piritrexim has been researched along with nadp in 3 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cody, V; Nowak, W; Wojtczak, A | 1 |
| Borhani, DW; Héroux, A; Johnson, CA; Klon, AE; Pathak, V; Piper, JR; Ross, LJ | 1 |
| Cody, V; Gangjee, A; Namjoshi, OA; Pace, J | 1 |
3 other study(ies) available for piritrexim and nadp
| Article | Year |
|---|---|
Computer modeling studies of the structural role of NADPH binding to active site mutants of human dihydrofolate reductase in complex with piritrexim.
Topics: Antineoplastic Agents; Binding Sites; Humans; Models, Molecular; Mutation; NADP; Point Mutation; Protein Binding; Pyrimidines; Software; Tetrahydrofolate Dehydrogenase | 2001 |
Atomic structures of human dihydrofolate reductase complexed with NADPH and two lipophilic antifolates at 1.09 a and 1.05 a resolution.
Topics: Amino Acid Sequence; Animals; Catalytic Domain; Crystallography, X-Ray; Folic Acid Antagonists; Humans; Hydrogen Bonding; In Vitro Techniques; Macromolecular Substances; Models, Molecular; Molecular Sequence Data; NADP; Protein Conformation; Pyrimidines; Recombinant Proteins; Sequence Homology, Amino Acid; Tetrahydrofolate Dehydrogenase; Toxoplasma | 2002 |
Structure-activity correlations for three pyrido[2,3-d]pyrimidine antifolates binding to human and Pneumocystis carinii dihydrofolate reductase.
Topics: Amino Acid Motifs; Anti-Bacterial Agents; Catalytic Domain; Crystallization; Crystallography, X-Ray; Folic Acid Antagonists; Halogenation; Humans; Models, Molecular; Molecular Sequence Data; NADP; Pneumocystis carinii; Protein Binding; Pyrimidines; Recombinant Proteins; Species Specificity; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase | 2015 |