pleiocarpamine has been researched along with sarpagine* in 2 studies
2 other study(ies) available for pleiocarpamine and sarpagine
| Article | Year |
|---|---|
Oxidized derivatives of macroline, sarpagine, and pleiocarpamine alkaloids from Alstonia angustifolia.
A total of 20 new indole alkaloids comprising mainly oxidized derivatives of macroline- (including alstofonidine, a macroline indole incorporating a butyrolactone ring-F), pleiocarpamine-, and sarpagine-type alkaloids were isolated from the bark and leaf extracts of Alstonia angustifolia. The structures and relative configurations of these alkaloids were determined using NMR and MS analyses and in some instances confirmed by X-ray diffraction analyses. Alkaloids 3, 7, 35, and 41 showed moderate to weak activity, while 21 showed strong activity in reversing multidrug resistance in vincristine-resistant KB cells. Topics: Alkaloids; Alstonia; Crystallography, X-Ray; Humans; Indole Alkaloids; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Oxindoles; Plant Leaves; Vincristine | 2014 |
Macroline-sarpagine and macroline-pleiocarpamine bisindole alkaloids from Alstonia angustifolia.
Nine bisindole alkaloids, comprising four belonging to the macroline-sarpagine group, and five belonging to the macroline-pleiocarpamine group, were isolated from the stem-bark extracts of Alstonia angustifolia (Apocynacea). Their structures were established using NMR and MS analyses. Topics: Alkaloids; Alstonia; Indole Alkaloids; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Oxindoles | 2013 |