Page last updated: 2024-08-22

platinum and pyrimidinones

platinum has been researched along with pyrimidinones in 7 studies

Research

Studies (7)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	3 (42.86)	24.3611
2020's	4 (57.14)	2.80

Authors

Authors	Studies
Celebi, M; Sentürk, Z; Sönmez, M; Yardim, Y	1
Brantley, SG; Cress, WD; Gray, JE; Haura, EB; Jhuraney, A; Kinose, F; Koomen, JM; Kroeger, JL; Monteiro, AN; Remily-Wood, E; Rix, L; Rix, U; Woods, NT; Wright, G	1
Barbie, DA; Humeniuk, R; Kawashima, J; Kelly, K; Koczywas, M; Kong, S; Spira, A	1
Ahn, JS; Ahn, MJ; Godin, RE; Hollingsworth, SJ; Jung, HA; Kim, HJ; Lee, SH; Mortimer, PGS; Park, K; Park, S; Park, WY; Shim, J; Smith, SA; Sun, JM	1
Blagden, SP; Nicum, S	1
Killock, D	1
Cadoo, KA; Chambers, SK; Chen, LM; Chmielecki, J; Cragun, JM; Geenen, JJJ; Ghamande, SA; Hamilton, EP; Jones, SF; Konecny, GE; Kumar, S; Lai, Z; Moore, KN; Mugundu, GM; Oza, AM; Plaxe, SC; Rodrigo Imedio, E; Spigel, DR; Spitz, DL; Troso-Sandoval, TA	1

Trials

2 trial(s) available for platinum and pyrimidinones

Article	Year
Phase 1B Study of Momelotinib Combined With Trametinib in Metastatic, Kirsten Rat Sarcoma Viral Oncogene Homolog-Mutated Non-Small-Cell Lung Cancer After Platinum-Based Chemotherapy Treatment Failure. Clinical lung cancer, 2018, Volume: 19, Issue:6 Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Carcinoma, Non-Small-Cell Lung; Female; Humans; Janus Kinases; Lung Neoplasms; Male; MAP Kinase Kinase 1; Middle Aged; Mutation; Neoplasm Metastasis; Platinum; Proto-Oncogene Proteins p21(ras); Pyridones; Pyrimidines; Pyrimidinones; Treatment Failure	2018
Biomarker-driven phase 2 umbrella trial study for patients with recurrent small cell lung cancer failing platinum-based chemotherapy. Cancer, 2020, 09-01, Volume: 126, Issue:17 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Biomarkers, Tumor; Cyclin-Dependent Kinase Inhibitor p16; Drug-Related Side Effects and Adverse Reactions; Female; Gene Amplification; Humans; Male; Middle Aged; Morpholines; Neoplasm Recurrence, Local; Platinum; Progression-Free Survival; Proto-Oncogene Proteins c-myc; Pyrazoles; Pyrimidines; Pyrimidinones; Rapamycin-Insensitive Companion of mTOR Protein; Small Cell Lung Carcinoma; Tumor Suppressor Protein p53	2020

Article

Year

Phase 1B Study of Momelotinib Combined With Trametinib in Metastatic, Kirsten Rat Sarcoma Viral Oncogene Homolog-Mutated Non-Small-Cell Lung Cancer After Platinum-Based Chemotherapy Treatment Failure.

Clinical lung cancer, 2018, Volume: 19, Issue:6

Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Carcinoma, Non-Small-Cell Lung; Female; Humans; Janus Kinases; Lung Neoplasms; Male; MAP Kinase Kinase 1; Middle Aged; Mutation; Neoplasm Metastasis; Platinum; Proto-Oncogene Proteins p21(ras); Pyridones; Pyrimidines; Pyrimidinones; Treatment Failure

2018

Biomarker-driven phase 2 umbrella trial study for patients with recurrent small cell lung cancer failing platinum-based chemotherapy.

Cancer, 2020, 09-01, Volume: 126, Issue:17

Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Biomarkers, Tumor; Cyclin-Dependent Kinase Inhibitor p16; Drug-Related Side Effects and Adverse Reactions; Female; Gene Amplification; Humans; Male; Middle Aged; Morpholines; Neoplasm Recurrence, Local; Platinum; Progression-Free Survival; Proto-Oncogene Proteins c-myc; Pyrazoles; Pyrimidines; Pyrimidinones; Rapamycin-Insensitive Companion of mTOR Protein; Small Cell Lung Carcinoma; Tumor Suppressor Protein p53

2020

Other Studies

5 other study(ies) available for platinum and pyrimidinones

Article	Year
Palladium(II) and platinum(II) complexes of a symmetric Schiff base derived from 2,6,diformyl-4-methylphenol with N-aminopyrimidine: synthesis, characterization and detection of DNA interaction by voltammetry. European journal of medicinal chemistry, 2010, Volume: 45, Issue:9 Topics: Cresols; DNA; Electrochemistry; Organoplatinum Compounds; Palladium; Platinum; Pyrimidinones; Schiff Bases	2010
PAXIP1 Potentiates the Combination of WEE1 Inhibitor AZD1775 and Platinum Agents in Lung Cancer. Molecular cancer therapeutics, 2016, Volume: 15, Issue:7 Topics: Antineoplastic Agents; Apoptosis; Carrier Proteins; CDC2 Protein Kinase; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cluster Analysis; Cyclin-Dependent Kinases; DNA-Binding Proteins; Drug Discovery; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Mitosis; Nuclear Proteins; Phosphorylation; Platinum; Protein Binding; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrazoles; Pyrimidines; Pyrimidinones	2016
A source of hope for platinum-resistant ovarian cancer? Lancet (London, England), 2021, 01-23, Volume: 397, Issue:10271 Topics: Deoxycytidine; Double-Blind Method; Female; Gemcitabine; Humans; Ovarian Neoplasms; Platinum; Pyrazoles; Pyrimidinones	2021
WEE1 inhibition after platinum resistance. Nature reviews. Clinical oncology, 2021, Volume: 18, Issue:4 Topics: Cell Cycle Proteins; Deoxycytidine; Double-Blind Method; Female; Gemcitabine; Humans; Ovarian Neoplasms; Platinum; Protein-Tyrosine Kinases; Pyrazoles; Pyrimidinones	2021
Adavosertib with Chemotherapy in Patients with Primary Platinum-Resistant Ovarian, Fallopian Tube, or Peritoneal Cancer: An Open-Label, Four-Arm, Phase II Study. Clinical cancer research : an official journal of the American Association for Cancer Research, 2022, 01-01, Volume: 28, Issue:1 Topics: Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Fallopian Tubes; Female; Humans; Ovarian Neoplasms; Paclitaxel; Platinum; Pyrazoles; Pyrimidinones	2022