Compounds > pirinixic acid
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pirinixic acid and carbon tetrachloride

pirinixic acid has been researched along with carbon tetrachloride in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (22.22)18.2507
2000's2 (22.22)29.6817
2010's5 (55.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Cattley, RC; Glover, SE; Miller, RT; Murkofsky, RL; Popp, JA1
Conway, JG; Popp, JA1
Anderson, SP; Bahnemann, R; Corton, JC; Howroyd, P; Kensler, TW; Kwak, MK; Liu, J; Qian, X; Swanson, C1
Chipman, JK; Cowles, C; Mally, A1
Di, HL; Du, JH; Kong, LB; Li, WC; Li, Y; Nan, YM; Ren, WG; Wang, RQ; Wu, WJ; Yu, J; Zhang, YG; Zhao, SX1

Other Studies

9 other study(ies) available for pirinixic acid and carbon tetrachloride

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Effect of regeneration and hyperplasia on levels of DNA base oxidation in rat liver.
    Cancer letters, 1993, Jun-15, Volume: 70, Issue:1-2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Carbon Tetrachloride; Cell Division; Deoxyguanosine; Hyperplasia; Liver; Liver Regeneration; Male; Oxidation-Reduction; Phenobarbital; Pyrimidines; Rats; Rats, Inbred F344

1993
Effect of the hepatocarcinogenic peroxisome proliferator Wy-14,643 in vivo: no increase in ethane exhalation or hepatic conjugated dienes.
    Toxicology and applied pharmacology, 1995, Volume: 135, Issue:2

    Topics: Alkenes; Animals; Breath Tests; Carbon Tetrachloride; Carcinogens; Ethane; Fasting; Lipid Peroxidation; Lipids; Liver; Male; Microbodies; Pentanes; Pyrimidines; Rats; Rats, Inbred F344; Transaminases

1995
The transcriptional response to a peroxisome proliferator-activated receptor alpha agonist includes increased expression of proteome maintenance genes.
    The Journal of biological chemistry, 2004, Dec-10, Volume: 279, Issue:50

    Topics: Animals; Base Sequence; Cadmium; Carbon Tetrachloride; DNA; Female; Gene Expression Profiling; Hepatocytes; In Vitro Techniques; Lipid Metabolism; Male; Mice; Mice, Knockout; Oligonucleotide Array Sequence Analysis; Oxidative Stress; Paraquat; PPAR alpha; Proteome; Pyrimidines; Transcription, Genetic

2004
Different mechanisms of modulation of gap junction communication by non-genotoxic carcinogens in rat liver in vivo.
    Toxicology, 2007, Aug-16, Volume: 238, Issue:1

    Topics: Administration, Oral; Alanine Transaminase; Animals; Carbon Tetrachloride; Carcinogens; Cell Communication; Cell Proliferation; Connexin 26; Connexins; DDT; Dose-Response Relationship, Drug; Gap Junction beta-1 Protein; Gap Junctions; Hepatocytes; Immunoblotting; Injections, Intraperitoneal; Liver; Male; Palmitoyl Coenzyme A; Peroxisomes; Phosphorylation; Pyrimidines; Rats; Rats, Wistar

2007
Activation of peroxisome proliferator activated receptor alpha ameliorates ethanol mediated liver fibrosis in mice.
    Lipids in health and disease, 2013, Feb-06, Volume: 12

    Topics: Adiponectin; Animals; Anticholesteremic Agents; Carbon Tetrachloride; Cytokines; Ethanol; Gene Expression Regulation; Heme Oxygenase-1; Hepatic Stellate Cells; Hepatocytes; Interleukin-10; Liver; Liver Cirrhosis; Male; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Nicotinamide Phosphoribosyltransferase; Osteopontin; PPAR alpha; Pyrimidines; Signal Transduction; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha

2013