pirinixic acid has been researched along with thiazoles in 62 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 15 (24.19) | 18.2507 |
| 2000's | 41 (66.13) | 29.6817 |
| 2010's | 6 (9.68) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kliewer, SA; Lehmann, JM; Lenhard, JM; Morris, DC; Patel, I; Willson, TM | 1 |
| Kallen, CB; Lazar, MA | 1 |
| Ciletti, N; Deplewski, D; Kentsis, A; Rosenfield, RL | 1 |
| Albrektsen, T; Gustafsson, JA; Johansson, L; Leers, J; Treuter, E | 1 |
| Chinetti, G; Delerive, P; Fadel, A; Fruchart, JC; Habib, A; Koenig, W; Lebret, M; Maclouf, J; Merval, R; Najib, J; Staels, B; Tedgui, A; Torra, IP | 1 |
| Antonucci, M; Chapman, J; Chinetti, G; Delerive, P; Fruchart, JC; Griglio, S; Majd, Z; Najib, J; Staels, B; Torra, IP | 1 |
| Gebicke-Haerter, PJ; Kakimura, J; Kitamura, Y; Matsuoka, Y; Nomura, Y; Taniguchi, T | 1 |
| Brun, S; Carmona, MC; Giralt, M; Iglesias, R; Mampel, T; Villarroya, F; Viñas, O | 1 |
| Eriksson, P; Hamsten, A; Nilsson, L; Takemura, T | 1 |
| Fujita, J; Hosokawa, H; Imachi, H; Ishida, T; Momoi, A; Murao, K; Nakamura, H; Okada, H; Sato, M; Sayo, Y; Takahara, J | 1 |
| Alexandersson, M; Bamberg, K; Bergström, M; Dahllöf, B; Edvardsson, U; Ljung, B | 1 |
| Ide, T; Kadowaki, T; Mochizuki, T; Murakami, K; Suzuki, M | 1 |
| Hosokawa, H; Imachi, H; Ishida, T; Momoi, A; Murao, K; Sato, M; Sayo, Y; Takahara, J | 1 |
| Baugé, E; Chinetti, G; Clavey, V; Copin, C; Dallongeville, J; Fruchart, J; Fruchart, JC; Mariotte, MC; Staels, B | 1 |
| Clapham, JC; Smith, SA; Teruel, T | 1 |
| Chen, T; DaSilva, L; Farrar, WL; Hodge, DR; Resau, JH; Wang, LH; Yang, XY | 1 |
| Clapham, JC; Peterson, J; Smith, SA; Teruel, T | 1 |
| Carmona, MC; Giralt, M; Iglesias, R; Mampel, T; Pedraza, N; Solanes, G; Vazquez, M; Villarroya, F; Viñas, O | 1 |
| Chandraratna, RA; Fleck, E; Goetze, S; Graf, K; Hsueh, WA; Kim, S; Kintscher, U; Law, RE; Nagpal, S; Wakino, S | 1 |
| DeLuca, JG; Doebber, TW; Gonzalez, FJ; Kelly, LJ; Kemp, RK; Moller, DE; Molon-Noblot, S; Peters, JM; Sahoo, SP; Ventre, J; Wu, MS | 1 |
| Anania, FA; Miyahara, T; Motomura, K; Rippe, R; Schrum, L; Tsukamoto, H; Willson, TM; Xiong, S; Yee, HF | 1 |
| Asakawa, M; Komuro, I; Masuda, Y; Nagai, T; Oka, T; Saito, T; Takano, H; Toyozaki, T | 1 |
| Adzet, T; Alegret, M; Cabrero, A; Laguna, JC; Sánchez, RM; Vázquez, M | 1 |
| Banba, N; Hattori, Y; Hishinuma, A; Kakishita, H; Kasai, K; Matsumura, M; Motohashi, S; Sato, N | 1 |
| Anchiraico, GJ; Belury, MA; Fischer, SM; Gimenez-Conti, I; Liu, KL; Maldve, RE; Muga, SJ; Nickel, KP; Thuillier, P | 1 |
| Brüne, B; Von Knethen A, A | 1 |
| Goodwin, GW; Guthrie, P; Laws, FA; Taegtmeyer, H; Wilson, CR; Ying, J; Young, ME | 1 |
| Giralt, M; Iglesias, R; Pedraza, N; Solanes, G; Vázquez, M; Villarroya, F | 1 |
| Harris, SG; Phipps, RP | 1 |
| Baek, SJ; Eling, TE; Hsi, LC; Ikawa, H; Kameda, H; Kamitani, H; Nixon, JB | 1 |
| Albajar, M; Galetto, R; Polanco, JI; Rodríguez-Rey, JC; Zakin, MM | 1 |
| Bláha, L; Hofmanová, J; Kozubík, A; Minksová, K; Soucek, K; Stika, J; Vondrácek, J | 1 |
| Chapman, H; Clapham, JC; Holder, JC; Lister, CA; Moore, GB; Piercy, V; Smith, SA | 1 |
| Ciletti, N; Deplewski, D; Kim, MJ; Michel, S; Reichert, U; Rosenfield, RL | 1 |
| Archer, DC; Cunard, R; DiCampli, D; Glass, CK; Kahn, DA; Kelly, CJ; Ricote, M | 1 |
| Grüb, M; Hombach, V; Kehrle, B; Koenig, W; Kohlhammer, K; Libby, P; Marx, N; Plutzky, J | 1 |
| Baik, EJ; Kim, EJ; Kwon, KJ; Lee, SH; Moon, CH; Park, JY | 1 |
| Blaschke, F; Bungenstock, A; Eilers, F; Fleck, E; Goetze, S; Graf, K; Gräfe, M; Kintscher, U; Law, RE; Stawowy, P | 1 |
| Feinstein, D; Grommes, C; Heneka, MT; Klockgether, T; Koenigsknecht, J; Kraus, JA; Landreth, G; Schlegel, U; Zander, T | 1 |
| Chatterjee, PK; Cuzzocrea, S; Hattori, Y; McDonald, MC; Mota-Filipe, H; Pisano, B; Thiemermann, C; Wayman, NS | 1 |
| Fujimura, Y; Tachibana, H; Yamada, K | 1 |
| Bakke, I; Hammer, TA; Sandvik, AK; Waldum, HL | 1 |
| Cooney, GJ; Ellis, B; Iglesias, MA; Jensen, PB; Kraegen, EW; Larsen, PJ; Sørensen, RV; Wassermann, K; Watson, DG; Wood, L; Ye, JM | 1 |
| Belvisi, MG; Bishop-Bailey, D; Mitchell, JA; Patel, HJ; Yacoub, MH | 1 |
| Kehrer, JP; Tong, Z; Wu, X | 1 |
| Brüne, B; Tautenhahn, A; von Knethen, A | 1 |
| Gardner, DG; Liang, F; Wang, F; Zhang, S | 1 |
| Chen, YE; Cheng, L; Ding, G; Qin, Q; Woods, D; Xiao, Y; Yang, Q | 1 |
| May, FJ; Monteith, GR; Roberts-Thomson, SJ; Robinson, JA; Smith, SA; Venkata, NG | 1 |
| Fu, J; Gaetani, S; Lin, E; Oveisi, F; Piomelli, D | 1 |
| Johnson, TE; Shi, S; Umbenhauer, DR; Zhang, X | 1 |
| De Windt, LJ; Smeets, PJ; Teunissen, BE; Van Bilsen, M; Van der Vusse, GJ; Willemsen, PH | 1 |
| Bronfman, M; Leisewitz, AV; Loyola, G; Martinez, GR; Urrutia, CR | 1 |
| Bordelon, NR; Brodie, TA; Cummings, CA; Faiola, B; Falls, JG; Miller, RT; Peterson, RA; Romach, EH | 1 |
| Gosker, HR; Langen, RC; Remels, AH; Russell, AP; Schols, AM; Schrauwen, P; Spaapen, F; Voncken, JW | 1 |
| Eder, K; Gutgesell, A; Koch, A; König, B; Ringseis, R; Spielmann, J; Stangl, GI; Wen, G | 1 |
| Cigorraga, SB; Galardo, MN; Meroni, SB; Pellizzari, EH; Regueira, M; Riera, MF | 1 |
| Barz, D; Dehm, F; Hanke, T; Kaiser, A; Kunze, J; Lämmerhofer, M; Liening, S; Maczewsky, J; Pillong, M; Popella, SD; Sautebin, L; Schneider, G; Schubert-Zsilavecz, M; Weinigel, C; Werz, O; Wurglics, M | 1 |
| Gomez, RC; Hanke, T; Lamers, C; Schneider, G; Schubert-Zsilavecz, M; Werz, O | 1 |
| Bérubé-Simard, FA; Bousette, N; Haffar, T | 1 |
| Burk, O; Damm, G; Kandel, BA; Schwab, M; Seehofer, D; Thomas, M; Winter, S; Zanger, UM | 1 |
| Agarwal, AK; Garg, A; Sankella, S | 1 |
62 other study(ies) available for pirinixic acid and thiazoles
| Article | Year |
|---|---|
A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation.
Topics: Adipocytes; Animals; Binding, Competitive; Cell Differentiation; Cells, Cultured; Fibroblasts; Hypoglycemic Agents; Ligands; Mice; Microbodies; Prostaglandin D2; Prostaglandins; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Rosiglitazone; Signal Transduction; Thiazoles; Thiazolidinediones; Transcription Factors; Transcriptional Activation | 1995 |
Antidiabetic thiazolidinediones inhibit leptin (ob) gene expression in 3T3-L1 adipocytes.
Topics: 3T3 Cells; Adipocytes; Animals; Base Sequence; Gene Expression Regulation; Hypoglycemic Agents; Leptin; Mice; Molecular Sequence Data; Obesity; Oligodeoxyribonucleotides; Protein Binding; Proteins; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors | 1996 |
Mechanisms of androgen induction of sebocyte differentiation.
Topics: Androgens; Animals; Cell Differentiation; Cells, Cultured; Dihydrotestosterone; Linoleic Acid; Lipids; Pyrimidines; Rats; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Sebaceous Glands; Thiazoles; Thiazolidinediones; Transcription Factors | 1998 |
A regulatory role for RIP140 in nuclear receptor activation.
Topics: Adaptor Proteins, Signal Transducing; Alitretinoin; Amino Acid Sequence; Animals; Binding, Competitive; Cell Nucleus; Cloning, Molecular; Dimerization; DNA-Binding Proteins; Fatty Acids; Gene Expression Regulation; Gene Library; Histone Acetyltransferases; Humans; Macromolecular Substances; Molecular Sequence Data; Nuclear Proteins; Nuclear Receptor Co-Repressor 1; Nuclear Receptor Coactivator 1; Nuclear Receptor Coactivators; Nuclear Receptor Interacting Protein 1; Oncogene Proteins; Pyrimidines; Rabbits; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Receptors, Thyroid Hormone; Recombinant Fusion Proteins; Repressor Proteins; Retinoid X Receptors; Rosiglitazone; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Thiazoles; Thiazolidinediones; Trans-Activators; Transcription Factors; Transcription, Genetic; Transfection; Tretinoin; Zinc Fingers | 1998 |
Activation of human aortic smooth-muscle cells is inhibited by PPARalpha but not by PPARgamma activators.
Topics: Acute-Phase Proteins; Animals; Anti-Inflammatory Agents; Aorta; Coronary Disease; COS Cells; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Fenofibrate; Gemfibrozil; Gene Expression Regulation, Enzymologic; Humans; Hyperlipidemias; Hypolipidemic Agents; Inflammation; Interleukin-1; Interleukin-6; Isoenzymes; Membrane Proteins; Muscle, Smooth, Vascular; NF-kappa B; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Transcription, Genetic | 1998 |
Activation of proliferator-activated receptors alpha and gamma induces apoptosis of human monocyte-derived macrophages.
Topics: Apoptosis; Arteriosclerosis; Caspase 3; Caspases; Cell Differentiation; Humans; Immunohistochemistry; Inflammation; Interferon-gamma; Ligands; Macrophages; NF-kappa B; Pyrimidines; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Signal Transduction; Thiazoles; Thiazolidinediones; Transcription Factors; Transcription, Genetic; Transfection; Tumor Necrosis Factor-alpha | 1998 |
Activators of peroxisome proliferator-activated receptor-gamma (PPARgamma) inhibit inducible nitric oxide synthase expression but increase heme oxygenase-1 expression in rat glial cells.
Topics: Alitretinoin; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Cells, Cultured; Dinoprostone; Enzyme Induction; Gene Expression Regulation, Enzymologic; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Interferon-gamma; Lipopolysaccharides; Neuroglia; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Prostaglandin D2; Pyrimidines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Tretinoin | 1999 |
Activators of peroxisome proliferator-activated receptor-alpha induce the expression of the uncoupling protein-3 gene in skeletal muscle: a potential mechanism for the lipid intake-dependent activation of uncoupling protein-3 gene expression at birth.
Topics: Animals; Bezafibrate; Carrier Proteins; Clofibrate; DNA-Binding Proteins; Eating; Fatty Acids, Nonesterified; Female; Gene Expression Regulation, Developmental; Hypolipidemic Agents; Ion Channels; Leptin; Male; Mice; Mitochondria, Muscle; Mitochondrial Proteins; Muscle Development; Muscle, Skeletal; Peroxisome Proliferators; Proteins; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Recombinant Proteins; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Transcriptional Activation; Uncoupling Protein 3 | 1999 |
Effects of fibrate compounds on expression of plasminogen activator inhibitor-1 by cultured endothelial cells.
Topics: Bezafibrate; Cells, Cultured; Clofibric Acid; Endothelium, Vascular; Fenofibrate; Gemfibrozil; Humans; Hypolipidemic Agents; Plasminogen Activator Inhibitor 1; Pyrimidines; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription, Genetic | 1999 |
Thiazolidinedione inhibits production of RANTES in a cytokine-treated human lung epithelial cell line.
Topics: Cell Line; Chemokine CCL5; Chemotaxis, Leukocyte; Dexamethasone; Eosinophils; Epithelial Cells; Gene Expression Regulation; Humans; Hypersensitivity; In Vitro Techniques; Interleukin-1; Luciferases; Lung; Promoter Regions, Genetic; Pyrimidines; Recombinant Proteins; RNA, Messenger; Thiazoles; Thiazolidinediones; Transcription, Genetic; Transfection; Tumor Necrosis Factor-alpha | 1999 |
Rosiglitazone (BRL49653), a PPARgamma-selective agonist, causes peroxisome proliferator-like liver effects in obese mice.
Topics: Animals; Electrophoresis, Gel, Two-Dimensional; Hypoglycemic Agents; Liver; Male; Mice; Mice, Obese; Obesity; Peroxisome Proliferators; Pyrimidines; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors | 1999 |
Evidence for direct binding of fatty acids and eicosanoids to human peroxisome proliferators-activated receptor alpha.
Topics: Animals; Binding, Competitive; CHO Cells; Cricetinae; Eicosanoids; Fatty Acids; Fatty Acids, Unsaturated; Gene Expression Regulation; Genes, Reporter; Humans; Hydroxyeicosatetraenoic Acids; Inhibitory Concentration 50; Kinetics; Ligands; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidines; Transcription Factors; Transfection | 1999 |
Thiazolidinedione inhibits the production of monocyte chemoattractant protein-1 in cytokine-treated human vascular endothelial cells.
Topics: Chemokine CCL2; Cytokines; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Interleukin-1; Promoter Regions, Genetic; Pyrimidines; Thiazoles; Thiazolidinediones; Time Factors; Tumor Necrosis Factor-alpha | 1999 |
Cell culture conditions determine apolipoprotein CIII secretion and regulation by fibrates in human hepatoma HepG2 cells.
Topics: Animals; Anticholesteremic Agents; Apolipoprotein C-III; Apolipoproteins; Apolipoproteins C; Blood; Carcinoma, Hepatocellular; Cattle; Culture Media; DNA-Binding Proteins; Fenofibrate; Gemfibrozil; Gene Expression Regulation, Neoplastic; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Kinetics; Liver Neoplasms; Pyrimidines; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured | 1999 |
PPARalpha activation by Wy 14643 induces transactivation of the rat UCP-1 promoter without increasing UCP-1 mRNA levels and attenuates PPARgamma-mediated increases in UCP-1 mRNA levels induced by rosiglitazone in fetal rat brown adipocytes.
Topics: Adipose Tissue, Brown; Alitretinoin; Animals; Carrier Proteins; Cells, Cultured; Gene Expression Regulation; Ion Channels; Membrane Proteins; Mitochondrial Proteins; Peroxisome Proliferators; Promoter Regions, Genetic; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection; Tretinoin; Uncoupling Protein 1 | 1999 |
Activation of human T lymphocytes is inhibited by peroxisome proliferator-activated receptor gamma (PPARgamma) agonists. PPARgamma co-association with transcription factor NFAT.
Topics: Base Sequence; Cell Line; Chromans; DNA Probes; DNA-Binding Proteins; Humans; Interleukin-2; Lymphocyte Activation; NFATC Transcription Factors; Nuclear Proteins; Peroxisome Proliferators; Pyrimidines; Receptors, Cytoplasmic and Nuclear; T-Lymphocytes; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone | 2000 |
Synergistic activation of UCP-3 expression in cultured fetal rat brown adipocytes by PPARalpha and PPARgamma ligands.
Topics: Adipose Tissue, Brown; Animals; Base Sequence; Carrier Proteins; Cells, Cultured; DNA Primers; Drug Synergism; Gene Expression Regulation; Ion Channels; Ligands; Membrane Proteins; Mitochondrial Proteins; Peroxisome Proliferators; Pyrimidines; Rats; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Uncoupling Protein 1; Uncoupling Protein 3 | 2000 |
Impaired expression of the uncoupling protein-3 gene in skeletal muscle during lactation: fibrates and troglitazone reverse lactation-induced downregulation of the uncoupling protein-3 gene.
Topics: Animals; Anticholesteremic Agents; Bezafibrate; Carrier Proteins; Chromans; Female; Gene Expression Regulation; Hypoglycemic Agents; Hypolipidemic Agents; Ion Channels; Lactation; Litter Size; Mice; Microbodies; Mitochondria, Muscle; Mitochondrial Proteins; Muscle, Skeletal; Pyrimidines; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Thiazoles; Thiazolidinediones; Transcription Factors; Transcription, Genetic; Troglitazone; Uncoupling Agents; Uncoupling Protein 3; Weaning | 2000 |
Peroxisome proliferator-activated receptor and retinoid X receptor ligands inhibit monocyte chemotactic protein-1-directed migration of monocytes.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Cell Movement; Chemokine CCL2; Chemotaxis; Chromans; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Humans; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinases; Monocytes; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Rosiglitazone; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidinediones; Tissue Inhibitor of Metalloproteinase-1; Transcription Factors; Troglitazone; Tumor Cells, Cultured | 2000 |
Evidence for peroxisome proliferator-activated receptor (PPAR)alpha-independent peroxisome proliferation: effects of PPARgamma/delta-specific agonists in PPARalpha-null mice.
Topics: Animals; Female; Gene Expression Regulation; Liver; Male; Mice; Mice, Inbred ICR; Organ Size; Peroxisome Proliferators; Peroxisomes; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors | 2000 |
Peroxisome proliferator-activated receptors and hepatic stellate cell activation.
Topics: Animals; Cell Size; Cell Survival; Cells, Cultured; Collagen; DNA; Gene Expression Regulation; Liver; Liver Cirrhosis, Biliary; Liver Cirrhosis, Experimental; Male; Promoter Regions, Genetic; Prostaglandin D2; Protein Binding; Protein Isoforms; Pyrimidines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Tumor Necrosis Factor-alpha | 2000 |
Peroxisome proliferator-activated receptor activators inhibit lipopolysaccharide-induced tumor necrosis factor-alpha expression in neonatal rat cardiac myocytes.
Topics: Animals; Cell Nucleus; Cells, Cultured; Chromans; Drug Interactions; Gemfibrozil; Hypoglycemic Agents; Lipopolysaccharides; Myocardium; NF-kappa B; Peroxisome Proliferators; Pyrimidines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Signal Transduction; Thiazoles; Thiazolidinediones; Transcription Factors; Transcription, Genetic; Troglitazone; Tumor Necrosis Factor-alpha | 2000 |
Down-regulation of uncoupling protein-3 and -2 by thiazolidinediones in C2C12 myotubes.
Topics: Acyl-CoA Dehydrogenase; Animals; Atorvastatin; Bezafibrate; Carnitine O-Palmitoyltransferase; Carrier Proteins; Cell Line; Cholesterol; Chromans; Down-Regulation; Fatty Acid Desaturases; Heptanoic Acids; Hypoglycemic Agents; Ion Channels; Ligands; Membrane Transport Proteins; Mice; Mitochondrial Proteins; Muscles; Oleic Acid; Peroxisome Proliferators; Proteins; Pyrimidines; Pyrroles; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Thiazoles; Thiazolidinediones; Transcription Factors; Triazenes; Troglitazone; Uncoupling Protein 2; Uncoupling Protein 3 | 2000 |
15-Deoxy-Delta(12,14)-prostaglandin J(2) facilitates thyroglobulin production by cultured human thyrocytes.
Topics: Anticholesteremic Agents; Arsenites; Bucladesine; Cells, Cultured; Chromans; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fetal Proteins; Gene Expression Regulation, Enzymologic; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Hypoglycemic Agents; Ligands; Membrane Proteins; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Pioglitazone; Prostaglandin D2; Pyrimidines; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Sodium Compounds; Thiazoles; Thiazolidinediones; Thyroglobulin; Thyroid Gland; Thyrotropin; Transcription Factors; Troglitazone | 2000 |
Activators of peroxisome proliferator-activated receptor-alpha partially inhibit mouse skin tumor promotion.
Topics: Animals; Anticarcinogenic Agents; Bezafibrate; Blotting, Western; Cell Differentiation; Cell Line; Chromans; Female; Keratinocytes; Linoleic Acid; Mice; Mice, Inbred SENCAR; Papilloma; Peroxisome Proliferators; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Skin; Skin Neoplasms; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone; Up-Regulation | 2000 |
Delayed activation of PPARgamma by LPS and IFN-gamma attenuates the oxidative burst in macrophages.
Topics: Animals; Cell Line; Cell Survival; Cells, Cultured; Escherichia coli; Genes, Reporter; Humans; Hypoglycemic Agents; Interferon-gamma; Lipopolysaccharides; Luciferases; Macrophages; Mice; Microbodies; Monocytes; NG-Nitroarginine Methyl Ester; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Recombinant Proteins; Respiratory Burst; Rosiglitazone; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidinediones; Transcription Factors; Transfection | 2001 |
Regulation of cardiac and skeletal muscle malonyl-CoA decarboxylase by fatty acids.
Topics: Animals; Aorta; Blood Pressure; Body Weight; Carboxy-Lyases; Chromans; Constriction; Diabetes Mellitus, Experimental; Dietary Fats; Fasting; Fatty Acids; Fatty Acids, Nonesterified; Food; Gene Expression Regulation, Enzymologic; Heart; Male; Muscle, Skeletal; Myocardium; Organ Size; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone | 2001 |
Differential regulation of expression of genes encoding uncoupling proteins 2 and 3 in brown adipose tissue during lactation in mice.
Topics: Adipose Tissue, Brown; Animals; Bezafibrate; Carrier Proteins; Chromans; Dietary Fats; Female; Gene Expression Regulation; Ion Channels; Lactation; Litter Size; Membrane Transport Proteins; Mice; Mitochondrial Proteins; Pregnancy; Proteins; Pyrimidines; RNA, Messenger; Thiazoles; Thiazolidinediones; Troglitazone; Uncoupling Protein 2; Uncoupling Protein 3 | 2001 |
The nuclear receptor PPAR gamma is expressed by mouse T lymphocytes and PPAR gamma agonists induce apoptosis.
Topics: Animals; Antigen Presentation; Apoptosis; Cell Division; Cell Survival; Cells, Cultured; Chromans; Flow Cytometry; Immunohistochemistry; In Situ Nick-End Labeling; Ionomycin; Ligands; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Transgenic; Prostaglandin D2; Pyrimidines; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Specific Pathogen-Free Organisms; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone | 2001 |
Effect of PPAR activators on cytokine-stimulated cyclooxygenase-2 expression in human colorectal carcinoma cells.
Topics: Adenocarcinoma; Colorectal Neoplasms; Cyclooxygenase 2; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Isoenzymes; Ligands; Membrane Proteins; Models, Biological; Prostaglandin-Endoperoxide Synthases; Pyrimidines; Receptor Cross-Talk; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Signal Transduction; Thiazoles; Thiazolidinediones; Transcription Factors; Tumor Necrosis Factor-alpha | 2001 |
Identification of a peroxisome-proliferator-activated-receptor response element in the apolipoprotein E gene control region.
Topics: Animals; Apolipoproteins E; Astrocytoma; Base Sequence; Binding Sites; CCAAT-Enhancer-Binding Protein-beta; CCAAT-Enhancer-Binding Protein-delta; CCAAT-Enhancer-Binding Proteins; Cell Line; Consensus Sequence; DNA-Binding Proteins; Gene Expression Regulation; Glioblastoma; Introns; Luciferases; Macrophages; Microbodies; Molecular Sequence Data; Protein Biosynthesis; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; RNA, Messenger; Thiazoles; Thiazolidinediones; Transcription Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 2001 |
Inhibitors of arachidonic acid metabolism potentiate tumour necrosis factor-alpha-induced apoptosis in HL-60 cells.
Topics: Apoptosis; Arachidonic Acid; Caspase 3; Caspases; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytochrome c Group; Cytosol; Dose-Response Relationship, Drug; Drug Synergism; HL-60 Cells; Humans; Indomethacin; Isoenzymes; Masoprocol; Membrane Proteins; Peroxisome Proliferators; Phospholipases A; Phospholipases A2; Prostaglandin-Endoperoxide Synthases; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Tretinoin; Tumor Necrosis Factor-alpha | 2001 |
Differential regulation of adipocytokine mRNAs by rosiglitazone in db/db mice.
Topics: Adiponectin; Adrenergic beta-Agonists; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Female; Gene Expression Regulation; Hormones, Ectopic; Hypoglycemic Agents; Intercellular Signaling Peptides and Proteins; Mice; Mice, Obese; Nerve Growth Factor; Phenethylamines; Protein Biosynthesis; Proteins; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Resistin; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Tumor Necrosis Factor-alpha | 2001 |
Limited cooperation between peroxisome proliferator-activated receptors and retinoid X receptor agonists in sebocyte growth and development.
Topics: Animals; Cell Differentiation; Cell Division; Cells, Cultured; Chromans; Drug Synergism; Epoprostenol; Male; Protein Isoforms; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Calcitriol; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; RNA, Messenger; Sebaceous Glands; Stem Cells; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone | 2001 |
Regulation of cytokine expression by ligands of peroxisome proliferator activated receptors.
Topics: Adjuvants, Immunologic; Animals; Concanavalin A; Cytokines; Female; Interleukin-4; Ligands; Lymphocyte Activation; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Microbodies; Promoter Regions, Genetic; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Receptors, IgE; RNA, Messenger; Spleen; T-Lymphocytes; Thiazoles; Thiazolidinediones; Transcription Factors; Up-Regulation | 2002 |
PPAR activators as antiinflammatory mediators in human T lymphocytes: implications for atherosclerosis and transplantation-associated arteriosclerosis.
Topics: Anti-Inflammatory Agents; Arteriosclerosis; CD4-Positive T-Lymphocytes; Cells, Cultured; Fenofibrate; Graft Survival; Heart Transplantation; Humans; Interferon-gamma; Interleukin-2; Lymphocyte Activation; Peroxisome Proliferators; Pioglitazone; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Tumor Necrosis Factor-alpha | 2002 |
Effects of peroxisome proliferator-activated receptor agonists on LPS-induced neuronal death in mixed cortical neurons: associated with iNOS and COX-2.
Topics: Animals; Cell Culture Techniques; Cell Death; Chromans; Clofibrate; Cyclooxygenase 2; Dinoprostone; Electrophoretic Mobility Shift Assay; Escherichia coli; Immunohistochemistry; In Situ Nick-End Labeling; Isoenzymes; Lipopolysaccharides; Mice; Mice, Inbred ICR; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxisome Proliferators; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone | 2002 |
PPAR activators inhibit endothelial cell migration by targeting Akt.
Topics: Apoptosis; Blotting, Western; Cell Movement; Cells, Cultured; Chromans; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Inhibitors; Fenofibrate; Flavonoids; Humans; Hypoglycemic Agents; Hypolipidemic Agents; In Situ Nick-End Labeling; Lipid Metabolism; Lymphokines; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Peroxisome Proliferators; Phosphatidylinositol 3-Kinases; Phosphorylation; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Thiazoles; Thiazolidinediones; Time Factors; Transcription Factors; Troglitazone; Umbilical Veins; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Vasodilator Agents | 2002 |
Induction of apoptosis in human and rat glioma by agonists of the nuclear receptor PPARgamma.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; bcl-Associated Death Protein; Cadherins; Carrier Proteins; Cell Division; Cell Survival; DNA Fragmentation; Drug Evaluation, Preclinical; Glioma; Humans; Nuclear Proteins; Oligonucleotides, Antisense; Prostaglandin D2; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Pyrimidines; Rats; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Tumor Cells, Cultured | 2002 |
Ligands of the peroxisome proliferator-activated receptors (PPAR-gamma and PPAR-alpha) reduce myocardial infarct size.
Topics: Adult; Animals; Cardiotonic Agents; Cell Adhesion Molecules; Cell Line; Cells, Cultured; Chemokine CCL2; Clofibrate; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Ligands; Male; Membrane Proteins; Myocardial Infarction; Myocardial Reperfusion Injury; Pioglitazone; Prostaglandin D2; Prostaglandins A; Protein Isoforms; Pyrimidines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors | 2002 |
Peroxisome proliferator-activated receptor ligands negatively regulate the expression of the high-affinity IgE receptor Fc epsilon RI in human basophilic KU812 cells.
Topics: Basophils; Flow Cytometry; Histamine Release; Humans; Ligands; Mast Cells; Peroxisome Proliferators; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Receptors, IgE; RNA, Messenger; Thiazoles; Thiazolidinediones; Transcription Factors; Tumor Cells, Cultured | 2002 |
PPAR alpha stimulates the rat gastrin-producing cell.
Topics: Animals; Chromans; Clofibric Acid; Female; Fibric Acids; Gastric Mucosa; Gastrins; Ligands; Parietal Cells, Gastric; Peroxisome Proliferators; Pyrimidines; Rats; Rats, Inbred F344; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone | 2002 |
PPARalpha /gamma ragaglitazar eliminates fatty liver and enhances insulin action in fat-fed rats in the absence of hepatomegaly.
Topics: Animals; Dietary Fats; Fatty Liver; Glucose; Glucose Clamp Technique; Insulin; Insulin Resistance; Lipid Metabolism; Liver; Male; Muscle, Skeletal; Oxazines; Phenylpropionates; Pyrimidines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors | 2003 |
Activation of peroxisome proliferator-activated receptors in human airway smooth muscle cells has a superior anti-inflammatory profile to corticosteroids: relevance for chronic obstructive pulmonary disease therapy.
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Apoptosis; Blotting, Western; Cell Division; Cells, Cultured; Dexamethasone; DNA Fragmentation; Female; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Inhibitors; Humans; Interleukin-1; Ligands; Male; Middle Aged; Muscle, Smooth; Peroxisomes; Prostaglandin D2; Protein Isoforms; Pulmonary Disease, Chronic Obstructive; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiazoles; Thiazolidinediones; Trachea; Transcription Factors | 2003 |
Increased expression of the lipocalin 24p3 as an apoptotic mechanism for MK886.
Topics: Acute-Phase Proteins; Animals; Apoptosis; Carcinogens; Caspase 3; Caspases; Gene Expression Regulation; Indoles; Lipocalin-2; Lipocalins; Lipoxygenase Inhibitors; Mice; Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Pyrimidines; Thiazoles; Thiazolidinediones | 2003 |
Activation-induced PPARgamma expression sensitizes primary human T cells toward apoptosis.
Topics: Apoptosis; Cysteine Proteinase Inhibitors; Gene Expression Regulation; Humans; Hydrazines; Jurkat Cells; Lymphocyte Activation; Lymphopenia; Nitrogen Oxides; Phytohemagglutinins; Promoter Regions, Genetic; Prostaglandin D2; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocytes; Thiazoles; Thiazolidinediones; Transcription Factors | 2003 |
Peroxisome proliferator activated receptor (PPAR)alpha agonists inhibit hypertrophy of neonatal rat cardiac myocytes.
Topics: Animals; Animals, Newborn; Base Sequence; Cell Size; Cells, Cultured; Fenofibrate; Gene Expression; Heart Ventricles; Hypertrophy; Hypoglycemic Agents; Hypolipidemic Agents; Ligands; Molecular Sequence Data; Mutagenesis, Site-Directed; Myocytes, Cardiac; Natriuretic Peptide, Brain; Peroxisome Proliferators; Pyrimidines; Rats; Receptors, Cytoplasmic and Nuclear; Rosiglitazone; Sarcomeres; Thiazoles; Thiazolidinediones; Transcription Factors | 2003 |
Peroxisome proliferator-activated receptor delta activates fatty acid oxidation in cultured neonatal and adult cardiomyocytes.
Topics: Animals; Animals, Newborn; Cells, Cultured; DNA Primers; Fatty Acids; Gene Expression; Humans; Mice; Mice, Knockout; Myocytes, Cardiac; Oxidation-Reduction; Palmitates; Protein Isoforms; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Thiazoles; Transcription Factors; Transcriptional Activation | 2004 |
Effect of the peroxisome proliferator-activated receptor beta activator GW0742 in rat cultured cerebellar granule neurons.
Topics: Animals; Animals, Newborn; Cell Death; Cells, Cultured; Cerebellum; L-Lactate Dehydrogenase; Nerve Degeneration; Neurons; Neurotoxins; Potassium Deficiency; Proto-Oncogene Proteins c-jun; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Thiazoles; Transcription Factors | 2004 |
Oleoylethanolamide, an endogenous PPAR-alpha agonist, lowers body weight and hyperlipidemia in obese rats.
Topics: Animals; Body Weight; Butyrates; CD36 Antigens; Cholesterol; Coenzyme A Ligases; Eating; Endocannabinoids; Fatty Acid-Binding Proteins; Hepatocytes; Hyperlipidemias; Ion Channels; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondrial Proteins; Obesity; Oleic Acids; Phenylurea Compounds; PPAR alpha; Pyrimidines; Rats; Rats, Inbred WF; Rats, Zucker; RNA, Messenger; Thiazoles; Thiazolidinediones; Triglycerides; Uncoupling Protein 2 | 2005 |
Statins and PPARalpha agonists induce myotoxicity in differentiated rat skeletal muscle cultures but do not exhibit synergy with co-treatment.
Topics: Adenosine Triphosphate; Animals; Cell Death; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Induction; Fibrinolytic Agents; Gene Expression; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ion Channels; Membrane Transport Proteins; Mitochondrial Proteins; Muscle Fibers, Skeletal; Muscular Diseases; Myoblasts, Skeletal; Peroxisome Proliferator-Activated Receptors; Pyrimidines; Rats; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Time Factors; Uncoupling Protein 2 | 2005 |
Activation of PPARdelta inhibits cardiac fibroblast proliferation and the transdifferentiation into myofibroblasts.
Topics: Animals; Animals, Newborn; Cell Differentiation; Cell Proliferation; Cells, Cultured; Collagen; Fibroblasts; Fibrosis; Humans; Immunohistochemistry; Ligands; Myocytes, Cardiac; Peroxisome Proliferators; PPAR alpha; PPAR delta; PPAR gamma; Pyrimidines; Rats; Rats, Inbred Lew; Rosiglitazone; Thiazoles; Thiazolidinediones; Transduction, Genetic | 2007 |
A PPARs cross-talk concertedly commits C6 glioma cells to oligodendrocytes and induces enzymes involved in myelin synthesis.
Topics: Alkyl and Aryl Transferases; Animals; Cell Differentiation; Cell Line, Tumor; Cell Lineage; Enzyme Induction; Glioma; Lipid Metabolism; Mice; Myelin Sheath; Oligodendroglia; Peroxisome Proliferator-Activated Receptors; PPAR alpha; PPAR gamma; PPAR-beta; Pyrimidines; Rats; Receptor Cross-Talk; RNA Interference; RNA, Small Interfering; Rosiglitazone; Thiazoles; Thiazolidinediones; Time Factors; Transcription, Genetic; Transfection | 2008 |
PPAR alpha, more than PPAR delta, mediates the hepatic and skeletal muscle alterations induced by the PPAR agonist GW0742.
Topics: Animals; Dose-Response Relationship, Drug; Hepatomegaly; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle, Skeletal; Muscular Diseases; Organ Size; Peroxisomes; PPAR alpha; PPAR delta; Pyrimidines; Thiazoles | 2008 |
PPARgamma inhibits NF-kappaB-dependent transcriptional activation in skeletal muscle.
Topics: Animals; Cells, Cultured; Cytokines; Down-Regulation; Humans; Hypoglycemic Agents; Inflammation Mediators; Male; Mice; Middle Aged; Muscle, Skeletal; NF-kappa B; PPAR gamma; Pyrimidines; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcriptional Activation | 2009 |
Mouse carnitine-acylcarnitine translocase (CACT) is transcriptionally regulated by PPARalpha and PPARdelta in liver cells.
Topics: Animals; Base Sequence; Body Weight; Carnitine Acyltransferases; Carnitine O-Palmitoyltransferase; Cell Line, Tumor; Cytochrome P-450 Enzyme System; Fasting; Female; Gene Expression Regulation, Enzymologic; Humans; Liver; Luciferases; Male; Mice; Mice, Knockout; Molecular Sequence Data; Mutation; PPAR alpha; PPAR delta; Promoter Regions, Genetic; Pyrimidines; Reverse Transcriptase Polymerase Chain Reaction; Thiazoles; Transcription, Genetic | 2009 |
Activation of PPAR α and PPAR β/δ regulates Sertoli cell metabolism.
Topics: Acetyl-CoA Carboxylase; Acyl-CoA Dehydrogenase; Animals; Carnitine O-Palmitoyltransferase; CD36 Antigens; Fatty Acids; Gene Expression Regulation; Glucose; L-Lactate Dehydrogenase; Lactates; Male; Models, Biological; Phosphorylation; PPAR alpha; PPAR delta; PPAR-beta; Pyrimidines; Pyruvate Dehydrogenase Complex; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sertoli Cells; Thiazoles | 2014 |
Aminothiazole-featured pirinixic acid derivatives as dual 5-lipoxygenase and microsomal prostaglandin E2 synthase-1 inhibitors with improved potency and efficiency in vivo.
Topics: Animals; Arachidonate 5-Lipoxygenase; Binding Sites; Drug Design; Humans; Hydrophobic and Hydrophilic Interactions; Inhibitory Concentration 50; Intramolecular Oxidoreductases; Lipoxygenase Inhibitors; Male; Mice; Microsomes; Models, Molecular; Peritonitis; Prostaglandin-E Synthases; Protein Conformation; Pyrimidines; Structure-Activity Relationship; Thiazoles; Zymosan | 2013 |
Identification of pirinixic acid derivatives bearing a 2-aminothiazole moiety combines dual PPARα/γ activation and dual 5-LO/mPGES-1 inhibition.
Topics: Arachidonate 5-Lipoxygenase; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Intramolecular Oxidoreductases; Models, Molecular; Molecular Structure; PPAR alpha; PPAR gamma; Prostaglandin-E Synthases; Pyrimidines; Structure-Activity Relationship; Thiazoles | 2014 |
Cardiomyocyte lipotoxicity is mediated by Il-6 and causes down-regulation of PPARs.
Topics: Acetylcarnitine; Animals; Animals, Newborn; Carnitine O-Palmitoyltransferase; Cell Death; Cells, Cultured; Cytokines; Down-Regulation; Gene Expression Regulation; Interleukin-6; Myocytes, Cardiac; Oleic Acid; Palmitates; PPAR alpha; PPAR delta; Pyrimidines; Rats, Sprague-Dawley; Thiazoles | 2015 |
Genomewide comparison of the inducible transcriptomes of nuclear receptors CAR, PXR and PPARα in primary human hepatocytes.
Topics: Adult; Constitutive Androstane Receptor; Cytochrome P-450 Enzyme System; Female; Gene Expression Profiling; Gene Expression Regulation; Gene Ontology; Genome-Wide Association Study; Hepatocytes; Humans; Inactivation, Metabolic; Ligands; Male; Metabolic Networks and Pathways; Middle Aged; Molecular Sequence Annotation; Oximes; PPAR alpha; Pregnane X Receptor; Primary Cell Culture; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Rifampin; Signal Transduction; Thiazoles; Transcriptome | 2016 |
Characterization of the Mouse and Human Monoacylglycerol O-Acyltransferase 1 (Mogat1) Promoter in Human Kidney Proximal Tubule and Rat Liver Cells.
Topics: Acyltransferases; Anilides; Animals; Blotting, Northern; Caco-2 Cells; Cell Line; Cell Line, Tumor; Chromatin Immunoprecipitation; Computational Biology; HT29 Cells; Humans; Kidney Tubules, Proximal; Liver; Mice; Oxazoles; PPAR alpha; Promoter Regions, Genetic; Pyrimidines; Rats; Real-Time Polymerase Chain Reaction; Rosiglitazone; Sulfones; Thiazoles; Thiazolidinediones; Thiophenes; Tyrosine | 2016 |