pk 9084 has been researched along with gamma-aminobutyric acid in 7 studies
*gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system. [MeSH]
*gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system. [MeSH]
| Studies (pk 9084) | Trials (pk 9084) | Recent Studies (post-2010) (pk 9084) | Studies (gamma-aminobutyric acid) | Trials (gamma-aminobutyric acid) | Recent Studies (post-2010) (gamma-aminobutyric acid) |
|---|---|---|---|---|---|
| 17 | 0 | 0 | 40,215 | 1,423 | 9,631 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| De Deyn, PP; Macdonald, RL | 1 |
| Gee, KW | 1 |
| Le Fur, G | 1 |
| Keane, PE; Morre, M; Simiand, J | 1 |
| Brinton, RE; Gee, KW; Yamamura, HI | 1 |
| Broekkamp, CL; Le Pichon, M; Lloyd, KG | 1 |
| File, SE; Simmonds, MA | 1 |
7 other study(ies) available for pk 9084 and gamma-aminobutyric acid
| Article | Year |
|---|---|
Effects of non-sedative anxiolytic drugs on responses to GABA and on diazepam-induced enhancement of these responses on mouse neurones in cell culture.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Buspirone; Carbolines; Cells, Cultured; Convulsants; Diazepam; Electrophysiology; Flumazenil; gamma-Aminobutyric Acid; Mice; Neurons; Pyrazoles; Quinolines; Spinal Cord | 1988 |
Phenylquinolines PK 8165 and PK 9084 allosterically modulate [35S]t-butylbicyclophosphorothionate binding to a chloride ionophore in rat brain via a novel Ro5 4864 binding site.
Topics: Animals; Anticonvulsants; Benzodiazepinones; Bicuculline; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Convulsants; gamma-Aminobutyric Acid; Kinetics; Male; Quinolines; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1987 |
[Anxiety receptors: new pharmacological approach (author's transl)].
Topics: Animals; Anti-Anxiety Agents; Anxiety Disorders; Binding, Competitive; Brain; Chlordiazepoxide; Chlorides; Diazepam; gamma-Aminobutyric Acid; Humans; Quinolines; Receptors, Cell Surface; Receptors, Drug; Receptors, GABA-A; Seizures | 1982 |
The quinolines PK 8165 and PK 9084 possess benzodiazepine-like activity in vitro but not in vivo.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Brain; Diazepam; Flunitrazepam; gamma-Aminobutyric Acid; In Vitro Techniques; Mice; Quinolines; Rats; Receptors, Cell Surface; Receptors, GABA-A | 1984 |
PK 8165 and PK 9084, two quinoline derivatives with anxiolytic properties, antagonize the anticonvulsant effects of diazepam.
Topics: Animals; Anticonvulsants; Benzodiazepines; Bicuculline; Brain; Diazepam; Drug Antagonism; Flunitrazepam; gamma-Aminobutyric Acid; Male; Mice; Quinolines; Receptors, Cell Surface; Receptors, GABA-A; Seizures | 1983 |
The comparative effects of benzodiazepines, progabide and PK 9084 on acquisition of passive avoidance in mice.
Topics: Animals; Avoidance Learning; Benzodiazepines; gamma-Aminobutyric Acid; Male; Mice; Motor Activity; Quinolines | 1984 |
Interactions of two phenylquinolines with picrotoxin and benzodiazepines in vivo and in vitro.
Topics: Animals; Anticonvulsants; Benzodiazepines; Drug Interactions; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Myoclonus; Pentylenetetrazole; Picrotoxin; Quinolines; Rats; Rats, Inbred Strains; Seizures | 1984 |