pixantrone has been researched along with formaldehyde in 6 studies
Studies (pixantrone) | Trials (pixantrone) | Recent Studies (post-2010) (pixantrone) | Studies (formaldehyde) | Trials (formaldehyde) | Recent Studies (post-2010) (formaldehyde) |
---|---|---|---|---|---|
92 | 16 | 59 | 22,546 | 243 | 5,887 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 3 (50.00) | 29.6817 |
2010's | 2 (33.33) | 24.3611 |
2020's | 1 (16.67) | 2.80 |
Authors | Studies |
---|---|
Cutts, SM; Evison, BJ; Mansour, OC; Menta, E; Phillips, DR | 1 |
Chiu, F; Cutts, SM; Evison, BJ; Pezzoni, G; Phillips, DR | 1 |
Bilardi, RA; Chiu, FC; Cutts, SM; Evison, BJ; Pezzoni, G; Phillips, DR | 1 |
Bilardi, RA; Buck, DP; Collins, JG; Cutts, SM; Evison, BJ; Mansour, OC; Nudelman, A; Phillips, DR; Rephaeli, A; Sleebs, BE; Watson, KG | 1 |
Ankers, EA; Brownlee, RTC; Cutts, SM; Evison, BJ; Phillips, DR | 1 |
Cutts, SM; Evison, BJ; Mansour, OC; Nudelman, A; Phillips, DR; Rephaeli, A | 1 |
6 other study(ies) available for pixantrone and formaldehyde
Article | Year |
---|---|
Pixantrone can be activated by formaldehyde to generate a potent DNA adduct forming agent.
Topics: Antineoplastic Agents; DNA Adducts; Formaldehyde; Hydrogen-Ion Concentration; Isoquinolines; Kinetics; Temperature | 2007 |
Formaldehyde-activated Pixantrone is a monofunctional DNA alkylator that binds selectively to CpG and CpA doublets.
Topics: Adenine Nucleotides; Alkylating Agents; Antineoplastic Agents; Base Sequence; CpG Islands; DNA Adducts; DNA Methylation; Formaldehyde; Isoquinolines; Molecular Structure | 2008 |
CpG methylation potentiates pixantrone and doxorubicin-induced DNA damage and is a marker of drug sensitivity.
Topics: 5-Methylcytosine; Antibiotics, Antineoplastic; Cell Line, Tumor; CpG Islands; DNA Adducts; DNA Damage; DNA Methylation; DNA-Cytosine Methylases; Doxorubicin; Formaldehyde; Humans; Isoquinolines; Mass Spectrometry | 2009 |
New anthracenedione derivatives with improved biological activity by virtue of stable drug-DNA adduct formation.
Topics: Anthraquinones; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Proliferation; DNA Adducts; DNA-Directed RNA Polymerases; Drug Screening Assays, Antitumor; Escherichia coli Proteins; Formaldehyde; Humans; Hydrogen-Ion Concentration; Isoquinolines; Mitoxantrone; Models, Molecular; Prodrugs; Structure-Activity Relationship; Transcription, Genetic | 2010 |
Design, synthesis, and DNA sequence selectivity of formaldehyde-mediated DNA-adducts of the novel N-(4-aminobutyl) acridine-4-carboxamide.
Topics: Acridines; CpG Islands; Disinfectants; DNA Adducts; Drug Design; Formaldehyde; Isoquinolines; Models, Molecular; Molecular Structure; Topoisomerase II Inhibitors | 2014 |
An evaluation of the interaction of pixantrone with formaldehyde-releasing drugs in cancer cells.
Topics: DNA Adducts; DNA Topoisomerases, Type II; Formaldehyde; Humans; Isoquinolines; Neoplasms; Prodrugs | 2022 |