pironetin and crocacin

Natural products play an important role as lead structures for the identification of novel active ingredients in crop protection. As it is the case in the pharmaceutical industry, however, many crop protection companies have substantially decreased their in-house efforts in natural product exploration. Therefore, joint projects with academic research groups become more and more important in the field. This review describes several examples for successful collaborations in the field of fungicidal natural products.

Topics: Antifungal Agents; Biological Products; Bridged Bicyclo Compounds, Heterocyclic; Drug Industry; Intercellular Signaling Peptides and Proteins; Nucleosides; Peptides; Polyenes; Pyrones; Structure-Activity Relationship