Page last updated: 2024-08-16

pirinixic acid and prostaglandin d2

pirinixic acid has been researched along with prostaglandin d2 in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (13.04)18.2507
2000's16 (69.57)29.6817
2010's4 (17.39)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kliewer, SA; Lehmann, JM; Lenhard, JM; Morris, DC; Patel, I; Willson, TM1
Gebicke-Haerter, PJ; Kakimura, J; Kitamura, Y; Matsuoka, Y; Nomura, Y; Taniguchi, T1
Barberá, MJ; Carmona, MC; Giralt, M; Iglesias, R; Mampel, T; Valmaseda, A; Villarroya, F; Viñas, O1
Leung, JH; Libby, P; Luster, AD; Mach, F; Marx, N; Plutzky, J; Ransohoff, RM; Sarafi, MN; Sauty, A1
Anania, FA; Miyahara, T; Motomura, K; Rippe, R; Schrum, L; Tsukamoto, H; Willson, TM; Xiong, S; Yee, HF1
Banba, N; Hattori, Y; Hishinuma, A; Kakishita, H; Kasai, K; Matsumura, M; Motohashi, S; Sato, N1
Harris, SG; Phipps, RP1
Janabi, N1
Feinstein, D; Grommes, C; Heneka, MT; Klockgether, T; Koenigsknecht, J; Kraus, JA; Landreth, G; Schlegel, U; Zander, T1
Chatterjee, PK; Cuzzocrea, S; Hattori, Y; McDonald, MC; Mota-Filipe, H; Pisano, B; Thiemermann, C; Wayman, NS1
Belvisi, MG; Bishop-Bailey, D; Mitchell, JA; Patel, HJ; Yacoub, MH1
Fernando, R; Moorhead, JF; Powis, SH; Ruan, XZ; Varghese, Z; Wheeler, DC1
Brüne, B; Tautenhahn, A; von Knethen, A1
Del Rizzo, DF; Litchie, B; Moon, MC; Taylor, CG; Yurkova, N; Zahradka, P1
Afif, H; Cheng, S; Fahmi, H; Farrajota, K; Lavigne, M; Li, X; Martel-Pelletier, J; Pelletier, JP1
Corbett, L; Knox, AJ; Nie, M; Pang, L1
Abu-Ghazaleh, R; Avis, I; Martínez, A; Mayburd, A; Mulshine, JL; Ondrey, F; Tauler, J; Zudaire, E1
Chen, TP; Lee, CH; Lin, PJ; Lin, YM; Wu, YC; Yeh, CH1
Chadburn, A; Csernus, B; Hyjek, E; Jo, SH; Liu, Y; Wang, YL; Yang, C1
Gerner, C; Gruber, S; Haudek-Prinz, V; Hofstätter, E; Jonak, C; Klepeisz, P; Kunstfeld, R; Paulitschke, V; Pehamberger, H; Petzelbauer, P; Schicher, N1
Bogacka, I; Bogacki, M; Chojnowska, K; Kurzyńska, A2
Cevey, Á; Gómez, MI; González, CD; Goren, NB; Mirkin, GA; Penas, F; Sales, ME; Vera, M1

Other Studies

23 other study(ies) available for pirinixic acid and prostaglandin d2

ArticleYear
A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation.
    Cell, 1995, Dec-01, Volume: 83, Issue:5

    Topics: Adipocytes; Animals; Binding, Competitive; Cell Differentiation; Cells, Cultured; Fibroblasts; Hypoglycemic Agents; Ligands; Mice; Microbodies; Prostaglandin D2; Prostaglandins; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Rosiglitazone; Signal Transduction; Thiazoles; Thiazolidinediones; Transcription Factors; Transcriptional Activation

1995
Activators of peroxisome proliferator-activated receptor-gamma (PPARgamma) inhibit inducible nitric oxide synthase expression but increase heme oxygenase-1 expression in rat glial cells.
    Neuroscience letters, 1999, Mar-05, Volume: 262, Issue:2

    Topics: Alitretinoin; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Cells, Cultured; Dinoprostone; Enzyme Induction; Gene Expression Regulation, Enzymologic; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Interferon-gamma; Lipopolysaccharides; Neuroglia; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Prostaglandin D2; Pyrimidines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Tretinoin

1999
Opposite regulation of PPAR-alpha and -gamma gene expression by both their ligands and retinoic acid in brown adipocytes.
    Molecular and cellular endocrinology, 1999, Aug-20, Volume: 154, Issue:1-2

    Topics: Adipocytes; Adipose Tissue, Brown; Animals; Cell Differentiation; Cells, Cultured; DNA-Binding Proteins; Gene Expression Regulation; Ligands; Male; Mice; Prostaglandin D2; Protein Isoforms; Pyrimidines; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Transcription Factors; Tretinoin

1999
Peroxisome proliferator-activated receptor-gamma activators inhibit IFN-gamma-induced expression of the T cell-active CXC chemokines IP-10, Mig, and I-TAC in human endothelial cells.
    Journal of immunology (Baltimore, Md. : 1950), 2000, Jun-15, Volume: 164, Issue:12

    Topics: Chemokine CXCL10; Chemokine CXCL11; Chemokine CXCL9; Chemokines, CXC; Chemotaxis; Docosahexaenoic Acids; Dose-Response Relationship, Immunologic; Eicosapentaenoic Acid; Endothelium, Vascular; Humans; Intercellular Signaling Peptides and Proteins; Interferon-gamma; Microbodies; NF-kappa B; Promoter Regions, Genetic; Prostaglandin D2; Pyrimidines; Receptors, Chemokine; Receptors, CXCR3; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Saphenous Vein; T-Lymphocytes; Transcription Factors

2000
Peroxisome proliferator-activated receptors and hepatic stellate cell activation.
    The Journal of biological chemistry, 2000, Nov-17, Volume: 275, Issue:46

    Topics: Animals; Cell Size; Cell Survival; Cells, Cultured; Collagen; DNA; Gene Expression Regulation; Liver; Liver Cirrhosis, Biliary; Liver Cirrhosis, Experimental; Male; Promoter Regions, Genetic; Prostaglandin D2; Protein Binding; Protein Isoforms; Pyrimidines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Tumor Necrosis Factor-alpha

2000
15-Deoxy-Delta(12,14)-prostaglandin J(2) facilitates thyroglobulin production by cultured human thyrocytes.
    American journal of physiology. Cell physiology, 2000, Volume: 279, Issue:6

    Topics: Anticholesteremic Agents; Arsenites; Bucladesine; Cells, Cultured; Chromans; Cyclic AMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fetal Proteins; Gene Expression Regulation, Enzymologic; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Hypoglycemic Agents; Ligands; Membrane Proteins; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Pioglitazone; Prostaglandin D2; Pyrimidines; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Sodium Compounds; Thiazoles; Thiazolidinediones; Thyroglobulin; Thyroid Gland; Thyrotropin; Transcription Factors; Troglitazone

2000
The nuclear receptor PPAR gamma is expressed by mouse T lymphocytes and PPAR gamma agonists induce apoptosis.
    European journal of immunology, 2001, Volume: 31, Issue:4

    Topics: Animals; Antigen Presentation; Apoptosis; Cell Division; Cell Survival; Cells, Cultured; Chromans; Flow Cytometry; Immunohistochemistry; In Situ Nick-End Labeling; Ionomycin; Ligands; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Transgenic; Prostaglandin D2; Pyrimidines; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Specific Pathogen-Free Organisms; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone

2001
Selective inhibition of cyclooxygenase-2 expression by 15-deoxy-Delta(12,14)(12,14)-prostaglandin J(2) in activated human astrocytes, but not in human brain macrophages.
    Journal of immunology (Baltimore, Md. : 1950), 2002, May-01, Volume: 168, Issue:9

    Topics: Anti-Inflammatory Agents; Astrocytes; Brain; Cells, Cultured; Clofibrate; Cyclooxygenase 2; Cytokines; Gene Silencing; Humans; Isoenzymes; Membrane Proteins; Microglia; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Promoter Regions, Genetic; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Pyrimidines; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Transcription Factors

2002
Induction of apoptosis in human and rat glioma by agonists of the nuclear receptor PPARgamma.
    Journal of neurochemistry, 2002, Volume: 81, Issue:5

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; bcl-Associated Death Protein; Cadherins; Carrier Proteins; Cell Division; Cell Survival; DNA Fragmentation; Drug Evaluation, Preclinical; Glioma; Humans; Nuclear Proteins; Oligonucleotides, Antisense; Prostaglandin D2; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Pyrimidines; Rats; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Tumor Cells, Cultured

2002
Ligands of the peroxisome proliferator-activated receptors (PPAR-gamma and PPAR-alpha) reduce myocardial infarct size.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2002, Volume: 16, Issue:9

    Topics: Adult; Animals; Cardiotonic Agents; Cell Adhesion Molecules; Cell Line; Cells, Cultured; Chemokine CCL2; Clofibrate; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Ligands; Male; Membrane Proteins; Myocardial Infarction; Myocardial Reperfusion Injury; Pioglitazone; Prostaglandin D2; Prostaglandins A; Protein Isoforms; Pyrimidines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors

2002
Activation of peroxisome proliferator-activated receptors in human airway smooth muscle cells has a superior anti-inflammatory profile to corticosteroids: relevance for chronic obstructive pulmonary disease therapy.
    Journal of immunology (Baltimore, Md. : 1950), 2003, Mar-01, Volume: 170, Issue:5

    Topics: Adolescent; Adult; Anti-Inflammatory Agents; Apoptosis; Blotting, Western; Cell Division; Cells, Cultured; Dexamethasone; DNA Fragmentation; Female; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Inhibitors; Humans; Interleukin-1; Ligands; Male; Middle Aged; Muscle, Smooth; Peroxisomes; Prostaglandin D2; Protein Isoforms; Pulmonary Disease, Chronic Obstructive; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiazoles; Thiazolidinediones; Trachea; Transcription Factors

2003
PPAR agonists protect mesangial cells from interleukin 1beta-induced intracellular lipid accumulation by activating the ABCA1 cholesterol efflux pathway.
    Journal of the American Society of Nephrology : JASN, 2003, Volume: 14, Issue:3

    Topics: Anticholesteremic Agents; Antineoplastic Agents; ATP-Binding Cassette Transporters; Bezafibrate; Biological Transport; Cell Line, Transformed; Cholesterol; DNA-Binding Proteins; Glomerular Mesangium; Humans; Hydroxycholesterols; Hypolipidemic Agents; Interleukin-1; Liver X Receptors; Orphan Nuclear Receptors; Prostaglandin D2; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Transcription Factors

2003
Activation-induced PPARgamma expression sensitizes primary human T cells toward apoptosis.
    Journal of leukocyte biology, 2003, Volume: 73, Issue:5

    Topics: Apoptosis; Cysteine Proteinase Inhibitors; Gene Expression Regulation; Humans; Hydrazines; Jurkat Cells; Lymphocyte Activation; Lymphopenia; Nitrogen Oxides; Phytohemagglutinins; Promoter Regions, Genetic; Prostaglandin D2; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocytes; Thiazoles; Thiazolidinediones; Transcription Factors

2003
Activation of peroxisome proliferator-activated receptors alpha and gamma1 inhibits human smooth muscle cell proliferation.
    Molecular and cellular biochemistry, 2003, Volume: 246, Issue:1-2

    Topics: Arteriosclerosis; Base Sequence; Cell Division; Cells, Cultured; Humans; Immunohistochemistry; Muscle, Smooth, Vascular; Prostaglandin D2; Pyrimidines; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Transcription Factors

2003
Activation of peroxisome proliferator-activated receptor gamma inhibits interleukin-1beta-induced membrane-associated prostaglandin E2 synthase-1 expression in human synovial fibroblasts by interfering with Egr-1.
    The Journal of biological chemistry, 2004, May-21, Volume: 279, Issue:21

    Topics: Amino Acid Motifs; Anilides; Binding Sites; Blotting, Western; Cell Division; Cell Nucleus; Chromans; DNA-Binding Proteins; DNA, Complementary; Dose-Response Relationship, Drug; Early Growth Response Protein 1; Fibroblasts; Genes, Dominant; Genes, Reporter; Humans; Immediate-Early Proteins; Immunologic Factors; Inflammation; Interleukin-1; Intramolecular Oxidoreductases; Ligands; Peroxisome Proliferators; Plasmids; Promoter Regions, Genetic; Prostaglandin D2; Prostaglandin-E Synthases; Protein Binding; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; RNA; Synovial Membrane; Thiazolidinediones; Time Factors; Transcription Factors; Transcription, Genetic; Transfection; Troglitazone

2004
Differential regulation of chemokine expression by peroxisome proliferator-activated receptor gamma agonists: interactions with glucocorticoids and beta2-agonists.
    The Journal of biological chemistry, 2005, Jan-28, Volume: 280, Issue:4

    Topics: Adrenergic beta-Agonists; Albuterol; Androstadienes; Blotting, Western; Cell Line; Chemokine CCL11; Chemokine CCL2; Chemokines; Chemokines, CC; Chromans; Chromatin; Chromatin Immunoprecipitation; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Fluticasone; Gene Expression Regulation; Glucocorticoids; Humans; Immunoprecipitation; Interleukin-8; Plasmids; PPAR alpha; PPAR gamma; Promoter Regions, Genetic; Prostaglandin D2; Protein Binding; Pyrimidines; Receptors, Glucocorticoid; Reverse Transcriptase Polymerase Chain Reaction; RNA; Salmeterol Xinafoate; Thiazolidinediones; Transcription, Genetic; Transfection; Troglitazone; Tumor Necrosis Factor-alpha

2005
Inhibitors of the arachidonic acid pathway and peroxisome proliferator-activated receptor ligands have superadditive effects on lung cancer growth inhibition.
    Cancer research, 2005, May-15, Volume: 65, Issue:10

    Topics: Acetophenones; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Arachidonic Acid; Caspases; Cell Growth Processes; Cell Line, Tumor; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Indoles; Isotretinoin; Ligands; Lung Neoplasms; Peroxisome Proliferator-Activated Receptors; Prostaglandin D2; Pyrimidines; Retinoid X Receptor alpha; RNA, Messenger; Tetrazoles; Thiazolidinediones

2005
Cardiomyocytic apoptosis following global cardiac ischemia and reperfusion can be attenuated by peroxisome proliferator-activated receptor alpha but not gamma activators.
    Shock (Augusta, Ga.), 2006, Volume: 26, Issue:3

    Topics: Animals; Apoptosis; Cardiopulmonary Bypass; Caspase 3; Caspases; Cell Adhesion Molecules; Cytokines; Fas Ligand Protein; Gene Expression; Heart; Heart Arrest, Induced; In Situ Nick-End Labeling; Male; Membrane Glycoproteins; Myocardial Reperfusion Injury; Myocytes, Cardiac; NF-kappa B; Peroxidase; Peroxisome Proliferators; PPAR alpha; PPAR gamma; Prostaglandin D2; Proto-Oncogene Proteins c-jun; Pyrimidines; Rabbits; Troponin I; Tumor Necrosis Factors

2006
Activation of peroxisome proliferator-activated receptor gamma contributes to the survival of T lymphoma cells by affecting cellular metabolism.
    The American journal of pathology, 2007, Volume: 170, Issue:2

    Topics: Adenosine Triphosphate; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Fatty Acids; Glucose; Humans; Hypoglycemic Agents; Ligands; Lymphoma, T-Cell; Membrane Potential, Mitochondrial; Mitochondria; Neoplasm Proteins; Peroxisome Proliferators; PPAR gamma; Prostaglandin D2; Pyrimidines; Reactive Oxygen Species; Rosiglitazone; Thiazolidinediones

2007
Proteome analysis identified the PPARγ ligand 15d-PGJ2 as a novel drug inhibiting melanoma progression and interfering with tumor-stroma interaction.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chromans; Humans; Melanoma; PPAR gamma; Prostaglandin D2; Proteome; Pyrimidines; Thiazolidinediones; Troglitazone

2012
The involvement of peroxisome proliferator activated receptors (PPARs) in prostaglandin F2α production by porcine endometrium.
    Reproductive biology, 2013, Volume: 13, Issue:4

    Topics: Analysis of Variance; Anilides; Animals; Benzamides; Culture Media; Dinoprost; DNA Primers; Endometrium; Estrous Cycle; Female; Indoles; Peroxisome Proliferator-Activated Receptors; Phenoxyacetates; Pregnancy; Prostaglandin D2; Pyridines; Pyrimidines; Radioimmunoassay; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Rosiglitazone; Swine; Thiazolidinediones

2013
Peroxisome proliferator activated receptor ligands affect progesterone and 17β-estradiol secretion by porcine corpus luteum during early pregnancy.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2014, Volume: 65, Issue:5

    Topics: 3-Hydroxysteroid Dehydrogenases; Anilides; Animals; Benzamides; Corpus Luteum; Estradiol; Estrous Cycle; Female; Gene Expression; Indoles; Ligands; Peroxisome Proliferator-Activated Receptors; Phenoxyacetates; Pregnancy; Progesterone; Prostaglandin D2; Pyridines; Pyrimidines; RNA, Messenger; Rosiglitazone; Swine; Thiazolidinediones

2014
Treatment in vitro with PPARα and PPARγ ligands drives M1-to-M2 polarization of macrophages from T. cruzi-infected mice.
    Biochimica et biophysica acta, 2015, Volume: 1852, Issue:5

    Topics: Animals; Arginase; beta-N-Acetylhexosaminidases; Blotting, Western; Cells, Cultured; Chagas Disease; Cytokines; Host-Pathogen Interactions; Inflammation Mediators; Lectins; Ligands; Macrophage Activation; Macrophages; Male; Mice, Inbred BALB C; Microscopy, Fluorescence; Nitric Oxide Synthase Type II; Phagocytosis; PPAR alpha; PPAR gamma; Prostaglandin D2; Pyrimidines; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Transforming Growth Factor beta; Trypanosoma cruzi

2015