pirinixic acid has been researched along with tretinoin in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (33.33) | 18.2507 |
| 2000's | 9 (37.50) | 29.6817 |
| 2010's | 7 (29.17) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Gellrich, L; Heering, J; Kaiser, A; Kalinowsky, L; Kilu, W; Merk, D; Ohrndorf, J; Pollinger, J; Proschak, E; Schierle, S; Schmidt, J | 1 |
| Aldridge, TC; Green, S; Issemann, I; Prince, RA; Tugwood, JD | 1 |
| Chawla, A; Lazar, MA | 1 |
| Brierley, CH; Burchell, B; Clarke, D; Hsu, MH; Johnson, EF; Senafi, SB | 1 |
| Albrektsen, T; Gustafsson, JA; Johansson, L; Leers, J; Treuter, E | 1 |
| Kockx, M; Kooistra, T; Princen, HM | 1 |
| Gebicke-Haerter, PJ; Kakimura, J; Kitamura, Y; Matsuoka, Y; Nomura, Y; Taniguchi, T | 1 |
| Barberá, MJ; Carmona, MC; Giralt, M; Iglesias, R; Mampel, T; Valmaseda, A; Villarroya, F; Viñas, O | 1 |
| Clapham, JC; Smith, SA; Teruel, T | 1 |
| Bláha, L; Hofmanová, J; Kozubík, A; Minksová, K; Soucek, K; Stika, J; Vondrácek, J | 1 |
| Bouzakri, K; Chevillotte, E; Rieusset, J; Roques, M; Vidal, H | 1 |
| May, FJ; Monteith, GR; Roberts-Thomson, SJ; Smith, SA | 1 |
| Chang, C; Chang, E; Inui, S; Lee, YF; Shyr, CR | 1 |
| Berbe, V; Bouzakri, K; Debard, C; Laville, M; Rieusset, J; Roques, M; Vidal, H | 1 |
| Akerblad, P; Améen, C; Asp, L; Edvardsson, U; Lindén, D; Ljungberg, A; Olofsson, SO; Oscarsson, J; Tuneld, A | 1 |
| Lee, LE; Liu, G; Metcalfe, CD; Moon, TW; Trudeau, VL | 1 |
| Caguyong, MJ; Cornwell, PD; Dai, X; De Souza, AT; Ulrich, RG | 1 |
| Lerch, R; Montessuit, C; Papageorgiou, I | 1 |
| Felder, T; Hahne, P; Krempler, F; Miller, K; Oberkofler, H; Patsch, W; Pfeifenberger, A; Soyal, S | 1 |
| Avenia, N; Bonafé, M; Ceccarelli, C; De Carolis, S; Guarnieri, T; Orlandi, M; Papi, A; Sanguinetti, A; Santini, D; Sidoni, A; Storci, G; Taffurelli, M | 1 |
| Choi, KY; Kim, B; Kim, H; Kim, JE; Lee, JD; Lee, SH | 1 |
| Cui, Y; Ding, J; Li, HR; Sun, GJ; Wang, J; Wang, SJ; Zhang, JX | 1 |
1 review(s) available for pirinixic acid and tretinoin
| Article | Year |
|---|---|
Delineating peroxisome proliferator action to improve human risk assessment.
Topics: Acyl-CoA Oxidase; Animals; Base Sequence; Clofibrate; Cloning, Molecular; Diethylhexyl Phthalate; DNA; Fatty Acids; Humans; Liver; Liver Neoplasms, Experimental; Mice; Microbodies; Molecular Sequence Data; Oxidoreductases; Promoter Regions, Genetic; Pyrimidines; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Risk Assessment; Transcription Factors; Tretinoin | 1994 |
23 other study(ies) available for pirinixic acid and tretinoin
| Article | Year |
|---|---|
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Tuning Nuclear Receptor Selectivity of Wy14,643 towards Selective Retinoid X Receptor Modulation.
Topics: Animals; HEK293 Cells; Hep G2 Cells; Humans; Male; Mice, Inbred C57BL; Microsomes, Liver; Molecular Structure; Peroxisome Proliferator-Activated Receptors; Pyrimidines; Rats; Retinoid X Receptors; Structure-Activity Relationship | 2019 |
Peroxisome proliferator and retinoid signaling pathways co-regulate preadipocyte phenotype and survival.
Topics: 3T3 Cells; 5,8,11,14-Eicosatetraynoic Acid; Adipose Tissue; Animals; Apoptosis; Cell Survival; Clofibrate; Culture Media; Mice; Microbodies; Phenotype; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Signal Transduction; Stem Cells; Transcription Factors; Tretinoin | 1994 |
Regulation of the human bilirubin UDP-glucuronosyltransferase gene.
Topics: Base Sequence; Binding Sites; Cells, Cultured; Consensus Sequence; Gene Expression Regulation; Genes, Reporter; Glucuronosyltransferase; Humans; Microsomes, Liver; Molecular Sequence Data; Phenobarbital; Pyrimidines; TATA Box; Transcription Factors; Tretinoin; Xenobiotics | 1996 |
A regulatory role for RIP140 in nuclear receptor activation.
Topics: Adaptor Proteins, Signal Transducing; Alitretinoin; Amino Acid Sequence; Animals; Binding, Competitive; Cell Nucleus; Cloning, Molecular; Dimerization; DNA-Binding Proteins; Fatty Acids; Gene Expression Regulation; Gene Library; Histone Acetyltransferases; Humans; Macromolecular Substances; Molecular Sequence Data; Nuclear Proteins; Nuclear Receptor Co-Repressor 1; Nuclear Receptor Coactivator 1; Nuclear Receptor Coactivators; Nuclear Receptor Interacting Protein 1; Oncogene Proteins; Pyrimidines; Rabbits; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Receptors, Thyroid Hormone; Recombinant Fusion Proteins; Repressor Proteins; Retinoid X Receptors; Rosiglitazone; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Thiazoles; Thiazolidinediones; Trans-Activators; Transcription Factors; Transcription, Genetic; Transfection; Tretinoin; Zinc Fingers | 1998 |
Fibrate-modulated expression of fibrinogen, plasminogen activator inhibitor-1 and apolipoprotein A-I in cultured cynomolgus monkey hepatocytes -- role of the peroxisome proliferator-activated receptor-alpha.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Alitretinoin; Animals; Apolipoprotein A-I; Cells, Cultured; Clofibrate; Clofibric Acid; Dimerization; Female; Fenofibrate; Fibric Acids; Fibrinogen; Gemfibrozil; Gene Expression Regulation; Genes, Reporter; Hypolipidemic Agents; Liver; Macaca fascicularis; Male; Peroxisome Proliferators; Plasminogen Activator Inhibitor 1; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Transcription Factors; Transcriptional Activation; Tretinoin | 1998 |
Activators of peroxisome proliferator-activated receptor-gamma (PPARgamma) inhibit inducible nitric oxide synthase expression but increase heme oxygenase-1 expression in rat glial cells.
Topics: Alitretinoin; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Cells, Cultured; Dinoprostone; Enzyme Induction; Gene Expression Regulation, Enzymologic; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Interferon-gamma; Lipopolysaccharides; Neuroglia; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Prostaglandin D2; Pyrimidines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Tretinoin | 1999 |
Opposite regulation of PPAR-alpha and -gamma gene expression by both their ligands and retinoic acid in brown adipocytes.
Topics: Adipocytes; Adipose Tissue, Brown; Animals; Cell Differentiation; Cells, Cultured; DNA-Binding Proteins; Gene Expression Regulation; Ligands; Male; Mice; Prostaglandin D2; Protein Isoforms; Pyrimidines; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Transcription Factors; Tretinoin | 1999 |
PPARalpha activation by Wy 14643 induces transactivation of the rat UCP-1 promoter without increasing UCP-1 mRNA levels and attenuates PPARgamma-mediated increases in UCP-1 mRNA levels induced by rosiglitazone in fetal rat brown adipocytes.
Topics: Adipose Tissue, Brown; Alitretinoin; Animals; Carrier Proteins; Cells, Cultured; Gene Expression Regulation; Ion Channels; Membrane Proteins; Mitochondrial Proteins; Peroxisome Proliferators; Promoter Regions, Genetic; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection; Tretinoin; Uncoupling Protein 1 | 1999 |
Inhibitors of arachidonic acid metabolism potentiate tumour necrosis factor-alpha-induced apoptosis in HL-60 cells.
Topics: Apoptosis; Arachidonic Acid; Caspase 3; Caspases; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytochrome c Group; Cytosol; Dose-Response Relationship, Drug; Drug Synergism; HL-60 Cells; Humans; Indomethacin; Isoenzymes; Masoprocol; Membrane Proteins; Peroxisome Proliferators; Phospholipases A; Phospholipases A2; Prostaglandin-Endoperoxide Synthases; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Tretinoin; Tumor Necrosis Factor-alpha | 2001 |
Regulation of p85alpha phosphatidylinositol-3-kinase expression by peroxisome proliferator-activated receptors (PPARs) in human muscle cells.
Topics: Alitretinoin; Blotting, Western; Cells, Cultured; Female; Gene Expression Regulation, Enzymologic; Humans; Male; Middle Aged; Muscle, Skeletal; Phosphatidylinositol 3-Kinases; Pyrimidines; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Transcription Factors; Tretinoin; Up-Regulation | 2001 |
Activation of the peroxisome proliferator-activated receptor-alpha enhances cell death in cultured cerebellar granule cells.
Topics: Alitretinoin; Animals; Apoptosis; Cells, Cultured; Cerebellar Cortex; L-Lactate Dehydrogenase; Nerve Tissue Proteins; Neurons; Potassium Chloride; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factors; Tretinoin; Up-Regulation | 2001 |
Differential and bi-directional regulation between TR2/TR4 orphan nuclear receptors and a specific ligand mediated-peroxisome proliferator-activated receptor alpha in human HaCaT keratinocytes.
Topics: Binding, Competitive; Cell Line; Down-Regulation; Humans; Keratinocytes; Ligands; Nuclear Receptor Subfamily 2, Group C, Member 1; Peroxisome Proliferators; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Receptors, Thyroid Hormone; Response Elements; Transcription Factors; Transcriptional Activation; Tretinoin; Up-Regulation | 2003 |
WY-14643 and 9- cis-retinoic acid induce IRS-2/PI 3-kinase signalling pathway and increase glucose transport in human skeletal muscle cells: differential effect in myotubes from healthy subjects and Type 2 diabetic patients.
Topics: Adult; Diabetes Mellitus, Type 2; Glucose; Humans; Insulin; Insulin Receptor Substrate Proteins; Intracellular Signaling Peptides and Proteins; Muscle Fibers, Skeletal; Muscle, Skeletal; Phosphatidylinositol 3-Kinases; Phosphoproteins; Pyrimidines; Reference Values; Signal Transduction; Tretinoin | 2004 |
Activation of peroxisome proliferator-activated receptor alpha increases the expression and activity of microsomal triglyceride transfer protein in the liver.
Topics: Alitretinoin; Animals; Apolipoproteins B; Carrier Proteins; Cell Line; Cells, Cultured; Dactinomycin; Gene Expression Regulation; Hepatocytes; Liver; Male; Mice; Mice, Inbred C57BL; PPAR alpha; Promoter Regions, Genetic; Pyrimidines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Transcription, Genetic; Tretinoin | 2005 |
A teleost in vitro reporter gene assay to screen for agonists of the peroxisome proliferator-activated receptors.
Topics: Acetyl-CoA C-Acyltransferase; Alitretinoin; Angiogenesis Inhibitors; Animals; Bezafibrate; Cloning, Molecular; DNA; DNA, Complementary; Dose-Response Relationship, Drug; Environmental Monitoring; Gemfibrozil; Genes, Reporter; Humans; Hypolipidemic Agents; In Vitro Techniques; Liver; Luciferases; Oncorhynchus mykiss; Peroxisome Proliferator-Activated Receptors; Peroxisome Proliferators; Plasmids; PPAR alpha; PPAR-beta; Promoter Regions, Genetic; Pyrimidines; Rats; Retinoid X Receptors; Transcription, Genetic; Transfection; Tretinoin; Water Pollutants, Chemical | 2005 |
Agonists of the peroxisome proliferator-activated receptor alpha induce a fiber-type-selective transcriptional response in rat skeletal muscle.
Topics: Animals; Bezafibrate; Fatty Acids; Female; Fenofibrate; Gene Expression Profiling; Glucose; Hypolipidemic Agents; Liver; Muscle Fibers, Slow-Twitch; Muscle, Skeletal; PPAR alpha; Pyrimidines; Rats; Rats, Inbred Strains; Rosiglitazone; Thiazolidinediones; Tretinoin | 2006 |
Nuclear receptor agonists improve insulin responsiveness in cultured cardiomyocytes through enhanced signaling and preserved cytoskeletal architecture.
Topics: Alitretinoin; AMP-Activated Protein Kinase Kinases; Animals; Cells, Cultured; Cytoskeleton; Glucose; Glucose Transporter Type 4; Insulin; Insulin Resistance; Male; Microtubules; Myocytes, Cardiac; Phenoxyacetates; PPAR gamma; Protein Kinases; Pyrimidines; Rats; Rats, Sprague-Dawley; Retinoid X Receptors; Signal Transduction; Thiazolidinediones; Tretinoin | 2008 |
Aberrant hepatic TRIB3 gene expression in insulin-resistant obese humans.
Topics: Carrier Proteins; Cell Cycle Proteins; Gene Expression; Heat-Shock Proteins; Hep G2 Cells; Humans; Insulin Resistance; Liver; Obesity; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; PPAR alpha; Protein Serine-Threonine Kinases; Pyrimidines; Repressor Proteins; RNA-Binding Proteins; RNA, Messenger; Sterol Regulatory Element Binding Protein 1; Transcription Factors; Tretinoin | 2010 |
Nuclear receptors agonists exert opposing effects on the inflammation dependent survival of breast cancer stem cells.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Survival; Female; Humans; Inflammation; Interleukin-6; Neoplastic Stem Cells; NF-kappa B; Phenanthrenes; Pioglitazone; PPAR gamma; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Thiazolidinediones; Tretinoin | 2012 |
Co-treatment with retinyl retinoate and a PPARα agonist reduces retinoid dermatitis.
Topics: Administration, Topical; Animals; Cell Differentiation; Cell Proliferation; Dermatitis; Enzyme Inhibitors; Epidermis; Female; Interleukin-1alpha; Interleukin-8; Keratolytic Agents; Liver X Receptors; Mice; Mice, Hairless; Orphan Nuclear Receptors; Palmitic Acid; PPAR alpha; Pyrimidines; Retinoids; Retinyl Esters; RNA, Messenger; Tretinoin; Tumor Necrosis Factor-alpha; Water Loss, Insensible | 2012 |
WY14643 combined with all-trans retinoic acid acts via p38 MAPK to induce "browning" of white adipocytes in mice.
Topics: 3T3-L1 Cells; Adipocytes, Brown; Adipocytes, White; Animals; Cell Differentiation; Drug Synergism; Gene Expression Regulation; Imidazoles; Ion Channels; Male; Mice; Mitochondrial Proteins; p38 Mitogen-Activated Protein Kinases; Phosphorylation; PPAR alpha; Pyridines; Pyrimidines; RNA, Messenger; Signal Transduction; Tretinoin; Uncoupling Protein 1 | 2015 |