Page last updated: 2024-08-21

podophyllotoxin and glucose, (beta-d)-isomer

podophyllotoxin has been researched along with glucose, (beta-d)-isomer in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19905 (23.81)18.7374
1990's1 (4.76)18.2507
2000's7 (33.33)29.6817
2010's8 (38.10)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Falkson, G; Falkson, HC; van den Bergh, JA; van der Merwe, AM; van Dyk, JJ; van Eden, EB1
Batz, K; Brunner, KW; Cavalli, F; Ryssel, HJ; Sonntag, RW1
Stähelin, HF; von Wartburg, A1
Alberto, P; Giger, K; Nagel, G; Senn, HJ; Sonntag, RW1
Burandt, CL; Canel, C; Dayan, FE; Ganzera, M; Khan, IA; Moraes, RM; Rimando, A1
Huang, J; Nagatsu, A; Ogihara, Y; Zhao, C1
Canel, C; Dayan, FE; Kuhajek, JM; Moraes, RM; Watson, SB1
Ding, YJ; Jiang, M; Yu, M; Zhai, YG; Zhang, H; Zhang, QY; Zhao, CQ1
Liao, F; Lin, YD; Qi, YL; Zhao, CQ; Zuo, MX1
Ge, T; Li, Q; Yan, G1
Berim, A; Ebel, R; Petersen, M; Schneider, B1
Gao, J; Li, H; Liu, Y; Wang, L; Yu, M; Zhai, Y; Zhao, C1
Chen, H; Hua, HM; Li, ZL; Liu, XQ; Sun, YJ; Zhou, W1
Ali, A; Amin, H; Chakraborty, S; Goswami, A; Kitchlu, S; Nalli, Y; Nayak, D; Rah, B; Zilla, MK1
Gupta, ML; Verma, S1
Bajaj, S; Dutta, S; Flora, SJ; Gupta, ML; Kalita, B; Ranjan, R; Singh, A; Srivastava, NN; Yashavarddhan, MH1
Ali, A; Amin, H; Chakraborty, S; Gandhi, SG; Gopinath, V; Goswami, A; Katoch, A; Kumar, A; Kumar, LD; Mahajan, V; Nayak, D; Rah, B; Rasool, RU; Zilla, MK1
Chen, DW; Chen, RD; Dai, JG; Xie, KB; Zhang, YJ1
Ding, ZT; Hu, JM; Jiang, ZH; Kong, QH; Li, HM; Yang, L; Yang, XZ; Zhou, J; Zi, CT1
EMMENEGGER, H; RENZ, J; RUTSCHMANN, J; STAEHELIN, H2

Reviews

1 review(s) available for podophyllotoxin and glucose, (beta-d)-isomer

ArticleYear
The chemical and biological route from podophyllotoxin glucoside to etoposide: ninth Cain memorial Award lecture.
    Cancer research, 1991, Jan-01, Volume: 51, Issue:1

    Topics: Aldehydes; Antineoplastic Agents; Cell Division; Cyclosporins; Etoposide; Glucosides; Growth Inhibitors; History, 19th Century; History, 20th Century; Plants, Medicinal; Plants, Toxic; Podophyllotoxin; Podophyllum; Structure-Activity Relationship; Teniposide

1991

Other Studies

20 other study(ies) available for podophyllotoxin and glucose, (beta-d)-isomer

ArticleYear
A clinical trial of the oral form of 4'-demethyl-epipodophyllotoxin-beta-D ethylidene glucoside (NSC 141540) VP 16-213.
    Cancer, 1975, Volume: 35, Issue:4

    Topics: Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Administration, Oral; Breast Neoplasms; Carcinoma; Colonic Neoplasms; Female; Glucosides; Humans; Leukemia, Myeloid; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Mesothelioma; Neoplasm Metastasis; Neoplasms; Ovarian Neoplasms; Podophyllotoxin; Remission, Spontaneous; Urinary Bladder Neoplasms

1975
[Initial results with a epipodophyllotoxin derivative VP 16-213 in the treatment of acute leukemia].
    Schweizerische medizinische Wochenschrift, 1975, Feb-22, Volume: 105, Issue:8

    Topics: Acute Disease; Adolescent; Adult; Aged; Chemical Phenomena; Chemistry; Chronic Disease; Drug Evaluation; Female; Glucosides; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Male; Middle Aged; Podophyllotoxin; Remission, Spontaneous

1975
Experience with 4'-demethylepipodo-phyllotoxin 9-(4,6-o-2-thenylidene-beta-D-glucopyranoside); VM-26; NSC-122819 in the treatment of malignant lymphosis.
    European journal of cancer, 1974, Volume: 10, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Blood Platelet Disorders; Dose-Response Relationship, Drug; Female; Glucosides; Glycosides; Hodgkin Disease; Humans; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Male; Middle Aged; Podophyllotoxin; Remission, Spontaneous; Thiophenes

1974
High yield of podophyllotoxin from leaves of Podophyllum peltatum by in situ conversion of podophyllotoxin 4- O-beta-D-glucopyranoside.
    Planta medica, 2001, Volume: 67, Issue:1

    Topics: Glucosides; Magnoliopsida; Plant Leaves; Podophyllotoxin

2001
Two new podophyllotoxin glucosides from Sinopodophyllum emodi (Wall.) Ying.
    Chemical & pharmaceutical bulletin, 2001, Volume: 49, Issue:6

    Topics: Glucosides; Lignans; Magnoliopsida; Molecular Structure; Podophyllotoxin; Spectrum Analysis

2001
Podophyllum peltatum possesses a beta-glucosidase with high substrate specificity for the aryltetralin lignan podophyllotoxin.
    Biochimica et biophysica acta, 2003, Mar-21, Volume: 1646, Issue:1-2

    Topics: beta-Glucosidase; Disaccharides; Enzyme Stability; Glucosides; Hydrogen-Ion Concentration; Molecular Structure; Plant Leaves; Podophyllotoxin; Podophyllum peltatum; Substrate Specificity; Temperature

2003
Apoptosis induced by one new podophyllotoxin glucoside in human carcinoma cells.
    Toxicology, 2005, Aug-15, Volume: 212, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Glucosides; HeLa Cells; Humans; Plant Extracts; Podophyllotoxin; Podophyllum; Rhizome

2005
Cytotoxicity, apoptosis induction, and mitotic arrest by a novel podophyllotoxin glucoside, 4DPG, in tumor cells.
    Acta pharmacologica Sinica, 2005, Volume: 26, Issue:8

    Topics: Apoptosis; Caspase 3; Caspases; Cell Division; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Activation; Glucosides; HeLa Cells; Humans; K562 Cells; Microscopy, Electron, Transmission; Microtubules; Molecular Structure; Podophyllotoxin; Polymers; Time Factors

2005
A fragmentation study of podophyllotoxin and its 4'-demethyl-4beta-substituted derivatives by electrospray ionization ion-trap time-of-flight tandem mass spectrometry.
    Rapid communications in mass spectrometry : RCM, 2007, Volume: 21, Issue:17

    Topics: Glucosides; Podophyllotoxin; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization

2007
UDP-glucose:(6-methoxy)podophyllotoxin 7-O-glucosyltransferase from suspension cultures of Linum nodiflorum.
    Phytochemistry, 2008, Volume: 69, Issue:2

    Topics: Flax; Glucosides; Glucosyltransferases; Molecular Structure; Podophyllotoxin; Substrate Specificity; Uridine Diphosphate Glucose

2008
Cytotoxicity and apoptosis induced by a new podophyllotoxin glucoside in human hepatoma (HepG2) cells.
    Canadian journal of physiology and pharmacology, 2010, Volume: 88, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Cell Death; Cell Shape; DNA Fragmentation; Dose-Response Relationship, Drug; Glucosides; Hep G2 Cells; Humans; Podophyllotoxin; Proto-Oncogene Proteins c-bcl-2

2010
Three new cytotoxic aryltetralin lignans from Sinopodophyllum emodi.
    Bioorganic & medicinal chemistry letters, 2011, Jun-15, Volume: 21, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Berberidaceae; Cell Line, Tumor; Cell Survival; Glucosides; HeLa Cells; Humans; Inhibitory Concentration 50; Lignans; Magnetic Resonance Spectroscopy; Plant Roots; Podophyllotoxin

2011
4'-Demethyl-deoxypodophyllotoxin glucoside isolated from Podophyllum hexandrum exhibits potential anticancer activities by altering Chk-2 signaling pathway in MCF-7 breast cancer cells.
    Chemico-biological interactions, 2014, Dec-05, Volume: 224

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Checkpoint Kinase 2; G2 Phase Cell Cycle Checkpoints; Glucosides; Humans; Molecular Docking Simulation; Phosphorylation; Podophyllotoxin; Podophyllum; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Signal Transduction; Tubulin Modulators

2014
Radiation-induced hematopoietic myelosuppression and genotoxicity get significantly countered by active principles of Podophyllum hexandrum: A study in strain 'A' mice.
    International journal of radiation biology, 2015, Volume: 91, Issue:9

    Topics: Animals; Antioxidants; Apoptosis Regulatory Proteins; Bone Marrow; Chromosome Aberrations; DNA Damage; DNA Fragmentation; Erythropoietin; Female; Free Radical Scavengers; Glucosides; Hematopoiesis; Mice; Mice, Inbred A; Mutagenicity Tests; Myelopoiesis; Phytotherapy; Podophyllotoxin; Podophyllum; Radiation Injuries, Experimental; Radiation-Protective Agents; Rutin

2015
Countering effects of a combination of podophyllotoxin, podophyllotoxin β-D-glucoside and rutin hydrate in minimizing radiation induced chromosomal damage, ROS and apoptosis in human blood lymphocytes.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2016, Volume: 91

    Topics: Apoptosis; Chromosome Aberrations; Glucosides; Humans; Lymphocytes; Podophyllotoxin; Radiation Dosage; Reactive Oxygen Species; Rutin

2016
Inhibition of Twist1-mediated invasion by Chk2 promotes premature senescence in p53-defective cancer cells.
    Cell death and differentiation, 2017, Volume: 24, Issue:7

    Topics: Animals; Biomarkers, Tumor; Cell Line, Tumor; Cell Proliferation; Cellular Senescence; Checkpoint Kinase 2; Cyclin-Dependent Kinase Inhibitor p21; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glucosides; Humans; Mice; Models, Biological; Neoplasm Invasiveness; Neoplasm Metastasis; Nuclear Proteins; Podophyllotoxin; Promoter Regions, Genetic; Transcription, Genetic; Tumor Suppressor Protein p53; Twist-Related Protein 1

2017
[Enzymatic glycosylation of 4'-demethylepipodophyllotoxin].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2017, Volume: 42, Issue:12

    Topics: Aloe; Glucosides; Glycosides; Glycosylation; Glycosyltransferases; Podophyllotoxin

2017
Glucoside Derivatives Of Podophyllotoxin: Synthesis, Physicochemical Properties, And Cytotoxicity.
    Drug design, development and therapy, 2019, Volume: 13

    Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Glucosides; Humans; Inhibitory Concentration 50; Neoplasms; Podophyllotoxin; Structure-Activity Relationship

2019
[On the chemistry and pharmacology of Podophyllum glucoside and its derivatives. 1].
    Arzneimittel-Forschung, 1961, Volume: 11

    Topics: Glucosides; Glycosides; Podophyllum

1961
[On the chemistry and pharmacology of Podophyllum glucoside and its derivatives. 2].
    Arzneimittel-Forschung, 1961, Volume: 11

    Topics: Glucosides; Glycosides; Podophyllum

1961