pituitrin and 6-(5-methylimidazol-1-yl)methyl-2-naphthoic-acid-hydrochloride

pituitrin has been researched along with 6-(5-methylimidazol-1-yl)methyl-2-naphthoic-acid-hydrochloride* in 1 studies

Other Studies

1 other study(ies) available for pituitrin and 6-(5-methylimidazol-1-yl)methyl-2-naphthoic-acid-hydrochloride

Article	Year
Importance of secondary TXA2 release in mediating of endothelin-1 induced bronchoconstriction and vasopressin in the guinea-pig. Prostaglandins, leukotrienes, and essential fatty acids, 1993, Volume: 48, Issue:3 The i.v. bolus application of 1 nmol/kg endothelin-1 (ET-1) in anaesthetized and ventilated guinea-pigs caused an increase in mean arterial blood pressure (BP) and a bronchoconstriction. Both have been reduced or abolished by COX inhibition (ASA) or substances specifically reducing the thromboxane A2 (TXA2) generation (HOE 944) or receptor binding (BM 13177). The significant increase in TXB2 concentrations in plasma and bronchoalveolar lavage (BAL) after ET-1 challenge (15-fold and 4-fold, respectively) have been reduced or abolished by ASA as well as HOE 944 and not altered by BM 13177. Topics: Animals; Aspirin; Blood Pressure; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Endothelins; Guinea Pigs; Imidazoles; Male; Naphthalenes; Prostaglandin-Endoperoxide Synthases; Receptors, Thromboxane; Sulfonamides; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Vasopressins	1993

Article

Year

Importance of secondary TXA2 release in mediating of endothelin-1 induced bronchoconstriction and vasopressin in the guinea-pig.

Prostaglandins, leukotrienes, and essential fatty acids, 1993, Volume: 48, Issue:3

The i.v. bolus application of 1 nmol/kg endothelin-1 (ET-1) in anaesthetized and ventilated guinea-pigs caused an increase in mean arterial blood pressure (BP) and a bronchoconstriction. Both have been reduced or abolished by COX inhibition (ASA) or substances specifically reducing the thromboxane A2 (TXA2) generation (HOE 944) or receptor binding (BM 13177). The significant increase in TXB2 concentrations in plasma and bronchoalveolar lavage (BAL) after ET-1 challenge (15-fold and 4-fold, respectively) have been reduced or abolished by ASA as well as HOE 944 and not altered by BM 13177.

Topics: Animals; Aspirin; Blood Pressure; Bronchoalveolar Lavage Fluid; Bronchoconstriction; Endothelins; Guinea Pigs; Imidazoles; Male; Naphthalenes; Prostaglandin-Endoperoxide Synthases; Receptors, Thromboxane; Sulfonamides; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Vasopressins

1993