Page last updated: 2024-08-25

plafibride and clofibrate

plafibride has been researched along with clofibrate in 31 studies

Research

Studies (31)

Timeframe	Studies, this research(%)	All Research%
pre-1990	31 (100.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bruseghini, L; Vilageliu, J	1
Jover, E; López, IM; Rodriguez, F	1
Esteva de Antonio, I; Soringer Escofet, FJ	1
Joven, J	1
Basi, N; Bermejo, P; Bruseghini, L; Freixes, J; Giráldez, A; Vilageliu, J	1
Díez, MM; Fernández, A; Gil, M; Lasierra, J; Velázquez, E; Viladés, E	1
de la Sierra, L; Gesto Castromil, R; Lázaro Campillo, T; Moreno, R; Pujadas, J; Villafana, W	1
Badimón, JJ; Cánovas, M; Padró, T; Vidal, M; Villaverde, CA	1
Calatayud, JM	1
Bruseghini, L; Freixes, J; Vilageliu, J	2
Gómez, JM; Morató, J; Soler, J; Vinzia, C	1
Artús, JJ; Bruseghini, L; Freixes, J; Ribalta, JM; Roma, E; Salvador, L; Vilageliu, J	1
Bargalló, MA; Basi, N; Beascoa, E; Bermejo, P; Bruseghini, L; Gimenez, F; Giráldez, A; Gras, J; Llenas, J; Zapatero, J	1
Jones, E; Richold, M	1
Olivella, J; Vicens, B	1
del Rio, A; Ferreira, IJ; González-Viejo, N; Vicens, B	1
DiBlasio, P; Gasparini Casari, M; Palmieri, B; Zirilli, E	1
Casasnovas Lenguas, JA; Cornudella Lacasa, R; del Río Ligorit, A; Ferreira Montero, IJ; Gutiérrez Martín, M	1
Ribalta, JM; Ristol, P; Torres, A	1
Bagaria, A; Bruseghini, L; Vilageliu, J	1
Bruseghini, L; Ribalta, JM; Torres, A; Vilageliu, J; Zapatero, D	1
Bruseghini, L; Sanfeliu, C; Zapatero, J	3
Basi, N; Bruseghini, L; Sanfeliu, C; Vilageliu, J; Zapatero, J	1
Bruseghini, L; Dalmau, J; Vicens, B; Zapatero, J	2
Bruseghini, L; Conti, F; Santaniello, E; Vilageliu, J	1
Bracons, R; Bruseghini, L; Demichelis Genesio, MA; Vicens, B; Zapatero, J	1

Trials

7 trial(s) available for plafibride and clofibrate

Article	Year
Plafibride: clinical trial of a new platelet antiaggregating agent. Arzneimittel-Forschung, 1981, Volume: 31, Issue:10a Topics: Adenosine Diphosphate; Aged; Cerebrovascular Disorders; Clinical Trials as Topic; Clofibrate; Clofibric Acid; Dipyridamole; Double-Blind Method; Humans; Middle Aged; Platelet Aggregation; Time Factors	1981
Double-blind study on the activity of plafibride in the treatment of type IV hyperlipoproteinemia. Arzneimittel-Forschung, 1981, Volume: 31, Issue:10a Topics: Clinical Trials as Topic; Clofibrate; Clofibric Acid; Double-Blind Method; Female; Humans; Hyperlipoproteinemia Type IV; Hypolipidemic Agents; Lipids; Male; Middle Aged; Platelet Function Tests	1981
Clinical research into the hypolipemic and platelet antiaggregant activity of plafibride, Carried out in double-blind conditions and in comparison with clofibrate. Arzneimittel-Forschung, 1981, Volume: 31, Issue:10a Topics: Adenosine Diphosphate; Adult; Aged; Cholesterol; Clinical Trials as Topic; Clofibrate; Clofibric Acid; Double-Blind Method; Female; Humans; Hyperlipidemias; Hypolipidemic Agents; Lipids; Lipoproteins; Male; Middle Aged; Platelet Aggregation; Triglycerides	1981
[Controlled clinical trial of a new drug (plafibride) for the treatment of hyperlipoproteinemia type IV (author's transl)]. Medicina clinica, 1982, May-01, Volume: 78, Issue:9 Topics: Adult; Aged; Clinical Trials as Topic; Clofibrate; Clofibric Acid; Double-Blind Method; Female; Humans; Hyperlipoproteinemia Type IV; Lipids; Male; Middle Aged; Platelet Function Tests; Random Allocation	1982
Plafibride tolerance trial at increasing doses in healthy volunteers. Arzneimittel-Forschung, 1981, Volume: 31, Issue:10a Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Blood Cell Count; Blood Glucose; Clofibrate; Clofibric Acid; Double-Blind Method; Hemodynamics; Humans; Hypolipidemic Agents	1981
Plafibride tolerance trial in healthy volunteers. Arzneimittel-Forschung, 1981, Volume: 31, Issue:10a Topics: Adult; Aspirin; Clofibrate; Clofibric Acid; Double-Blind Method; Erythrocyte Count; Humans; Hypolipidemic Agents; Leukocyte Count; Lipids; Platelet Aggregation	1981
Clinical trials of plafibride in geriatric patients. Arzneimittel-Forschung, 1981, Volume: 31, Issue:10a Topics: Aged; Arteriosclerosis; Clofibrate; Clofibric Acid; Female; Humans; Hypolipidemic Agents; Lipids; Male; Middle Aged; Platelet Aggregation; Time Factors	1981

Other Studies

24 other study(ies) available for plafibride and clofibrate

Article	Year
[ITA 104, a product of antiplatelet aggregation activity]. Archivos de farmacologia y toxicologia, 1978, Volume: 4, Issue:1 Topics: Adenosine Diphosphate; Animals; Aspirin; Clofibrate; Clofibric Acid; Depression, Chemical; Dogs; Platelet Aggregation; Rats	1978
Plafibride treatment and serum lipids in hyperlipoproteinemias. Journal of medicine, 1987, Volume: 18, Issue:3-4 Topics: Adolescent; Adult; Blood Glucose; Cholesterol; Clofibrate; Clofibric Acid; Diet; Female; Humans; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type IV; Insulin; Male; Phosphatidylcholines; Triglycerides	1987
[Plafibride and vascular insufficiency of the lower limbs]. Medicina clinica, 1985, Apr-20, Volume: 84, Issue:15 Topics: Clofibrate; Clofibric Acid; Drug Evaluation; Humans; Intermittent Claudication	1985
[Plafibride--is it an effective drug as a hypolipemic agent?]. Medicina clinica, 1985, Apr-20, Volume: 84, Issue:15 Topics: Clofibrate; Clofibric Acid; Drug Evaluation; Humans; Hypolipidemic Agents; Intermittent Claudication	1985
Influence of plafibride, an antiplatelet and hypolipemic agent, on prostacyclin and thromboxane synthesis, 3',5'-cyclic AMP phosphodiesterase activity and serum clearance of a lipid emulsion. Arzneimittel-Forschung, 1981, Volume: 31, Issue:10a Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cattle; Clofibrate; Clofibric Acid; Cyclooxygenase Inhibitors; Depression, Chemical; Epoprostenol; Fat Emulsions, Intravenous; Hypolipidemic Agents; In Vitro Techniques; Kinetics; Lipids; Prostaglandins; Rats; Rats, Inbred Strains; Thromboxane A2; Thromboxanes	1981
[Evaluation of the effects of plafibride and lysine acetyl salicylate on the production of PGI2]. Sangre, 1983, Volume: 28, Issue:6 Topics: Animals; Aorta; Arteriosclerosis; Aspirin; Clofibrate; Clofibric Acid; Diet, Atherogenic; Epoprostenol; Lysine; Male; Platelet Aggregation; Rabbits	1983
[Therapy of vascular insufficiency of the legs with plafibride]. Medicina clinica, 1984, Dec-01, Volume: 83, Issue:18 Topics: Adult; Aged; Clofibrate; Clofibric Acid; Drug Tolerance; Humans; Hypolipidemic Agents; Intermittent Claudication; Leg; Male; Middle Aged	1984
Hypolipemic profile of plafibride in a model of experimental atherosclerosis. Methods and findings in experimental and clinical pharmacology, 1983, Volume: 5, Issue:9 Topics: Animals; Arteriosclerosis; Cholesterol; Cholesterol, HDL; Clofibrate; Clofibric Acid; Female; Hypolipidemic Agents; Lipoproteins, HDL; Rats; Rats, Inbred Strains; Triglycerides	1983
Favorable effects of the lipid-lowering and platelet antiaggregant Plafibride on the aging process of mice of the C57bl/6J strain. Methods and findings in experimental and clinical pharmacology, 1983, Volume: 5, Issue:10 Topics: Aging; Animal Feed; Animals; Body Weight; Clofibrate; Clofibric Acid; Hypolipidemic Agents; Lipofuscin; Liver; Male; Mice; Mice, Inbred C57BL; Organ Size; Platelet Aggregation	1983
Activity of plafibride on erythrocyte deformability. Arzneimittel-Forschung, 1983, Volume: 33, Issue:3 Topics: Adult; Animals; Clofibrate; Clofibric Acid; Dogs; Erythrocytes; Female; Humans; In Vitro Techniques; Male; Rabbits; Rats; Rats, Inbred Strains; Species Specificity	1983
[Plafibride treatment of hyperlipidemias type II and IV]. Medicina clinica, 1984, May-19, Volume: 82, Issue:19 Topics: Adult; Cholesterol; Clofibrate; Clofibric Acid; Female; Humans; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type IV; Hypolipidemic Agents; Male; Middle Aged; Triglycerides	1984
Synthesis and pharmacological evaluation of N'-morpholinomethylurea derivatives with platelet antiaggregant activity. Arzneimittel-Forschung, 1981, Volume: 31, Issue:10a Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Chemical Phenomena; Chemistry; Clofibrate; Clofibric Acid; Humans; Hypolipidemic Agents; In Vitro Techniques; Lethal Dose 50; Platelet Aggregation; Rats; Rats, Inbred Strains	1981
Platelet antiaggregant activity of plafibride ex vivo in rat, dog and rabbit. Arzneimittel-Forschung, 1981, Volume: 31, Issue:10a Topics: Adenosine Diphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Clofibrate; Clofibric Acid; Collagen; Dogs; Epinephrine; Female; In Vitro Techniques; Male; Platelet Aggregation; Rabbits; Rats; Rats, Inbred Strains; Species Specificity	1981
Pharmacological activities and side effects of plafibride. Arzneimittel-Forschung, 1981, Volume: 31, Issue:10a Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Autonomic Nervous System; Body Temperature; Cardiovascular System; Central Nervous System; Clofibrate; Clofibric Acid; Digestive System; Dogs; Female; Guinea Pigs; Male; Mice; Peripheral Nerves; Rabbits; Rats; Respiration	1981
Bacterial mutation test on plafibride. Arzneimittel-Forschung, 1981, Volume: 31, Issue:10a Topics: Animals; Clofibrate; Clofibric Acid; In Vitro Techniques; Mutagenicity Tests; Mutagens; Rats; Salmonella typhimurium	1981
Plafibride (ITA 104). Arzneimittel-Forschung, 1981, Volume: 31, Issue:10a Topics: Clofibrate; Clofibric Acid; Humans	1981
Physico-chemical and analytical studies on plafibride. Arzneimittel-Forschung, 1981, Volume: 31, Issue:10a Topics: Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Clofibrate; Clofibric Acid; Drug Stability; Magnetic Resonance Spectroscopy; Mass Spectrometry; Potentiometry; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet	1981
Hypolipemic activity of plafibride. Arzneimittel-Forschung, 1981, Volume: 31, Issue:10a Topics: Animals; Cholesterol; Clofibrate; Clofibric Acid; Dogs; Fatty Acids, Nonesterified; Hypolipidemic Agents; Lipoproteins; Male; Mice; Mice, Inbred Strains; Polyethylene Glycols; Rats; Rats, Inbred Strains; Triglycerides	1981
Pharmacokinetic approach of plafibride in rat. Arzneimittel-Forschung, 1981, Volume: 31, Issue:10a Topics: Animals; Clofibrate; Clofibric Acid; Feces; Hypolipidemic Agents; Kinetics; Male; Protein Binding; Rats; Rats, Inbred Strains	1981
Toxicological studies of plafibride. Part 1: Acute toxicity and its determination after several administrations of plafibride. Arzneimittel-Forschung, 1981, Volume: 31, Issue:10a Topics: Administration, Oral; Animals; Clofibrate; Clofibric Acid; Cricetinae; Female; Guinea Pigs; Injections, Intraperitoneal; Injections, Intravenous; Lethal Dose 50; Male; Mice; Mice, Inbred C57BL; Rats; Rats, Inbred Strains; Species Specificity	1981
Toxicological studies of plafibride. Part 2: Subacute and subchronic toxicity in rats and chronic toxicity in dogs. Arzneimittel-Forschung, 1981, Volume: 31, Issue:10a Topics: Animals; Blood Cell Count; Body Weight; Clofibrate; Clofibric Acid; Dogs; Female; Male; Organ Size; Rats; Rats, Inbred Strains; Species Specificity; Time Factors	1981
Toxicological studies of plafibride. Part 3: Study of teratogenic activity in rats and rabbits. Arzneimittel-Forschung, 1981, Volume: 31, Issue:10a Topics: Animals; Clofibrate; Clofibric Acid; Female; Fetus; Pregnancy; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Teratogens	1981
Toxicological studies of plafibride. Part 4: Interaction of plafibride with other drugs. Arzneimittel-Forschung, 1981, Volume: 31, Issue:10a Topics: Animals; Blepharoptosis; Blood Pressure; Body Temperature; Clofibrate; Clofibric Acid; Dogs; Drug Interactions; Mice; Rats; Rats, Inbred Strains; Reserpine; Warfarin	1981
Bioavailability of plafibride in healthy volunteers. Arzneimittel-Forschung, 1981, Volume: 31, Issue:10a Topics: Adult; Biological Availability; Clofibrate; Clofibric Acid; Female; Humans; Male; Platelet Aggregation	1981