pirinixic acid has been researched along with phenobarbital in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (8.70) | 18.7374 |
| 1990's | 9 (39.13) | 18.2507 |
| 2000's | 9 (39.13) | 29.6817 |
| 2010's | 3 (13.04) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Keenan, KP; O'Brien, KA; Smith, PF | 1 |
| Cattley, RC; Popp, JA | 1 |
| Bender, PE; Eckardt, RD; Leonard, TB; Newton, JF; Romano, MC; Straub, KM | 1 |
| Cattley, RC; Glover, SE | 1 |
| Cattley, RC; Glover, SE; Miller, RT; Murkofsky, RL; Popp, JA | 1 |
| Beamand, JA; Charzat, C; Lake, BG; Price, RJ; Renwick, AB; Tredger, JM | 1 |
| James, NH; Roberts, RA | 1 |
| Brierley, CH; Burchell, B; Clarke, D; Hsu, MH; Johnson, EF; Senafi, SB | 1 |
| Alworth, WL; English, N; Hughes, V; Kang, L; Palmer, CN; Wolf, CR | 1 |
| Anderson, SP; Cattley, RC; Christensen, JG; Corton, JC; Fox, TR; Goldsworthy, TL; Gonzales, AJ; Healy, LN; Malarkey, DE; Romach, EH | 1 |
| Butterworth, BE; Goldsworthy, SM; Goldsworthy, TL; Sprankle, CS | 1 |
| Deutsch, WA; Hegde, V; Kukreja, A; Shane, B | 1 |
| Cunningham, ML; Ganesh, L; Shane, BS; Singh, VK | 1 |
| Isenberg, JS; Kamendulis, LM; Klaunig, JE; Lington, AW; Pugh, G; Smith, JH | 1 |
| Afshari, CA; Barrett, JC; Bennett, L; Blanchard, K; Bushel, PR; DiSorbo, O; Hamadeh, HK; Jayadev, S; Martin, K; Paules, RS; Sieber, S; Stoll, R; Tennant, R | 1 |
| Ball, SE; Kao, J; Lake, BG; Pan, J; Price, RJ; Renwick, AB; Scatina, JA; Xiang, Q | 1 |
| Adler, R; Amacher, DE; Herath, A; Townsend, RR | 1 |
| Bradford, BU; Cunningham, ML; Gatti, DM; Kosyk, O; Ross, PK; Rusyn, I; Woods, CG | 1 |
| Andres, J; Bode, LM; Carnevali, LC; Hirsch-Ernst, KI; Kuna, M; Neuschäfer-Rube, F; Püschel, GP; Wieneke, N | 1 |
| Argikar, UA; Larson, EE; Remmel, RP; Senekeo-Effenberger, K; Tukey, RH | 1 |
| Benoki, S; Kodama, S; Miyata, M; Numakura, Y; Shizu, R; Yamazoe, Y; Yoshinari, K | 1 |
23 other study(ies) available for pirinixic acid and phenobarbital
| Article | Year |
|---|---|
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Evaluation of bromodeoxyuridine labeling in hepatomegaly produced by peroxisomal proliferation or P-450 induction in rodents.
Topics: Animals; Anticholesteremic Agents; Bromodeoxyuridine; Cell Division; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Hepatomegaly; Liver; Male; Mice; Mice, Inbred Strains; Microbodies; Phenobarbital; Pyrimidines; Rats; Rats, Inbred Strains; Reference Values | 1991 |
Differences between the promoting activities of the peroxisome proliferator WY-14,643 and phenobarbital in rat liver.
Topics: Adenosine Triphosphatases; Animals; Anticholesteremic Agents; Carcinogens; Diethylnitrosamine; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Experimental; Male; Microbodies; Phenobarbital; Precancerous Conditions; Pyrimidines; Rats; Rats, Inbred F344; Time Factors | 1989 |
Biochemical characterization of hepatic microsomal leukotriene B4 hydroxylases.
Topics: Animals; Benzoflavones; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 4; Kinetics; Leukotriene B4; Male; Mass Spectrometry; Methylcholanthrene; Metyrapone; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Proadifen; Pyrimidines; Rats; Rats, Inbred F344; Temperature | 1987 |
Elevated 8-hydroxydeoxyguanosine in hepatic DNA of rats following exposure to peroxisome proliferators: relationship to carcinogenesis and nuclear localization.
Topics: Animals; Body Weight; Carcinogens; Cell Nucleus; Clofibric Acid; Diethylhexyl Phthalate; DNA; Guanosine; Liver; Male; Microbodies; Organ Size; Phenobarbital; Pyrimidines; Rats; Rats, Inbred F344 | 1993 |
Effect of regeneration and hyperplasia on levels of DNA base oxidation in rat liver.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Carbon Tetrachloride; Cell Division; Deoxyguanosine; Hyperplasia; Liver; Liver Regeneration; Male; Oxidation-Reduction; Phenobarbital; Pyrimidines; Rats; Rats, Inbred F344 | 1993 |
Induction of cytochrome P450 isoenzymes in cultured precision-cut rat and human liver slices.
Topics: Animals; Aroclors; Benzoflavones; beta-Naphthoflavone; Chlorodiphenyl (54% Chlorine); Clofenapate; Clofibric Acid; Culture Techniques; Cytochrome P-450 Enzyme System; Enzyme Induction; Fibric Acids; Humans; Isoenzymes; Liver; Male; Microbodies; Phenobarbital; Pyrimidines; Rats; Rats, Sprague-Dawley | 1996 |
Species differences in response to peroxisome proliferators correlate in vitro with induction of DNA synthesis rather than suppression of apoptosis.
Topics: Animals; Apoptosis; Blood; Clofenapate; Cricetinae; Culture Media; DNA Damage; DNA Replication; Dogs; Guinea Pigs; Homeostasis; Male; Mice; Microbodies; Nafenopin; Phenobarbital; Pyrimidines; Rats; Species Specificity; Transforming Growth Factors | 1996 |
Regulation of the human bilirubin UDP-glucuronosyltransferase gene.
Topics: Base Sequence; Binding Sites; Cells, Cultured; Consensus Sequence; Gene Expression Regulation; Genes, Reporter; Glucuronosyltransferase; Humans; Microsomes, Liver; Molecular Sequence Data; Phenobarbital; Pyrimidines; TATA Box; Transcription Factors; Tretinoin; Xenobiotics | 1996 |
Fatty acid signals in Bacillus megaterium are attenuated by cytochrome P-450-mediated hydroxylation.
Topics: Bacillus megaterium; Bacterial Proteins; Barbiturates; Cloning, Molecular; Cytochrome P-450 Enzyme System; Enzyme Induction; Hydroxylation; Kinetics; Microbodies; Mixed Function Oxygenases; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Pentobarbital; Phenobarbital; Phytanic Acid; Pyrimidines; Recombinant Proteins; Repressor Proteins; Secobarbital; Substrate Specificity; Transcription Factors | 1997 |
Altered bcl-2 family expression during non-genotoxic hepatocarcinogenesis in mice.
Topics: Adenoma; Animals; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Carcinogens; Carcinoma; Carrier Proteins; Chlordan; DNA-Binding Proteins; Liver Neoplasms, Experimental; Male; Mice; Neoplasm Proteins; Phenobarbital; Phenotype; Polychlorinated Dibenzodioxins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Pyrimidines; Transcription Factors | 1999 |
Expression of myc, fos and Ha-ras associated with chemically induced cell proliferation in the rat liver.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Body Weight; Carcinogens; Cell Division; Gene Expression; Genes, fos; Genes, myc; Genes, ras; Liver; Male; Organ Size; Phenobarbital; Pyrimidines; Rats; Rats, Inbred F344 | 1994 |
Phenobarbital, oxazepam and Wyeth 14,643 cause DNA damage as measured by the Comet assay.
Topics: Carcinogens; Comet Assay; DNA Damage; Humans; Hypnotics and Sedatives; K562 Cells; Oxazepam; Phenobarbital; Pyrimidines; Tumor Cells, Cultured | 2001 |
Comparison of the mutant frequencies and mutation spectra of three non-genotoxic carcinogens, oxazepam, phenobarbital, and Wyeth 14,643, at the lambdacII locus in Big Blue transgenic mice.
Topics: Animals; Carcinogens; DNA; Male; Mice; Mice, Transgenic; Mutation; Oxazepam; Phenobarbital; Pyrimidines; Transcription Factors; Viral Proteins | 2001 |
Comparative effects of phthalate monoesters on gap junctional intercellular communication and peroxisome proliferation in rodent and primate hepatocytes.
Topics: Adult; Animals; Cell Communication; Cells, Cultured; Cricetinae; Dose-Response Relationship, Drug; Esters; Female; Gap Junctions; Hepatocytes; Humans; Macaca fascicularis; Male; Mice; Mice, Inbred Strains; Peroxisome Proliferators; Peroxisomes; Phenobarbital; Phthalic Acids; Pyrimidines; Rats; Rats, Inbred F344; Species Specificity; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 2002 |
Gene expression analysis reveals chemical-specific profiles.
Topics: Animals; Clofibrate; Computational Biology; DNA, Complementary; Gemfibrozil; Gene Expression; Gene Expression Profiling; Genomics; Liver; Male; Oligonucleotide Array Sequence Analysis; Pattern Recognition, Automated; Peroxisome Proliferators; Phenobarbital; Pyrimidines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2002 |
Use of a quantitative real-time reverse transcription-polymerase chain reaction method to study the induction of CYP1A, CYP2B and CYP4A forms in precision-cut rat liver slices.
Topics: Animals; Aroclors; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 4; Environmental Pollutants; Excitatory Amino Acid Antagonists; Liver; Male; Mutagens; Phenobarbital; Pyrimidines; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Time Factors; Up-Regulation | 2002 |
Use of proteomic methods to identify serum biomarkers associated with rat liver toxicity or hypertrophy.
Topics: 1-Naphthylisothiocyanate; Acetaminophen; Animals; Biomarkers; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertrophy; Liver Diseases; Male; Methylcellulose; Organ Size; Phenobarbital; Proteomics; Pyrimidines; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity | 2005 |
Time-course comparison of xenobiotic activators of CAR and PPARalpha in mouse liver.
Topics: Animals; Azo Compounds; Biotransformation; Blood Chemical Analysis; Carcinogens; Constitutive Androstane Receptor; DNA, Complementary; Hypnotics and Sedatives; Immunohistochemistry; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oligonucleotide Array Sequence Analysis; Phenobarbital; PPAR alpha; Proliferating Cell Nuclear Antigen; Pyrimidines; Receptors, Cytoplasmic and Nuclear; RNA; Transcription Factors; Xenobiotics | 2009 |
Synergistic acceleration of thyroid hormone degradation by phenobarbital and the PPAR alpha agonist WY14643 in rat hepatocytes.
Topics: Animals; Cells, Cultured; Drug Synergism; Hepatocytes; Male; Phenobarbital; PPAR alpha; Pyrimidines; Rats; Rats, Wistar; Thyroxine; Triiodothyronine | 2009 |
Studies on induction of lamotrigine metabolism in transgenic UGT1 mice.
Topics: Animals; Anticonvulsants; Chromatography, High Pressure Liquid; Enzyme Induction; Female; GABA Modulators; Gas Chromatography-Mass Spectrometry; Glucuronosyltransferase; Hepatocytes; Humans; Kinetics; Lamotrigine; Male; Metabolic Clearance Rate; Mice; Mice, Transgenic; Microsomes, Liver; Peroxisome Proliferator-Activated Receptors; Peroxisome Proliferators; Phenobarbital; Pregnenolone Carbonitrile; Pyrimidines; Triazines | 2009 |
Xenobiotic-induced hepatocyte proliferation associated with constitutive active/androstane receptor (CAR) or peroxisome proliferator-activated receptor α (PPARα) is enhanced by pregnane X receptor (PXR) activation in mice.
Topics: Animals; Cell Proliferation; Constitutive Androstane Receptor; Gene Expression Regulation; Hepatocytes; Injections, Intraperitoneal; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phenobarbital; PPAR alpha; Pregnane X Receptor; Pregnenolone Carbonitrile; Primary Cell Culture; Pyridines; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Signal Transduction; Xenobiotics | 2013 |