Compounds > pirinixic acid
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pirinixic acid and transforming growth factor beta

pirinixic acid has been researched along with transforming growth factor beta in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (20.00)18.2507
2000's6 (60.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davies, MJ; Lake, BG; Price, RJ; Rumsby, PC1
Marsman, DS; Popp, JA; Swanson-Pfeiffer, CL1
Cunninghame, ME; Lake, BG; Price, RJ; Rumsby, PC1
Bruemmer, D; Feng, X; Fleck, E; Goetze, S; Graf, K; Hsueh, WA; Kintscher, U; Law, RE; Lyon, C; Moustakas, A; Staels, B; Wakino, S1
Dixon, CL; Hebert, C; Lu, L; Rovin, BH; Wilmer, WA1
Farrell, G; Hall, P; Ip, E; Leclercq, I; Robertson, G1
Chanda, D; Chiang, JY; Choi, HS; Hwang, JH; Jeong, KH; Kim, DK; Kim, YH; Kweon, GR; Lee, CH; Lee, IK; Lee, MR; Noh, JR; Oh, GT; Park, JH; Shong, M1
Higuchi, T; Hiratuka, M; Iwasaki, A; Kuroki, M; Maekawa, S; Shibaguchi, H; Shiraishi, T; Shirakusa, T; Tanaka, T; Yanagisawa, J1
Amann, T; Bauer, S; Buechler, C; Eisinger, K; Hellerbrand, C; Neumeier, M; Schäffler, A; Schölmerich, J; Walter, R; Wanninger, J; Weiss, TS1
Cevey, Á; Gómez, MI; González, CD; Goren, NB; Mirkin, GA; Penas, F; Sales, ME; Vera, M1

Other Studies

10 other study(ies) available for pirinixic acid and transforming growth factor beta

ArticleYear
Effect of some peroxisome proliferators on transforming growth factor-beta 1 gene expression and insulin-like growth factor II/mannose-6-phosphate receptor gene expression in rat liver.
    Carcinogenesis, 1994, Volume: 15, Issue:2

    Topics: Animals; Clofenapate; Clofibric Acid; Corn Oil; Gene Expression; Liver; Male; Microbodies; Nafenopin; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, IGF Type 2; Transforming Growth Factor beta

1994
Lack of comitogenicity by the peroxisome proliferator hepatocarcinogens, Wy-14,643 and clofibric acid.
    Toxicology and applied pharmacology, 1993, Volume: 122, Issue:1

    Topics: Animals; Autoradiography; Cell Division; Cells, Cultured; Clofibric Acid; DNA Replication; Dose-Response Relationship, Drug; Epidermal Growth Factor; Liver; Male; Microbodies; Mitogens; Pyrimidines; Rats; Rats, Inbred F344; Transforming Growth Factor beta

1993
Species differences in hepatic peroxisome proliferation, cell replication and transforming growth factor-beta1 gene expression in the rat, Syrian hamster and guinea pig.
    Mutation research, 2000, Mar-17, Volume: 448, Issue:2

    Topics: Animals; Cell Division; Clofenapate; Clofibric Acid; Cricetinae; DNA; Fibric Acids; Gene Expression; Guinea Pigs; Liver; Male; Mesocricetus; Molecular Structure; Organ Size; Peroxisome Proliferators; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, IGF Type 2; Species Specificity; Transforming Growth Factor beta

2000
PPARalpha inhibits TGF-beta-induced beta5 integrin transcription in vascular smooth muscle cells by interacting with Smad4.
    Circulation research, 2002, Nov-29, Volume: 91, Issue:11

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Cell Movement; Cells, Cultured; DNA-Binding Proteins; Gene Expression; Genes, Reporter; Integrin beta Chains; Integrin beta3; Ligands; Macromolecular Substances; Muscle, Smooth, Vascular; Nuclear Proteins; Platelet-Derived Growth Factor; Promoter Regions, Genetic; Protein Binding; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Signal Transduction; Smad4 Protein; Trans-Activators; Transcription Factors; Transcription, Genetic; Transforming Growth Factor beta

2002
PPAR-alpha ligands inhibit H2O2-mediated activation of transforming growth factor-beta1 in human mesangial cells.
    Antioxidants & redox signaling, 2002, Volume: 4, Issue:6

    Topics: Cells, Cultured; Clofibrate; Dose-Response Relationship, Drug; Genetic Vectors; Glomerular Mesangium; Humans; Hydrogen Peroxide; Immunohistochemistry; Ligands; Luciferases; Mitogen-Activated Protein Kinases; Plasmids; Promoter Regions, Genetic; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Transduction, Genetic; Transforming Growth Factor beta; Transforming Growth Factor beta1

2002
Administration of the potent PPARalpha agonist, Wy-14,643, reverses nutritional fibrosis and steatohepatitis in mice.
    Hepatology (Baltimore, Md.), 2004, Volume: 39, Issue:5

    Topics: Animals; Cell Adhesion Molecules; Connective Tissue Growth Factor; Dietary Fats; Fatty Liver; Gene Expression; Hepatocytes; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Lipid Peroxides; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Peroxisome Proliferators; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1; Triglycerides

2004
Fenofibrate differentially regulates plasminogen activator inhibitor-1 gene expression via adenosine monophosphate-activated protein kinase-dependent induction of orphan nuclear receptor small heterodimer partner.
    Hepatology (Baltimore, Md.), 2009, Volume: 50, Issue:3

    Topics: AMP-Activated Protein Kinases; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cytokines; Fenofibrate; Male; Mice; Mice, Inbred C57BL; Plasminogen Activator Inhibitor 1; PPAR alpha; Pyrimidines; Rats; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Transcription Factors; Transforming Growth Factor beta

2009
PPARalpha ligand WY14643 reduced acute rejection after rat lung transplantation with the upregulation of IL-4, IL-10 and TGFbeta mRNA expression.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2009, Volume: 28, Issue:11

    Topics: Animals; Graft Rejection; Interleukin-10; Interleukin-4; Lung Transplantation; PPAR alpha; Pyrimidines; Rats; Rats, Inbred BN; Rats, Inbred F344; RNA, Messenger; Transforming Growth Factor beta; Up-Regulation

2009
Adiponectin reduces connective tissue growth factor in human hepatocytes which is already induced in non-fibrotic non-alcoholic steatohepatitis.
    Experimental and molecular pathology, 2011, Volume: 91, Issue:3

    Topics: Adiponectin; Anticholesteremic Agents; Connective Tissue Growth Factor; Down-Regulation; Fatty Liver; Female; Fenofibrate; Hepatocytes; Humans; Male; Non-alcoholic Fatty Liver Disease; Phosphorylation; PPAR alpha; Primary Cell Culture; Pyrimidines; Signal Transduction; Smad2 Protein; Smad3 Protein; Transforming Growth Factor beta

2011
Treatment in vitro with PPARα and PPARγ ligands drives M1-to-M2 polarization of macrophages from T. cruzi-infected mice.
    Biochimica et biophysica acta, 2015, Volume: 1852, Issue:5

    Topics: Animals; Arginase; beta-N-Acetylhexosaminidases; Blotting, Western; Cells, Cultured; Chagas Disease; Cytokines; Host-Pathogen Interactions; Inflammation Mediators; Lectins; Ligands; Macrophage Activation; Macrophages; Male; Mice, Inbred BALB C; Microscopy, Fluorescence; Nitric Oxide Synthase Type II; Phagocytosis; PPAR alpha; PPAR gamma; Prostaglandin D2; Pyrimidines; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Transforming Growth Factor beta; Trypanosoma cruzi

2015