Page last updated: 2024-08-22

platinum and rucaparib

platinum has been researched along with rucaparib in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (22.22)24.3611
2020's7 (77.78)2.80

Authors

AuthorsStudies
Bierbach, U; Ding, S1
Allen, AR; Bell-McGuinn, KM; Brenton, JD; Coleman, RL; Cragun, JM; Floquet, A; Giordano, H; Goble, S; Harding, TC; Harrell, MI; Isaacson, J; Kaufmann, SH; Konecny, GE; Kristeleit, RS; Leary, A; Lin, KK; Ma, L; Maloney, L; Mann, E; McNeish, IA; O'Malley, DM; Oaknin, A; Oza, AM; Raponi, M; Ray-Coquard, I; Rolfe, L; Scott, CL; Sun, J; Swisher, EM; Tinker, AV; Yelensky, R1
Tomao, F; Tomao, S; Vici, P1
Aghajanian, C; Armstrong, DK; Banerjee, S; Cameron, T; Clamp, AR; Coleman, RL; Colombo, N; Dean, A; Fong, PC; Gancedo, MA; García-Donas, J; Goble, S; Goh, JC; Holloway, RW; Leary, A; Ledermann, JA; Lorusso, D; Maloney, L; O'Malley, DM; Oaknin, A; Oza, AM; Scambia, G; Swisher, EM; Weberpals, JI1
Aghajanian, C; Beltman, J; Brenton, JD; Castro, C; Chen, LM; Coleman, RL; Goble, S; Green, M; Harding, T; Konecny, GE; Kristeleit, RS; Leary, A; Lin, KK; Ma, L; Maloney, L; McNeish, IA; O'Malley, DM; Oaknin, A; Oza, AM; Provencher, D; Ray-Coquard, I; Shapira-Frommer, R; Simmons, AD; Swisher, EM; Tinker, AV; Xiao, JJ1
Aghajanian, C; Chambers, SK; Chen, LM; Coleman, RL; Dobrovic, A; Dominy, E; Dorigo, O; Elvin, JA; Ghatage, P; Giordano, H; Goble, S; Harding, T; Kaufmann, SH; Konecny, GE; Kristeleit, RS; Kwan, TT; Leary, A; Lin, DI; Lin, KK; Ma, L; Maloney, L; McNeish, IA; Musafer, A; O'Malley, DM; Oaknin, A; Oza, AM; Provencher, D; Ray-Coquard, I; Scott, CL; Swisher, EM; Tinker, AV; Vo, LT; Wahner Hendrickson, AE; Welch, S1
Cancanelli, L; Chiumente, M; Di Spazio, L; Mengato, D; Messori, A; Rivano, M1
Barber, J; Birtle, AJ; Brock, S; Crabb, SJ; Dempsey, L; Enting, D; Faust, G; Frew, J; Gale, J; Hinsley, S; Hussain, S; Jones, RJ; Lees, K; McGovern, U; Parikh, O; Powles, T; Ratnayake, G; Song, Y; Soulis, E; Sundar, S; Trevethan, A1
Balmaña, J; Banerjee, S; Borrow, J; Burris, HA; Chen, LM; Domchek, SM; Drew, Y; Glasspool, RM; Goble, S; Kristeleit, RS; Lin, KK; Maloney, L; Oza, AM; Patel, MR; Safra, T; Shapira-Frommer, R1

Trials

4 trial(s) available for platinum and rucaparib

ArticleYear
Rucaparib in relapsed, platinum-sensitive high-grade ovarian carcinoma (ARIEL2 Part 1): an international, multicentre, open-label, phase 2 trial.
    The Lancet. Oncology, 2017, Volume: 18, Issue:1

    Topics: Aged; Antineoplastic Agents; BRCA1 Protein; BRCA2 Protein; Carcinoma, Ovarian Epithelial; Drug Resistance, Neoplasm; Fallopian Tube Neoplasms; Female; Follow-Up Studies; Germ-Line Mutation; Humans; Indoles; International Agencies; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Peritoneal Neoplasms; Platinum; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Prognosis; Prospective Studies; Salvage Therapy; Survival Rate

2017
Molecular and clinical determinants of response and resistance to rucaparib for recurrent ovarian cancer treatment in ARIEL2 (Parts 1 and 2).
    Nature communications, 2021, 05-03, Volume: 12, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; BRCA1 Protein; BRCA2 Protein; Carcinoma, Ovarian Epithelial; DNA Methylation; DNA-Binding Proteins; Female; Humans; Indoles; Middle Aged; Neoplasm Recurrence, Local; Ovarian Neoplasms; Platinum; Poly(ADP-ribose) Polymerase Inhibitors; Promoter Regions, Genetic

2021
A Randomized, Double-Blind, Biomarker-Selected, Phase II Clinical Trial of Maintenance Poly ADP-Ribose Polymerase Inhibition With Rucaparib Following Chemotherapy for Metastatic Urothelial Carcinoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2023, 01-01, Volume: 41, Issue:1

    Topics: Adenosine Diphosphate Ribose; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Carcinoma, Transitional Cell; Double-Blind Method; Female; Humans; Maintenance Chemotherapy; Ovarian Neoplasms; Platinum; Poly(ADP-ribose) Polymerases; Urinary Bladder Neoplasms

2023
Efficacy and safety of rucaparib treatment in patients with BRCA-mutated, relapsed ovarian cancer: final results from Study 10.
    British journal of cancer, 2023, Volume: 128, Issue:2

    Topics: BRCA2 Protein; Carcinoma, Ovarian Epithelial; Female; Humans; Neoplasm Recurrence, Local; Ovarian Neoplasms; Platinum; Poly(ADP-ribose) Polymerase Inhibitors

2023

Other Studies

5 other study(ies) available for platinum and rucaparib

ArticleYear
Linker design for the modular assembly of multifunctional and targeted platinum(ii)-containing anticancer agents.
    Dalton transactions (Cambridge, England : 2003), 2016, Aug-16, Volume: 45, Issue:33

    Topics: Acridines; Amines; Antineoplastic Agents; Dendrimers; Indoles; Organophosphorus Compounds; Platinum; Quinazolines; Tamoxifen

2016
Expanding use of rucaparib as maintenance therapy in recurrent ovarian cancer: updates from the ARIEL3 trial.
    The Lancet. Oncology, 2020, Volume: 21, Issue:5

    Topics: Carcinoma, Ovarian Epithelial; Female; Humans; Indoles; Neoplasm Recurrence, Local; Ovarian Neoplasms; Platinum

2020
Rucaparib for patients with platinum-sensitive, recurrent ovarian carcinoma (ARIEL3): post-progression outcomes and updated safety results from a randomised, placebo-controlled, phase 3 trial.
    The Lancet. Oncology, 2020, Volume: 21, Issue:5

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Disease Progression; Double-Blind Method; Female; Humans; Indoles; Middle Aged; Neoplasm Recurrence, Local; Ovarian Neoplasms; Platinum; Poly(ADP-ribose) Polymerase Inhibitors; Progression-Free Survival; Treatment Outcome

2020
Population exposure-efficacy and exposure-safety analyses for rucaparib in patients with recurrent ovarian carcinoma from Study 10 and ARIEL2.
    Gynecologic oncology, 2021, Volume: 161, Issue:3

    Topics: Administration, Oral; Aged; Area Under Curve; BRCA1 Protein; Carcinoma, Ovarian Epithelial; Dose-Response Relationship, Drug; Female; Humans; Indoles; Middle Aged; Neoplasm Recurrence, Local; Ovarian Neoplasms; Platinum

2021
Indirect comparison of three PARP inhibitors (olaparib, niraparib, and rucaparib) as maintenance treatment in ovarian carcinoma patients responding to platinum therapy.
    International journal of clinical pharmacology and therapeutics, 2022, Volume: 60, Issue:8

    Topics: Carcinoma, Ovarian Epithelial; Female; Humans; Indazoles; Indoles; Ovarian Neoplasms; Phthalazines; Piperazines; Piperidines; Platinum; Poly(ADP-ribose) Polymerase Inhibitors

2022