Page last updated: 2024-08-23

pirfenidone and acetylcysteine

pirfenidone has been researched along with acetylcysteine in 44 studies

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (13.64)29.6817
2010's34 (77.27)24.3611
2020's4 (9.09)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Flaherty, KR; Lynch, JP; Martinez, FJ; Thannickal, VJ1
Nathan, SD1
Eickelberg, O; Günther, A; Markart, P; Seeger, W1
Collard, HR; King, TE; Walter, N1
Azuma, A1
Bast, A; den Hartog, GJ; Haenen, GR; Weseler, AR1
Demedts, MG; Thomeer, M; Wuyts, WA1
Behr, J1
Abbasi, H; Aran, S; Ghaffari, A; Keshavarz, A; Seifirad, S; Taslimi, S1
Adamali, HI; Maher, TM1
Lota, HK; Wells, AU1
Ancochea, J; Bollo, E; Fernández-Fabrellas, E; Franquet, T; Molina-Molina, M; Montero, MA; Serrano-Mollar, A; Xaubet, A1
Kondoh, Y; Taniguchi, H1
Homma, S; Ishida, F; Isobe, K; Itoh, T; Muramatsu, Y; Sakamoto, S; Satoh, K; Sugino, K1
Alicic, RZ; Tuttle, KR1
Collard, HR; Ryerson, CJ1
Ehlers-Tenenbaum, S; Herth, FJ; Heussel, CP; Kahn, N; Kreuter, M; Oltmanns, U; Palmowski, K; Puderbach, M; Schnabel, PA; Träger, A; Warth, A; Wenz, H; Wiebel, M1
Kang, S1
Covvey, JR; Mancl, EE1
Cottin, V1
Homma, S; Sakamoto, S; Sugino, K1
Homma, S; Ishida, F; Isobe, K; Kikuchi, N; Muramatsu, Y; Sakamoto, S; Sano, G; Satoh, K; Sugino, K; Takai, Y1
Einecke, D1
Andreas, S; Bahmer, T; Behr, J; Claussen, M; Gläser, S; Grohé, C; Held, M; Herth, FJ; Hoeper, MM; Höffken, G; Huber, RM; Kirschner, J; Klotsche, J; Koch, A; Kohlhäufl, M; Koschel, D; Kreuter, M; Meyer, FJ; Neurohr, C; Pittrow, D; Randerath, W; Schwaiblmair, M; Skowasch, D; Welte, T; Wilkens, H; Wirtz, H1
Clegg, AJ; Colquitt, JL; Copley, VR; Loveman, E; O'Reilly, KM; Scott, DA1
Álvarez-Sala Walther, R; Gómez Carrera, L1
Canestaro, WJ; Devine, BE; Forrester, SH; Ho, L; Raghu, G1
Beyene, J; Brozek, J; Garcia, CC; Neupane, B; Raghu, G; Richeldi, L; Rochwerg, B; Schünemann, H; Zhang, Y1
Albera, C; Beck, J; Behr, J; Bendstrup, E; Crestani, B; Günther, A; Koschel, D; Kreuter, M; Lin, CY; Olschewski, H; Sköld, CM; Wallaert, B; Wells, A; Wuyts, W1
Ali, SA; Batra, SK; Chakraborty, S; Das, B; Dash, P; Jain, S; Mohanty, AK; Panda, SK; Senapati, S; Suklabaidya, S; Swaminathan, S1
Calzetta, L; Cavalli, F; Cazzola, M; Matera, MG; Rogliani, P1
Biju, G; Jyothi, E; Kumar, NK; Narayan, KV; Suraj, KP1
Guo, F; Song, X; Yu, W1
Chang, S; Diamantopoulos, A; Esser, D; LeReun, C; Maher, TM; Rinciog, C; Watkins, M1
Bellon, H; Heigl, T; Hoet, P; Lammertyn, E; Mathyssen, C; Pilette, C; Sacreas, A; Vanaudenaerde, BM; Vandermeulen, E; Verleden, GM; Verleden, SE; Vos, R; Vriens, H1
Behr, J; Bonella, F; Costabel, U; Geißler, K; Günther, A; Koschel, D; Kreuter, M; Müller-Quernheim, J; Prasse, A; Schönfeld, N; Sitter, H1
Azuma, A; Bando, M; Date, H; Ebina, M; Fukuoka, J; Gemma, A; Goto, Y; Hasegawa, Y; Hattori, N; Homma, S; Inase, N; Inoue, Y; Ishii, Y; Izumi, S; Johkoh, T; Kido, T; Kishaba, T; Kishi, K; Miyamoto, A; Mukae, H; Nakayama, T; Nishioka, Y; Ogura, T; Sakamoto, S; Sasaki, S; Suda, T; Sugino, K; Taguchi, Y; Takahashi, H; Takahashi, K; Taniguchi, H; Watanabe, K; Yokoyama, A; Yoshino, I1
Liu, JP; Lv, XD; Pang, LJ1
Bonella, F; Kreuter, M; Li, X; Oltmanns, U; Peng, S; Shi, H; Wei, L; Yin, D1
Bando, M; Hattori, N; Homma, S; Inase, N; Johkoh, T; Kataoka, K; Kato, M; Kishaba, T; Kishi, K; Kondoh, Y; Kuwano, K; Mukae, H; Nishioka, Y; Okamoto, M; Saito, T; Sakai, F; Sakamoto, S; Sasaki, S; Suda, T; Taguchi, Y; Takizawa, H; Tanino, Y; Yatera, K1
Li, SQ; Zou, H1
Cao, Y; Zhang, XL; Zheng, B1

Reviews

21 review(s) available for pirfenidone and acetylcysteine

ArticleYear
Idiopathic pulmonary fibrosis: emerging concepts on pharmacotherapy.
    Expert opinion on pharmacotherapy, 2004, Volume: 5, Issue:8

    Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Connective Tissue Growth Factor; Eicosanoids; Endothelin-1; Humans; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Interferon-gamma; Molybdenum; Protein Kinase Inhibitors; Proteins; Pulmonary Fibrosis; Pyridones; Recombinant Proteins; Relaxin; Renin-Angiotensin System; Tumor Necrosis Factor-alpha

2004
Therapeutic management of idiopathic pulmonary fibrosis: an evidence-based approach.
    Clinics in chest medicine, 2006, Volume: 27, Issue:1 Suppl 1

    Topics: Acetylcysteine; Azathioprine; Benzamides; Bosentan; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Etanercept; Evidence-Based Medicine; Humans; Imatinib Mesylate; Immunoglobulin G; Interferon-gamma; Piperazines; Prednisone; Pulmonary Fibrosis; Pyridones; Pyrimidines; Receptors, Tumor Necrosis Factor; Sulfonamides

2006
[Pulmonary fibrosis--a therapeutic dilemma?].
    Medizinische Klinik (Munich, Germany : 1983), 2006, Apr-15, Volume: 101, Issue:4

    Topics: Acetylcysteine; Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Benzamides; Bosentan; Cyclophosphamide; Drug Therapy, Combination; Etanercept; Free Radical Scavengers; Humans; Imatinib Mesylate; Immunoglobulin G; Immunosuppressive Agents; Interferon-gamma; Lung Transplantation; Piperazines; Protein Kinase Inhibitors; Pulmonary Fibrosis; Pyridones; Pyrimidines; Randomized Controlled Trials as Topic; Receptors, Tumor Necrosis Factor; Sulfonamides

2006
Current perspectives on the treatment of idiopathic pulmonary fibrosis.
    Proceedings of the American Thoracic Society, 2006, Volume: 3, Issue:4

    Topics: Acetylcysteine; Anticoagulants; Azathioprine; Clinical Trials as Topic; Cyclophosphamide; Humans; Immunosuppressive Agents; Interferon-gamma; Lung Transplantation; Prednisone; Pulmonary Fibrosis; Pyridones; Quality of Life; Recombinant Proteins

2006
[Newly developed therapeutic drugs for idiopathic interstitial pneumonias].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2006, Jun-10, Volume: 95, Issue:6

    Topics: Acetylcysteine; Drug Design; Drug Therapy, Combination; Humans; Interferon-gamma; Lung Diseases, Interstitial; Prednisolone; Pyridones; Randomized Controlled Trials as Topic

2006
Oxidative stress and antioxidants in interstitial lung disease.
    Current opinion in pulmonary medicine, 2010, Volume: 16, Issue:5

    Topics: Acetylcysteine; Antioxidants; Humans; Lung Diseases, Interstitial; Oxidative Stress; Pyridones; Reactive Oxygen Species

2010
Newer modes of treating interstitial lung disease.
    Current opinion in pulmonary medicine, 2011, Volume: 17, Issue:5

    Topics: Acetylcysteine; Adrenal Cortex Hormones; Azathioprine; Humans; Lung Diseases, Interstitial; Lung Transplantation; Palliative Care; Pyridones

2011
[Idiopathic pulmonary fibrosis: modern guideline-concordant diagnostics and innovative treatment].
    Deutsche medizinische Wochenschrift (1946), 2012, Volume: 137, Issue:12

    Topics: Acetylcysteine; Algorithms; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Antioxidants; Biopsy; Expectorants; Humans; Idiopathic Pulmonary Fibrosis; Lung; Lung Transplantation; Oxygen Inhalation Therapy; Practice Guidelines as Topic; Pyridones; Tomography, X-Ray Computed

2012
Current and novel drug therapies for idiopathic pulmonary fibrosis.
    Drug design, development and therapy, 2012, Volume: 6

    Topics: Acetylcysteine; Amino Acid Oxidoreductases; Animals; Antiviral Agents; Gastroesophageal Reflux; Humans; Idiopathic Pulmonary Fibrosis; Interleukin-13; Lung Transplantation; MicroRNAs; Protein Kinase Inhibitors; Pyridones; Transforming Growth Factor beta

2012
The evolving pharmacotherapy of pulmonary fibrosis.
    Expert opinion on pharmacotherapy, 2013, Volume: 14, Issue:1

    Topics: Acetylcysteine; Anti-Inflammatory Agents, Non-Steroidal; Humans; Idiopathic Interstitial Pneumonias; Immunosuppressive Agents; Indoles; Lung Diseases, Interstitial; Pulmonary Fibrosis; Pyridones; Randomized Controlled Trials as Topic; Sarcoidosis, Pulmonary; Scleroderma, Systemic; Treatment Outcome

2013
Novel therapies for diabetic kidney disease.
    Advances in chronic kidney disease, 2014, Volume: 21, Issue:2

    Topics: Acetylcysteine; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antihypertensive Agents; Antioxidants; Bosentan; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Endothelins; Enzyme Inhibitors; Glycation End Products, Advanced; Humans; Hypoglycemic Agents; Indoles; Janus Kinases; Maleimides; Polyamines; Protein Kinase C; Pyridones; Pyridoxamine; Sevelamer; Sulfonamides

2014
Recent evidence for pharmacological treatment of idiopathic pulmonary fibrosis.
    The Annals of pharmacotherapy, 2014, Volume: 48, Issue:12

    Topics: Acetylcysteine; Anti-Inflammatory Agents; Azathioprine; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Prednisone; Pyridones; Randomized Controlled Trials as Topic

2014
Usefulness of a disease severity staging classification system for IPF in Japan: 20 years of experience from empirical evidence to randomized control trial enrollment.
    Respiratory investigation, 2015, Volume: 53, Issue:1

    Topics: Acetylcysteine; Empirical Research; Evidence-Based Medicine; Humans; Idiopathic Pulmonary Fibrosis; Japan; Oximetry; Patient Selection; Pyridones; Randomized Controlled Trials as Topic; Severity of Illness Index; Time Factors; Vital Capacity

2015
Comparing new treatments for idiopathic pulmonary fibrosis--a network meta-analysis.
    BMC pulmonary medicine, 2015, Apr-18, Volume: 15

    Topics: Acetylcysteine; Anti-Inflammatory Agents, Non-Steroidal; Enzyme Inhibitors; Free Radical Scavengers; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; Treatment Outcome

2015
Drug Treatment of Idiopathic Pulmonary Fibrosis: Systematic Review and Network Meta-Analysis.
    Chest, 2016, Volume: 149, Issue:3

    Topics: Acetylcysteine; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Azathioprine; Bayes Theorem; Bosentan; Endothelin Receptor Antagonists; Enzyme Inhibitors; Etanercept; Free Radical Scavengers; Humans; Idiopathic Pulmonary Fibrosis; Imatinib Mesylate; Immunosuppressive Agents; Indoles; Interferon-gamma; Phenylpropionates; Pyridazines; Pyridones; Pyrimidines; Recombinant Proteins; Sulfonamides; Vital Capacity; Warfarin

2016
Treatment of idiopathic pulmonary fibrosis: a network meta-analysis.
    BMC medicine, 2016, Feb-03, Volume: 14

    Topics: Acetylcysteine; Adult; Anticoagulants; Bayes Theorem; Female; Free Radical Scavengers; Humans; Idiopathic Pulmonary Fibrosis; Immunosuppressive Agents; Indoles; Male; Middle Aged; Pyridones; Quality of Life; Treatment Outcome; Young Adult

2016
Pirfenidone, nintedanib and N-acetylcysteine for the treatment of idiopathic pulmonary fibrosis: A systematic review and meta-analysis.
    Pulmonary pharmacology & therapeutics, 2016, Volume: 40

    Topics: Acetylcysteine; Anti-Inflammatory Agents; Enzyme Inhibitors; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Practice Guidelines as Topic; Pyridones; Randomized Controlled Trials as Topic; Treatment Outcome

2016
A Cost-Effectiveness Analysis of Nintedanib in Idiopathic Pulmonary Fibrosis in the UK.
    PharmacoEconomics, 2017, Volume: 35, Issue:4

    Topics: Acetylcysteine; Adult; Cost-Benefit Analysis; Enzyme Inhibitors; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Markov Chains; Models, Economic; Pyridones; Quality of Life; Quality-Adjusted Life Years; Randomized Controlled Trials as Topic; Treatment Outcome; United Kingdom

2017
Japanese guideline for the treatment of idiopathic pulmonary fibrosis.
    Respiratory investigation, 2018, Volume: 56, Issue:4

    Topics: Acetylcysteine; Administration, Inhalation; Adrenal Cortex Hormones; Antineoplastic Combined Chemotherapy Protocols; Comorbidity; Disease Progression; Drug Therapy, Combination; Evidence-Based Medicine; Glycine; Humans; Idiopathic Pulmonary Fibrosis; Immunosuppressive Agents; Indoles; Japan; Lung Neoplasms; Meta-Analysis as Topic; Practice Guidelines as Topic; Prognosis; Pyridones; Quality of Health Care; Sulfonamides; Survival Rate

2018
Efficacy, safety, and tolerability of combined pirfenidone and N-acetylcysteine therapy: a systematic review and meta-analysis.
    BMC pulmonary medicine, 2020, May-07, Volume: 20, Issue:1

    Topics: Acetylcysteine; Administration, Inhalation; Anti-Inflammatory Agents, Non-Steroidal; Carbon Monoxide; Drug Therapy, Combination; Free Radical Scavengers; Humans; Idiopathic Pulmonary Fibrosis; Pyridones; Randomized Controlled Trials as Topic; Treatment Outcome; Vital Capacity

2020
Efficacy of N-acetylcysteine plus pirfenidone in the treatment of idiopathic pulmonary fibrosis: a systematic review and meta-analysis.
    BMC pulmonary medicine, 2023, Nov-29, Volume: 23, Issue:1

    Topics: Acetylcysteine; Humans; Idiopathic Pulmonary Fibrosis; Pyridones; Treatment Outcome

2023

Trials

2 trial(s) available for pirfenidone and acetylcysteine

ArticleYear
Safety and tolerability of acetylcysteine and pirfenidone combination therapy in idiopathic pulmonary fibrosis: a randomised, double-blind, placebo-controlled, phase 2 trial.
    The Lancet. Respiratory medicine, 2016, Volume: 4, Issue:6

    Topics: Acetylcysteine; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Drug Therapy, Combination; Europe; Expectorants; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Pyridones; Treatment Outcome

2016
Pirfenidone plus inhaled N-acetylcysteine for idiopathic pulmonary fibrosis: a randomised trial.
    The European respiratory journal, 2021, Volume: 57, Issue:1

    Topics: Acetylcysteine; Anti-Inflammatory Agents, Non-Steroidal; Humans; Idiopathic Pulmonary Fibrosis; Japan; Pyridones; Treatment Outcome; Vital Capacity

2021

Other Studies

21 other study(ies) available for pirfenidone and acetylcysteine

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Effect of pirfenidone on pulmonary fibrosis due to paraquat poisoning in rats.
    Clinical toxicology (Philadelphia, Pa.), 2012, Volume: 50, Issue:8

    Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Ascorbic Acid; Disease Models, Animal; Herbicides; Injections, Intraperitoneal; Injections, Intravenous; Life Expectancy; Male; Paraquat; Pulmonary Fibrosis; Pyridones; Rats; Rats, Wistar; Survival Rate; Vitamin E

2012
Guidelines for the diagnosis and treatment of idiopathic pulmonary fibrosis. Sociedad Española de Neumología y Cirugía Torácica (SEPAR) Research Group on Diffuse Pulmonary Diseases.
    Archivos de bronconeumologia, 2013, Volume: 49, Issue:8

    Topics: Acetylcysteine; Biopsy; Bronchoalveolar Lavage Fluid; Cell- and Tissue-Based Therapy; Clinical Trials as Topic; Contraindications; Diagnostic Imaging; Disease Progression; Evidence-Based Medicine; Gastroesophageal Reflux; Genetic Therapy; Glucocorticoids; Humans; Hypertension, Pulmonary; Idiopathic Pulmonary Fibrosis; Immunologic Factors; Incidence; Indoles; Lung; Lung Transplantation; Oxygen Inhalation Therapy; Palliative Care; Prevalence; Prognosis; Pulmonary Emphysema; Pyridones; Risk Factors; Spain

2013
Combination therapies targeting multiple pathways in idiopathic pulmonary fibrosis (IPF).
    Internal medicine (Tokyo, Japan), 2013, Volume: 52, Issue:22

    Topics: Acetylcysteine; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Drug Therapy, Combination; Free Radical Scavengers; Humans; Idiopathic Pulmonary Fibrosis; Pyridones; Vital Capacity

2013
Efficacy of pirfenidone in patients with advanced-stage idiopathic pulmonary fibrosis.
    Internal medicine (Tokyo, Japan), 2013, Volume: 52, Issue:22

    Topics: Acetylcysteine; Administration, Inhalation; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Disease Progression; Drug Therapy, Combination; Female; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Pyridones; Retrospective Studies; Treatment Outcome; Vital Capacity

2013
Hot off the breath: A big step forward for idiopathic pulmonary fibrosis.
    Thorax, 2014, Volume: 69, Issue:9

    Topics: Acetylcysteine; Anti-Inflammatory Agents, Non-Steroidal; Enzyme Inhibitors; Free Radical Scavengers; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; Randomized Controlled Trials as Topic

2014
Pirfenidone in idiopathic pulmonary fibrosis: real-life experience from a German tertiary referral center for interstitial lung diseases.
    Respiration; international review of thoracic diseases, 2014, Volume: 88, Issue:3

    Topics: Acetylcysteine; Adrenal Cortex Hormones; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cohort Studies; Disease Progression; Drug Eruptions; Drug Therapy, Combination; Expectorants; Fatigue; Female; Gastrointestinal Diseases; Germany; Humans; Idiopathic Pulmonary Fibrosis; Male; Medication Adherence; Middle Aged; Pyridones; Retrospective Studies; Tertiary Care Centers; Treatment Outcome; Vital Capacity; Weight Loss

2014
2014 American Thoracic Society International Conference.
    The Lancet. Respiratory medicine, 2014, Volume: 2, Issue:7

    Topics: Acetylcysteine; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal, Humanized; Asthma; Congresses as Topic; Eosinophilia; Expectorants; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Idiopathic Pulmonary Fibrosis; Indoles; Lung Neoplasms; Protein Kinase Inhibitors; Pulmonary Disease, Chronic Obstructive; Pyridones; Respiratory Distress Syndrome

2014
[Idiopathic pulmonary fibrosis: A new era, new challenges].
    Revue des maladies respiratoires, 2014, Volume: 31, Issue:7

    Topics: Acetylcysteine; Clinical Trials as Topic; Free Radical Scavengers; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones

2014
Effectiveness of combined therapy with pirfenidone and inhaled N-acetylcysteine for advanced idiopathic pulmonary fibrosis: a case-control study.
    Respirology (Carlton, Vic.), 2015, Volume: 20, Issue:3

    Topics: Acetylcysteine; Administration, Inhalation; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Free Radical Scavengers; Humans; Idiopathic Pulmonary Fibrosis; Male; Middle Aged; Pyridones; Retrospective Studies; Treatment Outcome; Vital Capacity

2015
[Two drugs inhibit disease progression. Idiopathic lung fibrosis treatable for the first time].
    MMW Fortschritte der Medizin, 2015, Feb-05, Volume: 157, Issue:2

    Topics: Acetylcysteine; Disease Progression; Idiopathic Pulmonary Fibrosis; Indoles; Pyridones; Randomized Controlled Trials as Topic; Survival Analysis; Vital Capacity

2015
Management of patients with idiopathic pulmonary fibrosis in clinical practice: the INSIGHTS-IPF registry.
    The European respiratory journal, 2015, Volume: 46, Issue:1

    Topics: Acetylcysteine; Aged; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Exercise Test; Female; Germany; Humans; Idiopathic Pulmonary Fibrosis; Lung; Male; Middle Aged; Practice Guidelines as Topic; Prospective Studies; Pyridones; Registries; Steroids; Tomography, X-Ray Computed; Vital Capacity

2015
[Pulmonary fibrosis].
    Medicina clinica, 2016, Feb-05, Volume: 146, Issue:3

    Topics: Acetylcysteine; Azathioprine; Clinical Trials as Topic; Forecasting; Glucocorticoids; Humans; Indoles; Multicenter Studies as Topic; Prognosis; Pulmonary Fibrosis; Pyridones

2016
Characterization and use of HapT1-derived homologous tumors as a preclinical model to evaluate therapeutic efficacy of drugs against pancreatic tumor desmoplasia.
    Oncotarget, 2016, Jul-05, Volume: 7, Issue:27

    Topics: Acetylcysteine; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Disulfiram; Fibrosis; Guinea Pigs; Humans; Pancreas; Pancreatic Neoplasms; Pancreatic Stellate Cells; Pyridones; Rats; Xenograft Model Antitumor Assays

2016
Role of Pirfenidone in Idiopathic Pulmonary Fibrosis - A Longitudinal Cohort Study.
    The Journal of the Association of Physicians of India, 2016, Volume: 64, Issue:5

    Topics: Acetylcysteine; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; Cohort Studies; Drug Therapy, Combination; Female; Humans; Idiopathic Pulmonary Fibrosis; Longitudinal Studies; Male; Middle Aged; Proton Pump Inhibitors; Pyridones; Treatment Outcome

2016
Effects and mechanisms of pirfenidone, prednisone and acetylcysteine on pulmonary fibrosis in rat idiopathic pulmonary fibrosis models.
    Pharmaceutical biology, 2017, Volume: 55, Issue:1

    Topics: Acetylcysteine; Animals; Bleomycin; Blotting, Western; Caveolin 1; Cytoprotection; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Idiopathic Pulmonary Fibrosis; Lung; Male; Platelet-Derived Growth Factor; Prednisone; Protective Agents; Pyridones; Rats, Wistar; Real-Time Polymerase Chain Reaction; Signal Transduction; Time Factors; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha

2017
Interleukin-1α induced release of interleukin-8 by human bronchial epithelial cells in vitro: assessing mechanisms and possible treatment options.
    Transplant international : official journal of the European Society for Organ Transplantation, 2017, Volume: 30, Issue:4

    Topics: Acetates; Acetylcysteine; Aminopyridines; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Azithromycin; Benzamides; Bronchi; Cell Line; Cyclopropanes; Dapsone; Dexamethasone; Dose-Response Relationship, Drug; Epithelial Cells; Fluoroquinolones; Humans; Interleukin-1alpha; Interleukin-8; MAP Kinase Signaling System; Moxifloxacin; Neutrophils; Phosphorylation; Pyridones; Quinolines; Sulfides; Theophylline; Treatment Outcome

2017
German Guideline for Idiopathic Pulmonary Fibrosis - Update on Pharmacological Therapies 2017.
    Pneumologie (Stuttgart, Germany), 2018, Volume: 72, Issue:2

    Topics: Acetylcysteine; Adult; Aged; Aged, 80 and over; Antacids; Bosentan; Clinical Trials as Topic; Evidence-Based Medicine; Female; Gastroesophageal Reflux; Guideline Adherence; Humans; Idiopathic Pulmonary Fibrosis; Imatinib Mesylate; Indoles; Male; Middle Aged; Phenylpropionates; Pyridazines; Pyridones; Pyrimidines; Sildenafil Citrate; Sulfonamides

2018
Comparative effectiveness of 3 Traditional Chinese Medicine treatment methods for idiopathic pulmonary fibrosis: A systematic review and network meta-analysis protocol.
    Medicine, 2019, Volume: 98, Issue:30

    Topics: Acetylcysteine; Anti-Inflammatory Agents, Non-Steroidal; Bayes Theorem; Drug Therapy, Combination; Drugs, Chinese Herbal; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Medicine, Chinese Traditional; Meta-Analysis as Topic; Network Meta-Analysis; Pyridones; Quality of Life; Randomized Controlled Trials as Topic; Research Design; Respiratory Function Tests; Severity of Illness Index; Survival Analysis; Systematic Reviews as Topic

2019
Pulmonary fibrosis in critically ill patients with novel coronavirus pneumonia during the convalescent stage and a proposal for early intervention.
    Acta pharmacologica Sinica, 2021, Volume: 42, Issue:8

    Topics: Acetylcysteine; Convalescence; COVID-19; COVID-19 Drug Treatment; Early Medical Intervention; Glucocorticoids; Humans; Indoles; Pulmonary Fibrosis; Pyridones; SARS-CoV-2

2021