Superhelical; Ellipticines; Enzyme Inhibitors; Filtration; Glycine; Mitoxantrone; Molecular Sequence Data; Oxolinic Acid; Podophyllotoxin; Point Mutation; Topoisomerase II Inhibitors; Valine	2002
Ifosfamide, epirubicin, etoposide (IEV) and autologous peripheral blood progenitor cell transplant: a feasible and effective salvage treatment for lymphoid malignancies. Oncology reports, 2005, Volume: 14, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cytarabine; Epirubicin; Etoposide; Female; Hodgkin Disease; Humans; Ifosfamide; Lymphoma, Non-Hodgkin; Male; Melphalan; Middle Aged; Mitoxantrone; Multiple Myeloma; Odds Ratio; Peripheral Blood Stem Cell Transplantation; Podophyllotoxin; Recurrence; Remission Induction; Salvage Therapy; Time Factors; Transplantation Conditioning; Treatment Outcome	2005