Compounds > pleconaril

pleconaril and pirodavir

pleconaril has been researched along with pirodavir in 12 studies

Research

Studies (12)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	4 (33.33)	29.6817
2010's	8 (66.67)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Batugo, MR; Brown, EL; Chen, L; Dragovich, PS; Ferre, RA; Fuhrman, SA; Gleeson, JP; Guzman, MC; Hendrickson, TF; Kosa, MB; Lee, CA; Liu, B; Maldonado, FC; Matthews, DA; Meador, JW; Patick, AK; Prins, TJ; Sakata, SK; Tuntland, T; Worland, ST; Zalman, LS; Zhou, R	1
Barnard, DL; Brown, RN; Cameron, R; Chalmers, DK; Hamilton, S; Jin, B; Krippner, GY; Luttick, A; McConnell, DB; Reece, PA; Ryan, J; Sidwell, RW; Stanislawski, PC; Tucker, SP; Watson, KG; Wu, WY	1
Batugo, MR; Borer, BC; Brown, EL; Chen, L; Dovalsantos, EZ; Dragovich, PS; Ferre, RA; Fuhrman, SA; Gleeson, JP; Guo, M; Guzman, MC; Hua, Y; Johnson, TO; Kosa, MB; Lee, CA; Lee, S; Liese, A; Liu, B; Liu, J; Luu, HT; Maldonado, FC; Matthews, DA; McGee, K; Meador, JW; Mohajeri, M; Moran, T; Nayyar, NK; Patick, AK; Prins, TJ; Rejto, PA; Rose, PW; Sakata, SK; Tao, J; Tuntland, T; Wu, EY; Wu, ZP; Zalman, LS; Zhou, R	1
Brown, RN; Cameron, R; Chalmers, DK; Hamilton, S; Krippner, GY; Luttick, A; McConnell, DB; Nearn, R; Stanislawski, PC; Tucker, SP; Watson, KG	1
Gao, D; Gong, Z; Li, S; Sun, T; Wang, H; Xiao, J; Yan, H; Zhang, X	1
Cook, A; Jenkinson, L; King, S; MacDonald, C; McCrae, C; Morley, A; Phillips, T; Tomkinson, N; Unitt, J; Weaver, R	1
Feil, SC; Hamilton, S; Krippner, GY; Lin, B; Luttick, A; McConnell, DB; Morton, CJ; Nearn, R; Parker, MW; Ryan, J; Stanislawski, PC; Tucker, SP; Watson, KG	1
Bianco, G; Caboni, P; Cottiglia, F; Distinto, S; Floris, C; Fois, B; Maccioni, E; Marras, L; Meleddu, R; Melis, C; Pompei, R; Sonar, VP	1
Aguayo, E; Birkus, G; Cihlar, T; Jordan, R; Lee, G; Mello, C; Rodriguez, M	1
Bernard, A; Cabiddu, MG; Lacroix, C; Leyssen, P; Neyts, J; Pompei, R	1
Angius, F; Coluccia, A; Laconi, S; Lacroix, C; Leyssen, P; Neyts, J; Pompei, R; Silvestri, R	1
Day, CW; Evans, WJ; Nicolaou, KC; Smee, DF; Tarbet, EB	1

Other Studies

12 other study(ies) available for pleconaril and pirodavir

Article	Year
Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 6. Structure-activity studies of orally bioavailable, 2-pyridone-containing peptidomimetics. Journal of medicinal chemistry, 2002, Apr-11, Volume: 45, Issue:8 Topics: 3C Viral Proteases; Administration, Oral; Animals; Antiviral Agents; Biological Availability; Crystallography, X-Ray; Cysteine Endopeptidases; Dogs; Drug Stability; Humans; In Vitro Techniques; Ligands; Microsomes, Liver; Models, Molecular; Molecular Mimicry; Peptides; Protease Inhibitors; Protein Binding; Pyridones; Rhinovirus; Structure-Activity Relationship; Viral Proteins	2002
An orally bioavailable oxime ether capsid binder with potent activity against human rhinovirus. Journal of medicinal chemistry, 2003, Jul-17, Volume: 46, Issue:15 Topics: Administration, Oral; Animals; Antiviral Agents; Biological Availability; Capsid; Cell Line; Ethers; Female; Humans; Male; Mice; Oximes; Piperidines; Protein Binding; Pyridazines; Rats; Rhinovirus; Structure-Activity Relationship	2003
Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 8. Pharmacological optimization of orally bioavailable 2-pyridone-containing peptidomimetics. Journal of medicinal chemistry, 2003, Oct-09, Volume: 46, Issue:21 Topics: 3C Viral Proteases; Animals; Antiviral Agents; Biological Availability; Blood Proteins; Caco-2 Cells; Cysteine Endopeptidases; Dogs; Drug Design; Half-Life; Hepatocytes; Humans; In Vitro Techniques; Indicators and Reagents; Macaca fascicularis; Magnetic Resonance Spectroscopy; Male; Microsomes, Liver; Protease Inhibitors; Protein Binding; Pyridones; Rhinovirus; Solubility; Structure-Activity Relationship; Viral Proteins	2003
2-Ethoxybenzoxazole as a bioisosteric replacement of an ethyl benzoate group in a human rhinovirus (HRV) capsid binder. Bioorganic & medicinal chemistry letters, 2005, Apr-15, Volume: 15, Issue:8 Topics: Benzoates; Benzoxazoles; Capsid Proteins; Humans; Protein Binding; Rhinovirus; Stereoisomerism	2005
Pharmacophore-based design, synthesis, and biological evaluation of novel chloro-pyridazine piperazines as human rhinovirus (HRV-3) inhibitors. Bioorganic & medicinal chemistry letters, 2011, Feb-01, Volume: 21, Issue:3 Topics: Antiviral Agents; Binding Sites; Computer Simulation; Drug Design; Humans; Models, Chemical; Models, Molecular; Piperazines; Pyridazines; Rhinovirus; Viral Proteins	2011
Effect of lipophilicity modulation on inhibition of human rhinovirus capsid binders. Bioorganic & medicinal chemistry letters, 2011, Oct-15, Volume: 21, Issue:20 Topics: Animals; Antiviral Agents; Capsid; Capsid Proteins; Humans; Microsomes; Picornaviridae Infections; Protein Binding; Pyridazines; Rats; Rats, Sprague-Dawley; Rhinovirus; Structure-Activity Relationship	2011
An Orally Available 3-Ethoxybenzisoxazole Capsid Binder with Clinical Activity against Human Rhinovirus. ACS medicinal chemistry letters, 2012, Apr-12, Volume: 3, Issue:4 Topics:	2012
Phenylpropenoids from Bupleurum fruticosum as Anti-Human Rhinovirus Species A Selective Capsid Binders. Journal of natural products, 2017, 10-27, Volume: 80, Issue:10 Topics: Antiviral Agents; Bupleurum; Capsid; Enterovirus; HeLa Cells; Humans; Models, Molecular; Molecular Structure; Monoterpenes; Phenylpropionates; Plant Leaves; Rhinovirus; Structure-Activity Relationship; Virus Replication	2017
Multiple classes of antiviral agents exhibit in vitro activity against human rhinovirus type C. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:3 Topics: Antiviral Agents; Common Cold; Dose-Response Relationship, Drug; HeLa Cells; Humans; In Vitro Techniques; Isoxazoles; Oxadiazoles; Oxazoles; Phenylalanine; Piperidines; Pyridazines; Pyrrolidinones; Replicon; Rhinovirus; RNA, Viral; Tubercidin; Valine; Virus Replication	2014
Exploration of the anti-enterovirus activity of a series of pleconaril/pirodavir-like compounds. Antiviral chemistry & chemotherapy, 2015, Volume: 24, Issue:2 Topics: Antiviral Agents; Dose-Response Relationship, Drug; Enterovirus; Microbial Sensitivity Tests; Oxadiazoles; Oxazoles; Piperidines; Pyridazines; Structure-Activity Relationship	2015
In vitro characterisation of a pleconaril/pirodavir-like compound with potent activity against rhinoviruses. Virology journal, 2015, Jul-14, Volume: 12 Topics: Antiviral Agents; Capsid Proteins; Humans; Microbial Sensitivity Tests; Oxadiazoles; Oxazoles; Piperidines; Protein Binding; Pyridazines; Rhinovirus	2015
Susceptibilities of enterovirus D68, enterovirus 71, and rhinovirus 87 strains to various antiviral compounds. Antiviral research, 2016, Volume: 131 Topics: A549 Cells; Antimetabolites; Antiviral Agents; Benzimidazoles; Enterovirus A, Human; Enterovirus D, Human; Guanine; HeLa Cells; Humans; Oxadiazoles; Oxazoles; Oximes; Picornaviridae; Piperazines; Piperidines; Pyridazines; Rhabdomyosarcoma; Rhinovirus; Ribavirin; Sulfonamides	2016