Page last updated: 2024-09-04

podophyllic acid and podophyllotoxin

podophyllic acid has been researched along with podophyllotoxin in 12 studies

Compound Research Comparison

Studies
(podophyllic acid)
Trials
(podophyllic acid)
Recent Studies (post-2010)
(podophyllic acid)
Studies
(podophyllotoxin)
Trials
(podophyllotoxin)
Recent Studies (post-2010) (podophyllotoxin)
12003,119226782

Protein Interaction Comparison

ProteinTaxonomypodophyllic acid (IC50)podophyllotoxin (IC50)
nuclear receptor subfamily 0 group B member 1Homo sapiens (human)2.145
Tubulin alpha-1A chainSus scrofa (pig)0.6733
Tubulin beta chainSus scrofa (pig)0.622
Glucocorticoid receptorHomo sapiens (human)0.014
Tubulin beta-4A chainHomo sapiens (human)1.7233
Tubulin beta chainHomo sapiens (human)1.7233
Cytochrome P450 3A4Homo sapiens (human)0.6
Tubulin alpha-3C chainHomo sapiens (human)1.7233
Cytochrome P450 2C9 Homo sapiens (human)4
Cytochrome P450 2C19Homo sapiens (human)5
Tubulin alpha-1B chainHomo sapiens (human)1.7233
Tubulin alpha-4A chainHomo sapiens (human)1.7233
Tubulin beta-4B chainHomo sapiens (human)1.7233
Tubulin beta-3 chainHomo sapiens (human)1.7233
Tubulin beta-2A chainHomo sapiens (human)1.7233
Tubulin beta-8 chainHomo sapiens (human)1.7233
Calcium-activated potassium channel subunit alpha-1Rattus norvegicus (Norway rat)0.56
Tubulin beta-2B chainBos taurus (cattle)0.8685
Tubulin alpha-3E chainHomo sapiens (human)1.7233
Tubulin alpha-1A chainHomo sapiens (human)1.7233
Similar to alpha-tubulin isoform 1 Bos taurus (cattle)0.907
Similar to alpha-tubulin isoform 1 Bos taurus (cattle)0.7744
Tubulin alpha-1C chainHomo sapiens (human)1.7233
Tubulin beta-6 chainHomo sapiens (human)1.7233
Tubulin beta-2B chainHomo sapiens (human)1.7233
Tubulin beta-1 chainHomo sapiens (human)1.7233

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19905 (41.67)18.7374
1990's1 (8.33)18.2507
2000's4 (33.33)29.6817
2010's2 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Babu, JM; Deevi, DS; Rao, CV; Renuka, B; Sagar, PS; Subrahmanyam, D; Vyas, K1
AUTERHOFF, H; MAY, O1
GRAUWILER, J; MEIER-RUGE, W1
KUHN, M1
NEWTON, KA; WESTBURY, G; WHITE, WF1
GRAUWILER, J; KALBERER, F; MEIER-RUGE, W1
Chen, C; Gao, P; Jia, Z; Yu, J1
Liu, YQ; Qu, JQ; Song, YM; Wang, LF; Wang, PH; Zhang, Q1
Li, DS; Li, Y; Li, YY; Mi, ZY; Tang, YJ1
Li, Y; Tang, YJ; Zhong, JJ1
Castro, MA; Cuevas, C; de la Iglesia-Vicente, J; del Corral, JM; GarcĂ­a, PA; Mollinedo, F; Rojo, MV; San Feliciano, A1
Atallah, AN; Batista, CS; da Silva, EM; Saconato, H1

Reviews

1 review(s) available for podophyllic acid and podophyllotoxin

ArticleYear
5-FU for genital warts in non-immunocompromised individuals.
    The Cochrane database of systematic reviews, 2010, Apr-14, Issue:4

    Topics: Administration, Topical; Combined Modality Therapy; Condylomata Acuminata; Cresols; Female; Fluorouracil; Humans; Immunocompetence; Immunosuppressive Agents; Interferon alpha-2; Interferon-alpha; Lasers, Gas; Male; Podophyllotoxin; Randomized Controlled Trials as Topic; Recombinant Proteins; Sulfonic Acids

2010

Other Studies

11 other study(ies) available for podophyllic acid and podophyllotoxin

ArticleYear
Novel D-ring analogues of podophyllotoxin as potent anti-cancer agents.
    Bioorganic & medicinal chemistry letters, 1998, Jun-02, Volume: 8, Issue:11

    Topics: Antineoplastic Agents; Drug Screening Assays, Antitumor; Humans; Podophyllotoxin; Tumor Cells, Cultured

1998
[Podophylline. II. Presence of 2 podophyllic acids].
    Archiv der Pharmazie und Berichte der Deutschen Pharmazeutischen Gesellschaft, 1958, Volume: 291/63, Issue:4

    Topics: Health Services; Podophyllin; Podophyllotoxin

1958
[THE INFLUENCE OF THE ETHYL HYDRAZIDE OF PODOPHYLLIC ACID (SP-I) ON DOG TISSUES WITH CONSTANT RENEWAL RATES].
    Medicina experimentalis : International journal of experimental medicine, 1963, Volume: 9

    Topics: Antineoplastic Agents; Atrophy; Cell Division; Colon; Dogs; Humans; Male; Mucous Membrane; Pharmacology; Podophyllin; Podophyllotoxin; Podophyllum; Research; Testis

1963
[SYNTHESIS OF NEOPODOPHYLLOTOXIN AND OF PODOPHYLLINIC ACID].
    Experientia, 1963, Aug-15, Volume: 19

    Topics: Chemistry, Pharmaceutical; Pharmacy; Podophyllin; Podophyllotoxin; Podophyllum; Research

1963
INTRA-ARTERIAL ADMINISTRATION OF 2-ETHYLHYDRAZIDE OF PODOPHYLLIC ACID (NSC-72274) IN LOCALIZED MALIGNANT DISEASE.
    Cancer chemotherapy reports, 1964, Volume: 43

    Topics: Antineoplastic Agents; Biomedical Research; Drug Therapy; Hydrazines; Injections, Intra-Arterial; Neoplasms; Podophyllotoxin; Podophyllum; Toxicology

1964
[THE DISTRIBUTION OF THE ANTIMITOTIC AGENT, ETHYLHYDRAZIDE OF PODOPHYLLIC ACID (SP-I 77) IN THE BODY AND IN HUMAN MALIGNANT TUMORS].
    Klinische Wochenschrift, 1964, Oct-15, Volume: 42

    Topics: Animals; Antimitotic Agents; Antineoplastic Agents; Autoradiography; Carcinoma; Colonic Neoplasms; Dogs; Glioma; Humans; Intestines; Kidney; Liver; Lymph Nodes; Metabolism; Neoplasms; Pharmacology; Podophyllin; Podophyllotoxin; Podophyllum; Tritium

1964
[An experimental study on proliferative effects and apoptotic effects of podophyllic acid in K562 cells].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2005, Volume: 28, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Proliferation; Dose-Response Relationship, Drug; Flow Cytometry; Humans; K562 Cells; Plants, Medicinal; Podophyllotoxin; Podophyllum; Time Factors

2005
[Studies on the interaction of the metal complex of hydrazide of podophyllic acid with DNA].
    Guang pu xue yu guang pu fen xi = Guang pu, 2006, Volume: 26, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Cattle; DNA; Podophyllotoxin; Spectrophotometry, Ultraviolet

2006
Novel biotransformation process of podophyllotoxin to produce podophyllic acid and picropodophyllotoxin by Pseudomonas aeruginosa CCTCC AB93066, part II: process optimization.
    Bioresource technology, 2009, Volume: 100, Issue:7

    Topics: Analysis of Variance; Biotransformation; Kinetics; Nitrogen; Peptones; Podophyllotoxin; Pseudomonas aeruginosa; Regression Analysis; Sodium Chloride; Sucrose; Surface Properties

2009
Novel biotransformation process of podophyllotoxin to produce podophyllic acid and picropodophyllotoxin by Pseudomonas aeruginosa CCTCC AB93066. Part I: process development.
    Bioprocess and biosystems engineering, 2009, Volume: 32, Issue:5

    Topics: Biotransformation; Podophyllotoxin; Pseudomonas aeruginosa; Species Specificity

2009
Synthesis and biological evaluation of new podophyllic aldehyde derivatives with cytotoxic and apoptosis-inducing activities.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Aldehydes; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Proliferation; Drug Screening Assays, Antitumor; HT29 Cells; Humans; Lung Neoplasms; Magnetic Resonance Spectroscopy; Melanoma; Molecular Structure; Podophyllotoxin; Tumor Cells, Cultured

2010