plerixafor has been researched along with amd 070 in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Becker, S; Calandra, GB; Cao, YJ; Conley, J; Dunaway, SB; Flexner, C; Hendrix, CW; Kallungal, B; Klingman, KL; Lalama, C; MacFarland, RT; Park, JG; Snyder, S; Stone, ND; Tierney, C; Wiggins, IP | 1 |
| Hamatake, M; Huang, W; Komano, J; Kumakura, S; Murakami, T; Okuma, K; Tanaka, R; Tanaka, Y; Toma, J; Yamamoto, N; Yamazaki, T; Yanaka, M | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Bodart, V; Bridger, G; Fricker, SP; Labrecque, J; Metz, M; Wong, RS | 1 |
| Neves, MA; Sá e Melo, ML; Simões, S | 1 |
| Hosoya, N; Iwamoto, A; Kawana-Tachikawa, A | 1 |
| Groffen, J; Heisterkamp, N; Lim, M; Parameswaran, R; Yu, M | 1 |
| Benned-Jensen, T; Berg, C; Daugvilaite, V; De Filippo, K; Hjortø, G; Juzenaite, G; Jørgensen, AS; Mavri, M; Rankin, S; Rosenkilde, MM; Våbenø, J | 1 |
1 review(s) available for plerixafor and amd 070
| Article | Year |
|---|---|
HIV-1 tropism.
Topics: Aminoquinolines; Anti-HIV Agents; Benzimidazoles; Benzylamines; Butylamines; CCR5 Receptor Antagonists; CD4 Antigens; Cyclams; Cyclohexanes; Heterocyclic Compounds; Heterocyclic Compounds, 1-Ring; HIV-1; Humans; Maraviroc; Piperazines; Pyrimidines; Receptors, CCR5; Receptors, CXCR4; T-Lymphocytes; Triazoles; Viral Tropism | 2010 |
1 trial(s) available for plerixafor and amd 070
| Article | Year |
|---|---|
Multiple-dose escalation study of the safety, pharmacokinetics, and biologic activity of oral AMD070, a selective CXCR4 receptor inhibitor, in human subjects.
Topics: Administration, Oral; Adolescent; Adult; Aminoquinolines; Area Under Curve; Benzimidazoles; Butylamines; Cohort Studies; Dose-Response Relationship, Drug; Fasting; Half-Life; Headache; Heterocyclic Compounds, 1-Ring; Humans; Leukocytes; Male; Middle Aged; Receptors, CXCR4; Time Factors | 2007 |
6 other study(ies) available for plerixafor and amd 070
| Article | Year |
|---|---|
The novel CXCR4 antagonist KRH-3955 is an orally bioavailable and extremely potent inhibitor of human immunodeficiency virus type 1 infection: comparative studies with AMD3100.
Topics: Animals; Anti-HIV Agents; Calcium Signaling; Cell Line; Cells, Cultured; Chemokine CXCL12; CHO Cells; Cricetinae; Cricetulus; Fluorescent Antibody Technique; HIV Infections; HIV-1; Humans; Mice; Mice, SCID; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, CXCR4 | 2009 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Comparison of the potential multiple binding modes of bicyclam, monocylam, and noncyclam small-molecule CXC chemokine receptor 4 inhibitors.
Topics: Aminoquinolines; Animals; Anti-HIV Agents; Benzimidazoles; Benzylamines; Binding Sites; Binding, Competitive; Butylamines; Cell Fusion; Cell Line; Cricetinae; Cricetulus; Cyclams; Heterocyclic Compounds; Heterocyclic Compounds, 1-Ring; Humans; Ligands; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Pyridines; Radioligand Assay; Receptors, CXCR4 | 2008 |
Ligand-guided optimization of CXCR4 homology models for virtual screening using a multiple chemotype approach.
Topics: Aminoquinolines; Artificial Intelligence; Benzimidazoles; Benzylamines; Binding Sites; Butylamines; Computer Simulation; Crystallography, X-Ray; Cyclams; Drug Design; Heterocyclic Compounds; Heterocyclic Compounds, 1-Ring; Humans; Ligands; Models, Molecular; Protein Binding; Pyridines; Receptors, Adrenergic, beta-2; Receptors, CXCR4; Sequence Alignment; Sequence Homology, Amino Acid; Structural Homology, Protein; Structure-Activity Relationship | 2010 |
Combination of drug therapy in acute lymphoblastic leukemia with a CXCR4 antagonist.
Topics: Aminoquinolines; Animals; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Benzylamines; Butylamines; Cell Movement; Chemokine CXCL12; Cyclams; Heterocyclic Compounds; Heterocyclic Compounds, 1-Ring; Humans; Mice; Mice, Inbred C57BL; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptors, CXCR4; Signal Transduction; Vincristine | 2011 |
Biased action of the CXCR4-targeting drug plerixafor is essential for its superior hematopoietic stem cell mobilization.
Topics: Aminoquinolines; Animals; Benzimidazoles; Benzylamines; beta-Arrestins; Butylamines; Cell Line, Tumor; Chlorocebus aethiops; COS Cells; Cyclams; Drug Delivery Systems; Female; Granulocyte Colony-Stimulating Factor; HEK293 Cells; Hematopoietic Stem Cell Mobilization; Hematopoietic Stem Cells; Humans; Mice; Mice, Inbred C57BL; Pharmaceutical Preparations; Receptors, CXCR3; Receptors, CXCR4 | 2021 |