pirinixic acid has been researched along with gw 7647 in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (43.75) | 29.6817 |
| 2010's | 7 (43.75) | 24.3611 |
| 2020's | 2 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Paulke, A; Proschak, E; Schneider, G; Schubert-Zsilavecz, M; Steri, R; Thieme, TM | 1 |
| Capelli, D; Di Giovanni, C; Faliti, S; Fracchiolla, G; Iacobazzi, V; Infantino, V; Laghezza, A; Lavecchia, A; Loiodice, F; Montanari, R; Piemontese, L; Pochetti, G; Tortorella, P | 1 |
| Dittrich, M; Lamers, C; Proschak, E; Schubert-Zsilavecz, M; Steri, R | 1 |
| Ahowesso, C; Black, PN; DiRusso, CC; Montefusco, D; Saini, N | 1 |
| Ammazzalorso, A; Amoroso, R; Brunetti, L; Bruno, I; Cama, A; Capone, F; Cerchia, C; De Filippis, B; Fantacuzzi, M; Ferrante, C; Florio, R; Giampietro, L; Laghezza, A; Lavecchia, A; Loiodice, F; Maccallini, C; Recinella, L; Tortorella, P; Verginelli, F | 1 |
| Ahn, S; An, S; Gong, J; Hwang, SY; Jung, D; Kim, H; Kim, HP; Kim, J; Lee, J; Noh, M; Pyo, JJ; Shin, I | 1 |
| Arnesen, H; Haj-Yasein, NN; Hansen, TV; Matthews, J; Nebb, HI; Paulsen, SM; Soedling, H; Sylte, I; Sæther, T; Tungen, JE | 1 |
| Ammazzalorso, A; Amoroso, R; Bruno, I; Cama, A; Cerchia, C; De Filippis, B; De Lellis, L; Fantacuzzi, M; Florio, R; Giampietro, L; Laghezza, A; Lavecchia, A; Loiodice, F; Maccallini, C; Tortorella, P; Veschi, S | 1 |
| Alves, PS; Bhattacharyya, M; Brand, GD; Cummins, CL; Ferreira, TAM; Grouleff, J; Krause, H; Leite, JRSA; Liu, J; Magomedova, L; Moreira, DC; Nogueira, PCN; Oliveira, AS; Poda, G; Queiroz, FJG; Romeiro, LAS; Sahin, C; Silveira, ER; Tiefenbach, J; Uehling, D | 1 |
| Fu, J; Gaetani, S; Lin, E; Oveisi, F; Piomelli, D | 1 |
| Bento-Abreu, A; Medina, JM; Tabernero, A | 1 |
| Babaev, VR; Ding, L; Dove, DE; Fazio, S; Ishiguro, H; Kovacs, WJ; Linton, MF; Semenkovich, CF; Yancey, PG | 1 |
| Kankaanranta, H; Leppänen, T; Moilanen, E; Paukkeri, EL; Sareila, O; Vuolteenaho, K | 1 |
| Hannig, M; Piper, HM; Sauer, H; Sharifpanah, F; Wartenberg, M | 1 |
| Bermúdez-Silva, FJ; de Fonseca, FR; Fuentes, E; Juan-Picó, P; Nadal, A; Quesada, I; Rafacho, A; Roche, E; Ropero, AB | 1 |
| Dullens, SP; Mariman, EC; Mensink, RP; Plat, J | 1 |
16 other study(ies) available for pirinixic acid and gw 7647
| Article | Year |
|---|---|
Rational design of a pirinixic acid derivative that acts as subtype-selective PPARgamma modulator.
Topics: Drug Design; Models, Molecular; PPAR gamma; Pyrimidines | 2010 |
New 2-(aryloxy)-3-phenylpropanoic acids as peroxisome proliferator-activated receptor α/γ dual agonists able to upregulate mitochondrial carnitine shuttle system gene expression.
Topics: Calorimetry; Carnitine O-Palmitoyltransferase; Cell Line, Tumor; Crystallography, X-Ray; Humans; Membrane Transport Proteins; Mitochondrial Proteins; Molecular Docking Simulation; PPAR alpha; PPAR gamma; Propionates; Protein Conformation; Stereoisomerism; Structure-Activity Relationship; Thermodynamics; Transcriptional Activation; Up-Regulation | 2013 |
Molecular determinants for improved activity at PPARα: structure-activity relationship of pirinixic acid derivatives, docking study and site-directed mutagenesis of PPARα.
Topics: Dose-Response Relationship, Drug; Humans; Hydrogen Bonding; Molecular Docking Simulation; Molecular Structure; Mutagenesis, Site-Directed; PPAR alpha; Pyrimidines; Structure-Activity Relationship | 2014 |
Fatty Acid Transport Proteins: Targeting FATP2 as a Gatekeeper Involved in the Transport of Exogenous Fatty Acids.
Topics: | 2016 |
Novel Phenyldiazenyl Fibrate Analogues as PPAR α/γ/δ Pan-Agonists for the Amelioration of Metabolic Syndrome.
Topics: | 2019 |
2-Phenyl-8-(1-phenylallyl)-chromenone compounds have a pan-PPAR modulator pharmacophore.
Topics: Adiponectin; Humans; Models, Molecular; PPAR gamma | 2019 |
Molecular modelling, synthesis, and biological evaluations of a 3,5-disubstituted isoxazole fatty acid analogue as a PPARα-selective agonist.
Topics: Fatty Acids; Humans; Isoxazoles; Models, Molecular; PPAR alpha | 2019 |
Sulfonimide and Amide Derivatives as Novel PPARα Antagonists: Synthesis, Antiproliferative Activity, and Docking Studies.
Topics: | 2020 |
Phenolic Lipids Derived from Cashew Nut Shell Liquid to Treat Metabolic Diseases.
Topics: 3T3-L1 Cells; Anacardic Acids; Anacardium; Animals; Drug Design; Gene Expression; HEK293 Cells; Humans; Lipid Metabolism; Male; Mice; Mice, Inbred C57BL; Molecular Docking Simulation; Nuts; PPAR alpha; PPAR delta; PPAR gamma; Protein Domains; Zebrafish | 2022 |
Oleoylethanolamide, an endogenous PPAR-alpha agonist, lowers body weight and hyperlipidemia in obese rats.
Topics: Animals; Body Weight; Butyrates; CD36 Antigens; Cholesterol; Coenzyme A Ligases; Eating; Endocannabinoids; Fatty Acid-Binding Proteins; Hepatocytes; Hyperlipidemias; Ion Channels; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondrial Proteins; Obesity; Oleic Acids; Phenylurea Compounds; PPAR alpha; Pyrimidines; Rats; Rats, Inbred WF; Rats, Zucker; RNA, Messenger; Thiazoles; Thiazolidinediones; Triglycerides; Uncoupling Protein 2 | 2005 |
Peroxisome proliferator-activated receptor-alpha is required for the neurotrophic effect of oleic acid in neurons.
Topics: Animals; Butyrates; Cell Differentiation; Cell Shape; Cells, Cultured; Central Nervous System; GAP-43 Protein; Growth Cones; Microtubule-Associated Proteins; Nerve Growth Factors; Neurites; Neurons; Oleic Acid; Phenylurea Compounds; PPAR alpha; Pyrimidines; Rats; Rats, Wistar; RNA, Small Interfering | 2007 |
Macrophage expression of peroxisome proliferator-activated receptor-alpha reduces atherosclerosis in low-density lipoprotein receptor-deficient mice.
Topics: Animals; Aortic Diseases; Atherosclerosis; Biological Transport; Bone Marrow Transplantation; Butyrates; Cells, Cultured; Female; Gene Expression Regulation; Inflammation; Lipid Metabolism; Lipoproteins, LDL; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phenylurea Compounds; PPAR alpha; Pyrimidines; Radiation Chimera; Receptors, LDL | 2007 |
PPARalpha agonists inhibit nitric oxide production by enhancing iNOS degradation in LPS-treated macrophages.
Topics: Acetylcysteine; Animals; Butyrates; Cells, Cultured; Dose-Response Relationship, Drug; Leupeptins; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Phenylurea Compounds; PPAR alpha; Proteasome Endopeptidase Complex; Pyrimidines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; STAT1 Transcription Factor | 2007 |
Peroxisome proliferator-activated receptor alpha agonists enhance cardiomyogenesis of mouse ES cells by utilization of a reactive oxygen species-dependent mechanism.
Topics: Animals; Butyrates; Cell Differentiation; Cells, Cultured; Clofibric Acid; Embryonic Stem Cells; Enzyme Inhibitors; Fibric Acids; Free Radical Scavengers; Gene Expression; Gene Expression Regulation, Developmental; Heart; Immunohistochemistry; Indoles; Mice; Myocytes, Cardiac; NADPH Oxidases; Peroxisome Proliferators; Phenylurea Compounds; PPAR alpha; PPAR gamma; PPAR-beta; Pyrimidines; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2008 |
Rapid non-genomic regulation of Ca2+ signals and insulin secretion by PPAR alpha ligands in mouse pancreatic islets of Langerhans.
Topics: Animals; Anticholesteremic Agents; Butyrates; Calcium; Insulin; Insulin Secretion; Insulin-Secreting Cells; Male; Mediator Complex Subunit 1; Mice; Mitochondria; Oleic Acids; Phenylurea Compounds; Pyrimidines; Reactive Oxygen Species; Transcription Factors | 2009 |
Differentiated CaCo-2 cells as an in-vitro model to evaluate de-novo apolipoprotein A-I production in the small intestine.
Topics: Anticholesteremic Agents; Apolipoprotein A-I; Butyrates; Caco-2 Cells; Cell Differentiation; Drug Evaluation, Preclinical; Hep G2 Cells; Humans; Intestine, Small; Isoxazoles; Models, Biological; Peroxisome Proliferators; Phenylurea Compounds; Pyrimidines; Receptors, Cytoplasmic and Nuclear | 2009 |