piroximone has been researched along with enoximone in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (59.09) | 18.7374 |
| 1990's | 9 (40.91) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bobowski, G; Bristol, JA; Burke, SE; Evans, DB; Newton, RS; Sircar, I; Steffen, RP; Weishaar, RE | 1 |
| Bristol, JA; Humblet, CC; McPhail, AT; Moos, WH; Rithner, C; Sircar, I; Weishaar, RE | 1 |
| Bristol, JA; Cain, MH; Weishaar, RE | 1 |
| Erhardt, PW | 1 |
| Boldt, J; Dapper, E; Hempelmann, G; Herold, C; Knothe, C; Zickmann, B | 1 |
| Hausen, B; Haverich, A; Heublein, B; Vogelpohl, J; von der Leyen, H | 1 |
| Thormann, J | 1 |
| Lehot, JJ | 1 |
| Housmyer, CL; Lewis, RL | 1 |
| Blinks, JR; Endoh, M; Taira, N; Yanagisawa, T | 1 |
| Braunwald, E; Colucci, WS; Wright, RF | 1 |
| Hess, ML; Wood, MA | 1 |
| Janicki, JS; Maskin, CS; Weber, KT | 1 |
| Dhainaut, JF | 1 |
| Chiotti, D; Presbitero, P | 1 |
| Goto, T; Nunoki, K; Satoh, K; Taira, N | 1 |
| Taira, N; Wada, Y | 1 |
| Chatterjee, K; Daly, PA; Kereiakes, D; Modin, G; Simonton, CA | 1 |
| Caldicott, LD; Das, P; Patel, A; Sherry, KM; Skoyles, JR | 1 |
| Buerke, M; Cyrus, T; Darius, H | 1 |
| Heintz, B; Kirsten, D; Kirsten, R; Nelson, K | 1 |
| Boldt, J; Hempelmann, G; Knothe, C; Schindler, E; Stertmann, WA; Zickmann, B | 1 |
7 review(s) available for piroximone and enoximone
| Article | Year |
|---|---|
A new generation of phosphodiesterase inhibitors: multiple molecular forms of phosphodiesterase and the potential for drug selectivity.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Blood Platelets; Calmodulin; Cardiotonic Agents; Guinea Pigs; Humans; Hypersensitivity; In Vitro Techniques; Lung Diseases; Myocardium; Platelet Aggregation; Substrate Specificity | 1985 |
In search of the digitalis replacement.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Cardiotonic Agents; Cyclic AMP; Digitalis Glycosides; Heart Failure; Humans; Myocardial Contraction; Receptors, Adrenergic, beta; Structure-Activity Relationship | 1987 |
New positive inotropic agents in the treatment of congestive heart failure. Mechanisms of action and recent clinical developments. 2.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Administration, Oral; Aminopyridines; Amrinone; Cardiotonic Agents; Coenzymes; Enoximone; Heart; Heart Failure; Hemodynamics; Humans; Imidazoles; Injections, Intravenous; Milrinone; Nifedipine; Oxyfedrine; Phosphodiesterase Inhibitors; Pyridazines; Pyridones; Quinazolines; Ubiquinone | 1986 |
Long-term oral therapy of congestive heart failure with phosphodiesterase inhibitors.
Topics: Administration, Oral; Amrinone; Enoximone; Heart Failure; Humans; Imidazoles; Milrinone; Phosphodiesterase Inhibitors; Pyridones | 1989 |
Effects of new inotropic agents on exercise performance.
Topics: Adrenergic beta-Agonists; Aminopyridines; Amrinone; Cardiac Output; Cardiotonic Agents; Chronic Disease; Enoximone; Heart Failure; Humans; Imidazoles; Milrinone; Muscles; Oxygen; Oxygen Consumption; Physical Exertion; Pulmonary Wedge Pressure; Pyridones; Time Factors | 1986 |
[New inotropic drugs].
Topics: Adrenergic beta-Agonists; Amrinone; Cardiotonic Agents; Deoxyepinephrine; Enoximone; Ethanolamines; Heart; Humans; Imidazoles; Milrinone; Myocardial Contraction; Propanolamines; Pyridazines; Pyridones; Vasodilator Agents; Xamoterol | 1988 |
Clinical pharmacokinetics of vasodilators. Part II.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Alprostadil; Amrinone; Carbazoles; Carvedilol; Enoximone; Female; Humans; Iloprost; Imidazoles; Indoramin; Isosorbide Dinitrate; Labetalol; Milrinone; Molsidomine; Nitroglycerin; Nitroprusside; Oxyfedrine; Pentaerythritol Tetranitrate; Phosphodiesterase Inhibitors; Piperazines; Prazosin; Pregnancy; Propanolamines; Pyridones; Theophylline; Trapidil; Vasodilator Agents | 1998 |
4 trial(s) available for piroximone and enoximone
| Article | Year |
|---|---|
Phosphodiesterase-inhibitors enoximone and piroximone in cardiac surgery: influence on platelet count and function.
Topics: Adenosine Triphosphate; Aged; Blood Transfusion; Cardiotonic Agents; Coronary Artery Bypass; Enoximone; Female; Germany; Hemoglobins; Hemorrhage; Hospitals, University; Humans; Imidazoles; Infusions, Intravenous; Injections, Intravenous; Male; Middle Aged; Platelet Aggregation; Platelet Count; Platelet Function Tests; Postoperative Complications; Thrombelastography | 1992 |
Comparison of enoximone and piroximone in patients after mitral valve operation: a prospective and controlled clinical study.
Topics: Aged; Blood Pressure; Cardiotonic Agents; Dopamine; Drug Therapy, Combination; Electrocardiography; Enoximone; Epinephrine; Female; Heart Rate; Humans; Imidazoles; Male; Middle Aged; Mitral Valve; Nitroglycerin; Phosphodiesterase Inhibitors; Postoperative Care; Prospective Studies; Ventricular Function | 1992 |
Comparison of the haemodynamic effects of enoximone and piroximone in patients after cardiac surgery.
Topics: Aged; Blood Pressure; Cardiac Output; Cardiac Surgical Procedures; Cardiotonic Agents; Enoximone; Female; Hemodynamics; Humans; Imidazoles; Male; Middle Aged; Postoperative Care; Vascular Resistance | 1993 |
Circulatory effects of the PDE-inhibitors piroximone and enoximone.
Topics: Aged; Blood Flow Velocity; Blood Pressure; Cardiopulmonary Bypass; Enoximone; Humans; Imidazoles; Laser-Doppler Flowmetry; Male; Microcirculation; Oxygen Consumption; Phosphodiesterase Inhibitors; Vascular Resistance | 1993 |
11 other study(ies) available for piroximone and enoximone
| Article | Year |
|---|---|
Cardiotonic agents. 9. Synthesis and biological evaluation of a series of (E)-4,5-dihydro-6-[2-[4-(1H-imidazol-1-yl)phenyl]ethenyl]-3 (2H)-pyridazinones: a novel class of compounds with positive inotropic, antithrombotic, and vasodilatory activities for t
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cardiotonic Agents; Dogs; Female; Fibrinolytic Agents; Heart Failure; Humans; Imidazoles; Male; Myocardial Contraction; Platelet Aggregation; Pyridazines; Structure-Activity Relationship; Vasodilator Agents | 1989 |
Cardiotonic agents. 8. Selective inhibitors of adenosine 3',5'-cyclic phosphate phosphodiesterase III. Elaboration of a five-point model for positive inotropic activity.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Cardiotonic Agents; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Myocardial Contraction; Spectrophotometry, Infrared; X-Ray Diffraction | 1987 |
The influence of clinical intervention on pressure-volume relationships--the conductance (volume) technique.
Topics: Angioplasty, Balloon, Coronary; Anti-Arrhythmia Agents; Blood Pressure; Cardiac Catheterization; Cardiac Pacing, Artificial; Cardiac Volume; Computer Graphics; Coronary Angiography; Coronary Disease; Enoximone; Heart Failure; Humans; Imidazoles; Myocardial Contraction; Myocardial Ischemia; Phosphodiesterase Inhibitors; Stroke Volume; Ventricular Function, Left | 1992 |
[New positive inotropic drugs].
Topics: Adrenergic Agonists; Amrinone; Cardiotonic Agents; Dopamine; Enoximone; Hemodynamics; Humans; Imidazoles; Milrinone; Myocardial Contraction; Phosphodiesterase Inhibitors; Pyridazines; Pyridones; Shock, Cardiogenic | 1991 |
Electroanalytical characteristics of the cardiotonics, enoximone and piroximone.
Topics: Chromatography, High Pressure Liquid; Electrochemistry; Electrodes; Electrolytes; Enoximone; Hydrogen-Ion Concentration; Imidazoles; Polarography; Solutions | 1991 |
Effects of new inotropic agents on cyclic nucleotide metabolism and calcium transients in canine ventricular muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aequorin; Aminopyridines; Amrinone; Animals; Calcium; Carbachol; Cardiotonic Agents; Colforsin; Cyclic AMP; Dogs; Dose-Response Relationship, Drug; Enoximone; Female; Imidazoles; Male; Milrinone; Myocardial Contraction; Myocardium; Nifedipine; Nucleotides, Cyclic; Pyrazines; Pyridones; Quinolines; Time Factors | 1986 |
[Use of new inotropic agents in the treatment of acute cardiac failure].
Topics: Adrenergic Agonists; Amrinone; Calcium Channel Blockers; Cardiotonic Agents; Dobutamine; Dopamine; Enoximone; Heart Failure; Humans; Imidazoles; Milrinone; Myocardial Contraction; Pyridones | 1988 |
Amelioration of heart failure by MDL 17043 and MDL 19205, novel positive inotropic drugs, in dog heart-lung preparations.
Topics: Animals; Blood Pressure; Cardiac Output; Cardiotonic Agents; Dogs; Dose-Response Relationship, Drug; Enoximone; Female; Heart Conduction System; Heart Failure; Heart Rate; Hemodynamics; Imidazoles; Male | 1985 |
Comparative study of MDL 17043 and MDL 19205, new positive inotropic agents, by use of isolated, blood-perfused dog-heart preparations.
Topics: Animals; Atrioventricular Node; Cardiotonic Agents; Coronary Circulation; Culture Techniques; Dogs; Electrocardiography; Enoximone; Female; Heart Rate; Imidazoles; Male; Myocardial Contraction; Papillary Muscles; Sinoatrial Node; Vasodilation | 1986 |
Survival in severe left ventricular failure treated with the new nonglycosidic, nonsympathomimetic oral inotropic agents.
Topics: Administration, Oral; Aged; Anti-Arrhythmia Agents; Cardiotonic Agents; Death, Sudden; Drug Evaluation; Enoximone; Female; Heart Failure; Humans; Imidazoles; Male; Middle Aged; Milrinone; Pyridones; Quinazolines; Retrospective Studies; Time Factors | 1987 |
Phosphodiesterase inhibitors piroximone and enoximone inhibit platelet aggregation in vivo and in vitro.
Topics: Animals; Blood Platelets; Calcium; Cardiotonic Agents; Cyclic AMP; Enoximone; Humans; Imidazoles; Male; Phosphodiesterase Inhibitors; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Wistar | 1997 |