plutonium has been researched along with pentetic acid in 249 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 153 (61.45) | 18.7374 |
| 1990's | 15 (6.02) | 18.2507 |
| 2000's | 26 (10.44) | 29.6817 |
| 2010's | 39 (15.66) | 24.3611 |
| 2020's | 16 (6.43) | 2.80 |
| Authors | Studies |
|---|---|
| Atherton, DR; Jones, CW; Lloyd, RD; Mays, CW; Taylor, GN | 1 |
| Derr, SK; Schubert, J | 1 |
| Lushbaugh, CC; Washburn, LC | 2 |
| Guilmette, RA; Lindenbaum, A; Moretti, ES | 1 |
| Howden, S; Stather, JW | 1 |
| Ballou, JE; Buschbom, RL; Dagle, GE; McDonald, KE | 1 |
| Felicetti, SA; Muggenburg, BA; Silbaugh, SA | 1 |
| Guilmette, RA; Lindenbaum, A; Parks, JE | 1 |
| David, AJ; Harrison, JD | 1 |
| Atherton, DR; Bruenger, FW; Jones, CW; Lloyd, RD; Mays, CW; Taylor, GN | 1 |
| Dilley, JV; Mahaffey, JA; McDonald, KE; Sanders, CL | 1 |
| Levdik, TI; Liubchanskii, ER; Nifatov, AP | 1 |
| Liubchanskiĭ, ER; Poplyko, MG | 1 |
| Bhattacharyya, MH; Peterson, DP | 1 |
| Bulman, RA; Griffin, RJ; Russell, AT | 1 |
| Ham, GJ; Loveless, BW; Smith, H; Stradling, GN | 1 |
| Liubchanskiĭ, ER; Sokhranich, AL | 2 |
| Bhattacharyya, MH; Lindenbaum, A; Peterson, DP | 2 |
| Atherton, DR; Boseman, JJ; Lloyd, RD; Mays, CW; Taylor, GN | 1 |
| Atherton, DR; Boseman, JJ; Bruenger, FW; Lloyd, RD; Mays, CW; Stevens, W; Taylor, GN | 1 |
| Fleming, RR; Hall, RM; Poda, GA; Smith, JA | 1 |
| Ballou, JE; Doctor, PG; Gies, RA; Price, KR | 1 |
| Bhattacharyya, MH; Chao, FC; Guilmette, RA; Lindinbaum, A; Peterson, DP | 1 |
| Ohlenschläger, L; Schieferdecker, H; Schmidt-Martin, W | 1 |
| Seidel, A; Takada, K; Volf, V | 1 |
| Lafuma, J; Masse, R; Métvier, H; Nénot, JC; Nolibé, D | 1 |
| Gemenetzis, E; Volf, V | 1 |
| Gruner, R; Seidel, A | 1 |
| McClellan, RO; Mersch, S; Mewhinney, JA; Miglio, JJ; Muggenburg, BA; Ruoff, L; Slauson, DO | 1 |
| Goldin, AS; Lipton, WV | 1 |
| Iashunskiĭ, VG; Levdik, TI; Samoĭlova, OI | 1 |
| Baxter, DW; Kalesperis, GS; Lindenbaum, A; Moretti, ES; Rosenthal, MW; Russell, JJ | 1 |
| Dagle, GE; Gomez, LS; Lebel, JL; Phemister, RD; Watters, RL | 1 |
| Cerny, EA; Moretti, ES; Rahman, YE; Rosenthal, MW | 1 |
| Volf, V | 6 |
| Dagle, GE; McDonald, KE; Olson, RJ; Park, JF; Sanders, CL | 1 |
| Ohlenschläger, L | 1 |
| Lincoln, TA | 1 |
| Bailly, T; Burgada, R; Ellender, M; Gray, SA; Hodgson, A; Leroux, YG; Moody, JC; Pearce, M; Stradling, GN; Wilson, I | 1 |
| Durbin, PW; Gray, SA; Hodgson, A; Moody, JC; Raymond, KN; Rodgers, SJ; Stradling, GN; Turowski, PN; White, DL | 1 |
| Bruenger, FW; Lloyd, RD; Taylor, DM; Taylor, GN | 1 |
| Kabirova, NR; Sokhranich, AL | 2 |
| Chimiak, A; Chomiczewski, K; Przychodzeń, W; Rochalska, M; Szot, Z | 1 |
| Luo, MC; Volf, V | 1 |
| Ellender, M; Gaskin, PW; Gray, SA; Hodgson, A; Moody, JC; Stather, JW; Stradling, GN; Taylor, DM; Volf, V; Wirth, P | 1 |
| Ellender, M; Gray, SA; Hodgson, A; Moody, JC; Stather, JW; Stradling, GN | 2 |
| Jones, CW; Mays, CW; Taylor, GN | 1 |
| Bazhin, AG; Liubchanskiĭ, ER; Nifatov, AP; Siniakov, EG | 2 |
| Ducousso, R; Duserre, C; Gerasimo, P; Metivier, H | 1 |
| Bailey, MR; Collier, C; Gray, SA; Hodgson, A; Moody, JC; Stather, JW; Stradling, GN | 1 |
| Jones, CW; Lloyd, RD; Mays, CW; Packer, SM; Taylor, GN | 1 |
| Bruenger, FW; Durbin, PW; Jones, CW; Lloyd, RD; Mays, CW; Raymond, KN; Taylor, GN; White, D | 1 |
| Duffield, JR; Proctor, SA; Taylor, DM | 1 |
| Chimiak, A; Przychodzen, W; Rochalska, M; Szot, Z; Wojewódzka, M | 1 |
| Ruemmler, PS; Sullivan, MF | 1 |
| Durbin, PW; Masse, R; Metivier, H; Raymond, KN | 1 |
| Jones, CW; Lloyd, CR; Lloyd, RD; Mays, CW; Taylor, GN; Wrenn, ME | 1 |
| Liubchanskiĭ, ER; Loshchilova, IG; Plotnikova, LA | 1 |
| Brammer, TW; Burnham, JW; Jones, CW; Lloyd, RD; Mays, CW | 1 |
| Hodgson, A; Moody, JC; Stather, JW; Stradling, GN; Sumner, SA | 1 |
| Beliaev, IK; Il'in, LA; Ivannikov, AT; Smirnov, AA | 1 |
| Gray, SA; Hodgson, A; Moody, J; Stather, JW; Stradling, GN | 1 |
| Seidel, A; Volf, V | 2 |
| Brown, H; Chladek, DL; Lindenbaum, A; Moretti, ES; Rosenthal, MW; Russell, JJ | 1 |
| Bair, WJ; Thompson, RC | 1 |
| Jolly, L; McClearen, HA; Poda, GA; Walke, WP | 1 |
| Cerny, EA; Rahman, YE; Rosenthal, MW | 1 |
| Lafuma, J; Morin, M; Nenot, JC | 2 |
| Lafuma, J; Morin, M; Nenot, JC; Skupinski, W | 1 |
| Lynn, JC; Schofield, GB | 1 |
| Baxter, DW; Lindenbaum, A; Rosenthal, MW | 1 |
| Meier, DM; Sanders, CL | 1 |
| Popplewell, DS | 1 |
| Ohlenschläger, L; Schieferdecker, H | 1 |
| Dolphin, GW; Howells, H; Lynn, JC; Schofield, GB; Ward, F | 1 |
| Dilley, JV | 2 |
| Valentin, N | 1 |
| Boss, MR; Mann, JR | 1 |
| Ballou, JE; Hess, JO | 1 |
| Norwood, WD | 1 |
| Taylor, DM | 2 |
| Lafuma, J; Masse, R; Morin, M; Nenot, JC | 1 |
| Joshima, H; Kashima, M; Matsuoka, O; Noda, Y | 1 |
| Smith, VH | 2 |
| Baxter, DW; Sullivan, MF | 1 |
| Andersen, BV; Heid, KR; Jech, JJ | 1 |
| Lebel, JL; Watters, RL | 1 |
| McClellan, RO | 1 |
| Bistline, RW; Lebel, JL; Watters, RL | 1 |
| Andersen, BV; Bramson, PE; Jech, JJ | 1 |
| Hammond, SE; Hyltron, DB; Lagerquist, CR | 1 |
| James, AC; Taylor, DM | 1 |
| Beliaev, IuA; Bukhtoiarova, EM; Erokhin, RA; Lemberg, VK | 1 |
| Sanders, CL | 1 |
| McClanahan, BJ; Ragan, HA | 1 |
| Dilley, JV; McDonald, KE | 1 |
| Brown, H; Lindenbaum, A; Lund, CJ; Moretti, ES; Rosenthal, MW; Russell, JJ; Smoler, MH | 1 |
| Lindenbaum, A; Moretti, ES; Rosenthal, MW; Russell, JJ | 2 |
| Bair, WJ; Sanders, CL | 2 |
| McClanahan, BJ | 1 |
| Lindenbaum, A; Rosenthal, MW; Smoler, HM | 1 |
| Koshurnikova, NA; Liubchanskii, ER | 2 |
| Bull, EH; Johnson, LJ; Lebel, JL; Watters, RL | 1 |
| Hammond, SE; Johnson, LJ; Lagerquist, CR; Watters, RL | 1 |
| Chapman, IV; Marlow, CG; Smith, H | 1 |
| Hammond, SE; Lagerquist, CR; Piltingsrud, CW; Putzier, EA | 1 |
| Ballou, JE; Palotay, JL | 1 |
| Boudène, C; Lutz, M; Métivier, H; Truhaut, R | 1 |
| Lindenbaum, A; Osenthal, MW | 1 |
| Lagerquist, CR; Piltingsrud, CW; Putzier, EA | 1 |
| Bulman, RA; Griffin, RJ | 2 |
| Duffield, JR; May, PM; Williams, DR | 1 |
| Peter, E; Volf, V | 1 |
| Ham, SE; Lennox, AM; Stather, JW; Stradling, GN; Strong, JC; Sumner, SA | 1 |
| Blank, ML; Byrd, BL; Cress, EA; Snyder, F; Washburn, LC | 1 |
| Bazhin, AG; Liubchanskiĭ, ER; Nifatov, AN; Siniakov, EG | 1 |
| Lafuma, J; Masse, R; Metivier, H | 1 |
| Cooper, JR; Ham, SE; Stather, JW; Stradling, GN; Sumner, SA | 1 |
| Gorham, LS; Miller, BM; Sullivan, MF | 1 |
| Bulman, RA; Ellender, M; Ham, S; Hodgson, A; James, AC; Payne, S; Smith, H; Stather, JW; Stradling, GN; Strong, JC; Sumner, S; Towndrow, C | 1 |
| Lafuma, J; Masse, R; Metivier, H; Rateau, G | 1 |
| Rodwell, P; Stather, JW | 1 |
| Ham, SE; Stather, JW; Stradling, GN; Sumner, SA | 1 |
| Taylor, DM; Volf, V | 1 |
| Humphreys, ER; Stones, VA | 1 |
| Levdik, TI; Osobets, SV | 1 |
| Jones, CW; Lloyd, RD; Mays, CW | 1 |
| Guilmette, RA; Muggenburg, BA | 1 |
| Burgada, R; Durbin, PW; Raymond, KN; Volf, V | 1 |
| Ellender, M; Gray, SA; Hodgson, A; Moody, JC; Pearce, M; Stradling, GN; Wilson, I | 1 |
| Bailly, T; Burgada, R; Durbin, PW; Gray, SA; Leroux, Y; Moody, JC; Pearce, MJ; Raymond, KN; Stradling, GN; Wilson, I | 1 |
| Bailly, T; Burgada, R; Durbin, PW; Fritsch, P; Grillon, G; Metivier, H; Paquet, F; Poncy, JL; Raymond, KN | 1 |
| Gray, SA; Hodgson, A; Isaacs, KR; Pearce, MJ; Stradling, GN; Wilson, I | 1 |
| Durbin, PW; Kullgren, B; Schmidt, CT | 1 |
| Cazoulat, A; Ducousso, R; Gerasimo, P; Jourdain, D; Laroche, P; Schoulz, D | 1 |
| Bailly, T; Burgada, R; Cazoulat, A; Gerasimo, P | 1 |
| Luz, A; Müller, WA; Rencová, J; Schäffer, E; Volf, V | 1 |
| Gerasimo, P; Hoffschir, D; Marty, JP; Tymen, H | 1 |
| Durbin, PW; Ebbe, SN; Kullgren, B; Raymond, KN; Uhlir, LC; Xu, J | 1 |
| Attrep, M; Hossner, LR; Kung, KS; Lee, JH | 1 |
| DUNCAN, KP | 1 |
| LINDENBAUM, A; MARKLEY, JF; ROSENTHAL, MW | 3 |
| BAISOGOLOV, GD; PLOTNIKOVA, LA | 1 |
| BATES, TH; CHAPMAN, IV; DYMOND, B; SMITH, H | 1 |
| TOMBROPOULOS, EG | 1 |
| Belyaev, AP; Khokhryakov, VF; Kudryavtseva, TI; Moroz, GS; Schadilov, AE; Shalaginov, VA | 1 |
| Bailey, BR; Eckerman, KF; Townsend, LW | 1 |
| Durbin, PW; Guilmette, RA; Hakimi, R; Raymond, KN; Xu, J | 1 |
| Bailly, T; Burgada, R; Fritsch, P; Grillon, G; Ramounet-Le Gall, B; Rateau, G | 1 |
| Benech, H; Deverre, JR; Fanet, M; Fattal, E; Fritsch, P; Manceau, J; Phan, G; Ramounet-Le Gall, B | 1 |
| Bérard, P; Courtay, C; Grappin, L; Joussineau, S; List, V; Ménétrier, F; Morcillo, MA; Raynaud, P; Rencova, J; Stradling, GN; Taylor, DM; Wood, R | 1 |
| Blinov, AP; Gasteva, GN; Krasniuk, VI; Kuz'menko, LG | 1 |
| Benech, H; Cholet, S; Deverre, JR; Fattal, E; Herbet, A; Phan, G | 1 |
| Fukuda, S | 1 |
| Bruenger, FW; Liu, G; Lloyd, RD; Miller, SC | 1 |
| Benech, H; Deverre, JR; Fattal, E; Fouillit, M; Grillon, G; Le Gall, B; Phan, G; Rouit, E | 1 |
| Bénech, H; Deverre, JR; Fattal, E; Le Gall, B; Phan, G | 1 |
| Benech, H; Deverre, JR; Fattal, E; Fritsch, P; Geiger, S; Gervelas, C; Grillon, G; Le Gall, B; Serandour, AL; Taulelle, C; Tsapis, N | 1 |
| Hodgson, SA; Stradling, N; Taylor, DM | 1 |
| Fottorino, R; Fritsch, P; Grappin, L; Guillermin, AM; Mièle, A; Ruffin, M | 1 |
| Bénech, H; Deverre, JR; Fattal, E; Fréchou, M; Fritsch, P; Gervelas, C; Grillon, G; Poncy, JL; Sérandour, AL; Tsapis, N | 1 |
| Aggarwal, SK; Hegde, AG; Rao, DD; Yadav, JR | 1 |
| Carbaugh, EH; Glover, SE; James, AC; Sasser, LB; Stuit, DB | 1 |
| Jin, Y | 1 |
| Fréchou, M; Fritsch, P; Grémy, O; Poncy, JL; Renault, D; Sérandour, AL | 1 |
| Durbin, PW | 1 |
| Berard, P; Blanchardon, E; Breustedt, B; Fritsch, P; Giussani, A; Lopez, MA; Luciani, A; Nosske, D; Piechowski, J; Schimmelpfeng, J; Sérandour, AL | 2 |
| Abram, MC; Benech, H; Deverre, JR; Fattal, E; Fritsch, P; Grémy, O; Phan, G; Poncy, JL; Renault, D; Sérandour, AL; Tsapis, N | 1 |
| Bowman, BM; Miller, SC; Wang, X | 1 |
| Addleman, RS; Creim, JA; Fryxell, GE; Pattamakomsan, K; Sangvanich, T; Timchalk, C; Wiacek, RJ; Yantasee, W | 1 |
| Abram, MC; Chau, Q; Grémy, O; Renault, D; Tsapis, N; Van der Meeren, A | 1 |
| Antonio, CL; Carbaugh, EH; Lynch, TP; Medina-Del Valle, F | 1 |
| Bertelli, L; Eaton, MC; Gadd, MS; Guilmette, RA; Miller, G; Waters, TL | 1 |
| Benech, H; Deverre, JR; Fattal, E; Fritsch, P; Grémy, O; Phan, G; Poncy, JL; Sérandour, AL; Tsapis, N | 1 |
| Belosokhov, MV; Levina, ES; Schadilov, AE | 1 |
| Balásházy, I; Bérard, P; Blanchardon, E; Breustedt, B; Broggio, D; Castellani, CM; Franck, D; Giussani, A; Hurtgen, C; James, AC; Klein, W; Kramer, GH; Li, WB; Lopez, MA; Malatova, I; Marsh, JW; Nosske, D; Oeh, U; Pan, G; Peixoto Telles, P; Puncher, M; Schimmelpfeng, J; Teixoto Telles, P; Vrba, T | 1 |
| Abe, T | 1 |
| Heyl, A; Kazzi, ZN; Ruprecht, J | 1 |
| Fjeld, RA; Kaplan, DI; Molz, FJ; Thompson, SW | 1 |
| Brown, MA; Gelis, AV; Paulenova, A | 1 |
| Bruel, S; Grémy, O; Renault, D; Tsapis, N; Van der Meeren, A | 1 |
| Coudert, S; Griffiths, NM; Renault, D; Van der Meeren, A; Wilk, JC | 1 |
| BAIR, WJ; TOMBROPOULOS, EG | 1 |
| BUSTAD, LK; CABLE, JW; HORSTMAN, VG; MCCLANAHAN, BJ; WOOD, DH | 1 |
| BALLOU, JE | 1 |
| BAIR, WJ; BRECKINRIDGE, CE; MCDONALD, KE; TOMBROPOULOS, EG | 1 |
| Angulo, JF; Coudert, S; Griffiths, NM; Renault, D; Van der Meeren, A; Wilk, JC | 1 |
| Blanchardon, E; Breustedt, B; Fritsch, P; Giussani, A; Hoeschen, C; Kastl, M; Lopez, MA | 1 |
| Brey, R; Konzen, K | 1 |
| Bérard, P; Fritsch, P; Leprince, B; Roméo, PH | 1 |
| Brey, R; Konzen, K; Miller, S | 1 |
| Blanchardon, E; Bohand, S; Correze, P; Davesne, E; Franck, D; Peleau, B | 1 |
| Coudert, S; Grémy, O; Griffiths, NM; Laurent, D; Miccoli, L | 1 |
| Fulzele, DP; Kaushik, CP; Singh, S | 1 |
| Angulo, JF; Laroche, P; Laurent, D; Moureau, A; Van der Meeren, A | 1 |
| Abend, M; Eder, S; Lamkowski, A; Port, M; Rump, A; Stricklin, D | 1 |
| Bertelli, L; Klumpp, JA; Poudel, D; Waters, TL | 1 |
| Coudert, S; Grémy, O; Miccoli, L; Renault, D | 1 |
| Avtandilashvili, M; Dumit, S; Tolmachev, SY | 1 |
| Guilmette, RA; Klumpp, JA; Melo, D; Miller, G; Poudel, D | 1 |
| Bohand, S; Cherel, M; Grémy, O; Lelan, F; Miccoli, L; Mougin-Degraef, M | 1 |
| Dainiak, N; Findley, WM; Sugarman, SL; Toohey, RE | 1 |
| Abergel, RJ; Chen, S; Ko, R; Lai, EPC; Li, C; Wyatt, H | 1 |
| Akashi, M; Kim, E; Kurihara, O; Momose, T; Sagara, M; Takada, C; Tatsuzaki, H; Tominaga, T; Tsutsumi, Y; Watanabe, S | 1 |
| Avtandilashvili, M; Dumit, S; McComish, SL; Strom, DJ; Tabatadze, G; Tolmachev, SY | 2 |
| Angulo, JF; Bohand, S; Griffiths, NM; Van der Meeren, A | 1 |
| Grémy, O; Laroche, P; Ménétrier, F; Miccoli, L | 1 |
| Gremy, O; Miccoli, L | 1 |
| Avtandilashvili, M; Breustedt, B; Dumit, S; McComish, SL; Strom, DJ; Tabatadze, G; Tolmachev, SY | 1 |
| Goans, RE | 1 |
| Berdal, M; Devilliers, K; Grémy, O; Laroche, P; Miccoli, L; Mougin-Degraef, M | 1 |
| Bertelli, L; Dumit, S; Klumpp, JA; Miller, G; Poudel, D; Waters, TL | 1 |
| Baglan, N; Coudert, S; Griffiths, NM; Lamart, S; Van der Meeren, A | 1 |
| Avtandilashvili, M; Tolmachev, SY | 1 |
| Blanchin, N; Grémy, O; Miccoli, L | 2 |
| Miller, SC; Sokolova, AB; Suslova, KG | 1 |
| Alshehri, S; Fan, W; Garrison, JC; Zhang, W | 1 |
| Lai, EPC; Li, C | 1 |
| Albanese, J; Dainiak, N | 1 |
| Berthomieu, C; Defrance, M; Griffiths, NM; Moureau, A; Van der Meeren, A | 1 |
| Bertelli, L; Dumit, S; Klumpp, J; Miller, G; Poudel, D | 1 |
| Devilliers, K; Grémy, O; Miccoli, L | 1 |
| Akashi, M; Ishigure, N; Kim, E; Kurihara, O; Tani, K; Tatsuzaki, H; Tominaga, T | 1 |
| Giussani, A; Grémy, O; Hoeschen, C; Kastl, M; Lamart, S; Li, WB | 1 |
7 review(s) available for plutonium and pentetic acid
| Article | Year |
|---|---|
Removal of inhaled radioactive particles by lung lavage--a review.
Topics: Air Pollutants; Air Pollutants, Radioactive; Animals; Cerium Radioisotopes; Dogs; Environmental Exposure; Haplorhini; Humans; Injections, Intravenous; Lung; Papio; Pentetic Acid; Plutonium; Therapeutic Irrigation; Time Factors | 1977 |
Plutonium: biomedical research.
Topics: Aerosols; Animals; Autoradiography; Body Burden; Bone and Bones; Dogs; Dose-Response Relationship, Radiation; Half-Life; Humans; Liver; Lung; Lung Neoplasms; Lymph Nodes; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Osteosarcoma; Pentetic Acid; Plutonium; Pulmonary Fibrosis; Radiation Injuries; Rats | 1974 |
Chelating agents used for plutonium and uranium removal in radiation emergency medicine.
Topics: Animals; Aza Compounds; Catechols; Chelating Agents; Deferiprone; Diphosphonates; Emergency Medicine; Humans; Iron Chelating Agents; Pentetic Acid; Plutonium; Pyridones; Radiation Injuries; Uranium | 2005 |
Biokinetic modelling of DTPA decorporation therapy: the CONRAD approach.
Topics: Chelating Agents; Humans; Kinetics; Models, Biological; Pentetic Acid; Plutonium; Radiation Injuries | 2009 |
Calcium and zinc DTPA administration for internal contamination with plutonium-238 and americium-241.
Topics: Americium; Animals; Chelating Agents; Humans; Molecular Structure; Pentetic Acid; Plutonium; Radiation Injuries | 2012 |
Actinide Decorporation: A Review on Chelation Chemistry and Nanocarriers for Pulmonary Administration.
Topics: Actinoid Series Elements; Chelating Agents; Humans; Lecithins; Liposomes; Pentetic Acid; Plutonium | 2022 |
Assessment and clinical management of internal contamination.
Topics: Americium; Decontamination; Humans; Pentetic Acid; Plutonium; Radioisotopes | 2022 |
1 trial(s) available for plutonium and pentetic acid
| Article | Year |
|---|---|
FDA IND approval for Zn-DTPA, new clinical agent for decorporation therapy of actinides.
Topics: Actinoid Series Elements; Clinical Trials as Topic; Humans; Pentetic Acid; Plutonium; Zinc | 1979 |
241 other study(ies) available for plutonium and pentetic acid
| Article | Year |
|---|---|
Pu and Am decorporation in beagles: effects of magnitude of initial Ca-DTPA injection upon chelation efficacy.
Topics: Adult; Americium; Animals; Calcium; Child; Dogs; Dose-Response Relationship, Drug; Feces; Female; Humans; Male; Pentetic Acid; Plutonium; Pregnancy; Time Factors; Whole-Body Counting | 1979 |
Mixed ligand chelate therapy for plutonium and cadmium poisoning.
Topics: Animals; Cadmium Poisoning; Chelating Agents; Drug Therapy, Combination; Female; Mice; Pentetic Acid; Plutonium; Solubility | 1978 |
FDA IND approval for Zn-DTPA, new clinical agent for decorporation therapy of actinides.
Topics: Actinoid Series Elements; Humans; Pentetic Acid; Plutonium; Research Design; Zinc | 1979 |
Toward an optimal DTPA therapy for decorporation of actinides: time-dose relationships for plutonium in the dog. I.
Topics: Actinoid Series Elements; Animals; Bone and Bones; Connective Tissue; Dogs; Dose-Response Relationship, Drug; Drug Administration Schedule; Male; Pentetic Acid; Plutonium; Radiation Dosage; Radiation Injuries, Experimental; Time Factors | 1979 |
The effect of chemical form on the clearance of 239-plutonium from the respiratory system of the rat.
Topics: Absorption; Adrenal Glands; Animals; Bone and Bones; Citrates; Digestive System; Feces; Hair; Kidney; Liver; Lung; Muscles; Myocardium; Nitrates; Oxalates; Oxides; Pentetic Acid; Plutonium; Rats; Rats, Inbred Strains; Respiratory System; Spleen; Urine | 1975 |
Influence of inhaled Ca-DTPA on the long-term effects of inhaled Pu nitrate.
Topics: Aerosols; Animals; Body Weight; Bone Neoplasms; Calcium; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Lung; Lung Neoplasms; Male; Neoplasms; Neoplasms, Radiation-Induced; Nitrates; Osteosarcoma; Pentetic Acid; Plutonium; Rats | 1977 |
Synthesis and therapeutic testing of mono- and dialkyl esters of pentetic (diethylenetriaminepentaacetic) acid for decorporation of polymeric plutonium.
Topics: Animals; Body Burden; Bone and Bones; Esters; Female; Liver; Mice; Pentetic Acid; Plutonium; Polymers | 1979 |
Experimental studies of the use of DTPA and other agents to limit the systemic burden of plutonium after wound contamination.
Topics: Aminocaproates; Animals; Body Burden; Bufexamac; Cricetinae; Drug Interactions; Female; Hydroxamic Acids; Injections, Intramuscular; Injections, Intravenous; Nicotinic Acids; Pentetic Acid; Plutonium; Rats; Time Factors; Tissue Distribution; Wounds and Injuries | 1979 |
Dependency of chelation efficacy upon time after first DTPA injection.
Topics: Americium; Animals; Body Burden; Bone and Bones; Dogs; Drug Administration Schedule; Female; Humans; Kidney; Liver; Pentetic Acid; Plutonium; Radiation Injuries, Experimental; Spleen; Time Factors | 1979 |
The influence of DTPA on the metabolism of inhaled 239PuF4 in beagles.
Topics: Animals; Autoradiography; Dogs; Feces; Fluorides; Lung; Pentetic Acid; Plutonium; Respiration; Time Factors; Tissue Distribution | 1979 |
[Late sequelae of the inhalational uptake of 239Pu under the influence of Ca- or ZnDTPA therapy].
Topics: Aerosols; Animals; Calcium; Dose-Response Relationship, Radiation; Lung Neoplasms; Male; Neoplasms, Experimental; Pentetic Acid; Plutonium; Radiation Injuries, Experimental; Rats; Time Factors; Zinc | 1979 |
[Microlocalization of 239Pu in structural elements of interalveolar septa after inhalation of different of its compound and pentacin].
Topics: Animals; Male; Pentetic Acid; Plutonium; Pulmonary Alveoli; Rats | 1979 |
Action of DTPA on hepatic plutonium. III. Evidence for a direct chelation mechanism for DTPA-induced excretion of monomeric plutonium into rat bile.
Topics: Animals; Bile; Bile Ducts; Catheterization; Female; Liver; Pentetic Acid; Plutonium; Rats | 1979 |
An examination of some complexing agents for ability to remove intracellularly deposited plutonium.
Topics: Animals; Bone and Bones; Bufexamac; Chelating Agents; Chromones; Cricetinae; Deferoxamine; Female; Glycine; Hydroxamic Acids; Liver; Mesocricetus; Pentetic Acid; Piperazines; Plutonium; Pyridines | 1979 |
The in vivo solubility of plutonium-239 dioxide in the rat lung.
Topics: Aerosols; Animals; Decontamination; Feces; Lung; Male; Particle Size; Pentetic Acid; Plutonium; Rats; Solubility; Tissue Distribution | 1977 |
[Relationship between Pu-239 and various components of the bone tissue and the effect of DTPA on this relationship].
Topics: Animals; Bone and Bones; Collagen; Pentetic Acid; Plutonium; Proteins; Rats; Solubility | 1978 |
Action of DTPA on hepatic plutonium I. Quantitation of the DTPA-induced biliary excretion of plutonium in the rat.
Topics: Animals; Bile; Female; Liver; Pentetic Acid; Plutonium; Rats; Time Factors | 1978 |
Removal of plutonium from beagles using Ca-DTPA and Zn-DTPA: effects on initial DTPA injection.
Topics: Animals; Calcium; Dogs; Female; Male; Pentetic Acid; Plutonium; Radiation Injuries, Experimental; Tissue Distribution; Zinc | 1978 |
Decorporation from beagles of a mixture of monomeric and particulate plutonium using Ca-DTPA and Zn-DTPA: dependence upon frequency of administration.
Topics: Animals; Calcium; Dogs; Female; Male; Pentetic Acid; Plutonium; Radiation Injuries, Experimental; Time Factors; Tissue Distribution; Zinc | 1978 |
A mathematical model for estimation of plutonium in the human body from urine data influenced by DTPA therapy.
Topics: Accidents, Occupational; Body Burden; Environmental Exposure; Humans; Models, Biological; Pentetic Acid; Plutonium; Time Factors; Tissue Distribution | 1978 |
The influence of DTPA on the biological availability of transuranics.
Topics: Americium; Animals; Curium; Ecology; Intestinal Absorption; Male; Pentetic Acid; Plants; Plutonium; Radioisotopes; Rats; Soil; Uranium | 1978 |
Estimation of skeletal plutonium levels based on DPTA-induced radionuclide excretion in feces: possible application to man.
Topics: Americium; Animals; Bone and Bones; Dogs; Drug Administration Schedule; Evaluation Studies as Topic; Feces; Female; Femur; Humans; Liver; Methods; Mice; Papio; Pentetic Acid; Plutonium; Rats; Swine | 1978 |
Action of DTPA on hepatic plutonium. II. DTPA-induced removal of monomeric plutonium from mouse liver parenchymal cells.
Topics: Animals; Female; Liver; Methods; Mice; Pentetic Acid; Plutonium; Time Factors | 1978 |
Efficacy of Zn-DTPA and Ca-DTPA in removing plutonium from the human body.
Topics: Aerosols; Calcium; Humans; Injections, Intravenous; Pentetic Acid; Plutonium; Radiation Injuries; Zinc | 1978 |
Comparative effectiveness of Ca-DTPA, desferrioxamine B and their combination in removing transuranium elements from rats.
Topics: Americium; Animals; Binding Sites; Bone and Bones; Calcium; Californium; Curium; Deferoxamine; Evaluation Studies as Topic; Female; Methods; Pentetic Acid; Plutonium; Rats | 1977 |
Effect of ascorbate ions in DTPA treatment after contamination by mixed plutonium dioxide-sodium burning products.
Topics: Animals; Ascorbic Acid; Female; Ions; Male; Pentetic Acid; Plutonium; Protein Binding; Radiation Injuries, Experimental; Rats; Sodium | 1977 |
DTPA treatment schedules for decorporation of 239Pu from simulated wounds.
Topics: Animals; Calcium; Chelating Agents; Citrates; Female; Nitrates; Pentetic Acid; Plutonium; Rats; Wounds, Penetrating; Zinc | 1977 |
Retention of 241Am and 239Pu in the rat as influenced by triton WR 1339.
Topics: Americium; Animals; Bone and Bones; Decontamination; Drug Combinations; Female; Kidney; Liver; Pentetic Acid; Plutonium; Polyethylene Glycols; Quaternary Ammonium Compounds; Rats | 1976 |
The removal of inhaled 239Pu from beagle dogs by bronchopulmonary lavage and chelation therapy.
Topics: Animals; Bronchi; Decontamination; Dogs; Female; Lung; Male; Pentetic Acid; Plutonium; Therapeutic Irrigation | 1976 |
Some factors influencing the uptake of plutonium-239 by pea plants.
Topics: Colloids; Food Contamination, Radioactive; Pentetic Acid; Plants; Plutonium | 1976 |
[239Pu distribution in bone tissue elements and the effects of DTPA on this process].
Topics: Animals; Bone and Bones; Esters; Femur; Male; Pentetic Acid; Plutonium; Rats; Time Factors | 1976 |
Removal of polymeric plutonium from dogs with DTPA and glucan.
Topics: Animals; Bone and Bones; Decontamination; Dogs; Drug Therapy, Combination; Feces; Female; Kidney; Liver; Lung; Lymph Nodes; Muscles; Ovary; Pentetic Acid; Plutonium; Polysaccharides; Saccharomyces cerevisiae; Spleen | 1975 |
Translocation kinetics of plutonium oxide from the popliteal lymph nodes of beagles.
Topics: Animals; Biological Transport; Decontamination; Dogs; Foot; Hindlimb; Injections, Subcutaneous; Kinetics; Lymph Nodes; Male; Pentetic Acid; Plutonium | 1975 |
Removal of polymeric plutonium by DTPA directed into cells by liposome encapsulation.
Topics: Animals; Bone and Bones; Decontamination; Female; Injections, Intraperitoneal; Injections, Intravenous; Liposomes; Liver; Mice; Pentetic Acid; Plutonium; Splenomegaly | 1975 |
The effect of combination of chelating agents on the translocation of intramuscularly depostied 239Pu nitrate in the rat.
Topics: Animals; Bone and Bones; Chelating Agents; Citrates; Deferoxamine; Drug Synergism; Hyaluronic Acid; Injections, Intramuscular; Kidney; Lactates; Liver; Male; Mepivacaine; Nitrates; Pentetic Acid; Picolinic Acids; Plutonium; Pyruvates; Rats; Tartrates; Time Factors | 1975 |
Removal of inhaled 239PuO2 from beagle dogs by pulmonary lavage.
Topics: Animals; Decontamination; Dogs; Lung; Pentetic Acid; Plutonium; Therapeutic Irrigation | 1975 |
Efficacy of Zn-DTPA in removing plutonium from the human body.
Topics: Adult; Calcium; Decontamination; Humans; Pentetic Acid; Plutonium; Zinc | 1976 |
Importance of initial management of persons internally contaminated with radionuclides.
Topics: Cathartics; Chelating Agents; Humans; Iodine; Iodine Radioisotopes; Isotopes; Pentetic Acid; Plutonium; Radiation Injuries; Radioisotopes; Time Factors | 1976 |
The efficacies of 3,4,3-LIHOPO and DTPA for enhancing the excretion of plutonium and americium from the rat: comparison with other siderophore analogues.
Topics: Administration, Inhalation; Americium; Amides; Animals; Aza Compounds; Body Burden; Female; Injections, Intravenous; Kidney; Liver; Pentetic Acid; Plutonium; Pyridones; Rats | 1992 |
The efficacy of DFO-HOPO, DTPA-DX and DTPA for enhancing the excretion of plutonium and ameriicum from the rat.
Topics: Administration, Inhalation; Americium; Animals; Chelating Agents; Decontamination; Deferoxamine; Female; Hydroxamic Acids; Injections, Intravenous; Pentetic Acid; Plutonium; Pyridones; Rats | 1991 |
Effectiveness of DTPA treatments following the injection of particulate plutonium.
Topics: Animals; Bone and Bones; Bone Neoplasms; Dogs; Injections, Intravenous; Liver; Neoplasms, Radiation-Induced; Pentetic Acid; Plutonium; Spleen | 1991 |
[Effects of pentacin on subcellular distribution of Pu-239 nitrate in the lungs of rats].
Topics: Animals; Citrates; Lung; Male; Organelles; Pentetic Acid; Plutonium; Rats; Rats, Inbred Strains; Subcellular Fractions | 1991 |
[238Pu body distribution in dogs after intravenous administration and early complexon therapy].
Topics: Animals; Chelating Agents; Citrates; Dogs; Drug Evaluation, Preclinical; Female; Injections, Intravenous; Male; Organic Chemicals; Organometallic Compounds; Pentetic Acid; Plutonium; Radiation Injuries, Experimental; Time Factors; Tissue Distribution | 1990 |
Efficacy and toxicity of N,N',N",N"'-tetra(2,3,4-trihydroxybenzoyl)-spermine for decorporation of 239Pu from mice.
Topics: Animals; Bone and Bones; Chelating Agents; Kidney; Liver; Male; Mice; Pentetic Acid; Plutonium; Spermidine; Spermine | 1989 |
Testing of methyleneiminodiacetic-catechol and other aromatic chelating agents for decorporation of 238Pu and 241Am in rats.
Topics: Americium; Animals; Chelating Agents; Female; Isoquinolines; Pentetic Acid; Plutonium; Rats; Rats, Inbred Strains; Spermidine; Tissue Distribution | 1989 |
The efficacies of pure LICAM(C) and DTPA on the retention of plutonium-238 and americium-241 in rats after their inhalation as nitrate and intravenous injection as citrate.
Topics: Aerosols; Americium; Animals; Chelating Agents; Chromatography, High Pressure Liquid; Female; Hydrogen-Ion Concentration; Injections, Intravenous; Methylation; Nitrates; Pentetic Acid; Plutonium; Rats; Spermidine; Structure-Activity Relationship; Tissue Distribution | 1989 |
The efficacies of pure LICAM(C) and DTPA for enhancing the elimination of plutonium-238 and americium-241 from rats after their inhalation as nitrate.
Topics: Administration, Inhalation; Americium; Animals; Chelating Agents; Female; Nitrates; Pentetic Acid; Plutonium; Rats; Spermidine | 1989 |
[Reduction in the level of 239Pu in pulmonary tissue using octacin].
Topics: Animals; Chelating Agents; Decontamination; Female; Lung; Organic Chemicals; Pentetic Acid; Plutonium; Rats; Rats, Inbred Strains | 1989 |
Essential trace metal concentrations in beagle liver and bone tissue after prolonged Zn-DTPA treatment.
Topics: Americium; Animals; Bone and Bones; Chelating Agents; Decontamination; Dogs; Female; Liver; Male; Pentetic Acid; Plutonium; Trace Elements; Zinc | 1989 |
[Biological effects of the intramuscular administration of 239Pu as affected by chelate therapy].
Topics: Animals; Female; Injections, Intramuscular; Male; Neoplasms, Radiation-Induced; Pentetic Acid; Plutonium; Rats | 1988 |
[Biological action of 239Pu during intake by inhalation and complexon therapy with Zn or Ca DTPA under experimental conditions].
Topics: Administration, Inhalation; Animals; Decontamination; Lung Neoplasms; Male; Neoplasms, Radiation-Induced; Nitrates; Pentetic Acid; Plutonium; Pulmonary Fibrosis; Rats; Rats, Inbred Strains | 1988 |
[Value of standard Licam (C) in plutonium radiocontamination].
Topics: Animals; Drug Therapy, Combination; Male; Papio; Pentetic Acid; Plutonium; Radiation Injuries, Experimental; Rats; Rats, Inbred Strains; Spermidine | 1987 |
Chelation therapy of incorporated plutonium-238 and americium-241: comparison of LICAM(C), DTPA and DFOA in rats, hamsters and mice.
Topics: Americium; Animals; Bone and Bones; Chelating Agents; Cricetinae; Deferoxamine; Kidney; Kinetics; Liver; Mice; Pentetic Acid; Plutonium; Rats; Spermidine; Time Factors; Tissue Distribution | 1986 |
Efficacies of LICAM(C) and DTPA for the decorporation of inhaled transportable forms of plutonium and americium from the rat.
Topics: Aerosols; Americium; Animals; Bone and Bones; Chelating Agents; Citrates; Cricetinae; Female; Injections, Intravenous; Kidney; Liver; Lung; Male; Mice; Organometallic Compounds; Organophosphates; Pentetic Acid; Plutonium; Rats; Spermidine | 1986 |
Studies on the metabolic behaviour of industrial actinide-bearing aerosols after deposition in the rat lung: an experimental basis for interpreting chest monitoring data and assessing limits on intake for workers.
Topics: Aerosols; Air Pollutants; Air Pollutants, Occupational; Air Pollutants, Radioactive; Americium; Animals; Environmental Exposure; Female; Half-Life; Humans; Lung; Maximum Allowable Concentration; Metabolic Clearance Rate; Pentetic Acid; Plutonium; Rats; Tissue Distribution | 1987 |
Reducing the cancer risk of 239Pu by chelation therapy.
Topics: Animals; Bone Neoplasms; Chelating Agents; Dogs; Dose-Response Relationship, Drug; Female; Mice; Mice, Inbred BALB C; Neoplasms, Radiation-Induced; Pentetic Acid; Plutonium; Risk; Sarcoma, Experimental; Time Factors | 1986 |
Decorporation of Pu and Am from beagles with delayed daily injections of 3,4,3-LICAM(C) or Zn-DTPA.
Topics: Americium; Animals; Decontamination; Dogs; Female; Male; Pentetic Acid; Plutonium; Spermidine; Time Factors | 1986 |
The binding of plutonium to transferrin in the presence of tri-n-butyl phosphate or nitrate and its release by diethylenetriaminepenta-acetate and the tetrameric catechoylamide ligand LICAMC(C).
Topics: Animals; Chelating Agents; Humans; In Vitro Techniques; Nitrates; Organophosphates; Pentetic Acid; Plutonium; Protein Binding; Rats; Spermidine; Transferrin | 1986 |
Removal of 239Pu from mice with 3,4,3 LICAM(C) or N,N',N'',N'''-tetra-(2,3-dihydroxybenzoyl)-spermine.
Topics: Animals; Bone and Bones; Chelating Agents; Femur; Kidney; Kinetics; Liver; Male; Mice; Mice, Inbred Strains; Pentetic Acid; Plutonium; Spermidine; Spermine; Structure-Activity Relationship; Tissue Distribution | 1986 |
Effectiveness of DTPA therapy when administered intragastrically or intraperitoneally to remove Pu from adult or neonatal rats.
Topics: Absorption; Animals; Animals, Newborn; Female; Hydrogen-Ion Concentration; Injections, Intraperitoneal; Pentetic Acid; Plutonium; Radiation Injuries, Experimental; Rats; Stomach | 1986 |
Promotion by tetrameric catechoylamide ligands and CaNa3-DTPA of the dissociation in vitro of the Pu-transferrin complex formed after intravenous injection of Pu-tri-N-butylphosphate.
Topics: Animals; Decontamination; Female; Male; Organometallic Compounds; Organophosphates; Organophosphorus Compounds; Papio; Pentetic Acid; Plutonium; Spermidine; Transferrin | 1985 |
Effect of age on the efficacy of Zn-diethylenetriaminepentaacetic acid therapy for removal of Am and Pu from beagles.
Topics: Aging; Americium; Animals; Decontamination; Dogs; Female; Liver; Male; Pentetic Acid; Plutonium; Zinc | 1985 |
[Characteristics of natural and pentacin-stimulated urinary excretion of 238Pu and 239Pu].
Topics: Animals; Injections, Intraperitoneal; Injections, Intravenous; Kinetics; Male; Pentetic Acid; Plutonium; Rats; Rats, Inbred Strains | 1985 |
Effect of Zn-DTPA therapy on the maternal transfer of 241Am or 237Pu to young mice.
Topics: Americium; Animals; Decontamination; Female; Maternal-Fetal Exchange; Mice; Pentetic Acid; Plutonium; Pregnancy | 1985 |
The metabolism and decorporation of Pu after inhalation of the tributyl phosphate complex by the rat.
Topics: Aerosols; Animals; Decontamination; Female; Lung; Organometallic Compounds; Organophosphates; Organophosphorus Compounds; Pentetic Acid; Plutonium; Rats; Tissue Distribution | 1985 |
[Removal of monomeric 239Pu from bones and liver by liposome-encapsulated pentacin].
Topics: Animals; Bone and Bones; Decontamination; Liposomes; Liver; Male; Pentetic Acid; Plutonium; Rats | 1985 |
Use of DTPA for increasing the rate of elimination of plutonium-238 and americium-241 from rodents after their inhalation as the nitrates.
Topics: Aerosols; Americium; Animals; Cricetinae; Female; Injections, Intraperitoneal; Kinetics; Male; Mesocricetus; Nitrates; Pentetic Acid; Plutonium; Rats; Time Factors; Tissue Distribution | 1985 |
Decorporation of 239Pu and 241Am in the rat and hamster by Zn-DTPA.
Topics: Americium; Animals; Bone and Bones; Cricetinae; Decontamination; Female; Kidney; Liver; Pentetic Acid; Plutonium; Rats; Zinc | 1974 |
Combined effect of DTPA and citrate on an intramuscular 239Pu deposit in rats.
Topics: Animals; Citrates; Decontamination; Drug Therapy, Combination; Male; Muscles; Pentetic Acid; Plutonium; Radiation Injuries, Experimental; Rats | 1974 |
Experimental background for prompt treatment with DTPA of 239Pu-contaminated wounds.
Topics: Animals; Bone and Bones; Decontamination; Dose-Response Relationship, Drug; Injections, Intramuscular; Injections, Intravenous; Liver; Male; Pentetic Acid; Plutonium; Rats; Wounds and Injuries | 1974 |
Removal of plutonium from mouse liver by glucan and DTPA.
Topics: Animals; Bone and Bones; Chelating Agents; Feces; Female; Femur; Glucose; Injections, Intravenous; Liver; Mice; Pentetic Acid; Plutonium; Polysaccharides; Saccharomyces cerevisiae; Time Factors | 1973 |
Treatment and evaluation of a plutonium-238 nitrate contaminated puncture wound. A two-year case history.
Topics: Adult; Aerosols; Body Burden; Debridement; Feces; Finger Injuries; Humans; Injections, Intravenous; Male; Nitrates; Occupational Diseases; Pentetic Acid; Plutonium; Radiation Injuries; Radiation Monitoring; Respiratory Therapy; Skin; Time Factors; Tourniquets; Whole-Body Counting | 1972 |
Intracellular plutonium: removal by liposome-encapsulated chelating agent.
Topics: Animals; Carbon Isotopes; Edetic Acid; Feces; Female; Liposomes; Liver; Mice; Pentetic Acid; Plutonium; Poisoning | 1973 |
Metabolic and therapeutic study following administration to rats of 238 Pu nitrate--a comparison with 239 Pu.
Topics: Aerosols; Animals; Body Burden; Bone and Bones; Feces; Injections, Intramuscular; Liver; Lung; Male; Muscles; Nitrates; Pentetic Acid; Plutonium; Rats | 1972 |
Experimental removal of 144 Ce, 241 Am, 242 Cm and 238 Pu from the rat skeleton.
Topics: Aerosols; Americium; Animals; Bone and Bones; Cerium; Chemical Phenomena; Chemistry; Curium; Feces; Injections, Intramuscular; Liver; Male; Pentetic Acid; Plutonium; Radiation Injuries; Radiometry; Rats; Rats, Inbred Strains; Time Factors | 1972 |
A measure of the effectiveness of DTPA chelation therapy in cases of plutonium inhalation and plutonium wounds.
Topics: Aerosols; Creatinine; Feces; Humans; Mathematics; Mucus; Nitrates; Oxides; Pentetic Acid; Plutonium; Radiation Injuries; Time Factors; Uranium | 1973 |
Decorporation of monomeric plutonium from the dog by glucan and-or DTPA.
Topics: Animals; Bone and Bones; Bone Marrow; Decontamination; Dogs; Kidney; Liver; Lung; Lymph Nodes; Male; Mandible; Muscles; Pentetic Acid; Plutonium; Polysaccharides; Saccharomyces; Spleen; Testis; Tooth | 1973 |
Effects of DTPA on excretion and tissue distribution of injected 238Pu in fed and fasting rats.
Topics: Animals; Bone and Bones; Decontamination; Digestive System; Fasting; Feces; Female; Liver; Pentetic Acid; Plutonium; Rats | 1973 |
Plutonium uptake by cell cultures in presence of some chelating agents.
Topics: Acetone; Ascorbic Acid; Cell Line; Chelating Agents; Chondroitin; Citrates; Deferoxamine; HeLa Cells; Humans; Iron Radioisotopes; Liver; Pentetic Acid; Plutonium; Sodium | 1973 |
[Report on a plutonium-239 contaminated lacerated and incised wound].
Topics: Body Burden; Debridement; Feces; Humans; Injections, Intravenous; Male; Pentetic Acid; Plutonium; Radiation Dosage; Radiation Injuries; Wrist Injuries | 1973 |
Assessment and management of a plutonium contaminated wound case.
Topics: Body Burden; Chromosome Aberrations; Decontamination; Hand Injuries; Humans; Male; Pentetic Acid; Plutonium; Radiation Injuries | 1974 |
In vivo and in vitro chelation of plutonium by alpha-lipoic acid and DTPA. BNWL-714.
Topics: Animals; In Vitro Techniques; Pentetic Acid; Plutonium; Radiation Injuries, Experimental; Rats; Thioctic Acid | 1968 |
The influence of EDTA and DTPA present in urine samples on the alkaline phosphate precipitation.
Topics: Chelating Agents; Chemistry Techniques, Analytical; Edetic Acid; Humans; Pentetic Acid; Plutonium | 1966 |
Body counter evaluations of plutonium exposures.
Topics: Accidents, Occupational; Americium; Blast Injuries; Body Weight; Decontamination; Edetic Acid; Hand; Humans; Liver; Lung; Pentetic Acid; Plutonium; Radiation Injuries; Radiometry; Skull; Spectrum Analysis | 1967 |
Biliary plutonium excretion in the rat.
Topics: Animals; Bile; Cecum; Duodenum; Female; Ileum; Intestinal Absorption; Intestinal Mucosa; Intestines; Jejunum; Methods; Pentetic Acid; Perfusion; Plutonium; Rats; Rats, Inbred Strains | 1972 |
Plutonium ( 239 Pu) toxicity diagnosis and therapy.
Topics: Accidents, Occupational; Animals; Chemical Phenomena; Chemistry; Dogs; Environmental Exposure; Feces; Half-Life; Humans; Intestinal Absorption; Lung; Mice; Neoplasms; Nuclear Energy; Pentetic Acid; Plutonium; Rabbits; Radiation Injuries; Radiation Monitoring; Rats; Registries; Respiration; Respiratory Therapy; Skin Absorption; Time Factors; Wound Infection | 1972 |
Interactions between transuranium elements and the components of cells and tissues.
Topics: Americium; Animals; Blood Proteins; Bone Marrow; Cattle; Centrifugation, Density Gradient; Chromatography, Gel; Curium; Hemosiderin; Humans; Hydrogen-Ion Concentration; Hydrolysis; Liver; Lysosomes; Pentetic Acid; Plutonium; Protein Binding; Rats; Spleen | 1972 |
An experimental comparative study of the behaviour of 237 Np, 238 Pu, 239 Pu, 241 Am and 242 Cm in bone.
Topics: Aerosols; Americium; Animals; Autoradiography; Bone and Bones; Curium; Injections, Intramuscular; Lung; Neptunium; Pentetic Acid; Plutonium; Radiometry; Rats; Rats, Inbred Strains; Time Factors | 1972 |
Whole-body autoradiographic studies on plutonium metabolism as affected by its physico-chemical state and route of administration.
Topics: Aerosols; Animals; Autoradiography; Bone and Bones; Bone Marrow; Chemical Phenomena; Chemistry; Gold Colloid, Radioactive; Injections, Intraperitoneal; Injections, Intravenous; Injections, Subcutaneous; Lethal Dose 50; Liver; Male; Metabolic Clearance Rate; Mice; Nitrates; Particle Size; Pentetic Acid; Phosphorus Isotopes; Plutonium; Polymers; Radiation Effects; Spleen | 1972 |
Therapeutic removal of internally deposited transuranium elements.
Topics: Aerosols; Americium; Animals; Berkelium; Californium; Chelating Agents; Curium; Einsteinium; Half-Life; Neptunium; Pentetic Acid; Plutonium; Radiation Injuries; Radiochemistry; Radioisotopes; Rats | 1972 |
Removal of internally deposited transuranium elements by Zn-DTPA.
Topics: Americium; Animals; Bone and Bones; Calcium; Curium; Female; Liver; Lung; Pentetic Acid; Plutonium; Radiation Injuries; Radiation Injuries, Experimental; Radiometry; Rats; Rats, Inbred Strains; Time Factors; Zinc | 1972 |
Gastrointestinal absorption and retention of plutonium chelates.
Topics: Animals; Citrates; Female; Femur; Gastric Lavage; Intestinal Absorption; Liver; Nitrates; Pentetic Acid; Plutonium; Rats | 1972 |
Interpretation of human urinary excretion of plutonium for cases treated with DTPA.
Topics: Aerosols; Humans; Nitrates; Oxides; Pentetic Acid; Plutonium; Radiation Injuries; Time Factors | 1972 |
Progress in the beagle studies at Colorado State University.
Topics: Aerosols; Americium; Animals; Biological Transport; Dogs; Femur; Liver; Lymph Nodes; Nitrates; Oxides; Pentetic Acid; Plutonium; Radiation Injuries, Experimental; Time Factors | 1972 |
Progress in studies with transuranic elements at the Lovelace Foundation.
Topics: Aerosols; Americium; Animals; Autoradiography; Californium; Cricetinae; Curium; Dogs; Dose-Response Relationship, Radiation; Liver; Mice; Particle Size; Pentetic Acid; Plutonium; Radiation Dosage; Radiation Injuries; Rats; Species Specificity; Time Factors | 1972 |
A study of translocation dynamics of plutonium and americium from simulated puncture wounds in beagle dogs.
Topics: Americium; Animals; Biological Transport; Dogs; Lymph Nodes; Metacarpus; Nitrates; Oxides; Pentetic Acid; Plutonium; Radiation Injuries, Experimental; Time Factors | 1972 |
Comparison of manual and computer evaluation of systemic plutonium burden.
Topics: Aerosols; Body Burden; Computers; Environmental Exposure; Evaluation Studies as Topic; Humans; Pentetic Acid; Plutonium; Radiation Dosage; Radiation Injuries; Time Factors | 1972 |
Distribution of plutonium and americium in the body 5 years after an exposure via contaminated punctured wound.
Topics: Americium; Autopsy; Body Burden; Bone and Bones; Humans; Liver; Male; Middle Aged; Pentetic Acid; Plutonium; Radiation Injuries | 1972 |
DTPA therapy for chelation of 239 Pu in bone: the influence of bone remodelling.
Topics: Alpha Particles; Animals; Autoradiography; Bone and Bones; Bone Neoplasms; Bone Resorption; Epiphyses; Femur; Male; Neoplasms, Radiation-Induced; Osteoblasts; Pentetic Acid; Plutonium; Rats | 1971 |
[Tumors in rats that have received pentacin after the administration of plutonium-239].
Topics: Animals; Bone Neoplasms; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Osteosarcoma; Pentetic Acid; Plutonium; Rats | 1968 |
Phagocytosis of 239-PuO2 particles. BNWL-480.
Topics: Animals; Charcoal; Female; Injections, Intraperitoneal; Macrophages; Pentetic Acid; Phagocytosis; Plutonium; Rats | 1966 |
Translocation of subcutaneously deposited plutonium. BNWL-280.
Topics: Animals; Dimethyl Sulfoxide; Injections, Subcutaneous; Pentetic Acid; Plutonium; Swine | 1966 |
Removal of inhaled 239PuF4 in beagles. BNWL-714.
Topics: Aerosols; Animals; Dogs; Fluorides; Lung; Pentetic Acid; Plutonium; Radiation Injuries, Experimental | 1968 |
Metabolic and therapeutic studies of plutonium. IV. ANL-7535.
Topics: Animals; Autoradiography; Bone and Bones; Chelating Agents; Liver; Mice; Microscopy, Electron; Pentetic Acid; Plutonium; Polysaccharides; Spleen | 1968 |
Effective dose of DTPA, spaced at 3-day intervals, in removal of skeletal plutonium. ANL-7535.
Topics: Animals; Bone and Bones; Female; Injections, Intraperitoneal; Liver; Mice; Pentetic Acid; Plutonium; Time Factors | 1968 |
Effect of DTPA and calcium on intraperitoneally injected 239PuO2 particles. BNWL-714.
Topics: Animals; Calcium; Female; Injections, Intraperitoneal; Ions; Pentetic Acid; Peritoneum; Phagocytosis; Plutonium; Rats; Time Factors | 1968 |
Plutonium-contaminated wound studies. BNWL-714.
Topics: Animals; Chelating Agents; Dimethyl Sulfoxide; Hydrogen-Ion Concentration; Pentetic Acid; Plutonium; Radiation Injuries, Experimental; Rats; Skin; Wounds and Injuries | 1968 |
Combined reticuloendothelial stimulation and long-term, intermittent DTPA therapy in poisoning by polymeric plutonium. ANL-7409.
Topics: Animals; Mice; Mononuclear Phagocyte System; Pentetic Acid; Plutonium; Poisoning; Polymers; Polysaccharides | 1967 |
Effect of DTPA on inhaled 239PuF4 in beagles. BNWL-1050.
Topics: Animals; Dogs; Pentetic Acid; Plutonium; Radiation Effects | 1970 |
[Effect of prophylactic inhalation of pentacine on remote results of Pu-239 inhalation].
Topics: Animals; Lung; Pentetic Acid; Plutonium; Radiation Effects; Radiation-Protective Agents; Rats | 1969 |
The effect of DTPA and calcium on the translocation of intraperitoneally administered 239Pu)O2 particles.
Topics: Animals; Calcium; Female; Injections, Intraperitoneal; Mesentery; Omentum; Oxides; Pentetic Acid; Plutonium; Rats | 1970 |
Kinetics of lymph node activity accummulation from subcutaneous PuO 2 implants.
Topics: Animals; Biological Transport; Body Burden; Dogs; Injections, Intradermal; Kinetics; Lymph Nodes; Oxides; Pentetic Acid; Plutonium; Radiation Monitoring; Radioactivity | 1970 |
Relative distribution of plutonium and americium following experimental PuO 2 implants.
Topics: Accidents, Occupational; Americium; Animals; Body Burden; Bone and Bones; Dogs; Eye; Feces; Injections, Subcutaneous; Kidney; Liver; Male; Methods; Nuclear Reactors; Oxides; Pentetic Acid; Plutonium; Radiation Injuries; Radiation Monitoring; Testis; Thyroid Gland; Wounds and Injuries | 1970 |
[Metabolic and therapeutic study of respiratory contamination by various actinic solutions].
Topics: Aerosols; Americium; Animals; Bone and Bones; Curium; Injections, Intramuscular; Lanthanum; Lung; Male; Muscles; Pentetic Acid; Plutonium; Pulmonary Alveoli; Radiation Injuries, Experimental; Radioisotopes; Rats; Respiratory System; Respiratory Tract Diseases; Salts; Solubility | 1971 |
[Prophylactic use of DTPA aerosols in chronic inhalations of Pu 239 in rats].
Topics: Aerosols; Animals; Environmental Exposure; Pentetic Acid; Plutonium; Pulmonary Fibrosis; Rats | 1968 |
Efficiency of low level DTPA therapy in removing plutonium from mice.
Topics: Animals; Injections, Intraperitoneal; Mice; Pentetic Acid; Plutonium; Radiation Injuries, Experimental; Radiation-Protective Agents; Time Factors; Vasopressins | 1969 |
Effective dose of DTPA, spaced at 3 day intervals, in removal of skeletal plutonium.
Topics: Animals; Bone and Bones; Femur; Injections, Intraperitoneal; Liver; Mice; Pentetic Acid; Plutonium; Spleen | 1969 |
Effectiveness of early DTPA treatments in two types of plutonium exposures in humans.
Topics: Blood; Feces; Humans; Male; Pentetic Acid; Plutonium; Radiation Injuries; Urine | 1965 |
Oral therapy for deposited plutonium.
Topics: Acetates; Animals; Bile; Chelating Agents; Drug Antagonism; Female; Ileum; Intestinal Absorption; Jejunum; Pentetic Acid; Plutonium; Rats | 1966 |
[On the comparative efficacy of desferrioxamine and DTPA as agents for the elimination of plutonium in poisoned rats].
Topics: Animals; Deferoxamine; Pentetic Acid; Plutonium; Rats | 1966 |
Influence of DTPA therapy on long-term effects of retained monomeric plutonium: comparison with polymeric plutonium.
Topics: Animals; Autoradiography; Bone and Bones; Bone Neoplasms; Female; Life Expectancy; Mice; Pentetic Acid; Plutonium; Radiation Injuries, Experimental | 1967 |
The effects of desferrioxamine on the retention of actinide elements in the rat.
Topics: Actinium; Americium; Animals; Curium; Deferoxamine; Femur; Kidney; Liver; Male; Pentetic Acid; Plutonium; Radiation Injuries, Experimental; Rats; Spleen; Thorium | 1967 |
Bio-assay and body counter results for the first 2 years following an acute plutonium exposure.
Topics: Hand; Hand Injuries; Humans; Male; Pentetic Acid; Plutonium; Radiation Effects; Radiation Injuries; Radiation Monitoring; Radiobiology | 1967 |
Investigations into techniques for removing intracellular plutonium--II. Complexing agents bound to macromolecules.
Topics: alpha-Fetoproteins; Animals; Asialoglycoproteins; Cellulose; Chelating Agents; Cricetinae; Cystine; Decontamination; Edetic Acid; Female; Liver; Mesocricetus; Pentetic Acid; Plutonium; Serum Albumin, Bovine | 1981 |
Computer simulation of metal ion equilibria in biofluids. IV. Plutonium speciation in human blood plasma and chelation therapy using polyaminopolycarboxylic acids.
Topics: Chelating Agents; Computers; Edetic Acid; Humans; Models, Biological; Pentetic Acid; Plutonium | 1984 |
DTPA is superior to its lipophilic derivative Puchel in removing 234Th, 238,239Pu and 241Am from Chinese hamsters and rats.
Topics: Americium; Animals; Bone and Bones; Cricetinae; Cricetulus; Decontamination; Female; Liver; Male; Pentetic Acid; Plutonium; Rats; Rats, Inbred Strains; Thorium | 1984 |
Decorporation of inhaled plutonium nitrate from hamsters using Zn-DTPA.
Topics: Aerosols; Animals; Cricetinae; Decontamination; Intubation, Intratracheal; Lung; Male; Mesocricetus; Nitrates; Pentetic Acid; Plutonium; Tissue Distribution | 1984 |
Effect of drinking Zn-DTPA on 238-Pu and 241-Am in rat bones.
Topics: Americium; Animals; Bone and Bones; Drug Combinations; Femur; Humerus; Male; Pentetic Acid; Plutonium; Rats; Rats, Inbred Strains; Water; Zinc | 1984 |
Liposomal encapsulated Zn-DTPA for removing intracellular 169Yb.
Topics: Animals; Body Fluids; Edetic Acid; Intracellular Fluid; Liposomes; Male; Pentetic Acid; Plutonium; Radioisotopes; Rats; Tissue Distribution; Ytterbium; Zinc | 1980 |
[Behavior and biological effect of 239Pu on entry into a skin abrasion].
Topics: Animals; Decontamination; Male; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Pentetic Acid; Plutonium; Rats; Rats, Inbred Strains; Tissue Distribution | 1983 |
Metabolism of plutonium introduced as Tri-N-Butylphosphate complex in the rat and removal attempts by DTPA.
Topics: Administration, Oral; Animals; Bone and Bones; Feces; Inhalation; Injections, Intramuscular; Liver; Lung; Male; Organometallic Compounds; Organophosphates; Organophosphorus Compounds; Pentetic Acid; Plutonium; Rats; Rats, Inbred Strains; Transferrin | 1983 |
The efficacy of Zn DTPA for the decorporation of 238Pu-TBP injected into the lungs of hamsters.
Topics: Animals; Colloids; Cricetinae; Feces; Lung; Male; Mesocricetus; Organometallic Compounds; Organophosphates; Organophosphorus Compounds; Pentetic Acid; Plutonium; Zinc | 1983 |
The effect of X rays, DTPA, and aspirin on the absorption of plutonium from the gastrointestinal tract of rats.
Topics: Animals; Aspirin; Biological Transport; Digestive System; Female; Intestinal Absorption; Pentetic Acid; Plutonium; Radiation, Ionizing; Rats; Rats, Inbred Strains; Therapeutic Irrigation; X-Rays | 1983 |
Decorporation of 238PuO2 from the hamster by inhalation of chelating agents.
Topics: Aerosols; Animals; Chelating Agents; Cricetinae; Decontamination; Lung; Male; Mesocricetus; Pentetic Acid; Plutonium; Respiration | 1982 |
Experimental study of respiratory contamination by a mixed oxide aerosol formed from the combustion of a plutonium magnesium alloy.
Topics: Aerosols; Alloys; Animals; Body Burden; Bone and Bones; Decontamination; Female; Liver; Lung; Magnesium; Male; Oxides; Pentetic Acid; Plutonium; Rats; Respiration | 1980 |
The use of Ca-DTPA as a treatment for plutonium inhaled in mixed oxide aerosols of plutonium and sodium.
Topics: Aerosols; Americium; Animals; Cricetinae; Inhalation; Injections, Intravenous; Lung; Male; Oxides; Pentetic Acid; Plutonium; Sodium; Tissue Distribution | 1980 |
The use of Puchel and DTPA for removing 238PuO2 from the lungs of hamsters.
Topics: Animals; Cricetinae; Decontamination; Lung; Male; Mesocricetus; Pentetic Acid; Plutonium | 1981 |
Investigations into techniques for removing intracellular plutonium-III.
Topics: Animals; Cricetinae; Kinetics; Pentetic Acid; Plutonium; Tissue Distribution | 1981 |
Oral chelation treatment of injected 241Am or 239Pu in rats.
Topics: Americium; Animals; Body Burden; Calcium; Chelating Agents; Drinking; Female; Injections, Intravenous; Intubation; Male; Pentetic Acid; Plutonium; Rats; Time Factors; Trientine; Zinc | 1980 |
Mixed ligand chelates and plutonium poisoning.
Topics: Animals; Drug Combinations; Female; Mice; Mice, Inbred CBA; Pentetic Acid; Plutonium; Sodium Salicylate | 1980 |
[Role of phagocytosis and the effect of different DTPA salts on the mechanism of lung self-purification of 239Pu].
Topics: Aerosols; Animals; Drug Evaluation, Preclinical; Humans; Lung; Pentetic Acid; Phagocytosis; Plutonium; Rats; Time Factors | 1980 |
Can mixed ligand therapy completely remove plutonium from the body?
Topics: Bone and Bones; Humans; Kidney; Ligands; Liver; Pentetic Acid; Plutonium | 1980 |
Salicylic acid failed to increase the efficacy of Ca-DTPA in the decorporation of plutonium and americium.
Topics: Americium; Animals; Calcium; Drug Synergism; Female; Male; Mice; Mice, Inbred C57BL; Pentetic Acid; Plutonium; Salicylates | 1980 |
Decorporation therapy for inhaled plutonium nitrate using repeatedly and continuously administered DTPA.
Topics: Administration, Inhalation; Animals; Decontamination; Dogs; Female; Injections, Intravenous; Male; Nitrates; Pentetic Acid; Plutonium; Time Factors | 1993 |
Early chelation therapy for injected Pu-238 and Am-241 in the rat: comparison of 3,4,3-LIHOPO, DFO-HOPO, DTPA-DX, DTPA and DFOA.
Topics: Administration, Oral; Americium; Animals; Chelating Agents; Deferoxamine; Female; Injections, Intravenous; Injections, Subcutaneous; Pentetic Acid; Plutonium; Rats; Rats, Sprague-Dawley | 1993 |
Removal of inhaled plutonium and americium from the rat by administration of ZnDTPA in drinking water.
Topics: Administration, Inhalation; Administration, Oral; Americium; Animals; Chelating Agents; Drinking; Female; Injections, Intraperitoneal; Lung; Metabolic Clearance Rate; Pentetic Acid; Plutonium; Rats; Rats, Inbred Strains | 1993 |
Comparative efficacies of 3,4,3-LIHOPO and DTPA for enhancing the excretion of plutonium and americium from the rat after simulated wound contamination as nitrates.
Topics: Americium; Animals; Aza Compounds; Decontamination; Female; Injections, Intramuscular; Injections, Subcutaneous; Pentetic Acid; Plutonium; Pyridones; Rats; Wounds and Injuries | 1993 |
Efficacy of 3,4,3-LIHOPO for enhancing the excretion of plutonium from rat after simulated wound contamination as a tributyl-n-phosphate complex.
Topics: Animals; Aza Compounds; Chelating Agents; Female; Organophosphates; Pentetic Acid; Plutonium; Pyridones; Rats; Rats, Sprague-Dawley; Wounds and Injuries | 1995 |
Optimising the removal of inhaled plutonium and americium from the rat by administration of ZnDTPA in drinking water.
Topics: Administration, Inhalation; Administration, Oral; Americium; Animals; Chelating Agents; Colon; Drinking; Duodenum; Female; Ileum; Injections, Intraperitoneal; Kidney; Liver; Lung; Pentetic Acid; Plutonium; Rats; Zinc | 1995 |
Circulatory kinetics of intravenously injected 238Pu(IV) citrate and 14C-CaNa3-DTPA in mice: comparison with rat, dog, and reference man.
Topics: Animals; Carbon Radioisotopes; Citric Acid; Dogs; Female; Humans; Injections, Intravenous; Kidney; Kinetics; Liver; Metabolic Clearance Rate; Mice; Models, Biological; Pentetic Acid; Plutonium; Rats; Species Specificity; Tissue Distribution | 1997 |
[Modeling of cutaneous radio-contamination: effects of washings by soap and by solutions of DTPA].
Topics: Burns, Chemical; Cesium Radioisotopes; Models, Biological; Pentetic Acid; Plutonium; Skin; Soaps; Therapeutic Irrigation | 1997 |
Topological structure activity analysis of diphosphonates in the elimination of radionuclides from body.
Topics: Animals; Chelating Agents; Cobalt Radioisotopes; Diphosphonates; Male; Pentetic Acid; Plutonium; Rats; Rats, Wistar; Spermidine; Structure-Activity Relationship | 1997 |
Effect of oral ZnDTPA on late effects of injected plutonium in rat.
Topics: Administration, Oral; Animals; Bone and Bones; Bone Neoplasms; Glomerulosclerosis, Focal Segmental; Male; Mammary Neoplasms, Experimental; Osteosarcoma; Pentetic Acid; Plutonium; Radiometry; Rats; Rats, Sprague-Dawley; Survival Rate; Time Factors; Tissue Distribution | 1999 |
[Efficiency of etidronic acid in the case of cutaneous radiocontamination by actinid elements: in vitro evaluation].
Topics: Chelating Agents; Decontamination; Etidronic Acid; Humans; Organ Culture Techniques; Pentetic Acid; Plutonium; Skin; Uranium | 2000 |
Synthesis and initial evaluation for in vivo chelation of Pu(IV) of a mixed octadentate spermine-based ligand containing 4-carbamoyl-3-hydroxy-1-methyl-2(1H)-pyridinone and 6-carbamoyl-1-hydroxy-2(1H)-pyridinone.
Topics: Administration, Oral; Animals; Chelating Agents; Dose-Response Relationship, Drug; Female; Injections, Intravenous; Ligands; Mice; Pentetic Acid; Plutonium; Pyridones; Spermine; Structure-Activity Relationship; Toxicity Tests, Acute | 2002 |
Comparative uptake of plutonium from soils by Brassica juncea and Helianthus annuus.
Topics: Biodegradation, Environmental; Brassica; Chelating Agents; Citrates; Geologic Sediments; Helianthus; Nitrates; Pentetic Acid; Plutonium; Soil Pollutants, Radioactive | 2002 |
THE METABOLISM OF BIOLOGICALLY IMPORTANT RADIONUCLIDES. VIII. SOME ASPECTS OF THE PREVENTION AND TREATMENT OF EXCESSIVE INTERNAL RADIOACTIVE CONTAMINATION.
Topics: Chelating Agents; Humans; Metabolism; Pentetic Acid; Plutonium; Radiation Protection; Radioactivity; Radioisotopes | 1964 |
PROGRESS REPORT: PLUTONIUM REMOVAL, TUMOR INCIDENCE STUDIES. III. ANL-6723.
Topics: Bone and Bones; Chelating Agents; Cohort Studies; Metabolism; Mice; Neoplasms; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Pentetic Acid; Pharmacology; Plutonium; Research; Research Report; Toxicology | 1963 |
PROGRESS REPORT: PLUTONIUM REMOVAL. TUMOR INCIDENCE STUDIES. V. ANL-6823.
Topics: Animals; Bone Neoplasms; Chelating Agents; Cohort Studies; Injections, Intravenous; Mice; Neoplasms; Neoplasms, Radiation-Induced; Pentetic Acid; Plutonium; Research; Research Report | 1964 |
[EFFECT OF NA3CA-DTPA (PENTACINE) ON EXCRETION OF PU239 FROM THE HUMAN BODY].
Topics: Biological Transport; Body Fluids; Chelating Agents; Feces; Human Body; Humans; Pentetic Acid; Plutonium; Radioisotopes; Radionuclide Imaging; Urine | 1964 |
THE EFFECT OF DTPA TREATMENT AFTER ADMINISTRATION TO RATS OF 239PU(VI) IN NITRIC ACID.
Topics: Body Fluids; Chelating Agents; Feces; Fluids and Secretions; Injections, Intraperitoneal; Nitrates; Nitric Acid; Pentetic Acid; Plutonium; Radiation Effects; Radiation-Protective Agents; Rats; Research; Toxicology; Urine | 1964 |
DISTRIBUTION AND REMOVAL OF MONOMERIC AND POLYMERIC PLUTONIUM IN RATS AND MICE.
Topics: Animals; Bone and Bones; Chelating Agents; Feces; Fluids and Secretions; Liver; Metabolism; Mice; Pentetic Acid; Plutonium; Radiation Effects; Rats; Research; Urine | 1964 |
REVIEW OF THERAPEUTIC PROCEDURES FOR REMOVAL OF INHALED RADIOACTIVE MATERIALS.
Topics: Air Pollution; Air Pollution, Radioactive; Cerium Isotopes; Chelating Agents; Metabolism; Pentetic Acid; Pharmacology; Plutonium; Radiation-Protective Agents; Radioactivity; Radioisotopes; Ruthenium; Strontium Isotopes | 1964 |
Successful DTPA therapy in the case of 239Pu penetration via injured skin exposed to nitric acid.
Topics: Administration, Topical; Burns, Chemical; Chelating Agents; Chelation Therapy; Decontamination; Humans; Injections, Intravenous; Male; Nitrates; Occupational Exposure; Pentetic Acid; Plutonium; Radiation Injuries; Radiation Protection; Radioactive Hazard Release; Skin; Treatment Outcome; Whole-Body Counting | 2003 |
An analysis of a puncture wound case with medical intervention.
Topics: Administration, Inhalation; Administration, Topical; Americium; Chelating Agents; Chelation Therapy; Humans; Male; Middle Aged; Pentetic Acid; Plutonium; Radiation Injuries; Thumb; Whole-Body Counting; Wounds, Penetrating | 2003 |
Competitive binding of Pu and Am with bone mineral and novel chelating agents.
Topics: Americium; Binding Sites; Bone and Bones; Bone Density; Chelating Agents; Chelation Therapy; Crystallization; Durapatite; Ligands; Macromolecular Substances; Pentetic Acid; Plutonium | 2003 |
Comparative decorporation efficacy of 3,4,3-LIHOPO, 4,4,4-LIHOPO and DTPA after contamination of rats with soluble forms of 238Pu and 233U.
Topics: Animals; Aza Compounds; Body Burden; Chelating Agents; Chelation Therapy; Decontamination; Dose-Response Relationship, Drug; Femur; Injections, Intravenous; Liver; Male; Pentetic Acid; Plutonium; Pyridones; Radiation Injuries; Rats; Rats, Sprague-Dawley; Treatment Outcome; Uranium; Whole-Body Counting | 2003 |
Targeting of diethylene triamine pentaacetic acid encapsulated in liposomes to rat liver: an effective strategy to prevent bone deposition and increase urine elimination of plutonium in rats.
Topics: Animals; Bone and Bones; Chelating Agents; Liposomes; Liver; Male; Pentetic Acid; Plutonium; Rats; Rats, Sprague-Dawley; Spleen; Tissue Distribution | 2004 |
Treatment of accidental intakes of plutonium and americium: guidance notes.
Topics: Americium; Humans; Pentetic Acid; Plutonium; Poisoning; Practice Guidelines as Topic | 2005 |
[Emergency care for acute wound entering of plutonium and americium into the body (real case)].
Topics: Adult; Americium; Antidotes; Critical Care; Dermatologic Surgical Procedures; Humans; Injections, Intravenous; Male; Occupational Exposure; Pentetic Acid; Plutonium; Potassium Permanganate; Radiation Injuries; Radiometry; Skin; Therapeutic Irrigation; Wound Healing; Wounds, Penetrating | 2005 |
Pharmacokinetics of DTPA entrapped in conventional and long-circulating liposomes of different size for plutonium decorporation.
Topics: Animals; Carbon Radioisotopes; Chelating Agents; Chemistry, Pharmaceutical; Injections, Intravenous; Liposomes; Male; Particle Size; Pentetic Acid; Plutonium; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Tissue Distribution | 2005 |
Efficacy of orally administered amphipathic polyaminocarboxylic acid chelators for the removal of plutonium and americium: comparison with injected Zn-DTPA in the rat.
Topics: Acetates; Administration, Oral; Americium; Animals; Bone Marrow; Carboxylic Acids; Chelating Agents; Dose-Response Relationship, Drug; Liver; Male; Pentetic Acid; Plutonium; Rats; Rats, Sprague-Dawley; Time Factors; Tissue Distribution; Trientine | 2006 |
Enhanced decorporation of plutonium by DTPA encapsulated in small PEG-coated liposomes.
Topics: Animals; Feces; Hepatocytes; Kinetics; Kupffer Cells; Liposomes; Pentetic Acid; Phytic Acid; Plutonium; Rats; Tissue Distribution | 2006 |
Predicting plutonium decorporation efficacy after intravenous administration of DTPA formulations: Study of pharmacokinetic-pharmacodynamic relationships in rats.
Topics: Animals; Area Under Curve; Chelating Agents; Chemistry, Pharmaceutical; Drug Carriers; Half-Life; Injections, Intravenous; Liposomes; Male; Pentetic Acid; Plutonium; Predictive Value of Tests; Rats; Rats, Sprague-Dawley | 2006 |
Direct lung delivery of a dry powder formulation of DTPA with improved aerosolization properties: effect on lung and systemic decorporation of plutonium.
Topics: Administration, Inhalation; Aerosols; Animals; Chelating Agents; Chemistry, Pharmaceutical; Drug Stability; Lung; Male; Microscopy, Electron, Scanning; Particle Size; Pentetic Acid; Plutonium; Porosity; Powders; Rats; Rats, Sprague-Dawley; X-Ray Diffraction | 2007 |
Treatment of human contamination with plutonium and americium: would orally administered Ca- or Zn-DTPA be effective?
Topics: Administration, Oral; Americium; Biological Assay; Body Burden; Chelating Agents; Computer Simulation; Humans; Models, Biological; Pentetic Acid; Plutonium; Radiation Dosage; Radiation Injuries; Radiation-Protective Agents; Radiometry; Relative Biological Effectiveness; Reproducibility of Results; Sensitivity and Specificity | 2007 |
Modelling of bioassay data from a Pu wound treated by repeated DTPA perfusions: biokinetics and dosimetric approaches.
Topics: Adult; Biological Assay; Body Burden; Chelating Agents; Computer Simulation; Foreign Bodies; Humans; Kinetics; Male; Metabolic Clearance Rate; Models, Biological; Pentetic Acid; Plutonium; Radiation Injuries; Radiation-Protective Agents; Radiometry; Relative Biological Effectiveness; Treatment Outcome; Wounds, Penetrating | 2007 |
Decorporation of plutonium by pulmonary administration of Ca-DTPA dry powder: a study in rat after lung contamination with different plutonium forms.
Topics: Administration, Inhalation; Air Pollutants, Radioactive; Animals; Chelating Agents; Dose-Response Relationship, Drug; Inhalation Exposure; Male; Metabolic Clearance Rate; Pentetic Acid; Plutonium; Powders; Radiation Injuries; Radiation-Protective Agents; Rats; Rats, Sprague-Dawley; Treatment Outcome | 2007 |
Derivation and validation of a urinary excretion function for plutonium based on occupational exposure.
Topics: Air Pollution, Radioactive; Chelating Agents; Computer Simulation; Humans; Inhalation Exposure; Occupational Exposure; Pentetic Acid; Plutonium; Power Plants; Radiation Injuries; Radiation Monitoring | 2008 |
Ustur whole body case 0269: demonstrating effectiveness of i.v. CA-DTPA for Pu.
Topics: Biological Assay; Body Burden; Chelating Agents; Computer Simulation; Drug Administration Schedule; Humans; Male; Models, Biological; Pentetic Acid; Plutonium; Radiation Dosage; Radiation Injuries; Radiation-Protective Agents; Radiometry; Relative Biological Effectiveness; Reproducibility of Results; Sensitivity and Specificity; Treatment Outcome; Whole-Body Counting | 2007 |
Diethylene-triamine-penta-acetate administration protocol for radiological emergency medicine in nuclear fuel reprocessing plants.
Topics: Administration, Inhalation; Americium; Chelating Agents; Clinical Protocols; Curium; Humans; Nebulizers and Vaporizers; Pentetic Acid; Plutonium; Power Plants; Radiation Injuries; Radioactive Hazard Release; Radioactive Pollutants | 2008 |
In vitro and in vivo assessment of plutonium speciation and decorporation in blood and target retention tissues after a systemic contamination followed by an early treatment with DTPA.
Topics: Animals; Chelating Agents; Decontamination; Male; Organ Specificity; Pentetic Acid; Plutonium; Rats; Rats, Sprague-Dawley; Tissue Distribution; Viscera | 2008 |
Lauriston S. Taylor Lecture: the quest for therapeutic actinide chelators.
Topics: Actinoid Series Elements; Americium; Animals; Chelating Agents; Deferoxamine; Edetic Acid; Humans; Mice; Pentetic Acid; Phenols; Plutonium; Uranium | 2008 |
Simplified structure of a new model to describe urinary excretion of plutonium after systemic, liver or pulmonary contamination of rats associated with Ca-DTPA treatments.
Topics: Analysis of Variance; Animals; Autoradiography; Bone and Bones; Citric Acid; Feces; Half-Life; Kinetics; Liver; Lung; Male; Models, Biological; Pentetic Acid; Plutonium; Radiation Injuries, Experimental; Radiation-Protective Agents; Rats; Rats, Sprague-Dawley; Time Factors | 2009 |
Pharmacological properties of orally available, amphipathic polyaminocarboxylic acid chelators for actinide decorporation.
Topics: Acetates; Administration, Oral; Americium; Autoradiography; Biological Availability; Carbon Radioisotopes; Chelating Agents; Decontamination; Intestinal Absorption; Pentetic Acid; Plutonium; Trientine | 2010 |
Functional sorbents for selective capture of plutonium, americium, uranium, and thorium in blood.
Topics: Actinoid Series Elements; Adsorption; Americium; Chelating Agents; Decontamination; Humans; Isomerism; Pentetic Acid; Plutonium; Porosity; Pyridones; Radiation Injuries; Radioactive Hazard Release; Terrorism; Thorium; Time Factors; Uranium | 2010 |
Preferential decorporation of americium by pulmonary administration of DTPA dry powder after inhalation of aged PuO(2) containing americium in rats.
Topics: Americium; Animals; Chelating Agents; Inhalation; Lung; Male; Pentetic Acid; Plutonium; Powders; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Time Factors | 2010 |
Twenty-four years of follow-up for a Hanford plutonium wound case.
Topics: Accidents, Occupational; Adult; Americium; Biological Assay; Body Burden; Chelation Therapy; Fingers; Follow-Up Studies; Humans; Lymph Nodes; Male; Models, Biological; Nuclear Reactors; Occupational Exposure; Pentetic Acid; Plutonium; Radiation Injuries; Time Factors; Tissue Distribution; Washington; Wounds, Penetrating | 2010 |
Three plutonium chelation cases at Los Alamos National Laboratory.
Topics: Body Burden; Calibration; Chelating Agents; Computer Simulation; Decontamination; Humans; Laboratories; New Mexico; Nuclear Physics; Occupational Exposure; Pentetic Acid; Plutonium; Radiation Injuries; Radiation-Protective Agents; Relative Biological Effectiveness; Time Factors | 2010 |
The CONRAD approach to biokinetic modeling of DTPA decorporation therapy.
Topics: Body Burden; Carbon Radioisotopes; Chelating Agents; Decontamination; Humans; Lymph; Models, Biological; Pentetic Acid; Plutonium; Radiation Injuries; Radiometry; Relative Biological Effectiveness; Staining and Labeling | 2010 |
Structure of a single model to describe plutonium and americium decorporation by DTPA treatments.
Topics: Americium; Animals; Autoradiography; Decontamination; Feces; Inhalation Exposure; Injections, Intravenous; Male; Models, Biological; Pentetic Acid; Plutonium; Radiation-Protective Agents; Rats; Rats, Sprague-Dawley; Time Factors; Tissue Distribution | 2010 |
A case of wound intake of plutonium isotopes and 241Am in a human: application and improvement of the NCRP wound model.
Topics: Americium; Decontamination; Fingers; Humans; Injections, Intravenous; Lymph Nodes; Male; Middle Aged; Models, Biological; Nuclear Power Plants; Occupational Exposure; Pentetic Acid; Plutonium; Radiation Injuries; Radiation-Protective Agents; Russia; Time Factors; Treatment Outcome; Wounds, Penetrating | 2010 |
EURADOS coordinated action on research, quality assurance and training of internal dose assessments.
Topics: Americium; Europe; Humans; Kinetics; Monte Carlo Method; Pentetic Acid; Plutonium; Quality Control; Radiation Monitoring; Radioisotopes; Radiometry; Reference Values; Registries; Reproducibility of Results; Uranium | 2011 |
[Pharmacological properties and clinical efficacy of pentetate calcium trisodium and pentetate zinc trisodium, antidotes for transuranium elements].
Topics: Americium; Animals; Antidotes; Calcium; Chelating Agents; Curium; Humans; Pentetic Acid; Plutonium; Zinc | 2012 |
Uptake, distribution, and velocity of organically complexed plutonium in corn (Zea mays).
Topics: Chelating Agents; Deferoxamine; Hydroponics; Pentetic Acid; Plutonium; Radiation Monitoring; Scintillation Counting; Siderophores; Soil Pollutants, Radioactive; Spectrometry, Gamma; Time Factors; Zea mays | 2012 |
Aqueous complexation of thorium(IV), uranium(IV), neptunium(IV), plutonium(III/IV), and cerium(III/IV) with DTPA.
Topics: Cerium; Electrochemical Techniques; Neptunium; Organometallic Compounds; Pentetic Acid; Plutonium; Thermodynamics; Thorium; Uranium; Water | 2012 |
Decorporation approach following rat lung contamination with a moderately soluble compound of plutonium using local and systemic Ca-DTPA combined chelation.
Topics: Animals; Chelating Agents; Lung; Male; Nitrates; Pentetic Acid; Plutonium; Powders; Rats; Rats, Sprague-Dawley; Solubility; Solutions; Time Factors | 2012 |
Actinide handling after wound entry with local or systemic decorporation therapy in the rat.
Topics: Actinoid Series Elements; Americium; Animals; Chelating Agents; Male; Muscle, Skeletal; Nitrates; Oxides; Pentetic Acid; Plutonium; Radiation Injuries; Rats; Rats, Sprague-Dawley; Uranium Compounds; Wound Healing | 2014 |
REMOVAL OF INHALED RADIOACTIVE PARTICLES. HW-76000.
Topics: Aerosols; Cerium; Chelating Agents; Dogs; Feces; Metabolism; Pentetic Acid; Pharmacology; Phenylephrine; Plutonium; Radioactivity; Rats; Research; Urine | 1963 |
PREVENTION OF PLUTONIUM AND NEPTUNIUM DEPOSITION. HW-76000.
Topics: Chelating Agents; Liver; Metabolism; Neptunium; Pentetic Acid; Pharmacology; Plutonium; Radiation Injuries; Radiation Injuries, Experimental; Rats; Research; Toxicology; Ultrasonic Therapy | 1963 |
EFFECTS OF PLUTONIUM IN SKIN AND IN REMOVAL. HW-76000.
Topics: Animals; Bone and Bones; Chelating Agents; Liver; Lymph Nodes; Metabolism; Pentetic Acid; Pharmacology; Plutonium; Radiation Injuries; Radiation Injuries, Experimental; Research; Skin; Swine | 1963 |
EXCRETION OF PLUTONIUM INTO THE PERFUSED RAT INTESTINE. HW-76000.
Topics: Bile; Chelating Agents; Duodenum; Intestine, Small; Intestines; Pentetic Acid; Perfusion; Pharmacology; Physiology; Plutonium; Rats; Research | 1963 |
ATTEMPTS TO REMOVE INHALED PLUTONIUM. HW-80500.
Topics: Chelating Agents; Lung; Pathology; Pentetic Acid; Pharmacology; Plutonium; Radiation Effects; Rats; Research; Toxicology | 1964 |
Combined drug and surgery treatment of plutonium-contaminated wounds: indications obtained using a rodent model.
Topics: Animals; Disease Models, Animal; Histones; Male; Pentetic Acid; Phosphoproteins; Plutonium; Radioactive Hazard Release; Rats; Rats, Sprague-Dawley; Wounds and Injuries | 2014 |
Developing a physiologically based approach for modeling plutonium decorporation therapy with DTPA.
Topics: Algorithms; Animals; Bone and Bones; Chelating Agents; Chelation Therapy; Humans; Kidney; Liver; Pentetic Acid; Plutonium; Rats; Software; Transferrin | 2014 |
Development of the Plutonium-DTPA Biokinetic Model.
Topics: Humans; Models, Biological; Pentetic Acid; Plutonium; Receptors, Transferrin; Transferrin; Wounds and Injuries | 2015 |
Design and functionalities of the MADOR® software suite for dose-reduction management after DTPA therapy.
Topics: Americium; Body Burden; Chelating Agents; Humans; Kinetics; Models, Biological; Occupational Exposure; Pentetic Acid; Plutonium; Radiation Dosage; Radiation Injuries; Radiometry; Software | 2016 |
Plutonium-DTPA Model Application with USTUR Case 0269.
Topics: Aerosols; Autopsy; Biological Assay; Bone and Bones; Chelating Agents; Feces; Follow-Up Studies; Humans; Lung; Male; Models, Biological; Nitrates; Pentetic Acid; Plutonium; Radiation Injuries; Radiation-Protective Agents; Radiometry; Relative Biological Effectiveness; Tissue Distribution; United States | 2016 |
Influence of DTPA Treatment on Internal Dose Estimates.
Topics: Americium; Body Burden; Chelating Agents; Decontamination; Dose-Response Relationship, Drug; Feces; Humans; Pentetic Acid; Plutonium; Radiation Dosage; Radiation Exposure; Radiation-Protective Agents; Reproducibility of Results; Sensitivity and Specificity | 2016 |
Decorporation of Pu/Am Actinides by Chelation Therapy: New Arguments in Favor of an Intracellular Component of DTPA Action.
Topics: Americium; Animals; Bone and Bones; Chelating Agents; Dose-Response Relationship, Drug; Intracellular Space; Kinetics; Liver; Male; Pentetic Acid; Plutonium; Rats; Rats, Sprague-Dawley | 2016 |
Potential of Vetiveria zizanoides L. Nash for phytoremediation of plutonium ((239)Pu): Chelate assisted uptake and translocation.
Topics: Biodegradation, Environmental; Chelating Agents; Chrysopogon; Citric Acid; Hydroponics; Pentetic Acid; Plant Roots; Plant Shoots; Plutonium; Soil Pollutants | 2016 |
In vitro assessment of plutonium uptake and release using the human macrophage-like THP-1 cells.
Topics: Animals; Cell Line, Tumor; Cells, Cultured; Chelating Agents; Humans; Macrophages; Male; Pentetic Acid; Phagocytosis; Plutonium; Rats, Sprague-Dawley; Solubility | 2016 |
The Impact of Time on Decorporation Efficacy After a "Dirty Bomb" Attack Studied by Simulation.
Topics: Americium; Cesium; Computer Simulation; Decontamination; Ferrocyanides; Inhalation Exposure; Models, Biological; Nuclear Weapons; Pentetic Acid; Plutonium; Radioisotopes; Radiometry; Time Factors | 2016 |
Interpretation of Urinary Excretion Data From Plutonium Wound Cases Treated With DTPA: Application of Different Models and Approaches.
Topics: Chelation Therapy; Computer Simulation; Humans; Male; Metabolic Clearance Rate; Models, Biological; Pentetic Acid; Plutonium; Radiation Dosage; Radiation Injuries; Radiation Monitoring; Treatment Outcome; Urination; Wounds, Penetrating | 2017 |
Decorporation Approach after Rat Lung Contamination with Plutonium: Evaluation of the Key Parameters Influencing the Efficacy of a Protracted Chelation Treatment.
Topics: Animals; Calcium; Chelating Agents; Lung; Male; Pentetic Acid; Plutonium; Rats; Rats, Sprague-Dawley; Zinc | 2017 |
USTUR WHOLE-BODY CASE 0212: 17-YEAR FOLLOW-UP OF PLUTONIUM CONTAMINATED WOUND.
Topics: Chelating Agents; Combined Modality Therapy; Fatal Outcome; Finger Injuries; Humans; Male; Middle Aged; Nitrates; Occupational Exposure; Pentetic Acid; Plutonium; Radiation Injuries; Whole-Body Counting | 2018 |
Second-order Kinetics of DTPA and Plutonium in Rat Plasma.
Topics: Animals; Chelating Agents; Kinetics; Molecular Weight; Pentetic Acid; Plutonium; Rats | 2018 |
Delivery of DTPA through Liposomes as a Good Strategy for Enhancing Plutonium Decorporation Regardless of Treatment Regimen.
Topics: Animals; Liposomes; Male; Pentetic Acid; Plutonium; Rats; Rats, Sprague-Dawley; Tissue Distribution | 2018 |
Rapid Response, Dose Assessment, and Clinical Management of a Plutonium-contaminated Puncture Wound.
Topics: Chelating Agents; Chelation Therapy; Decontamination; Disease Management; Dose-Response Relationship, Radiation; Humans; Pentetic Acid; Plutonium; Radiation Exposure; Radiation Injuries; Radiation Monitoring; Wounds, Penetrating | 2018 |
ENCAPSULATED 3,4,3-LI(1,2-HOPO) IN CHITOSAN NANOPARTICLES FOR DECORPORATION VIA INHALATION.
Topics: Actinoid Series Elements; Administration, Inhalation; Americium; Body Fluids; Chelating Agents; Chitosan; Decontamination; Heterocyclic Compounds, 1-Ring; Humans; Lung; Nanoparticles; Pentetic Acid; Plutonium; Pyridones; Radiation Dosage | 2018 |
AN ACCIDENT OF INTERNAL CONTAMINATION WITH PLUTONIUM AND AMERICIUM AT A NUCLEAR FACILITY IN JAPAN: A PRELIMINARY REPORT AND THE POSSIBILITY OF DTPA ADMINISTRATION ADDING TO THE DIAGNOSIS.
Topics: Americium; Chelating Agents; Humans; Japan; Neoplasms, Radiation-Induced; Occupational Exposure; Pentetic Acid; Plutonium; Radiation Dosage; Radiation Injuries; Radioactive Hazard Release; Risk Factors | 2018 |
Improved Modeling of Plutonium-DTPA Decorporation.
Topics: Biological Assay; Chelating Agents; Humans; Models, Biological; Models, Chemical; Occupational Exposure; Pentetic Acid; Plutonium; Postmortem Changes; Radiation Dosage; Tissue Distribution | 2019 |
Validation of a system of models for plutonium decorporation therapy.
Topics: Air Pollutants, Radioactive; Bone and Bones; Chelating Agents; Edetic Acid; Gastrointestinal Tract; Humans; Inhalation Exposure; Liver; Models, Biological; Occupational Exposure; Pentetic Acid; Plutonium; Radiation Injuries; Respiratory System | 2019 |
A quick and simple in vitro assay to predict bioavailability of actinides following accidental exposure.
Topics: Americium; Biological Assay; Biological Availability; Body Fluids; Bone and Bones; Chelating Agents; Citrates; Colloids; Lung; Nitrates; Pentetic Acid; Plutonium; Pyridones; Radiation Exposure; Radioactive Hazard Release; Transferrin; Uranium | 2019 |
Chelation Treatment by Early Inhalation of Liquid Aerosol DTPA for Removing Plutonium after Rat Lung Contamination.
Topics: Administration, Inhalation; Aerosols; Animals; Chelating Agents; Lung; Male; Pentetic Acid; Plutonium; Radiation Injuries; Rats; Rats, Sprague-Dawley | 2019 |
Comments on "Improved Modeling of Plutonium-DTPA Decorporation" (Radiat Res 2019; 191:201-10).
Topics: Chelating Agents; Pentetic Acid; Plutonium | 2019 |
Response to the Letter to the Editor, 'Comments on "Improved Modeling of Plutonium-DTPA Decorporation," (Radiat Res 2019; 191:201-10) by Gremy and Miccoli'.
Topics: Chelating Agents; Pentetic Acid; Plutonium | 2019 |
Power Function Retention of Radionuclides in a Wound.
Topics: Aged; Americium; Chelating Agents; Computer Simulation; Humans; Male; Models, Biological; Pentetic Acid; Plutonium; Radiation Injuries; Radioactive Hazard Release; Radioisotopes; Solubility; Thumb; Wounds, Penetrating | 2021 |
DTPA-Coated Liposomes as a New Delivery Vehicle for Plutonium Decorporation.
Topics: Animals; Bone and Bones; Chelating Agents; Humans; Liposomes; Liver; Male; Pentetic Acid; Plutonium; Rats; Rats, Sprague-Dawley; Spleen | 2021 |
Development of a New Chelation Model: Bioassay Data Interpretation and Dose Assessment after Plutonium Intake via Wound and Treatment with DTPA.
Topics: Biological Assay; Bone and Bones; Chelating Agents; Chelation Therapy; Data Interpretation, Statistical; Feces; Humans; Liver; Male; Models, Biological; Occupational Exposure; Pentetic Acid; Plutonium; Radiation Dosage; Radiation Injuries; Urinalysis; Wounds, Penetrating | 2020 |
DTPA Treatment of Wound Contamination in Rats with Americium: Evaluation of Urinary Profiles Using STATBIODIS Shows Importance of Prompt Administration.
Topics: Americium; Animals; Chelating Agents; Liver; Pentetic Acid; Plutonium; Radiation Exposure; Rats | 2021 |
Four-decade follow-up of a plutonium-contaminated puncture wound treated with Ca-DTPA.
Topics: Follow-Up Studies; Humans; Models, Biological; Pentetic Acid; Plutonium; Punctures; Radiation Injuries | 2021 |
Interpretation of Enhanced Fecal and Urinary Plutonium Excretion Data under a 2-y Regular DTPA Treatment Started Months after Intake.
Topics: Chelating Agents; Feces; Humans; Kinetics; Pentetic Acid; Plutonium | 2021 |
URINARY EXCRETION OF PLUTONIUM IN MAYAK WORKERS DURING AND AFTER CA-DTPA ADMINISTRATION.
Topics: Biological Assay; Chelating Agents; Female; Humans; Male; Occupational Exposure; Pentetic Acid; Plutonium | 2021 |
Excretion of Pu-238 during Long-term Chelation Therapy by Repeated DTPA Inhalation.
Topics: Aerosols; Chelating Agents; Chelation Therapy; Humans; Pentetic Acid; Plutonium | 2022 |
In Vitro and In Vivo Evaluation of DTPA-HPMA Copolymers as Potential Decorporating Agents for Prophylactic Therapy of Actinide Contamination.
Topics: Actinoid Series Elements; Animals; Chelating Agents; Decontamination; Endothelial Cells; Humans; Methacrylates; Mice; Pentetic Acid; Plutonium; Polyamines; Polymers | 2022 |
Use of an Acellular Assay to Study Interactions between Actinides and Biological or Synthetic Ligands.
Topics: Actinoid Series Elements; Americium; Ligands; Pentetic Acid; Plutonium | 2022 |
Chelation Model Validation: Modeling of a Plutonium-238 Inhalation Incident Treated with DTPA at Los Alamos National Laboratory.
Topics: Chelating Agents; Humans; Pentetic Acid; Plutonium; Radiation Injuries | 2023 |
Chelation therapy with 3,4,3-Li(1,2-HOPO) after pulmonary exposure to plutonium in rats.
Topics: Animals; Chelating Agents; Chelation Therapy; Lithium; Lung; Pentetic Acid; Plutonium; Rats | 2023 |
Biokinetic model analysis with DTPA administration for a case of accidental inhalation of actinides in Japan.
Topics: Accidents; Administration, Inhalation; Americium; Chelating Agents; Humans; Japan; Pentetic Acid; Plutonium; Radiation Injuries | 2023 |
Modelling DTPA therapy following Am contamination in rats.
Topics: Americium; Animals; Chelating Agents; Humans; Models, Biological; Pentetic Acid; Plutonium; Rats | 2023 |