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pirinixic acid and diethylhexyl phthalate

pirinixic acid has been researched along with diethylhexyl phthalate in 42 studies

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-19907 (16.67)18.7374
1990's25 (59.52)18.2507
2000's8 (19.05)29.6817
2010's2 (4.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Imanaka, T; Itoga, H; Okawa, S; Suga, T; Watanabe, T1
Gemmell, MA; Giometti, CS; Lalwani, ND; Reddy, JK; Taylor, J; Tollaksen, SL2
Crane, DI; Masters, CJ; Zamattia, J1
Bartles, JR; Fayos, BE; Isoye, ST; Khuon, S; Lin, XH; Nehme, CL; Rao, MS; Reddy, JK; Zhang, LQ1
Cattley, RC; Conway, JG; Marsman, DS; Olson, MJ; Popp, JA; Tomaszewski, KE1
Chen, N; Crane, DI; Masters, C1
Cattley, RC; Conway, JG; Marsman, DS; Popp, JA1
Butterworth, BE; Cattley, RC; Popp, JA; Smith-Oliver, T1
Butterworth, BE; Cattley, RC; Popp, JA; Richardson, KK; Smith-Oliver, T1
Lalwani, ND; Reddy, JK; Watanabe, T1
Earley, K; Goel, SK; Gupta, RC; Reddy, JK; Singh, B1
Hayashi, F; Suga, T; Tamura, H; Watanabe, T1
Byers, DM; Cook, HW; Palmer, FB; Thorne, PC1
Hayashi, F; Kasai, H; Suga, T; Tamura, H; Yamada, J1
Aldridge, TC; Green, S; Issemann, I; Prince, RA; Tugwood, JD1
Greim, H; Leibold, E; Schwarz, LR1
Alvares, K; Capone, JP; Dadras, SS; Fan, C; Iannaccone, PM; Rachubinski, RA; Rao, MS; Reddy, JK; Subramani, S; Yeldandi, AV1
Cattley, RC; Glover, SE1
Bartles, JR; Fayos, BE1
Galloway, SM; Joslyn, DJ; Ledwith, BJ; Manam, S; Nichols, WW; Troilo, P1
Barrett, JC; Tsutsui, T; Watanabe, E1
Anderson, NL; Eacho, P; Esquer-Blasco, R; Foxworthy, P; Richardson, F1
Alberts, DW; Ledwith, BJ; Manam, S; Pauley, CJ; Rokos, CL; Wagner, LK1
Gonzalez, FJ; Motojima, K; Peters, JM1
Esumi, H; Hayashi, F; Motoki, Y; Ogura, T; Suga, T; Tamura, H; Watanabe, T1
Gonzalez, FJ; Latruffe, N; Motojima, K; Passilly, P; Peters, JM1
de la Iglesia, FA; Dethloff, LA1
Bradford, BU; Cattley, RC; Graves, LM; Rivera, CA; Rose, ML; Schoonhoven, R; Swenberg, JA; Thurman, RG1
Wallace, KB; Zhou, S1
Anderson, SP; Cattley, RC; Corton, JC1
Armstrong, MJ; Ashby, J; Galloway, SM; Johnson, TE1
Adinehzadeh, M; Reo, NV1
Brown, WJ; de Figueiredo, P1
Depierre, JW; Xie, Y; Yang, Q1
Davis, BJ; Lovekamp, TN1
Hamano, T; Hayashi, M; Kobayashi, K; Mutai, M; Sakairi, T1
Bradford, BU; Burns, AM; Connor, HD; Cunningham, ML; Kadiiska, MB; Maki, A; Mason, RP; Peters, JM; Rusyn, I; Woods, CG1
Bagnyukova, TV; Boureiko, A; Melnyk, S; Montgomery, B; Pogribny, IP; Rusyn, I; Tryndyak, VP1
Brown, RP; Gillum, N; Karabekian, Z; Kay, MW; Sarvazyan, N; Swift, LM1
Cho, WS; Choi, M; Han, BS; Jeong, J; Park, SN; Son, WC1
Ding, H; Idrees, R; Jaimes, R; Karabekian, Z; Laflamme, MA; Posnack, NG; Sarvazyan, N; Stybayeva, G1

Reviews

1 review(s) available for pirinixic acid and diethylhexyl phthalate

ArticleYear
Delineating peroxisome proliferator action to improve human risk assessment.
    Progress in clinical and biological research, 1994, Volume: 387

    Topics: Acyl-CoA Oxidase; Animals; Base Sequence; Clofibrate; Cloning, Molecular; Diethylhexyl Phthalate; DNA; Fatty Acids; Humans; Liver; Liver Neoplasms, Experimental; Mice; Microbodies; Molecular Sequence Data; Oxidoreductases; Promoter Regions, Genetic; Pyrimidines; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Risk Assessment; Transcription Factors; Tretinoin

1994

Other Studies

41 other study(ies) available for pirinixic acid and diethylhexyl phthalate

ArticleYear
Involvement of calmodulin- and protein kinase C-related mechanism in an induction process of peroxisomal fatty acid oxidation-related enzymes by hypolipidemic peroxisome proliferators.
    Biochimica et biophysica acta, 1992, Apr-30, Volume: 1135, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Bezafibrate; Body Weight; Calmodulin; Catalase; Cells, Cultured; Clofibrate; Diethylhexyl Phthalate; Electrophoresis, Polyacrylamide Gel; Isoquinolines; Kinetics; Liver; Male; Membrane Proteins; Microbodies; Molecular Weight; Organ Size; Oxidation-Reduction; Piperazines; Protein Kinase C; Pyrimidines; Rats; Rats, Inbred Strains; Reference Values; Trifluoperazine

1992
A comparative study of the effects of clofibrate, ciprofibrate, WY-14,643, and di-(2-ethylhexyl)-phthalate on liver protein expression in mice.
    Applied and theoretical electrophoresis : the official journal of the International Electrophoresis Society, 1991, Volume: 2, Issue:4-5

    Topics: Animals; Clofibric Acid; Diethylhexyl Phthalate; Electrophoresis, Gel, Two-Dimensional; Female; Fibric Acids; Hypolipidemic Agents; Liver; Male; Membrane Proteins; Mice; Microbodies; Pyrimidines

1991
Quantitative changes in sets of proteins as markers of biological response.
    Progress in clinical and biological research, 1991, Volume: 372

    Topics: Animals; Biomarkers; Carcinogens; Clofibrate; Clofibric Acid; Diethylhexyl Phthalate; Electrophoresis, Gel, Two-Dimensional; Fibric Acids; Liver; Liver Neoplasms, Experimental; Male; Mice; Proteins; Pyrimidines

1991
Alterations in the integrity of peroxisomal membranes in livers of mice treated with peroxisome proliferators.
    Molecular and cellular biochemistry, 1990, Aug-10, Volume: 96, Issue:2

    Topics: Animals; Catalase; Clofibrate; Diethylhexyl Phthalate; Female; Mice; Microbodies; Mitochondria, Liver; Pyrimidines; Sonication

1990
Peroxisome proliferator-induced alterations in the expression and modification of rat hepatocyte plasma membrane proteins.
    Cancer research, 1990, Feb-01, Volume: 50, Issue:3

    Topics: Antibodies, Monoclonal; Asialoglycoprotein Receptor; Blotting, Western; Clofibrate; Clofibric Acid; Diethylhexyl Phthalate; ErbB Receptors; Fibric Acids; Fluorescent Antibody Technique; Isoelectric Point; Liver; Membrane Glycoproteins; Microbodies; Pyrimidines; Receptors, Immunologic; Sialoglycoproteins

1990
Relationship of oxidative damage to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and Wy-14,643.
    Carcinogenesis, 1989, Volume: 10, Issue:3

    Topics: Animals; Anticholesteremic Agents; Cell Division; Diethylhexyl Phthalate; Enzyme Induction; Hydrogen Peroxide; Lipofuscin; Liver Neoplasms, Experimental; Lysosomes; Male; Microbodies; Oxidation-Reduction; Phthalic Acids; Pyrimidines; Rats; Rats, Inbred F344; Vitamin E

1989
Changes to the integral membrane protein composition of mouse liver peroxisomes in response to the peroxisome proliferators clofibrate, Wy-14,643 and di(2-ethyl-hexyl)phthalate.
    Molecular and cellular biochemistry, 1988, Volume: 81, Issue:1

    Topics: Animals; Antineoplastic Agents; Catalase; Clofibrate; Diethylhexyl Phthalate; Liver; Membrane Proteins; Mice; Microbodies; Oxidation-Reduction; Phthalic Acids; Pyrimidines

1988
Relationship of hepatic peroxisome proliferation and replicative DNA synthesis to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid (Wy-14,643) in rats.
    Cancer research, 1988, Dec-01, Volume: 48, Issue:23

    Topics: Animals; Body Weight; Cell Division; Diethylhexyl Phthalate; DNA; DNA Replication; Eating; Liver; Liver Neoplasms, Experimental; Male; Microbodies; Phthalic Acids; Pyrimidines; Rats; Rats, Inbred F344

1988
Failure of the peroxisome proliferator WY-14,643 to induce unscheduled DNA synthesis in rat hepatocytes following in vivo treatment.
    Carcinogenesis, 1988, Volume: 9, Issue:7

    Topics: 2-Acetylaminofluorene; Animals; Carnitine O-Acetyltransferase; Diethylhexyl Phthalate; DNA; DNA Repair; Hydrogen Peroxide; In Vitro Techniques; Liver; Microbodies; Oxidoreductases; Pyrimidines; Rats

1988
Effect of peroxisome proliferator carcinogens on unscheduled DNA synthesis in rat hepatocytes determined by autoradiography.
    Cancer letters, 1986, Volume: 33, Issue:3

    Topics: Animals; Autoradiography; Carcinogens; Cell Division; Diethylhexyl Phthalate; DNA Repair; In Vitro Techniques; Liver; Male; Microbodies; Nafenopin; Pyrimidines; Rats; Rats, Inbred F344

1986
Specific changes in the protein composition of rat liver in response to the peroxisome proliferators ciprofibrate, Wy-14,643 and di-(2-ethylhexyl)phthalate.
    The Biochemical journal, 1985, May-01, Volume: 227, Issue:3

    Topics: Animals; Centrifugation, Density Gradient; Diethylhexyl Phthalate; Electrophoresis, Polyacrylamide Gel; In Vitro Techniques; Liver; Male; Microbodies; Microscopy, Electron; Phthalic Acids; Proteins; Pyrimidines; Rats; Rats, Inbred F344

1985
32P-postlabeling analysis of peroxisome proliferator-DNA adduct formation in rat liver in vivo and hepatocytes in vitro.
    Carcinogenesis, 1985, Volume: 6, Issue:6

    Topics: Animals; Anticholesteremic Agents; Carcinogens; Clofibrate; Clofibric Acid; Diethylhexyl Phthalate; DNA; Fibric Acids; Hypolipidemic Agents; In Vitro Techniques; Liver; Liver Neoplasms; Male; Microbodies; Phosphorus Radioisotopes; Pyrimidines; Rats

1985
Enhancement by peroxisome proliferators of the susceptibility to DNA damage in the liver of male F344 rats.
    Cancer letters, 1995, May-25, Volume: 92, Issue:1

    Topics: Animals; Carcinogens; Diethylhexyl Phthalate; Dimethylnitrosamine; DNA Damage; Liver; Male; Methyl Methanesulfonate; Microbodies; Pyrimidines; Rats; Rats, Inbred F344

1995
Clofibrate and other peroxisomal proliferating agents relatively specifically inhibit synthesis of ethanolamine phosphoglycerides in cultured human fibroblasts.
    Biochimica et biophysica acta, 1994, Sep-15, Volume: 1214, Issue:2

    Topics: Cells, Cultured; Choline; Clofibrate; Diethylhexyl Phthalate; Ethanolamine; Ethanolamines; Fatty Alcohols; Humans; Linolenic Acids; Microbodies; Phosphatidylethanolamines; Plasmalogens; Pyrimidines

1994
Characteristics of the hepatocarcinogenesis caused by dehydroepiandrosterone, a peroxisome proliferator, in male F-344 rats.
    Carcinogenesis, 1994, Volume: 15, Issue:10

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Carcinogens; Dehydroepiandrosterone; Deoxyguanosine; Diethylhexyl Phthalate; Glutathione; Glutathione Peroxidase; Lipid Peroxides; Liver; Liver Neoplasms, Experimental; Male; Microbodies; Pyrimidines; Rats; Rats, Inbred F344

1994
Inhibition of intercellular communication of rat hepatocytes by nafenopin: involvement of protein kinase C.
    Carcinogenesis, 1994, Volume: 15, Issue:6

    Topics: Animals; Cell Communication; Diethylhexyl Phthalate; Isoenzymes; Liver; Male; Nafenopin; Protein Kinase C; Pyrimidines; Rats; Rats, Wistar

1994
An upstream region of the enoyl-coenzyme A hydratase/3-hydroxyacyl-coenzyme A dehydrogenase gene directs luciferase expression in liver in response to peroxisome proliferators in transgenic mice.
    Cancer research, 1994, May-01, Volume: 54, Issue:9

    Topics: 3-Hydroxyacyl CoA Dehydrogenases; Animals; Clofibric Acid; Diethylhexyl Phthalate; Enoyl-CoA Hydratase; Fibric Acids; Genes, Reporter; Liver; Luciferases; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Transgenic; Microbodies; Nafenopin; Pyrimidines

1994
Elevated 8-hydroxydeoxyguanosine in hepatic DNA of rats following exposure to peroxisome proliferators: relationship to carcinogenesis and nuclear localization.
    Carcinogenesis, 1993, Volume: 14, Issue:12

    Topics: Animals; Body Weight; Carcinogens; Cell Nucleus; Clofibric Acid; Diethylhexyl Phthalate; DNA; Guanosine; Liver; Male; Microbodies; Organ Size; Phenobarbital; Pyrimidines; Rats; Rats, Inbred F344

1993
Regulation of hepatocytic glycoprotein sialylation and sialyltransferases by peroxisome proliferators.
    The Journal of biological chemistry, 1994, Jan-21, Volume: 269, Issue:3

    Topics: Animals; Anticholesteremic Agents; beta-D-Galactoside alpha 2-6-Sialyltransferase; beta-Galactosidase; beta-Galactoside alpha-2,3-Sialyltransferase; Blotting, Western; Clofibric Acid; Diethylhexyl Phthalate; Electrophoresis, Polyacrylamide Gel; Fibric Acids; Glycoproteins; Hypolipidemic Agents; Kinetics; Liver; Male; Membrane Glycoproteins; Microbodies; Molecular Weight; Pyrimidines; Rats; Rats, Inbred F344; RNA, Messenger; Sialoglycoproteins; Sialyltransferases

1994
Activation of immediate-early gene expression by peroxisome proliferators in vitro.
    Molecular carcinogenesis, 1993, Volume: 8, Issue:1

    Topics: 3T3 Cells; Animals; Carcinogens; Diethylhexyl Phthalate; DNA Damage; Gene Expression Regulation; Genes, fos; Genes, jun; Liver; Liver Neoplasms, Experimental; Mice; Microbodies; Protein Kinase C; Pyrimidines; Signal Transduction; Stimulation, Chemical

1993
Ability of peroxisome proliferators to induce cell transformation, chromosome aberrations and peroxisome proliferation in cultured Syrian hamster embryo cells.
    Carcinogenesis, 1993, Volume: 14, Issue:4

    Topics: Animals; Benzidines; Cell Transformation, Neoplastic; Chromosome Aberrations; Clofibrate; Cricetinae; Diethylhexyl Phthalate; Mesocricetus; Microbodies; Pyrimidines

1993
The effects of peroxisome proliferators on protein abundances in mouse liver.
    Toxicology and applied pharmacology, 1996, Volume: 137, Issue:1

    Topics: Acetophenones; Amino Acid Sequence; Animals; Anticholesteremic Agents; Clofibric Acid; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Electrophoresis, Gel, Two-Dimensional; Image Processing, Computer-Assisted; Liver; Male; Mice; Microbodies; Molecular Sequence Data; Nafenopin; Oxidation-Reduction; Proteins; Pyrimidines; Rats; Tetrazoles

1996
Induction of cyclooxygenase-2 expression by peroxisome proliferators and non-tetradecanoylphorbol 12,13-myristate-type tumor promoters in immortalized mouse liver cells.
    The Journal of biological chemistry, 1997, Feb-07, Volume: 272, Issue:6

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Carcinogens; Cyclooxygenase 1; Cyclooxygenase 2; Diethylhexyl Phthalate; Dinoprostone; Enzyme Induction; Indomethacin; Isoenzymes; Liver; Membrane Proteins; Mice; Prostaglandin-Endoperoxide Synthases; Pyrimidines; RNA, Messenger; Tetradecanoylphorbol Acetate

1997
PPAR alpha mediates peroxisome proliferator-induced transcriptional repression of nonperoxisomal gene expression in mouse.
    Biochemical and biophysical research communications, 1997, Jan-03, Volume: 230, Issue:1

    Topics: Alpha-Globulins; Animals; Clofibrate; Diethylhexyl Phthalate; Gene Expression Regulation; Kinetics; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Inbred DBA; Mice, Inbred Strains; Mice, Knockout; Microbodies; Nuclear Proteins; Prealbumin; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Species Specificity; Time Factors; Transcription Factors; Transcription, Genetic

1997
Induction of hepatic poly(ADP-ribose) polymerase by peroxisome proliferators, non-genotoxic hepatocarcinogens.
    Cancer letters, 1998, May-15, Volume: 127, Issue:1-2

    Topics: Administration, Oral; Animals; Carcinogens; Diethylhexyl Phthalate; Enzyme Induction; Liver; Liver Neoplasms; Male; Poly(ADP-ribose) Polymerases; Pyrimidines; Rats; Rats, Inbred F344; RNA, Messenger

1998
Expression of putative fatty acid transporter genes are regulated by peroxisome proliferator-activated receptor alpha and gamma activators in a tissue- and inducer-specific manner.
    The Journal of biological chemistry, 1998, Jul-03, Volume: 273, Issue:27

    Topics: Adipates; Adipose Tissue; Animals; Base Sequence; CD36 Antigens; Clofibrate; Diethylhexyl Phthalate; DNA Primers; Gene Expression Regulation; Liver; Liver Neoplasms, Experimental; Male; Membrane Glycoproteins; Mice; Microbodies; Organic Anion Transporters; Pyrimidines; Rats; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Transcription Factors; Tumor Cells, Cultured

1998
Chemical-induced hepatocyte ploidy.
    Toxicology and applied pharmacology, 1998, Volume: 150, Issue:2

    Topics: Animals; Carcinogens; Cell Cycle; Diethylhexyl Phthalate; DNA; Liver; Polyploidy; Pyrimidines

1998
Kupffer cell oxidant production is central to the mechanism of peroxisome proliferators.
    Carcinogenesis, 1999, Volume: 20, Issue:1

    Topics: Animals; Calcium Signaling; Cell Division; Cell Transformation, Neoplastic; Diet; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Endotoxins; Enzyme Activation; Enzyme Inhibitors; Glycine; Intestines; Kupffer Cells; Liver Neoplasms, Experimental; Male; Oxidants; Oxidative Stress; Peroxisome Proliferators; Protein Kinase C; Pyrimidines; Rats; Rats, Sprague-Dawley; Staurosporine; Superoxides

1999
The effect of peroxisome proliferators on mitochondrial bioenergetics.
    Toxicological sciences : an official journal of the Society of Toxicology, 1999, Volume: 48, Issue:1

    Topics: Animals; Bezafibrate; Calcium; Clofibrate; Clofibric Acid; Diethylhexyl Phthalate; Energy Metabolism; Fenofibrate; Fibric Acids; Gemfibrozil; Intracellular Membranes; Male; Membrane Potentials; Mitochondria, Liver; Mitochondrial Swelling; Oxygen; Permeability; Peroxisome Proliferators; Pyrimidines; Rats; Rats, Sprague-Dawley; Trichloroethylene

1999
Hepatic expression of acute-phase protein genes during carcinogenesis induced by peroxisome proliferators.
    Molecular carcinogenesis, 1999, Volume: 26, Issue:4

    Topics: Adenoma; Animals; Diethylhexyl Phthalate; Diethylnitrosamine; Gene Expression Regulation, Neoplastic; Liver; Liver Neoplasms; Male; Mice; Mice, Knockout; Microbodies; Orosomucoid; Peroxisome Proliferators; Pyrimidines; Rats; Rats, Inbred F344; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Transcription, Genetic

1999
The genetic toxicity of the peroxisome proliferator class of rodent hepatocarcinogen.
    Mutation research, 2000, Mar-17, Volume: 448, Issue:2

    Topics: Animals; CHO Cells; Clofenapate; Cricetinae; Diethylhexyl Phthalate; Humans; Molecular Structure; Nafenopin; Peroxisome Proliferators; Pyrimidines

2000
NMR spectroscopic analyses of liver phosphatidylcholine and phosphatidylethanolamine biosynthesis in rats exposed to peroxisome proliferators-A class of nongenotoxic hepatocarcinogens.
    Toxicology and applied pharmacology, 2000, Apr-15, Volume: 164, Issue:2

    Topics: Analysis of Variance; Animals; Caprylates; Carcinogens; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Fluorocarbons; Injections, Intraperitoneal; Liver; Magnetic Resonance Spectroscopy; Male; Peroxisome Proliferators; Phosphatidylcholines; Phosphatidylethanolamines; Pyrimidines; Rats; Rats, Inbred F344

2000
Clofibrate inhibits membrane trafficking to the Golgi complex and induces its retrograde movement to the endoplasmic reticulum.
    Cell biology and toxicology, 1999, Volume: 15, Issue:5

    Topics: Animals; Antineoplastic Agents; Biological Transport; Cells, Cultured; Clofibrate; Cytochrome P-450 Enzyme System; Diethylhexyl Phthalate; Endoplasmic Reticulum; Fatty Acids; Fluorescent Antibody Technique; Golgi Apparatus; Hypolipidemic Agents; Liver; Mannosidases; Membrane Glycoproteins; Microtubules; Nocodazole; Peroxisome Proliferators; Peroxisomes; Pyrimidines; Rats; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Viral Envelope Proteins

1999
Effects of peroxisome proliferators on the thymus and spleen of mice.
    Clinical and experimental immunology, 2000, Volume: 122, Issue:2

    Topics: Animals; Aspirin; Atrophy; B-Lymphocytes; Caprylates; Cell Cycle; Cell Division; Diethylhexyl Phthalate; DNA; Fluorocarbons; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Nafenopin; Peroxisome Proliferators; Pyrimidines; Spleen; T-Lymphocytes; Thymus Gland

2000
Mono-(2-ethylhexyl) phthalate suppresses aromatase transcript levels and estradiol production in cultured rat granulosa cells.
    Toxicology and applied pharmacology, 2001, May-01, Volume: 172, Issue:3

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Aromatase; Aromatase Inhibitors; Blotting, Western; Cells, Cultured; Cholesterol Side-Chain Cleavage Enzyme; Diethylhexyl Phthalate; Diethylstilbestrol; Enzyme Inhibitors; Estradiol; Female; Gonadotropins, Equine; Granulosa Cells; Peroxisome Proliferators; Pyrimidines; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2001
Peroxisome proliferator-activated receptor alpha (PPAR alpha) agonist, WY-14,643, increased transcription of myosin light chain-2 in cardiomyocytes.
    The Journal of toxicological sciences, 2001, Volume: 26, Issue:5

    Topics: Animals; Body Weight; Cardiac Myosins; Cell Line; Clofibrate; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Heart; Immunohistochemistry; Male; Myocardium; Myosin Light Chains; Organ Size; Peroxisome Proliferators; Proteins; Pyrimidines; Rats; Rats, Inbred F344; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Transcription, Genetic

2001
Sustained formation of alpha-(4-pyridyl-1-oxide)-N-tert-butylnitrone radical adducts in mouse liver by peroxisome proliferators is dependent upon peroxisome proliferator-activated receptor-alpha, but not NADPH oxidase.
    Free radical biology & medicine, 2007, Feb-01, Volume: 42, Issue:3

    Topics: Animals; Diethylhexyl Phthalate; Free Radicals; Kupffer Cells; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Peroxisome Proliferators; PPAR alpha; Pyridines; Pyrimidines; Reactive Oxygen Species

2007
Mechanisms of peroxisome proliferator-induced DNA hypomethylation in rat liver.
    Mutation research, 2008, Sep-26, Volume: 644, Issue:1-2

    Topics: Animals; Cell Proliferation; Diethylhexyl Phthalate; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Breaks, Single-Stranded; DNA Methylation; Histones; Liver; Male; Methylation; Mutagens; Peroxisome Proliferators; Proliferating Cell Nuclear Antigen; Pyrimidines; Rats; Rats, Inbred F344

2008
Clinically relevant concentrations of di (2-ethylhexyl) phthalate (DEHP) uncouple cardiac syncytium.
    Toxicology and applied pharmacology, 2009, Apr-01, Volume: 236, Issue:1

    Topics: Action Potentials; Animals; Animals, Newborn; Cadherins; Calcium Signaling; Cell Communication; Cells, Cultured; Connexin 43; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Fibroblasts; Gap Junctions; Myocardial Contraction; Myocytes, Cardiac; Paxillin; Plasticizers; PPAR alpha; Pyrimidines; Rats; Rats, Sprague-Dawley; Time Factors; Vimentin

2009
26-Week carcinogenicity study of di-isodecyl phthalate by dietary administration to CB6F1-rasH2 transgenic mice.
    Archives of toxicology, 2011, Volume: 85, Issue:1

    Topics: Adenoma, Liver Cell; Administration, Oral; Animals; Carcinogenicity Tests; Carcinogens; Clofibrate; Diethylhexyl Phthalate; Disease Models, Animal; Female; Genes, ras; Liver Neoplasms, Experimental; Male; Methylnitrosourea; Mice; Mice, Transgenic; Phthalic Acids; Pyrimidines; Time Factors

2011
Exposure to phthalates affects calcium handling and intercellular connectivity of human stem cell-derived cardiomyocytes.
    PloS one, 2015, Volume: 10, Issue:3

    Topics: Calcium; Connexin 43; Diethylhexyl Phthalate; Extracellular Space; Gene Expression Regulation; Heart Rate; Humans; Intracellular Space; Myocardial Contraction; Myocytes, Cardiac; Peroxisome Proliferator-Activated Receptors; Pyrimidines; Sarcoplasmic Reticulum; Stem Cells

2015