pirarubicin has been researched along with bisantrene* in 1 studies
1 other study(ies) available for pirarubicin and bisantrene
Article | Year |
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Sensitivity of human pancreatic carcinoma cell line (MIA PaCa-2) to Bisantrene and Theprubicin in vitro.
We tested the effect of Bisantrene (BS) and Theprubicin (THP-ADR) on cell growth of a human pancreatic carcinoma cell line (MIA PaCa-2). After 1 h exposure ID50 of BS or THP-ADR was 3 X 10(-7) and 5 X 10(-8) M, respectively. Increasing the exposure time from 1 h to continuous exposure for 5d resulted in 11-fold decrease in ID50 for BS and a 6-fold decrease for THP-ADR. Both drugs inhibited [14C]thymidine incorporation to the same extent and caused an accumulation of cells into G2 + M phase of the cell cycle. Topics: Anthracenes; Antibiotics, Antineoplastic; Cell Division; Cell Line; DNA; Doxorubicin; Humans; Pancreatic Neoplasms | 1984 |