Compounds > pirinixic acid
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pirinixic acid and methapyrilene

pirinixic acid has been researched along with methapyrilene in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Anderson, NL; Cunningham, ML; Pippin, LL; Wenk, ML1
Kramer, K; O'Brien, PJ; Polley, SR; Slaughter, MR1
Chipman, JK; Mally, A1

Other Studies

5 other study(ies) available for pirinixic acid and methapyrilene

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
The hepatocarcinogen methapyrilene but not the analog pyrilamine induces sustained hepatocellular replication and protein alterations in F344 rats in a 13-week feed study.
    Toxicology and applied pharmacology, 1995, Volume: 131, Issue:2

    Topics: Administration, Oral; Animals; Body Weight; Carcinogens; Cell Division; Dose-Response Relationship, Drug; Liver; Male; Methapyrilene; Mitochondria, Liver; Proliferating Cell Nuclear Antigen; Protein Biosynthesis; Pyrilamine; Pyrimidines; Rats; Rats, Inbred F344

1995
Advantages of glutamate dehydrogenase as a blood biomarker of acute hepatic injury in rats.
    Laboratory animals, 2002, Volume: 36, Issue:3

    Topics: Acute Disease; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Biomarkers; Chemical and Drug Induced Liver Injury; Cyproterone; Dexamethasone; Glutamate Dehydrogenase; Hepatectomy; Isoniazid; L-Iditol 2-Dehydrogenase; Lead; Liver; Male; Methapyrilene; Nitrates; Pyrimidines; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity

2002
Non-genotoxic carcinogens: early effects on gap junctions, cell proliferation and apoptosis in the rat.
    Toxicology, 2002, Dec-02, Volume: 180, Issue:3

    Topics: Animals; Apoptosis; Body Weight; Carcinogens; Cell Division; Connexin 26; Connexins; Dose-Response Relationship, Drug; Down-Regulation; Female; Gap Junction beta-1 Protein; Gap Junctions; Hepatocytes; Immunohistochemistry; Kidney; Liver; Male; Methapyrilene; Pyrimidines; Rats; Rats, Inbred F344; Time Factors

2002