plantamajoside and hippuric-acid

plantamajoside has been researched along with hippuric-acid* in 1 studies

Other Studies

1 other study(ies) available for plantamajoside and hippuric-acid

ArticleYear
Bioguided isolation of angiotensin-converting enzyme inhibitors from the seeds of Plantago asiatica L.
    Phytotherapy research : PTR, 2010, Volume: 24, Issue:7

    Ethanolic extract of the seeds of Plantago asiatica L. showed significant inhibitory activity of angiotensin-converting enzyme (ACE) determined by monitoring the transformation from a substrate hippuryl-histidyl-leucine (HHL) to the product hippuric acid (HA) in vitro using an UPLC-MS method. The bioguided fractionation of the extract resulted in the isolation of four ACE inhibitory active phenylpropanoid glycosides acteoside, isoacteoside, plantainoside D, and plantamajoside with IC(50) values of 2.69 mM, 2.46 mM, 2.17 mM, and 2.47 mM, respectively. Their structures were elucidated through the analysis of NMR, UV, IR and MS data. Our study is the first demonstration that Plantago asiatica L. and its major constituents have ACE inhibitory activity in vitro. It is assumed that the identified compounds contribute to the angiotensin-converting enzyme-inhibitory activity of the extract.

    Topics: Angiotensin-Converting Enzyme Inhibitors; Catechols; Glucosides; Glycosides; Hippurates; Inhibitory Concentration 50; Molecular Structure; Oligopeptides; Plant Extracts; Plantago; Seeds

2010