pirinixic acid has been researched along with l-165041 in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 8 (57.14) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Brown, PJ; Henke, BR; Sternbach, DD; Willson, TM | 1 |
| Altieri, F; Azzariti, A; Cervoni, L; Crestani, M; Di Giovanni, C; Fracchiolla, G; Gilardi, F; Giudici, M; Guerrini, U; Laghezza, A; Lavecchia, A; Loiodice, F; Mitro, N; Montanari, R; Paradiso, A; Piemontese, L; Pochetti, G; Porcelli, L; Simone, GM; Tortorella, P | 1 |
| Ammazzalorso, A; Amoroso, R; De Filippis, B; Di Giovanni, C; Fantacuzzi, M; Giampietro, L; Laghezza, A; Lavecchia, A; Linciano, P; Loiodice, F; Maccallini, C; Tortorella, P | 1 |
| Cerchia, C; Colantuoni, V; Convertini, P; Dal Piaz, F; Iacobazzi, V; Infantino, V; Laghezza, A; Lavecchia, A; Loiodice, F; Lupo, A; Piemontese, L; Sblano, S; Tortorella, P; Ziccardi, P | 1 |
| Ammazzalorso, A; Amoroso, R; Brunetti, L; Bruno, I; Cama, A; Capone, F; Cerchia, C; De Filippis, B; Fantacuzzi, M; Ferrante, C; Florio, R; Giampietro, L; Laghezza, A; Lavecchia, A; Loiodice, F; Maccallini, C; Recinella, L; Tortorella, P; Verginelli, F | 1 |
| Brunetti, L; Cerchia, C; Genovese, M; Gilardi, F; Laghezza, A; Lavecchia, A; Leuci, R; Loiodice, F; Paoli, P; Piemontese, L; Santi, A; Sblano, S; Thomas, A; Tortorella, P | 1 |
| Benéteau, N; Colpaert, FC; Delhon, A; Dupont-Passelaigue, E; Junquéro, D; Patoiseau, JF; Pezet, M; Rival, Y; Taillandier, T | 1 |
| Lerch, R; Montessuit, C; Papageorgiou, I; Pellieux, C | 1 |
| Jacobsson, A; Jörgensen, JA; Zadravec, D | 1 |
| Lerch, R; Montessuit, C; Papageorgiou, I | 1 |
| Bernd, A; Kaufmann, R; Kippenberger, S; Müller, J; Ochsendorf, F; Schuster, M; Thaçi, D; Zouboulis, CC | 1 |
| Bogacka, I; Bogacki, M; Gaglewska, M; Kurzynska, A; Wasielak, M | 1 |
| Bogacka, I; Bogacki, M; Chojnowska, K; Kurzyńska, A | 2 |
1 review(s) available for pirinixic acid and l-165041
| Article | Year |
|---|---|
The PPARs: from orphan receptors to drug discovery.
Topics: Animals; Diabetes Mellitus; Drug Design; Humans; Hyperlipidemias; Hypertension; Inflammation; Ligands; Models, Molecular; Neoplasms; Nuclear Proteins; Obesity; Receptors, Cytoplasmic and Nuclear; Transcription Factors | 2000 |
13 other study(ies) available for pirinixic acid and l-165041
| Article | Year |
|---|---|
Synthesis, characterization and biological evaluation of ureidofibrate-like derivatives endowed with peroxisome proliferator-activated receptor activity.
Topics: Adipocytes; Animals; Antineoplastic Agents; Benzoxazoles; Body Weight; Calorimetry; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Proliferation; Crystallography, X-Ray; Drug Partial Agonism; Drug Screening Assays, Antitumor; Fibric Acids; Fibroblasts; Gene Expression Profiling; Humans; Insulin Resistance; Intra-Abdominal Fat; Liver; Mice; Mice, Inbred C57BL; Models, Molecular; PPAR alpha; PPAR gamma; Propionates; Stereoisomerism; Structure-Activity Relationship; Urea | 2012 |
Structural development studies of PPARs ligands based on tyrosine scaffold.
Topics: Dose-Response Relationship, Drug; Humans; Ligands; Molecular Docking Simulation; Molecular Structure; Peroxisome Proliferator-Activated Receptors; Structure-Activity Relationship; Tyrosine | 2015 |
New diphenylmethane derivatives as peroxisome proliferator-activated receptor alpha/gamma dual agonists endowed with anti-proliferative effects and mitochondrial activity.
Topics: Antineoplastic Agents; Benzhydryl Compounds; beta Catenin; Carnitine; Cell Proliferation; Drug Evaluation, Preclinical; Hep G2 Cells; HT29 Cells; Humans; Insulin Resistance; Mitochondria; Molecular Docking Simulation; PPAR alpha; PPAR gamma; Protein Conformation; Signal Transduction | 2017 |
Novel Phenyldiazenyl Fibrate Analogues as PPAR α/γ/δ Pan-Agonists for the Amelioration of Metabolic Syndrome.
Topics: | 2019 |
A chemoinformatics search for peroxisome proliferator-activated receptors ligands revealed a new pan-agonist able to reduce lipid accumulation and improve insulin sensitivity.
Topics: Cheminformatics; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Insulin Resistance; Ligands; Lipids; Peroxisome Proliferator-Activated Receptors; PPAR gamma | 2022 |
PPARalpha and PPARdelta activators inhibit cytokine-induced nuclear translocation of NF-kappaB and expression of VCAM-1 in EAhy926 endothelial cells.
Topics: Acetates; Active Transport, Cell Nucleus; Binding Sites; Cell Nucleus; Cells, Cultured; Chemokine CCL2; Cytokines; Down-Regulation; Endothelium, Vascular; Gene Expression; Humans; Intercellular Adhesion Molecule-1; Monocytes; NF-kappa B; Peroxisome Proliferators; Phenols; Phenoxyacetates; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Transcription Factors; Vascular Cell Adhesion Molecule-1 | 2002 |
Inactivation of peroxisome proliferator-activated receptor isoforms alpha, beta/delta, and gamma mediate distinct facets of hypertrophic transformation of adult cardiac myocytes.
Topics: Acyl-CoA Dehydrogenase; Animals; Atrial Natriuretic Factor; Cardiomegaly; Carnitine O-Palmitoyltransferase; CD36 Antigens; Cells, Cultured; Male; Myocytes, Cardiac; Oleic Acid; Palmitates; Phenoxyacetates; PPAR alpha; PPAR delta; PPAR gamma; PPAR-beta; Pyrimidines; Rats; RNA, Messenger; Thiazolidinediones | 2007 |
Norepinephrine and rosiglitazone synergistically induce Elovl3 expression in brown adipocytes.
Topics: Acetyltransferases; Adipocytes; Adipose Tissue, Brown; Animals; Cell Proliferation; Cycloheximide; Dactinomycin; Drug Synergism; Fatty Acid Elongases; Gene Expression Regulation; Male; Membrane Proteins; Mice; Norepinephrine; Peroxisome Proliferators; Phenoxyacetates; PPAR gamma; Protein Synthesis Inhibitors; Pyrimidines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Transcription, Genetic | 2007 |
Nuclear receptor agonists improve insulin responsiveness in cultured cardiomyocytes through enhanced signaling and preserved cytoskeletal architecture.
Topics: Alitretinoin; AMP-Activated Protein Kinase Kinases; Animals; Cells, Cultured; Cytoskeleton; Glucose; Glucose Transporter Type 4; Insulin; Insulin Resistance; Male; Microtubules; Myocytes, Cardiac; Phenoxyacetates; PPAR gamma; Protein Kinases; Pyrimidines; Rats; Rats, Sprague-Dawley; Retinoid X Receptors; Signal Transduction; Thiazolidinediones; Tretinoin | 2008 |
Peroxisome proliferator-activated receptor activators protect sebocytes from apoptosis: a new treatment modality for acne?
Topics: Acne Vulgaris; Apoptosis; Blotting, Western; Bromodeoxyuridine; Cell Line; Enzyme Inhibitors; Humans; L-Lactate Dehydrogenase; Peroxisome Proliferator-Activated Receptors; Phenoxyacetates; PPAR alpha; PPAR delta; PPAR gamma; Pyrimidines; Rosiglitazone; Sebaceous Glands; Staurosporine; Thiazolidinediones | 2011 |
In vitro effect of peroxisome proliferator activated receptor (PPAR) ligands on prostaglandin E2 synthesis and secretion by porcine endometrium during the estrous cycle and early pregnancy.
Topics: Animals; Dinoprostone; Endometrium; Estrous Cycle; Female; Indoles; Intramolecular Oxidoreductases; Ligands; Peroxisome Proliferator-Activated Receptors; Phenoxyacetates; Pregnancy; Prostaglandin-E Synthases; Pyrimidines; RNA, Messenger; Rosiglitazone; Swine; Thiazolidinediones | 2013 |
The involvement of peroxisome proliferator activated receptors (PPARs) in prostaglandin F2α production by porcine endometrium.
Topics: Analysis of Variance; Anilides; Animals; Benzamides; Culture Media; Dinoprost; DNA Primers; Endometrium; Estrous Cycle; Female; Indoles; Peroxisome Proliferator-Activated Receptors; Phenoxyacetates; Pregnancy; Prostaglandin D2; Pyridines; Pyrimidines; Radioimmunoassay; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Rosiglitazone; Swine; Thiazolidinediones | 2013 |
Peroxisome proliferator activated receptor ligands affect progesterone and 17β-estradiol secretion by porcine corpus luteum during early pregnancy.
Topics: 3-Hydroxysteroid Dehydrogenases; Anilides; Animals; Benzamides; Corpus Luteum; Estradiol; Estrous Cycle; Female; Gene Expression; Indoles; Ligands; Peroxisome Proliferator-Activated Receptors; Phenoxyacetates; Pregnancy; Progesterone; Prostaglandin D2; Pyridines; Pyrimidines; RNA, Messenger; Rosiglitazone; Swine; Thiazolidinediones | 2014 |