pivaloylcarnitine has been researched along with pivalic acid in 18 studies
| Studies (pivaloylcarnitine) | Trials (pivaloylcarnitine) | Recent Studies (post-2010) (pivaloylcarnitine) | Studies (pivalic acid) | Trials (pivalic acid) | Recent Studies (post-2010) (pivalic acid) |
|---|---|---|---|---|---|
| 26 | 1 | 7 | 112 | 2 | 29 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.56) | 18.7374 |
| 1990's | 8 (44.44) | 18.2507 |
| 2000's | 6 (33.33) | 29.6817 |
| 2010's | 3 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hashimoto, H; Konishi, M | 1 |
| Konishi, M; Shimizu, K; Totsuka, K; Yamamoto, S | 1 |
| Matsuno, S; Mizojiri, K; Nakashima, M; Oguma, T; Uematsu, T; Yamamoto, S; Yoshida, T | 1 |
| Bieber, LL; Kerner, J; Melegh, B | 1 |
| Brørs, O; Bøhmer, T; Diep, QN | 1 |
| Bøhmer, T; Diep, QN | 1 |
| Bøhmer, T; Diep, QN; Skrede, S | 1 |
| Chiba, S; Fujii, R; Meguro, H; Mori, A; Mori, T; Numazaki, K; Satoh, Y; Sunakawa, K; Terashima, I; Toyonaga, Y | 1 |
| Melegh, B; Sherry, AD; Sumegi, B | 1 |
| Fujigaki, M; Komiya, I; Nakayoshi, T; Okudaira, N; Sugiyama, Y | 1 |
| Brass, EP | 1 |
| Nakajima, Y; Nakamura, Y; Yamaguchi, T | 1 |
| Hasegawa, H; Norikura, R; Ohnishi, S; Okamura, N; Shimaoka, H | 1 |
| Baba, T; Hasegawa, H; Horie, K; Kanaoka, E; Norikura, R; Ohnishi, S; Okamura, N; Sakamoto, K; Sakamoto, S; Takahashi, K | 1 |
| Bodmer, M; Häussinger, D; Krähenbühl, S; Todesco, L; Vonwil, K | 1 |
| Boemer, F; de Halleux, V; Debray, FG; Kalenga, M; Schoos, R | 1 |
| Boemer, F; Dayaldasani, A; Rueda, I; Yahyaoui, R | 1 |
| Fuchigami, T; Ishige, M; Ishige, N; Nakazaki, K; Ogawa, E; Takahashi, S | 1 |
1 review(s) available for pivaloylcarnitine and pivalic acid
| Article | Year |
|---|---|
Pivalate-generating prodrugs and carnitine homeostasis in man.
Topics: Animals; Carnitine; Homeostasis; Humans; Pentanoic Acids; Prodrugs; Tissue Distribution | 2002 |
1 trial(s) available for pivaloylcarnitine and pivalic acid
| Article | Year |
|---|---|
Phase I clinical studies of S-1108: safety and pharmacokinetics in a multiple-administration study with special emphasis on the influence on carnitine body stores.
Topics: Adult; Carnitine; Cephalosporins; Drug Administration Schedule; Drug Evaluation; Humans; Male; Pentanoic Acids; Tablets | 1992 |
16 other study(ies) available for pivaloylcarnitine and pivalic acid
| Article | Year |
|---|---|
Determination of pivaloylcarnitine in human plasma and urine by high-performance liquid chromatography with fluorescence detection.
Topics: Calibration; Carnitine; Cephalosporins; Chromatography, High Pressure Liquid; Drug Stability; Humans; Pentanoic Acids; Prodrugs; Quinoxalines; Sensitivity and Specificity; Spectrometry, Fluorescence | 1992 |
Metabolism of S-1108, a new oral cephem antibiotic, and metabolic profiles of its metabolites in humans.
Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Carnitine; Cephalosporins; Humans; Male; Pentanoic Acids | 1992 |
Pivampicillin-promoted excretion of pivaloylcarnitine in humans.
Topics: Acetylcarnitine; Adolescent; Ampicillin; Carnitine; Child; Female; Humans; Kidney; Male; Pentanoic Acids; Pivampicillin | 1987 |
Formation of pivaloylcarnitine in isolated rat heart cells.
Topics: Acetylcarnitine; Animals; Betaine; Carnitine; Cells, Cultured; Kinetics; Myocardium; Pentanoic Acids; Pivampicillin; Rats; Rats, Wistar | 1995 |
Increased pivaloylcarnitine in the liver of the sodium pivalate treated rat exposed to clofibrate.
Topics: Adipose Tissue, Brown; Animals; Carnitine; Carnitine O-Acetyltransferase; Clofibrate; Heart; Liver; Male; Pentanoic Acids; Rats; Rats, Wistar; Triglycerides | 1995 |
Formation of pivaloylcarnitine in heart and brown adipose tissue in the rat.
Topics: Adipose Tissue, Brown; Animals; Carbon Radioisotopes; Carnitine; Chromatography, Gas; Isotope Labeling; Male; Myocardium; Pentanoic Acids; Rats; Rats, Wistar; Tissue Distribution | 1995 |
[Effect of cefditoren pivoxil on carnitine metabolism in pediatric patients].
Topics: Bacterial Infections; Carnitine; Cephalosporins; Child; Child, Preschool; Female; Humans; Infant; Male; Pentanoic Acids | 1993 |
Preferential elimination of pivalate with supplemental carnitine via formation of pivaloylcarnitine in man.
Topics: Adolescent; Carnitine; Child; Chromatography, Gas; Drug Interactions; Esters; Female; Humans; Magnetic Resonance Spectroscopy; Male; Pentanoic Acids; Pivampicillin | 1993 |
Up-regulation of carnitine transporters helps maintain tissue carnitine levels in carnitine deficiency induced by pivalic acid.
Topics: Animals; Carnitine; Carrier Proteins; Injections, Intra-Arterial; Injections, Intravenous; Male; Organic Cation Transport Proteins; Pentanoic Acids; Rats; Rats, Sprague-Dawley; Solute Carrier Family 22 Member 5; Tissue Distribution; Up-Regulation | 2001 |
Possible mechanism for species difference on the toxicity of pivalic acid between dogs and rats.
Topics: Acyl Coenzyme A; Animals; Anti-Bacterial Agents; Carnitine; Dogs; In Vitro Techniques; Kidney; Male; Mitochondria; Muscle, Skeletal; Pentanoic Acids; Rabbits; Rats; Rats, Sprague-Dawley; Species Specificity | 2006 |
Involvement of recognition and interaction of carnitine transporter in the decrease of L-carnitine concentration induced by pivalic acid and valproic acid.
Topics: Acetylcarnitine; Algorithms; Amino Acid Transport Systems, Basic; Animals; Biological Transport, Active; Carnitine; Carrier Proteins; Enzyme Inhibitors; LLC-PK1 Cells; Pentanoic Acids; Swine; Valproic Acid | 2006 |
Role of Na+/L-carnitine transporter (OCTN2) in renal handling of pivaloylcarnitine and valproylcarnitine formed during pivalic acid-containing prodrugs and valproic acid treatment.
Topics: Animals; Carnitine; CHO Cells; Cricetinae; Cricetulus; Humans; Kidney; Male; Organic Cation Transport Proteins; Pentanoic Acids; Prodrugs; Rats; Rats, Sprague-Dawley; Sodium; Solute Carrier Family 22 Member 5; Valproic Acid | 2008 |
Interaction between pivaloylcarnitine and L-carnitine transport into L6 cells overexpressing hOCTN2.
Topics: Animals; Biological Transport; Carnitine; Cell Line; Humans; Kinetics; Organic Cation Transport Proteins; Pentanoic Acids; Rats; Solute Carrier Family 22 Member 5 | 2009 |
Surprising causes of C5-carnitine false positive results in newborn screening.
Topics: Amino Acid Metabolism, Inborn Errors; Belgium; Carnitine; False Positive Reactions; Humans; Infant, Newborn; Isovaleryl-CoA Dehydrogenase; Mass Spectrometry; Neonatal Screening; Ointments; Pentanoic Acids; Prodrugs; Risk Factors | 2014 |
[C5-carnitine false positive results in newborn screening: what is the cause?].
Topics: Amino Acid Metabolism, Inborn Errors; Biotransformation; Breast Feeding; Carnitine; Coenzyme A Ligases; Cosmetics; False Positive Reactions; Female; Humans; Infant, Newborn; Isovaleryl-CoA Dehydrogenase; Maternal-Fetal Exchange; Neonatal Screening; Ointments; Pentanoic Acids; Pregnancy; Tandem Mass Spectrometry | 2015 |
Hypocarnitinemia Observed in an Infant Treated with Short-Term Administration of Antibiotic Containing Pivalic Acid.
Topics: Anti-Bacterial Agents; Carbon; Carnitine; Humans; Hypoglycemia; Infant; Male; Metabolic Diseases; Oxygen; Pentanoic Acids; Tandem Mass Spectrometry | 2018 |