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pirmagrel and 6-ketoprostaglandin f1 alpha

pirmagrel has been researched along with 6-ketoprostaglandin f1 alpha in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-199011 (78.57)18.7374
1990's3 (21.43)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Burke, TA; Danchak, M; Douglas, FL; Fomsgaard, JS; Kim, YD; Myers, AK; Peppard, J; Schaffer, AV; Viswanathan, T1
Glovsky, MM; Horvath, SJ; Morganroth, ML; Schoeneich, SO; Till, GO; Ward, PA1
Edhag, O; Gréen, K; Henriksson, P; Rasmanis, G; Vesterqvist, O1
Kadowitz, PJ; Mayeux, PR; McNamara, DB1
FitzGerald, GA; Nowak, J1
Doran, JB; FitzGerald, GA; Reilly, IA; Smith, B1
Butler, KD; Shand, RA; Wallis, RB1
Ahmed, SW; Douglas, F; Foegh, ML; Franco, K; Katz, NM; Kim, YD; Ku, E; Ng, L; Siegelman, R; Wallace, RB1
Anner, H; Hechtman, HB; Kaufman, RP; Kobzik, L; Shepro, D; Valeri, CR1
DeCampli, WM; Goodwin, D; Handen, CE; Kosek, JC; Miller, DC; Mitchell, RS1
Brigmon, L; Lawson, DL; Mehta, J; Mehta, P; Ostrowski, N1
Brash, A; Fitzgerald, G; Oates, JA1
Cash, WD; Chertock, H; Ku, EC; McPherson, SE; Signor, C1
Maguire, ED; Wallis, RB1

Trials

1 trial(s) available for pirmagrel and 6-ketoprostaglandin f1 alpha

ArticleYear
Increased thromboxane biosynthesis in a human preparation of platelet activation: biochemical and functional consequences of selective inhibition of thromboxane synthase.
    Circulation, 1986, Volume: 73, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Aged; Arteriosclerosis; beta-Thromboglobulin; Epoprostenol; Female; Humans; Imidazoles; Male; Middle Aged; Platelet Aggregation; Platelet Factor 4; Pyridines; Thromboxane B2; Thromboxane-A Synthase

1986

Other Studies

13 other study(ies) available for pirmagrel and 6-ketoprostaglandin f1 alpha

ArticleYear
Comparison of thromboxane synthetase inhibitor and methylprednisolone effects on protamine responses in dogs.
    Anesthesia and analgesia, 1992, Volume: 74, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Dogs; Drug Interactions; Hemodynamics; Imidazoles; Methylprednisolone; Protamines; Pyridines; Thromboxane B2; Thromboxane-A Synthase

1992
C3a57-77, a C-terminal peptide, causes thromboxane-dependent pulmonary vascular constriction in isolated perfused rat lungs.
    The American review of respiratory disease, 1990, Volume: 141, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Benzofurans; Blood Pressure; Complement C3a; Cyclooxygenase Inhibitors; Imidazoles; In Vitro Techniques; Indomethacin; Lung; Male; Peptide Fragments; Perfusion; Pyridines; Rats; Thromboxane B2; Thromboxane-A Synthase; Vasoconstriction

1990
Thromboxane synthase inhibition: "endoperoxide shunt phenomenon" does not occur in healthy humans in vivo.
    Prostaglandins, 1990, Volume: 39, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Epoprostenol; Humans; Imidazoles; Male; Pyridines; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes

1990
Evidence for a bidirectional prostaglandin endoperoxide shunt between platelets and the bovine coronary artery.
    Biochimica et biophysica acta, 1989, Mar-28, Volume: 1011, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Cattle; Coronary Vessels; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme System; Epoprostenol; Humans; Imidazoles; Intramolecular Oxidoreductases; Isomerases; Prostaglandin Endoperoxides; Prostaglandin Endoperoxides, Synthetic; Prostaglandin H2; Prostaglandins H; Pyridines; Thromboxane B2; Thromboxane-A Synthase

1989
Redirection of prostaglandin endoperoxide metabolism at the platelet-vascular interface in man.
    The Journal of clinical investigation, 1989, Volume: 83, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Bleeding Time; Blood Platelets; Blood Vessels; Epoprostenol; Gas Chromatography-Mass Spectrometry; Humans; Imidazoles; Prostaglandin Endoperoxides; Pyridines; Reference Values; Thromboxane A2; Thromboxane B2

1989
The effects of modulation of prostanoid metabolism on the thoracic platelet accumulation induced by intravenous administration of collagen in the guinea-pig.
    Thrombosis and haemostasis, 1986, Dec-15, Volume: 56, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Platelets; Chromium Radioisotopes; Collagen; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Guinea Pigs; Imidazoles; Injections, Intravenous; Platelet Aggregation; Platelet Count; Prostaglandins; Pyridines; Thorax; Thromboxane B2; Thromboxanes

1986
Effects of CGS-13080, a thromboxane inhibitor, on pulmonary vascular resistance in patients after mitral valve replacement surgery.
    Circulation, 1988, Volume: 78, Issue:3 Pt 2

    Topics: 6-Ketoprostaglandin F1 alpha; Cardiopulmonary Bypass; Heart Valve Prosthesis; Hemodynamics; Humans; Hypertension, Pulmonary; Imidazoles; Mitral Valve; Postoperative Complications; Pulmonary Circulation; Pyridines; Thromboxane B2; Thromboxane-A Synthase; Vascular Resistance

1988
A high plasma prostaglandin to thromboxane ratio protects against renal ischemia.
    Surgery, gynecology & obstetrics, 1987, Volume: 165, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Benzofurans; Creatinine; Evaluation Studies as Topic; Ibuprofen; Imidazoles; Ischemia; Kidney; Kidney Tubular Necrosis, Acute; Male; Methacrylates; Pyridines; Rats; Thromboxane B2; Thromboxane-A Synthase

1987
Pharmacological, hematological, and physiological effects of a new thromboxane synthetase inhibitor (CGS-13080) during cardiopulmonary bypass in dogs.
    The Annals of thoracic surgery, 1986, Volume: 42, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood; Cardiopulmonary Bypass; Dogs; Double-Blind Method; Drug Evaluation, Preclinical; Female; Hemodynamics; Imidazoles; Male; Platelet Count; Pyridines; Random Allocation; Thromboxane B2; Thromboxane-A Synthase; Time Factors

1986
Influence of selective thromboxane synthetase blocker CGS-13080 on thromboxane and prostacyclin biosynthesis in whole blood: evidence for synthesis of prostacyclin by leukocytes from platelet-derived endoperoxides.
    The Journal of laboratory and clinical medicine, 1985, Volume: 106, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Platelets; Calcimycin; Calcium Chloride; Collagen; Epoprostenol; Imidazoles; Indomethacin; Leukocytes; Oxidoreductases; Platelet Aggregation; Pyridines; Rabbits; Thromboxane A2; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes

1985
Comparison of the effects of selective inhibition of thromboxane synthase with those of inhibition of the cyclooxygenase enzyme in man.
    Transactions of the American Clinical and Climatological Association, 1984, Volume: 95

    Topics: 6-Ketoprostaglandin F1 alpha; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Imidazoles; Male; Oxidoreductases; Pyridines; Thromboxane-A Synthase; Time Factors

1984
Characterization of imidazo[1,5-a]pyridine-5-hexanoic acid (CGS 13080) as a selective thromboxane synthetase inhibitor using in vitro and in vivo biochemical models.
    Biochemical and biophysical research communications, 1983, May-16, Volume: 112, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Platelets; Humans; Imidazoles; In Vitro Techniques; Male; Oxidoreductases; Prostaglandins E; Pyridines; Rats; Rats, Inbred Strains; Thromboxane B2; Thromboxane-A Synthase

1983
In vivo redirection of prostaglandin endoperoxides into 6-keto PGF1 alpha formation by thromboxane synthetase inhibitors in the rat.
    Thrombosis research, 1983, Oct-01, Volume: 32, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Platelets; Collagen; Imidazoles; Indoles; Indomethacin; Male; Oxidoreductases; Pyridines; Radioimmunoassay; Rats; Rats, Inbred Strains; Thrombocytopenia; Thromboxane B2; Thromboxane-A Synthase; Thromboxanes

1983