pirinixic acid has been researched along with gw 501516 in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (60.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Giri, S; Goel, A; Jain, M; Makadia, P; Patel, H; Patel, M; Patel, P; Pingali, H; Shah, S; Zaware, P | 1 |
| Basu, S; Giri, S; Godha, A; Goel, A; Goswami, A; Jain, M; Makadia, P; Patel, H; Patel, M; Patel, P; Patil, P; Pingali, H; Shah, S; Zaware, P | 1 |
| Bahekar, R; Giri, S; Jain, M; Makadia, P; Patel, D; Patel, P; Pingali, H; Pola, S; Priyadarshini, P; Shah, M; Shah, SR; Suthar, D; Thube, B; Trivedi, C; Zaware, P | 1 |
| Choi, P; Ham, J; Jeong, KH; Kim, SN; Kim, T; Lee, S; Lee, W; Park, SH; Song, JH | 1 |
| Ahn, S; An, S; Gong, J; Hwang, SY; Jung, D; Kim, H; Kim, HP; Kim, J; Lee, J; Noh, M; Pyo, JJ; Shin, I | 1 |
| Fu, J; Gaetani, S; Lin, E; Oveisi, F; Piomelli, D | 1 |
| Johnson, TE; Shi, S; Umbenhauer, DR; Zhang, X | 1 |
| De Windt, LJ; Smeets, PJ; Teunissen, BE; Van Bilsen, M; Van der Vusse, GJ; Willemsen, PH | 1 |
| Gosker, HR; Langen, RC; Remels, AH; Russell, AP; Schols, AM; Schrauwen, P; Spaapen, F; Voncken, JW | 1 |
| Bérubé-Simard, FA; Bousette, N; Haffar, T | 1 |
10 other study(ies) available for pirinixic acid and gw 501516
| Article | Year |
|---|---|
Design and synthesis of novel oxazole containing 1,3-dioxane-2-carboxylic acid derivatives as PPAR alpha/gamma dual agonists.
Topics: Animals; Carboxylic Acids; Diabetes Mellitus; Drug Design; Hypoglycemic Agents; Mice; Mice, Inbred NOD; Molecular Structure; Oxazoles; PPAR alpha; PPAR gamma; Rats; Rats, Zucker; Structure-Activity Relationship | 2008 |
Discovery of a highly orally bioavailable c-5-[6-(4-Methanesulfonyloxyphenyl)hexyl]-2-methyl-1,3-dioxane-r-2-carboxylic acid as a potent hypoglycemic and hypolipidemic agent.
Topics: Animals; Carboxylic Acids; Diabetes Mellitus, Type 2; Dioxanes; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Lipids; Mesylates; Mice; Models, Chemical; Peroxisome Proliferator-Activated Receptors; PPAR alpha; PPAR gamma; Rats; Rats, Wistar; Transcriptional Activation | 2008 |
Effect of structurally constrained oxime-ether linker on PPAR subtype selectivity: Discovery of a novel and potent series of PPAR-pan agonists.
Topics: Animals; Cricetinae; Disease Models, Animal; Ether; Hep G2 Cells; Humans; Hypoglycemic Agents; Male; Mice; Mice, Obese; Oximes; Peroxisome Proliferator-Activated Receptors; PPAR alpha; PPAR delta; PPAR gamma; Structure-Activity Relationship; Thiazoles | 2011 |
Total synthesis and dual PPARα/γ agonist effects of amorphastilbol and its synthetic derivatives.
Topics: Adipocytes; Animals; Borates; Cannabinoids; Cell Differentiation; Cell Line; Humans; Hypoglycemic Agents; Lipid Metabolism; Mice; Plant Extracts; PPAR alpha; PPAR gamma; Robinia; Seeds; Stilbenes | 2012 |
2-Phenyl-8-(1-phenylallyl)-chromenone compounds have a pan-PPAR modulator pharmacophore.
Topics: Adiponectin; Humans; Models, Molecular; PPAR gamma | 2019 |
Oleoylethanolamide, an endogenous PPAR-alpha agonist, lowers body weight and hyperlipidemia in obese rats.
Topics: Animals; Body Weight; Butyrates; CD36 Antigens; Cholesterol; Coenzyme A Ligases; Eating; Endocannabinoids; Fatty Acid-Binding Proteins; Hepatocytes; Hyperlipidemias; Ion Channels; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondrial Proteins; Obesity; Oleic Acids; Phenylurea Compounds; PPAR alpha; Pyrimidines; Rats; Rats, Inbred WF; Rats, Zucker; RNA, Messenger; Thiazoles; Thiazolidinediones; Triglycerides; Uncoupling Protein 2 | 2005 |
Statins and PPARalpha agonists induce myotoxicity in differentiated rat skeletal muscle cultures but do not exhibit synergy with co-treatment.
Topics: Adenosine Triphosphate; Animals; Cell Death; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Induction; Fibrinolytic Agents; Gene Expression; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ion Channels; Membrane Transport Proteins; Mitochondrial Proteins; Muscle Fibers, Skeletal; Muscular Diseases; Myoblasts, Skeletal; Peroxisome Proliferator-Activated Receptors; Pyrimidines; Rats; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Time Factors; Uncoupling Protein 2 | 2005 |
Activation of PPARdelta inhibits cardiac fibroblast proliferation and the transdifferentiation into myofibroblasts.
Topics: Animals; Animals, Newborn; Cell Differentiation; Cell Proliferation; Cells, Cultured; Collagen; Fibroblasts; Fibrosis; Humans; Immunohistochemistry; Ligands; Myocytes, Cardiac; Peroxisome Proliferators; PPAR alpha; PPAR delta; PPAR gamma; Pyrimidines; Rats; Rats, Inbred Lew; Rosiglitazone; Thiazoles; Thiazolidinediones; Transduction, Genetic | 2007 |
PPARgamma inhibits NF-kappaB-dependent transcriptional activation in skeletal muscle.
Topics: Animals; Cells, Cultured; Cytokines; Down-Regulation; Humans; Hypoglycemic Agents; Inflammation Mediators; Male; Mice; Middle Aged; Muscle, Skeletal; NF-kappa B; PPAR gamma; Pyrimidines; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcriptional Activation | 2009 |
Cardiomyocyte lipotoxicity is mediated by Il-6 and causes down-regulation of PPARs.
Topics: Acetylcarnitine; Animals; Animals, Newborn; Carnitine O-Palmitoyltransferase; Cell Death; Cells, Cultured; Cytokines; Down-Regulation; Gene Expression Regulation; Interleukin-6; Myocytes, Cardiac; Oleic Acid; Palmitates; PPAR alpha; PPAR delta; Pyrimidines; Rats, Sprague-Dawley; Thiazoles | 2015 |