Page last updated: 2024-08-21

podophyllotoxin and fluorouracil

podophyllotoxin has been researched along with fluorouracil in 65 studies

Research

Studies (65)

TimeframeStudies, this research(%)All Research%
pre-199036 (55.38)18.7374
1990's8 (12.31)18.2507
2000's6 (9.23)29.6817
2010's14 (21.54)24.3611
2020's1 (1.54)2.80

Authors

AuthorsStudies
Hansch, C; Khwaja, TA; Selassie, CD1
Jurd, L; Narayanan, VL; Paull, KD1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Chen, SW; Liu, J; Tian, X; Xiang, R1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, SW; Ding, YL; Huang, WT; Hui, L; Liu, J; Liu, JF1
Chanda, D; Chanotiya, CS; Gupta, A; Kaur, T; Khan, F; Luqman, S; Negi, AS; Prakasham, AP; Saxena, AK; Shanker, K; Yadav, DK1
Chen, X; Hu, K; Ren, J; Wu, L; Xin, WQ1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Chen, Y; Liu, L; Nie, X; Shi, D; Wang, J; Wang, Y; Wei, G; Zhang, L; Zheng, C1
Behera, C; Chanda, D; Fatima, K; Gupta, AK; Hasanain, M; Khwaja, S; Kour, A; Luqman, S; Mondhe, DM; Negi, AS; Sarkar, J; Shanker, K; Singh, A1
Liu, Y; Xu, Z; Zhao, SJ1
Bender, RA; Chabner, BA; Cohen, M; Doroshow, JH; Hande, KR; Locker, GY; Murinson, DS; Myers, CE; Zwelling, LA1
Walker, MD; Weiss, HD1
Brunner, KW; Cavalli, F; Gerber, A; Ryssel, HJ; Sonntag, RW; Tschopp, L1
Soloway, MS1
Baron, A; Blic, V; Garcia-Giralt, E; Gautier, H; Huguenin, P; Jouve, M; Langlois, A; Morin, P; Palangie, T; Pouillart, P; Regensberg, C1
Dombernowsky, P; Nissen, NI1
Amiel, JL; Baron, A; Huguenin, P; Laparre, Ch; Mathé, G; Morin, P; Parrot, R; Pouillart, P; Schwarzenberg, L2
Ehrsson, H; Eksborg, S1
Iwabuchi, M; Takahashi, K1
Carde, P; Ganem, G; Gouyette, A1
Perroud, HM1
Niell, HB; Soloway, MS; Wood, CA1
Bezwoda, WR; Derman, DP; Kew, M; Weaving, A1
Shapiro, JR; Shapiro, WR1
Athanassiades, P; Bacoyiannes, H; Kontoyiannes, D1
Herrmann, R; Osswald, H; Youssef, M1
Barrada, A; Case, J; Fiscella, R; Fishman, G; Peyman, GA; Thomas, A1
Freshney, RI; Kaye, SB; Merry, S1
Bellamy, AS; Hill, BT1
Alburquerque Carbuccia, H; Madrigal Alonso, P; Perez Manga, G1
Demitrish, M; Duffin, H; Enochs, K; Groshko, G; Lockhard, C; Maniscalco-Greb, E; Vaughn, CB1
von Krogh, G1
Abbou, C; Auvert, J; Botto, H; Garcia-Giralt, E; Hannoun, M; Jouve, M; Lachand, AT; Morin, P; Palangie, T; Pouillart, P1
Niccoli, V; Serrao, L1
Dercksen, MW; Dirkson, MK; Gerritsen, WR; Pinedo, HM; Rodenhuis, S; Schaasberg, WP; Slaper-Cortenbach, IC; van der Schoot, CE; von dem Borne, AE1
Stone, KM1
Smotkin, D1
Wen, YJ1
Bistoletti, P; Löwhagen, GB; Persson, G; Rylander, E; Von Krogh, G1
Beutner, KR; Ferenczy, A1
Chen, SW; Tian, X; Tu, YQ1
Tian, X; Tu, YQ; Yao, XJ; Zhang, FM1
Atallah, AN; Batista, CS; da Silva, EM; Saconato, H1
Brassard, P; Ouhoummane, N; Rodier, C; Steben, M1
Bailly, C; Bal-Mahieu, C; Bertheau, C; Chevalier, D; Gros, A; Horn, S; Lansiaux, A; Lartigau, E; Meignan, S; Mouawad, F; Rysman, B; Sarrazin, T1
Cherpelis, B; Rudnick, EW; Thareja, S1
Chen, SW; Guan, XW; Hui, L; Jin, YX; Xiang, R1
Jing, YX; Qi, SN; Shi, RY; Wang, LS; Yang, YJ; Yao, J; Yuan, HQ1
Babu, S; Biankin, AV; Chang, DK; Escobar-Hoyos, LF; K Bai, JD; Kawalerski, RR; Leiton, CV; Otsuka, Y; Pan, CH; Scampavia, L; Shroyer, KR; Spicer, T; Sridharan, B; Torrente Gonçalves, M; Woo, M1
Bunney, MH1
Redman, JF; Turley, JT1
Anderson, JM; Hutchison, J1
Clément, F1
Krieg, R; Ringleb, D; Sauer, D1
Bosnar, M; Krieg, R; Ringleb, D; Sauer, D; Steckenmesser, R1
Furue, H; Hattori, T; Kubo, A; Nakao, I; Yamana, T1
Bettley, FR1
GOLDENBERG, DM1
DEJAGER, ME; FALKSON, G1
FALKSON, G; SCHULZ, EJ1

Reviews

13 review(s) available for podophyllotoxin and fluorouracil

ArticleYear
1,2,3-Triazole-containing hybrids as potential anticancer agents: Current developments, action mechanisms and structure-activity relationships.
    European journal of medicinal chemistry, 2019, Dec-01, Volume: 183

    Topics: Antineoplastic Agents; Humans; Molecular Structure; Neoplasms; Structure-Activity Relationship; Triazoles

2019
Antineoplastic drugs: clinical pharmacology and therapeutic use.
    Drugs, 1978, Volume: 16, Issue:1

    Topics: Alkaloids; Alkylating Agents; Antibiotics, Antineoplastic; Antineoplastic Agents; Azacitidine; Bleomycin; Cisplatin; Cyclophosphamide; Cytarabine; Drug Interactions; Fluorouracil; Humans; Kinetics; Methotrexate; Podophyllotoxin

1978
Chemotherapy in the treatment of malignant brain tumors.
    Advances in neurology, 1975, Volume: 13

    Topics: Adrenal Cortex Hormones; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Cyclophosphamide; Disease Models, Animal; Drug Evaluation; Drug Evaluation, Preclinical; Drug Therapy, Combination; Fluorouracil; Humans; Methotrexate; Nitrogen Mustard Compounds; Nitrosourea Compounds; Plicamycin; Podophyllotoxin; Procarbazine; Vincristine

1975
Intravesical and systemic chemotherapy of murine bladder cancer.
    Cancer research, 1977, Volume: 37, Issue:8 Pt 2

    Topics: Animals; Antineoplastic Agents; BCG Vaccine; Carcinoma, Transitional Cell; Cisplatin; Cyclophosphamide; Dactinomycin; Doxorubicin; Drug Therapy, Combination; Ethoglucid; FANFT; Female; Fluorouracil; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Neoplasms, Experimental; Podophyllotoxin; Thiotepa; Urinary Bladder Neoplasms

1977
Drug level monitoring: cytostatics.
    Journal of chromatography, 1985, May-10, Volume: 340

    Topics: Alkylating Agents; Aminoacridines; Amsacrine; Anthraquinones; Antibiotics, Antineoplastic; Antimetabolites; Antineoplastic Agents; Bleomycin; Busulfan; Chlorambucil; Chromatography, Gas; Chromatography, Liquid; Cisplatin; Cyclophosphamide; Cytarabine; Fluorouracil; Humans; Mass Spectrometry; Melphalan; Methotrexate; Mitomycins; Monitoring, Physiologic; Nitrosourea Compounds; Podophyllotoxin; Purines; Thiotepa; Vinca Alkaloids

1985
[Prolonged intravenous infusion chemotherapy. General review of theoretical bases and results].
    Bulletin du cancer, 1985, Volume: 72, Issue:6

    Topics: Antineoplastic Agents; Bleomycin; Cell Cycle; Cisplatin; Clinical Trials as Topic; Cytarabine; Doxorubicin; Fluorouracil; Humans; Infusions, Parenteral; Neoplasms; Podophyllotoxin; Time Factors; Vinca Alkaloids

1985
Principles of brain tumor chemotherapy.
    Seminars in oncology, 1986, Volume: 13, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Brain Neoplasms; Carbon Radioisotopes; Carmustine; Cell Line; Cisplatin; Dose-Response Relationship, Drug; Drug Resistance; Fluorouracil; Glioma; Humans; Hydroxyurea; Infusions, Intra-Arterial; Karyotyping; Kinetics; Mannitol; Methotrexate; Podophyllotoxin; Procarbazine; Rats; Tumor Stem Cell Assay

1986
[Human papillomavirus infections in pregnancy].
    La Clinica terapeutica, 1994, Volume: 145, Issue:10

    Topics: Adolescent; Adult; Cryosurgery; Electrocoagulation; Female; Fluorouracil; Humans; Interferons; Laser Therapy; Papillomaviridae; Papillomavirus Infections; Podophyllin; Podophyllotoxin; Pregnancy; Pregnancy Complications, Infectious; Trichloroacetic Acid; Tumor Virus Infections

1994
Human papillomavirus infection and genital warts: update on epidemiology and treatment.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1995, Volume: 20 Suppl 1

    Topics: Condylomata Acuminata; Cryotherapy; Female; Fluorouracil; Humans; Interferons; Laser Therapy; Male; Papillomaviridae; Papillomavirus Infections; Podophyllin; Podophyllotoxin; Sexual Partners; Tumor Virus Infections

1995
Human papillomavirus infection of the vagina.
    Clinical obstetrics and gynecology, 1993, Volume: 36, Issue:1

    Topics: Acetates; Acetic Acid; Biopsy; Colposcopy; Cryosurgery; Diagnosis, Differential; DNA, Viral; Electrosurgery; Female; Fluorouracil; Gynecology; Humans; Interferons; Laser Therapy; Male; Papillomaviridae; Podophyllotoxin; Prevalence; Risk Factors; Trichloroacetic Acid; Tumor Virus Infections; Vaginal Diseases

1993
Therapeutic approaches to genital warts.
    The American journal of medicine, 1997, May-05, Volume: 102, Issue:5A

    Topics: Adjuvants, Immunologic; Aminoquinolines; Antimetabolites; Antiviral Agents; Condylomata Acuminata; Cryotherapy; Drug Therapy, Combination; Electrosurgery; Fluorouracil; Humans; Imiquimod; Injections, Intralesional; Interferons; Keratolytic Agents; Laser Therapy; Papillomaviridae; Papillomavirus Infections; Podophyllin; Podophyllotoxin; Tumor Virus Infections

1997
5-FU for genital warts in non-immunocompromised individuals.
    The Cochrane database of systematic reviews, 2010, Apr-14, Issue:4

    Topics: Administration, Topical; Combined Modality Therapy; Condylomata Acuminata; Cresols; Female; Fluorouracil; Humans; Immunocompetence; Immunosuppressive Agents; Interferon alpha-2; Interferon-alpha; Lasers, Gas; Male; Podophyllotoxin; Randomized Controlled Trials as Topic; Recombinant Proteins; Sulfonic Acids

2010
Oral therapy for nonmelanoma skin cancer in patients with advanced disease and large tumor burden: a review of the literature with focus on a new generation of targeted therapies.
    International journal of dermatology, 2016, Volume: 55, Issue:3

    Topics: Administration, Oral; Anilides; Antineoplastic Agents; Biphenyl Compounds; Capecitabine; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; ErbB Receptors; Erlotinib Hydrochloride; Fluorouracil; Gefitinib; Hedgehog Proteins; Molecular Targeted Therapy; Phthalazines; Podophyllotoxin; Pyridines; Quinazolines; Receptor, IGF Type 1; Retinoids; Skin Neoplasms; Tumor Burden

2016

Trials

6 trial(s) available for podophyllotoxin and fluorouracil

ArticleYear
[Non resectable colonic cancer. Results from a test of chemotherapy with simultaneous prescription of VM26, methyl-CCNU and 5 fluoro-uracile (author's transl)].
    La Nouvelle presse medicale, 1978, Jun-24, Volume: 7, Issue:25

    Topics: Adult; Aged; BCG Vaccine; Colonic Neoplasms; Drug Therapy, Combination; Female; Fluorouracil; Humans; Immunotherapy; Lomustine; Male; Middle Aged; Nitrosourea Compounds; Podophyllotoxin; Teniposide

1978
[Prolonged intravenous infusion chemotherapy. General review of theoretical bases and results].
    Bulletin du cancer, 1985, Volume: 72, Issue:6

    Topics: Antineoplastic Agents; Bleomycin; Cell Cycle; Cisplatin; Clinical Trials as Topic; Cytarabine; Doxorubicin; Fluorouracil; Humans; Infusions, Parenteral; Neoplasms; Podophyllotoxin; Time Factors; Vinca Alkaloids

1985
Combination chemotherapy of hepatocellular cancer. Comparison of adriamycin + VM 26 + 5-fluorouracil with mAMSA + VM 26 + 5-fluorouracil.
    Oncology, 1987, Volume: 44, Issue:4

    Topics: Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Clinical Trials as Topic; Doxorubicin; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Podophyllotoxin; Random Allocation; Teniposide; Time Factors

1987
Etoposide (VP-16-213) and cis-dichlorodiammineplatinum (DDP) in advanced breast carcinoma resistant to previous chemotherapy.
    Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1986, Volume: 5, Issue:2

    Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Etoposide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Podophyllotoxin; Vincristine

1986
Podophyllotoxin for condylomata acuminata eradication. Clinical and experimental comparative studies on Podophyllum lignans, colchicine and 5-fluorouracil.
    Acta dermato-venereologica. Supplementum, 1981, Volume: 98

    Topics: Administration, Topical; Animals; Clinical Trials as Topic; Colchicine; Condylomata Acuminata; Ethanol; Female; Fluorouracil; Follow-Up Studies; Humans; Male; Mice; Mice, Hairless; Plants, Medicinal; Plants, Toxic; Podophyllotoxin; Podophyllum; Rabbits; Skin; Skin Neoplasms; Urogenital Neoplasms

1981
Long-term chemotherapy for cancer of the lung.
    Diseases of the chest, 1968, Volume: 53, Issue:5

    Topics: Aged; Carcinoma, Squamous Cell; Catheterization; Clinical Trials as Topic; Fluorouracil; Humans; Injections, Intravenous; Long-Term Care; Lung Neoplasms; Male; Mechlorethamine; Methotrexate; Middle Aged; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllum

1968

Other Studies

47 other study(ies) available for podophyllotoxin and fluorouracil

ArticleYear
Structure-activity relationships of antineoplastic agents in multidrug resistance.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:7

    Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Cricetinae; Dactinomycin; Drug Resistance; Leukemia L1210; Mice; Regression Analysis; Structure-Activity Relationship; Tumor Cells, Cultured

1990
In vivo antitumor activity of 6-benzyl-1,3-benzodioxole derivatives against the P388, L1210, B16, and M5076 murine models.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:10

    Topics: Animals; Antineoplastic Agents; Astrocytoma; Bucladesine; Cell Differentiation; Dioxoles; DNA Topoisomerases, Type I; Leukemia L1210; Leukemia P388; Leukemia, Experimental; Mice; Tubulin

1987
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Synthesis and biological evaluation of novel conjugates of podophyllotoxin and 5-FU as antineoplastic agents.
    Bioorganic & medicinal chemistry, 2009, Apr-15, Volume: 17, Issue:8

    Topics: Animals; Antineoplastic Agents; Cattle; Cell Line, Tumor; DNA; Drug Design; Fluorouracil; HL-60 Cells; Humans; Nuclear Magnetic Resonance, Biomolecular; Podophyllotoxin

2009
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Synthesis and biological evaluation of conjugates of deoxypodophyllotoxin and 5-FU as inducer of caspase-3 and -7.
    European journal of medicinal chemistry, 2012, Volume: 49

    Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 7; Cell Line, Tumor; Drugs, Chinese Herbal; Enzyme Activation; Fluorouracil; G2 Phase Cell Cycle Checkpoints; Humans; M Phase Cell Cycle Checkpoints; Neoplasms; Podophyllotoxin

2012
Synthesis and anticancer activity of 2-benzylidene indanones through inhibiting tubulin polymerization.
    Bioorganic & medicinal chemistry, 2012, May-01, Volume: 20, Issue:9

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Benzodioxoles; Benzylidene Compounds; Binding Sites; Cell Line, Tumor; Cell Proliferation; Computer Simulation; Humans; Indans; Mice; Protein Structure, Tertiary; Tubulin; Tubulin Modulators

2012
Synthesis and biological evaluation of novel 4β-(1,3,4-oxadiazole-2-amino)-podophyllotoxin derivatives.
    Bioorganic & medicinal chemistry letters, 2012, Jul-15, Volume: 22, Issue:14

    Topics: Animals; Cell Line; Cell Survival; Gene Expression Regulation, Enzymologic; Humans; Molecular Structure; Podophyllotoxin; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

2012
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Synthesis and biological evaluation of novel podophyllotoxin-NSAIDs conjugates as multifunctional anti-MDR agents against resistant human hepatocellular carcinoma Bel-7402/5-FU cells.
    European journal of medicinal chemistry, 2017, May-05, Volume: 131

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle; Cell Line; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Liver Neoplasms; Molecular Structure; Podophyllotoxin; Structure-Activity Relationship

2017
Antiproliferative efficacy of curcumin mimics through microtubule destabilization.
    European journal of medicinal chemistry, 2018, May-10, Volume: 151

    Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Curcumin; Drug Screening Assays, Antitumor; Female; Humans; Male; Mice; Microtubules; Neoplasms

2018
[Therapeutic results using VP 16-213 alone or in combination with 5-fluorouracil in liver cancer (hepatoma)].
    Schweizerische medizinische Wochenschrift, 1977, Dec-31, Volume: 107, Issue:52

    Topics: Adult; Aged; Carcinoma, Hepatocellular; Drug Therapy, Combination; Etoposide; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Middle Aged; Podophyllotoxin

1977
Combination chemotherapy with 4'Demethylepipodophyllotoxin 9-(4,6-0-ethylidene-beta-D-glucopyranoside), VP 16-213 (NSC 141540) in L1210 leukemia.
    European journal of cancer, 1976, Volume: 12, Issue:3

    Topics: Animals; Antineoplastic Agents; Carmustine; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Drug Therapy, Combination; Etoposide; Female; Fluorouracil; Leukemia L1210; Male; Mercaptopurine; Methotrexate; Mice; Mice, Inbred DBA; Podophyllotoxin; Vincristine

1976
[Chemotherapeutic combinations of mutually potentializing drugs. 1-Application to the treatment of breast cancers].
    La Nouvelle presse medicale, 1975, Mar-08, Volume: 4, Issue:10

    Topics: Aged; Alopecia; Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Neurologic Manifestations; Nitrosourea Compounds; Podophyllotoxin; Vincristine; Vomiting

1975
[Chemotherapeutic combinations of mutually potentiating drugs. 2-Application to the treatment of bronchial cancers].
    La Nouvelle presse medicale, 1975, Mar-08, Volume: 4, Issue:10

    Topics: Adult; Aged; Alopecia; Antineoplastic Agents; Bronchial Neoplasms; Carcinoma, Squamous Cell; Drug Synergism; Drug Therapy, Combination; Fluorouracil; Humans; Middle Aged; Nitrosourea Compounds; Podophyllotoxin; Vincristine

1975
[Kinetics of etoposide cytotoxicity against mouse P388 leukemia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:11

    Topics: Animals; Bleomycin; Cell Cycle; Cell Survival; Cisplatin; Colony-Forming Units Assay; Cytarabine; Doxorubicin; Etoposide; Fluorouracil; Leukemia P388; Leukemia, Experimental; Melphalan; Mice; Peplomycin; Podophyllotoxin; Tumor Stem Cell Assay; Vinblastine

1985
[The treatment of warts today].
    Therapeutische Umschau. Revue therapeutique, 1989, Volume: 46, Issue:2

    Topics: Bleomycin; Condylomata Acuminata; Cryosurgery; Electrosurgery; Fluorouracil; Humans; Keratolytic Agents; Laser Therapy; Podophyllotoxin; Tretinoin; Warts

1989
Effect of concentration and time of drug exposure on clonal growth of murine bladder cancer.
    Urology, 1985, Volume: 25, Issue:3

    Topics: Animals; Antineoplastic Agents; Bleomycin; Cell Line; Cisplatin; Colony-Forming Units Assay; Disease Models, Animal; Doxorubicin; FANFT; Female; Fluorouracil; Maytansine; Methotrexate; Mice; Mice, Inbred C3H; Mitomycin; Mitomycins; Podophyllotoxin; Streptozocin; Time Factors; Trichothecenes; Tumor Stem Cell Assay; Urinary Bladder Neoplasms

1985
Timing- and sequence-dependent synergism between etoposide and methotrexate or etoposide, methotrexate and 5-fluorouracil in advanced leukemia L1210.
    Cancer letters, 1985, Volume: 29, Issue:3

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Drug Synergism; Etoposide; Female; Fluorouracil; Leukemia L1210; Methotrexate; Mice; Mice, Inbred Strains; Podophyllotoxin; Time Factors

1985
Evaluation of intravitreal 5-fluorouracil, vincristine, VP 16, doxorubicin, and thiotepa in primate eyes.
    Ophthalmic surgery, 1984, Volume: 15, Issue:9

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Electroretinography; Etoposide; Fluorouracil; Macaca fascicularis; Podophyllotoxin; Retina; Thiotepa; Vincristine; Vitreous Body

1984
Cross-resistance to cytotoxic drugs in human glioma cell lines in culture.
    British journal of cancer, 1984, Volume: 50, Issue:6

    Topics: Antineoplastic Agents; Cell Line; Cell Survival; Dactinomycin; Doxorubicin; Drug Resistance; Fluorouracil; Glioma; Humans; Melphalan; Podophyllotoxin; Vincristine

1984
Establishment of an etoposide-resistant human epithelial tumour cell line in vitro: characterization of patterns of cross-resistance and drug sensitivities.
    International journal of cancer, 1984, May-15, Volume: 33, Issue:5

    Topics: Carcinoma, Squamous Cell; Cell Line; Cisplatin; DNA, Neoplasm; Drug Resistance; Etoposide; Fluorouracil; Humans; Podophyllotoxin; Teniposide; Tongue Neoplasms; Vincristine; X-Rays

1984
Adriamycin and VP16-213 combination treatment for breast cancer previously treated by the CMF regimen.
    Cancer chemotherapy and pharmacology, 1982, Volume: 7, Issue:2-3

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Resistance; Drug Therapy, Combination; Etoposide; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Neoplasm Metastasis; Podophyllotoxin

1982
VP-16 and adriamycin in patients with advanced breast cancer.
    American journal of clinical oncology, 1982, Volume: 5, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Alopecia; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Dexamethasone; Doxorubicin; Drug Therapy, Combination; Etoposide; Female; Fluorouracil; Humans; Leukopenia; Male; Methotrexate; Middle Aged; Podophyllotoxin; Prednisone; Thrombocytopenia; Vincristine; Vomiting

1982
Combined chemotherapy in the management of metastatic bladder cancer.
    British journal of urology, 1981, Volume: 53, Issue:4

    Topics: Doxorubicin; Drug Evaluation; Drug Therapy, Combination; Fluorouracil; Humans; Mitomycins; Neoplasm Metastasis; Podophyllotoxin; Teniposide; Urinary Bladder Neoplasms

1981
Expression of adhesion molecules on CD34+ cells: CD34+ L-selectin+ cells predict a rapid platelet recovery after peripheral blood stem cell transplantation.
    Blood, 1995, Jun-01, Volume: 85, Issue:11

    Topics: Adult; Antigens, CD; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Bone Marrow; Bone Marrow Cells; Carboplatin; Carmustine; Cell Adhesion Molecules; Cell Movement; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Epirubicin; Etoposide; Female; Fluorouracil; Gene Expression; Granulocyte Colony-Stimulating Factor; Hematopoiesis; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Ifosfamide; L-Selectin; Leukocyte Count; Male; Melphalan; Middle Aged; Neoplasms; Neutrophils; Platelet Count; Podophyllotoxin; Receptors, Very Late Antigen; Thiotepa

1995
[Application of crossed assay design in test of drug sensitivity in vitro in combined chemotherapy of liver cancer].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1993, Volume: 15, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cisplatin; Doxorubicin; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Liver Neoplasms; Mitomycin; Podophyllotoxin; Tumor Cells, Cultured

1993
[Genital papillomavirus infection. A diagnostic and therapeutic dilemma].
    Lakartidningen, 1993, Nov-17, Volume: 90, Issue:46

    Topics: Adult; Condylomata Acuminata; Diagnosis, Differential; Female; Fluorouracil; Humans; Male; Papillomaviridae; Penile Neoplasms; Podophyllotoxin; Uterine Cervical Neoplasms

1993
Synthesis and cytotoxic activity of novel derivatives of 4'-demethylepipodophyllotoxin.
    Bioorganic & medicinal chemistry letters, 2004, Oct-18, Volume: 14, Issue:20

    Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Etoposide; Fluorouracil; Humans; Podophyllotoxin; Structure-Activity Relationship

2004
Synthesis and biological evaluation of new 4beta-5-Fu-substituted 4'-demethylepipodophyllotoxin derivatives.
    Molecules (Basel, Switzerland), 2006, Nov-02, Volume: 11, Issue:11

    Topics: Animals; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Drug Design; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Inhibitory Concentration 50; Mice; Podophyllotoxin; Structure-Activity Relationship

2006
Temporal trends in genital warts among individuals covered by the public prescription drug insurance plan in the province of Quebec, Canada, from 1998 to 2007.
    Journal of lower genital tract disease, 2013, Volume: 17, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminoquinolines; Antineoplastic Agents, Phytogenic; Antiviral Agents; Condylomata Acuminata; Drug Prescriptions; Drug Utilization; Female; Fluorouracil; Humans; Imiquimod; Incidence; Insurance Claim Review; Male; Middle Aged; Podophyllotoxin; Prevalence; Quebec; Young Adult

2013
The antitumor drug F14512 enhances cisplatin and ionizing radiation effects in head and neck squamous carcinoma cell lines.
    Oral oncology, 2014, Volume: 50, Issue:2

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Carcinoma, Squamous Cell; Cisplatin; Flow Cytometry; Fluorouracil; Humans; Laryngeal Neoplasms; Microscopy, Confocal; Pharyngeal Neoplasms; Podophyllotoxin; Tongue Neoplasms; Treatment Outcome

2014
Investigation of the anti-angiogenesis effects induced by deoxypodophyllotoxin-5-FU conjugate C069 against HUVE cells.
    Bioorganic & medicinal chemistry letters, 2017, 02-15, Volume: 27, Issue:4

    Topics: Angiogenesis Inhibitors; beta Catenin; Cell Movement; Cell Proliferation; Cell Survival; Down-Regulation; Drugs, Chinese Herbal; Etoposide; Fluorouracil; Human Umbilical Vein Endothelial Cells; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neovascularization, Physiologic; Phosphorylation; Podophyllotoxin; Proto-Oncogene Proteins c-akt

2017
Induction of apoptotic DNA fragmentation mediated by mitochondrial pathway with caspase-3-dependent BID cleavage in human gastric cancer cells by a new nitroxyl spin-labeled derivative of podophyllotoxin.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 90

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Caspase 9; Cell Line, Tumor; Cytochromes c; DNA Fragmentation; Etoposide; Fluorouracil; Humans; Mitochondria; Podophyllotoxin; Spin Labels; Stomach Neoplasms

2017
An unbiased high-throughput drug screen reveals a potential therapeutic vulnerability in the most lethal molecular subtype of pancreatic cancer.
    Molecular oncology, 2020, Volume: 14, Issue:8

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Biomarkers, Tumor; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Deoxycytidine; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Fluorouracil; Gemcitabine; High-Throughput Screening Assays; Humans; Keratin-17; Mice, Inbred C57BL; Microtubules; Paclitaxel; Pancreatic Neoplasms; Podophyllotoxin; Tumor Burden

2020
The treatment of viral warts.
    Drugs, 1977, Volume: 13, Issue:6

    Topics: Cryosurgery; Fluorouracil; Formaldehyde; Humans; Idoxuridine; Immunotherapy; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllum; Salicylates; Warts

1977
Failure of chemotherapy in treatment of giant condyloma acuminata (Buschke-Loewenstein tumor).
    Southern medical journal, 1974, Volume: 67, Issue:6

    Topics: Adult; Condylomata Acuminata; Fluorouracil; Humans; Male; Penile Diseases; Penis; Plant Extracts; Plants, Medicinal; Plants, Toxic; Podophyllum; Styrax; Syndrome; Thiotepa; Urinary Fistula

1974
[The chemotherapy of cancer].
    Praxis, 1967, Dec-07, Volume: 56, Issue:49

    Topics: Adult; Alkylating Agents; Antimetabolites; Antineoplastic Agents; Dactinomycin; Female; Fluorouracil; Hodgkin Disease; Humans; Lung Neoplasms; Male; Melphalan; Methotrexate; Middle Aged; Neoplasms; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllum; Radiography; Sarcoma, Ewing; Thiotepa; Vincristine

1967
[Problems in combined radio-cytostatic therapy. 7. Syncarcinolytic studies using 5-fluorouracil, natulan and proresid in Crocker sarcoma 180 of mice].
    Strahlentherapie, 1969, Volume: 138, Issue:4

    Topics: Alkylating Agents; Animals; Fluorouracil; Methods; Mice; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllin; Podophyllum; Sarcoma 180

1969
[Studies on the understanding of problems of radiologic cytostatic combination treatment. 6. Further syncytostatic studies with 5-fluorouracil, natulan and proresid].
    Strahlentherapie, 1969, Volume: 138, Issue:2

    Topics: Amides; Animals; Antineoplastic Agents; Cyclophosphamide; Ear, External; Female; Fluorouracil; Granulation Tissue; Hydrazines; Mice; Neoplasms; Plants, Medicinal; Plants, Toxic; Podophyllin; Podophyllum; Radiation Effects; Radiation Injuries, Experimental; Radiotherapy Dosage; Statistics as Topic; Tail; Wound Healing

1969
[Clinical studies of the method of application of antineoplastic agents].
    Gan no rinsho. Japan journal of cancer clinics, 1970, Volume: 16, Issue:9

    Topics: Antineoplastic Agents; Blood Cell Count; Bone Marrow Examination; Cyclophosphamide; Fluorouracil; Humans; Hydrazines; Injections; Mitomycins; Neoplasms; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllum

1970
The treatment of skin carcinoma with podophyllum derivatives.
    The British journal of dermatology, 1971, Volume: 84, Issue:1

    Topics: Antineoplastic Agents; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Colchicine; Fluorouracil; Humans; Phytotherapy; Plants, Medicinal; Plants, Toxic; Podophyllin; Podophyllum; Skin Neoplasms

1971
DRUGS OF CURRENT USE FOR THE TREATMENT OF CANCER AND ALLIED DISEASES.
    Diseases of the chest, 1963, Volume: 51

    Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antineoplastic Agents; Aziridines; Busulfan; Colchicine; Dactinomycin; Diethylstilbestrol; Estrogens; Fluorouracil; Gonadal Steroid Hormones; Mercaptopurine; Methotrexate; Mitomycin; Mitomycins; Neoplasms; Podophyllum; Progestins; Quinones; Thiotepa; Triethylenemelamine; Urethane; Vinblastine

1963
CATALASE ACTIVITY IN THE EPIDERMIS OF PATIENTS WITH ADVANCED CANCER.
    Nature, 1964, Apr-11, Volume: 202

    Topics: Antineoplastic Agents; Breast Neoplasms; Carbamates; Catalase; Clinical Enzyme Tests; Cobalt Isotopes; Cyclophosphamide; Drug Therapy; Epidermis; Fluorouracil; Humans; Neoplasms; Podophyllum; Skin

1964
SKIN CHANGES CAUSED BY CANCER CHEMOTHERAPY.
    The British journal of dermatology, 1964, Volume: 76

    Topics: Alopecia; Anti-Bacterial Agents; Antibiotics, Antitubercular; Antineoplastic Agents; Cyclophosphamide; Dactinomycin; Dermatology; Erythema; Ethoglucid; Fluorouracil; Neoplasms; Pathology; Podophyllum; Skin; Sweat Glands; Toxicology; Ulcer

1964