pirinixic acid has been researched along with rifampin in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Amaral, K; Black, C; Bradford, BU; Ferguson, SS; Freeman, K; Kaiser, R; Kosyk, O; LeCluyse, EL; Martinez, SM; Rusyn, I; Sandot, A; Soldatow, VY; Stewart, T; Witek, R | 1 |
| Burk, O; Damm, G; Kandel, BA; Schwab, M; Seehofer, D; Thomas, M; Winter, S; Zanger, UM | 1 |
6 other study(ies) available for pirinixic acid and rifampin
| Article | Year |
|---|---|
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Evaluation of an in vitro toxicogenetic mouse model for hepatotoxicity.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Antibiotics, Antitubercular; Cell Survival; Gene Expression; Hepatocytes; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred Strains; Models, Animal; Pyrimidines; Rifampin; Toxicity Tests | 2010 |
Genomewide comparison of the inducible transcriptomes of nuclear receptors CAR, PXR and PPARĪ± in primary human hepatocytes.
Topics: Adult; Constitutive Androstane Receptor; Cytochrome P-450 Enzyme System; Female; Gene Expression Profiling; Gene Expression Regulation; Gene Ontology; Genome-Wide Association Study; Hepatocytes; Humans; Inactivation, Metabolic; Ligands; Male; Metabolic Networks and Pathways; Middle Aged; Molecular Sequence Annotation; Oximes; PPAR alpha; Pregnane X Receptor; Primary Cell Culture; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Rifampin; Signal Transduction; Thiazoles; Transcriptome | 2016 |