Compounds > pirinixic acid
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pirinixic acid and lamotrigine

pirinixic acid has been researched along with lamotrigine in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Argikar, U; Barbier, O; Bonzo, JA; Brace-Sinnokrak, E; Chen, S; Kaeding, J; Remmel, RP; Ritter, JK; Senekeo-Effenberger, K; Trottier, J; Tukey, RH; Yueh, MF1
Argikar, UA; Larson, EE; Remmel, RP; Senekeo-Effenberger, K; Tukey, RH1

Other Studies

3 other study(ies) available for pirinixic acid and lamotrigine

ArticleYear
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Expression of the human UGT1 locus in transgenic mice by 4-chloro-6-(2,3-xylidino)-2-pyrimidinylthioacetic acid (WY-14643) and implications on drug metabolism through peroxisome proliferator-activated receptor alpha activation.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:3

    Topics: Animals; Anticonvulsants; Cell Line; Gastrointestinal Tract; Gene Expression Regulation, Enzymologic; Glucuronosyltransferase; Hepatocytes; Humans; Lamotrigine; Liver; Male; Mice; Mice, Transgenic; Microsomes; Peroxisome Proliferators; PPAR alpha; Pyrimidines; Triazines

2007
Studies on induction of lamotrigine metabolism in transgenic UGT1 mice.
    Xenobiotica; the fate of foreign compounds in biological systems, 2009, Volume: 39, Issue:11

    Topics: Animals; Anticonvulsants; Chromatography, High Pressure Liquid; Enzyme Induction; Female; GABA Modulators; Gas Chromatography-Mass Spectrometry; Glucuronosyltransferase; Hepatocytes; Humans; Kinetics; Lamotrigine; Male; Metabolic Clearance Rate; Mice; Mice, Transgenic; Microsomes, Liver; Peroxisome Proliferator-Activated Receptors; Peroxisome Proliferators; Phenobarbital; Pregnenolone Carbonitrile; Pyrimidines; Triazines

2009