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piperonyl butoxide and phenobarbital

piperonyl butoxide has been researched along with phenobarbital in 64 studies

Research

Studies (64)

Timeframe	Studies, this research(%)	All Research%
pre-1990	43 (67.19)	18.7374
1990's	14 (21.88)	18.2507
2000's	1 (1.56)	29.6817
2010's	5 (7.81)	24.3611
2020's	1 (1.56)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Bray, TM; Carlson, JR	1
Sanders-Bush, E; Steranka, LR	1
Abernethy, DR; Azarnoff, DL	1
Mitchell, JR; Timbrell, JA	1
Couture, J; Dahlström-King, L; Plaa, GL	1
Pai, KS; Ravindranath, V	1
Hobara, T; Ishiyama, H; Kanbe, T; Ogino, K; Shimomura, Y	1
Bray, TM; Chen, GM; Janzen, EG; McCay, PB	1
Chambers, HW; Chambers, JE	1
Hashimoto, K; Sakamoto, J	1
Haim, N; Nemec, J; Roman, J; Sinha, BK	1
Colby, HD; Dalal, NS; LaCagnin, LB; O'Donnell, JP	1
Fujita, S; Mizutani, T; Nakanishi, K; Nomura, H	1
Becker, E; Berndt, J; Messner, B	1
Brown, PI; Rankin, GO; Richmond, CD; Teets, VJ; Wang, RT; Yang, DJ	1
Kocsis, JJ; Kyle, ME	1
Gram, TE; Okine, LK	1
Lindup, WE; Orton, TC; Rosenbaum, SE	1
Boyd, MR; Kramer, RA; McMenamin, MG	1
Flory, W; Henk, WG; Turk, MA	1
Amouyal, G; Degott, C; Descatoire, V; Geneve, J; Larrey, D; Letteron, P; Pessayre, D; Tinel, M	1
Boyd, MR; Ravindranath, V	1
Brodie, BB; Davis, DC; Gillette, JR; Jollow, DJ; Mitchell, JR; Potter, WZ	3
Jollow, DJ; Mitchell, JR; Potter, WZ; Thorgeirsson, SS	1
Hashimoto, M; Jollow, DJ; Mitchell, JR; Potter, WZ; Thorgeirsson, SS	1
Krishna, G; Reid, WD	1
Glick, JM; Ilett, KF; Krishna, G; Reid, WD	1
Reid, WD	1
Ilett, KF; Krishna, G; Reid, WD; Sipes, IG	1
Couch, DB; Friedman, MA	1
Levine, WG	1
Brodie, BB; Christie, B; Krishna, G; Mitchell, JR; Moskowitz, J; Reid, WD	1
Hook, JB; Kuo, CH	1
Bray, TM; Burley, FE	1
Breeze, RG; Laegreid, WW; Olcott, BM	1
Bahnson, LS; Buckpitt, AR; Franklin, RB	1
Imamura, T	1
Belghiti, J; Danan, G; Fouin-Fortunet, H; Lettéron, P; Pessayre, D; Tinel, M	1
Hasegawa, L; Imamura, T	1
Chakrabarti, S; Law, FC	1
Clark, JD; Hatch, RC; Jain, AV; Weiss, R	2
Fukuto, TR; Gandy, J; Hasegawa, L; Imamura, T	1
Breger, RK; Franklin, RB; Griffin, KA; Johnson, CB	1
Massey, TE; McElligott, TF; Racz, WJ; Walker, RM	1
Bridges, JW; Fennell, TR; Sweatman, BC	1
Brown, PI; Lo, HH; Rankin, GO; Valentovic, MA	1
Pai, KS; Ravindranath, V; Sriram, K	1
Jenner, AM; Timbrell, JA	1
Anestis, DK; Beers, KW; Brown, PI; Nicoll, DW; Rankin, GO	1
Belitsky, GA; Spiegelman, VS	1
Drummond, J; Kotze, AC; Levot, GW; Pinnock, DE	1
Kotze, AC	1
Butler, WH; Cockburn, A; Cunninghame, ME; Gabriel, KL; Lake, BG; Osimitz, TG; Phillips, JC; Preiss, FJ; Price, RJ	1
Imazawa, T; Ito, S; Mitsumori, K; Okamiya, H; Onodera, H; Takahashi, M; Yasuhara, K	1
Berenbaum, MR; Niu, G; Schuler, MA; Wen, Z; Zeng, RS	1
Hibi, D; Inoue, T; Ishii, Y; Maruyama, S; Nishikawa, A; Nohmi, T; Okamura, T; Suzuki, Y; Tasaki, M; Umemura, T	1
Degawa, M; Gamou, T; Habano, W; Hikida, T; Ikeda, A; Inoue, K; Ito, S; Mizukami, M; Nemoto, K; Nishikawa, A; Ozawa, S; Tanaka, T; Yoshida, M	1
Degawa, M; Fujimoto, N; Gamou, T; Inoue, K; Nemoto, K; Nishikawa, A; Ozawa, S; Yoshida, M	1
Akane, H; Itahashi, M; Mitsumori, K; Morita, R; Nakane, F; Shibutani, M; Shiraki, A; Suzuki, K; Yafune, A	1
Chatham, LR; Lake, BG; Osimitz, TG; Price, RJ; Scott, MP; Vardy, A	1

Other Studies

64 other study(ies) available for piperonyl butoxide and phenobarbital

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Role of mixed-function oxidase in 3-methylindole-induced acute pulmonary edema in goats. American journal of veterinary research, 1979, Volume: 40, Issue:9 Topics: Animals; Goats; Indoles; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital; Piperonyl Butoxide; Pulmonary Edema; Skatole	1979
Long-term reduction of brain serotonin by p-chloroamphetamine: effects of inducers and inhibitors of drug metabolism. The Journal of pharmacology and experimental therapeutics, 1978, Volume: 206, Issue:2 Topics: Amphetamines; Animals; Brain; Brain Chemistry; Depression, Chemical; Half-Life; Male; Methylcholanthrene; Microsomes, Liver; p-Chloroamphetamine; Phenobarbital; Piperonyl Butoxide; Propylamines; Rats; Serotonin; Serotonin Antagonists; Synaptosomes; Tryptophan Hydroxylase	1978
Effect of drugs which alter microsomal drug-metabolizing enzyme activity on rat hepatic cholesterol biosynthesis. Biochemical pharmacology, 1977, Mar-15, Volume: 26, Issue:6 Topics: Animals; Cholesterol; Cobalt; Cytochrome P-450 Enzyme System; Desmosterol; Hydroxymethylglutaryl CoA Reductases; Liver; Male; Metyrapone; Microsomes, Liver; Nitriles; Phenobarbital; Piperonyl Butoxide; Pregnenolone; Rats; Sterols	1977
Toxicity-related changes in benzene metabolism in vivo. Xenobiotica; the fate of foreign compounds in biological systems, 1977, Volume: 7, Issue:7 Topics: Acetylcysteine; Animals; Benzene; Breath Tests; Cobalt; Male; Phenobarbital; Phenols; Piperonyl Butoxide; Rats	1977
Influence of agents affecting monooxygenase activity on taurolithocholic acid-induced cholestasis. Toxicology letters, 1992, Volume: 63, Issue:3 Topics: Animals; Bile; Body Weight; Chlordecone; Cholestasis; Cobalt; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Synergism; Enzyme Induction; Ketones; Liver; Male; Methylcholanthrene; Mirex; Organ Size; Phenobarbital; Piperonyl Butoxide; Proadifen; Rats; Rats, Sprague-Dawley; Taurolithocholic Acid	1992
Protection and potentiation of MPTP-induced toxicity by cytochrome P-450 inhibitors and inducer: in vitro studies with brain slices. Brain research, 1991, Aug-02, Volume: 555, Issue:2 Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Brain; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Mice; Mixed Function Oxygenases; Monoamine Oxidase Inhibitors; MPTP Poisoning; NADPH-Ferrihemoprotein Reductase; Pargyline; Phenobarbital; Piperazines; Piperonyl Butoxide; Proadifen; Selegiline	1991
Hepatotoxicity of diethyldithiocarbamate in rats. Pharmacology & toxicology, 1990, Volume: 67, Issue:5 Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Catalase; Deferoxamine; Ditiocarb; Glutathione; Injections, Subcutaneous; Liver; Liver Circulation; Male; Necrosis; Phenobarbital; Piperonyl Butoxide; Rats; Rats, Inbred Strains; Superoxide Dismutase; Thiobarbiturates	1990
The role of mixed function oxidase (MFO) in the metabolism of the spin trapping agent alpha-phenyl-N-tert-butyl-nitrone (PBN) in rats. Free radical research communications, 1991, Volume: 14, Issue:1 Topics: Animals; Cyclic N-Oxides; Enzyme Induction; Kidney; Liver; Lung; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Mixed Function Oxygenases; NADP; Nitrogen Oxides; Phenobarbital; Piperonyl Butoxide; Rats; Rats, Inbred Strains; Spin Labels	1991
Time course of inhibition of acetylcholinesterase and aliesterases following parathion and paraoxon exposures in rats. Toxicology and applied pharmacology, 1990, Volume: 103, Issue:3 Topics: Animals; Benzoflavones; beta-Naphthoflavone; Brain; Carboxylesterase; Carboxylic Ester Hydrolases; Cholinesterase Inhibitors; Cytochrome P-450 Enzyme System; Environmental Exposure; Enzyme Induction; Female; Liver; Paraoxon; Parathion; Phenobarbital; Piperonyl Butoxide; Poisoning; Rats; Rats, Inbred Strains; Time Factors	1990
Effect of acrylamide and related compounds on glycolytic enzymes in mouse brain in vitro. Archives of toxicology, 1985, Volume: 57, Issue:4 Topics: Acrylamides; Animals; Brain; Brain Chemistry; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycolysis; In Vitro Techniques; Kinetics; Liver; Male; Mice; Mixed Function Oxygenases; Phenobarbital; Phosphofructokinase-1; Phosphopyruvate Hydratase; Piperonyl Butoxide; Subcellular Fractions	1985
In vitro metabolism of etoposide (VP-16-213) by liver microsomes and irreversible binding of reactive intermediates to microsomal proteins. Biochemical pharmacology, 1987, Feb-15, Volume: 36, Issue:4 Topics: Animals; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Etoposide; Mice; Microsomes, Liver; NADP; Phenobarbital; Piperonyl Butoxide; Proadifen; Proteins	1987
Metabolic activation of hydralazine by rat liver microsomes. Biochemical pharmacology, 1987, Aug-15, Volume: 36, Issue:16 Topics: Animals; Biotransformation; Electron Spin Resonance Spectroscopy; Hydralazine; Male; Methylcholanthrene; Microsomes, Liver; NADP; Phenobarbital; Piperonyl Butoxide; Rats; Rats, Inbred Strains	1987
Effects of drug metabolism modifiers on pulegone-induced hepatotoxicity in mice. Research communications in chemical pathology and pharmacology, 1987, Volume: 58, Issue:1 Topics: Animals; Biotransformation; Carbon Disulfide; Chemical and Drug Induced Liver Injury; Cyclohexane Monoterpenes; Liver; Male; Menthol; Metyrapone; Mice; Mice, Inbred Strains; Monoterpenes; Oxidation-Reduction; Phenobarbital; Piperonyl Butoxide; Pyridines	1987
Two mechanisms of CCl4-induced fatty liver: lipid peroxidation or covalent binding studied in cultured rat hepatocytes. Free radical research communications, 1987, Volume: 3, Issue:1-5 Topics: Animals; Binding, Competitive; Carbon Tetrachloride; Cells, Cultured; Fatty Liver; Female; Lipid Peroxidation; Lipoproteins, HDL; Lipoproteins, VLDL; Liver; Malondialdehyde; Phenobarbital; Piperonyl Butoxide; Rats; Rats, Inbred Strains; Vitamin E	1987
Effect of microsomal enzyme activity modulation on N-(3,5-dichlorophenyl)succinimide-induced nephrotoxicity. Toxicology, 1987, Volume: 45, Issue:3 Topics: Animals; Drug Interactions; Enzyme Induction; Kidney; Male; Methylcholanthrene; Microsomes; Phenobarbital; Piperonyl Butoxide; Rats; Rats, Inbred F344; Rats, Inbred Strains; Species Specificity; Succinimides	1987
The effect of mixed function oxidase induction and inhibition on salicylate-induced nephrotoxicity in male rats. Toxicology and applied pharmacology, 1986, Jun-30, Volume: 84, Issue:2 Topics: Alanine Transaminase; Animals; Aroclors; Blood Urea Nitrogen; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Cytosol; Drug Interactions; Enzyme Induction; Glucose; Injections, Intraperitoneal; Kidney; Male; Microsomes, Liver; Mitochondria, Liver; Mixed Function Oxygenases; Phenobarbital; Piperonyl Butoxide; Rats; Rats, Inbred Strains; Salicylates; Salicylic Acid	1986
In vitro studies on the metabolism and covalent binding of [14C]1,1-dichloroethylene by mouse liver, kidney and lung. Biochemical pharmacology, 1986, Aug-15, Volume: 35, Issue:16 Topics: Animals; Benzoflavones; beta-Naphthoflavone; Carbon Monoxide; Cytochrome P-450 Enzyme System; Dichloroethylenes; Enzyme Induction; Glutathione; Hot Temperature; Hydrocarbons, Chlorinated; In Vitro Techniques; Kidney; Liver; Lung; Methylcholanthrene; Mice; Mice, Inbred C57BL; NADP; Phenobarbital; Piperonyl Butoxide; Pregnenolone Carbonitrile; Proadifen; Subcellular Fractions	1986
Practolol: aspects of its metabolism and ocular binding in the hamster. Xenobiotica; the fate of foreign compounds in biological systems, 1986, Volume: 16, Issue:6 Topics: Animals; Cobalt; Cricetinae; Eye; Male; Mesocricetus; Mixed Function Oxygenases; Phenobarbital; Piperonyl Butoxide; Practolol	1986
In vivo studies on the relationship between hepatic metabolism and the renal toxicity of 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea (MeCCNU). Toxicology and applied pharmacology, 1986, Sep-15, Volume: 85, Issue:2 Topics: Animals; Bile; Carbon Radioisotopes; DNA; Glutathione; Kidney; Liver; Male; Nitrosourea Compounds; p-Aminohippuric Acid; Phenobarbital; Piperonyl Butoxide; Rats; Rats, Inbred F344; Semustine	1986
Chemical modulation of 3-methylindole toxicosis in mice: effect on bronchiolar and olfactory mucosal injury. Veterinary pathology, 1986, Volume: 23, Issue:5 Topics: Animals; Benzoflavones; beta-Naphthoflavone; Bronchi; Epithelium; Female; Flavonoids; Glutathione; Indoles; Male; Maleates; Mice; Mice, Inbred C57BL; Mixed Function Oxygenases; Nasal Mucosa; Phenobarbital; Piperonyl Butoxide; Proadifen; Sex Factors; Skatole	1986
Metabolic activation of the tricyclic antidepressant amineptine--II. Protective role of glutathione against in vitro and in vivo covalent binding. Biochemical pharmacology, 1987, Feb-01, Volume: 36, Issue:3 Topics: Animals; Antidepressive Agents, Tricyclic; Biotransformation; Buthionine Sulfoximine; Cricetinae; Dibenzocycloheptenes; Glutathione; Ketones; Kinetics; Male; Mesocricetus; Methionine Sulfoximine; Microsomes, Liver; NADP; Phenobarbital; Piperonyl Butoxide	1987
Metabolic activation of 2-methylfuran by rat microsomal systems. Toxicology and applied pharmacology, 1985, Volume: 78, Issue:3 Topics: Acrolein; Aldehydes; Animals; Biotransformation; Carbon Radioisotopes; Cytochrome P-450 Enzyme Inhibitors; Furans; Imidazoles; Kinetics; Lung; Male; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Piperonyl Butoxide; Rats; Rats, Inbred Strains	1985
Acetaminophen-induced hepatic necrosis. 3. Cytochrome P-450-mediated covalent binding in vitro. The Journal of pharmacology and experimental therapeutics, 1973, Volume: 187, Issue:1 Topics: Acetaminophen; Animals; Caffeine; Carbon Monoxide; Carbon Radioisotopes; Chemical and Drug Induced Liver Injury; Cobalt; Cyanides; Cytochrome P-450 Enzyme System; Fluorenes; In Vitro Techniques; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; NADP; Necrosis; Phenobarbital; Piperonyl Butoxide; Protein Binding; Rats; Time Factors; Tritium	1973
Acetaminophen-induced hepatic necrosis. V. Correlation of hepatic necrosis, covalent binding and glutathione depletion in hamsters. Pharmacology, 1974, Volume: 12, Issue:3 Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Cricetinae; Depression, Chemical; Glutathione; Lethal Dose 50; Liver; Male; Methylcholanthrene; Microsomes, Liver; Necrosis; Phenobarbital; Piperonyl Butoxide; Protein Binding; Rats; Stimulation, Chemical	1974
Acetaminophen-induced hepatic necrosis. VI. Metabolic disposition of toxic and nontoxic doses of acetaminophen. Pharmacology, 1974, Volume: 12, Issue:4-5 Topics: Acetaminophen; Acetylcysteine; Animals; Cricetinae; Depression, Chemical; Glutathione; Liver; Mass Spectrometry; Methylcholanthrene; Mice; Necrosis; Phenobarbital; Piperonyl Butoxide; Rats; Species Specificity; Stimulation, Chemical; Tritium	1974
Centrolobular hepatic necrosis related to covalent binding of metabolites of halogenated aromatic hydrocarbons. Experimental and molecular pathology, 1973, Volume: 18, Issue:1 Topics: Animals; Benzene Derivatives; Bromine; Chemical and Drug Induced Liver Injury; Enzyme Induction; Glutathione; Hydrocarbons, Halogenated; Liver; Liver Diseases; Macromolecular Substances; Male; Maleates; Mice; Microsomes, Liver; Necrosis; Nitriles; Phenobarbital; Piperonyl Butoxide; Proadifen; Protein Binding; Pyrazoles; Rats	1973
Metabolism and binding of aromatic hydrocarbons in the lung. Relationship to experimental bronchiolar necrosis. The American review of respiratory disease, 1973, Volume: 107, Issue:4 Topics: Animals; Autoradiography; Bromine; Bronchial Diseases; Carbon Isotopes; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Epithelial Cells; Epithelium; Hydrocarbons, Halogenated; Kidney Diseases; Lung Diseases; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Microsomes; Necrosis; Phenobarbital; Piperonyl Butoxide; Protein Binding; Rats	1973
Acetaminophen-induced hepatic necrosis. I. Role of drug metabolism. The Journal of pharmacology and experimental therapeutics, 1973, Volume: 187, Issue:1 Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Cobalt; Dose-Response Relationship, Drug; Drug Synergism; Kidney; Lethal Dose 50; Liver; Male; Methylcholanthrene; Mice; Mice, Inbred Strains; Necrosis; Phenobarbital; Piperonyl Butoxide; Rats; Species Specificity; Time Factors; Tritium	1973
Acetaminophen-induced hepatic necrosis. II. Role of covalent binding in vivo. The Journal of pharmacology and experimental therapeutics, 1973, Volume: 187, Issue:1 Topics: Acetaminophen; Animals; Carbon Radioisotopes; Cell Nucleus; Chemical and Drug Induced Liver Injury; Cobalt; In Vitro Techniques; Liver; Liver Diseases; Male; Mice; Mice, Inbred Strains; Microsomes, Liver; Mitochondria, Liver; Necrosis; Phenobarbital; Piperonyl Butoxide; Protein Binding; Time Factors; Tritium	1973
Mechanism of renal necrosis induced by bromobenzene or chlorobenzene. Experimental and molecular pathology, 1973, Volume: 19, Issue:2 Topics: Animals; Benzene Derivatives; Carbon Radioisotopes; Chlorobenzenes; Cytochrome P-450 Enzyme System; Histocytochemistry; Hydrocarbons, Brominated; Kidney; Kidney Tubules, Proximal; Liver; Male; Mice; Microsomes, Liver; Necrosis; Phenobarbital; Piperonyl Butoxide; Protein Binding; Proteins; Rats	1973
Chloroform toxicity in mice: correlation of renal and hepatic necrosis with covalent binding of metabolites to tissue macromolecules. Experimental and molecular pathology, 1973, Volume: 19, Issue:2 Topics: Animals; Binding Sites; Carbon Radioisotopes; Chloroform; Cytochrome P-450 Enzyme System; Female; Histocytochemistry; Kidney; Kidney Cortex; Liver; Male; Mice; Microsomes, Liver; Necrosis; Organ Specificity; Phenobarbital; Piperonyl Butoxide; Sex Factors	1973
Inhibition by piperonyl butoxide of phenobarbital mediated induction of mouse liver microsomal enzyme activity. Research communications in chemical pathology and pharmacology, 1974, Volume: 8, Issue:3 Topics: Aminopyrine; Analysis of Variance; Aniline Compounds; Animals; Enzyme Induction; Male; Methyltransferases; Mice; Mice, Inbred ICR; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Piperonyl Butoxide; Time Factors	1974
Biliary excretion of 3-methylcholanthrene as controlled by its metabolism. The Journal of pharmacology and experimental therapeutics, 1972, Volume: 183, Issue:2 Topics: Animals; Benzopyrenes; Bile; Depression, Chemical; Enzyme Induction; Female; Half-Life; Injections, Intravenous; Kinetics; Methylcholanthrene; Metyrapone; Microsomes, Liver; Organ Size; Phenobarbital; Piperonyl Butoxide; Proadifen; Rats; Stimulation, Chemical; Time Factors; Tritium	1972
Bromobenzene metabolism and hepatic necrosis. Pharmacology, 1971, Volume: 6, Issue:1 Topics: Adipose Tissue; Animals; Benzene Derivatives; Bromine; Carbon Isotopes; Chemical and Drug Induced Liver Injury; Chromatography, Gas; Drug Synergism; Liver; Male; Microsomes, Liver; Necrosis; Organ Specificity; Phenobarbital; Piperonyl Butoxide; Proadifen; Rats; Rats, Inbred Strains	1971
Effects of drug-metabolizing enzyme inducers on cephaloridine toxicity in Fischer 344 rats. Toxicology, 1982, Volume: 24, Issue:3-4 Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cephaloridine; Drug Interactions; Enzyme Induction; Kidney; Phenobarbital; Piperonyl Butoxide; Polybrominated Biphenyls; Rabbits; Rats; Rats, Inbred F344; Rats, Inbred Strains; Stilbenes	1982
Effect of rumen development and pre-exposure to chemicals on the activity of the mixed function oxidase system in goats. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1983, Volume: 75, Issue:1 Topics: Aging; Animals; Cytochrome P-450 Enzyme System; Enzyme Induction; Goats; Lung; Microsomes; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital; Piperonyl Butoxide; Rumen	1983
Role of metabolism in the immediate effects and pneumotoxicity of 3-methylindole in goats. British journal of pharmacology, 1984, Volume: 82, Issue:4 Topics: Animals; Biotransformation; Female; Glycerol; Goats; Hemolysis; Indoles; Infusions, Parenteral; Lung Diseases; Male; Mixed Function Oxygenases; Phenobarbital; Piperonyl Butoxide; Skatole	1984
Hepatic and pulmonary microsomal metabolism of naphthalene to glutathione adducts: factors affecting the relative rates of conjugate formation. The Journal of pharmacology and experimental therapeutics, 1984, Volume: 231, Issue:2 Topics: Animals; Cytochrome P-450 Enzyme System; Cytosol; Epoxide Hydrolases; Glutathione; Glutathione Transferase; In Vitro Techniques; Lung; Male; Methylcholanthrene; Mice; Microsomes; Microsomes, Liver; Naphthalenes; Phenobarbital; Piperonyl Butoxide; Proadifen; Proteins	1984
Protective effect of drug metabolism inducer and inhibitor on O,O,S-trimethyl phosphorothioate induced delayed toxicity in rats. Proceedings of the Western Pharmacology Society, 1984, Volume: 27 Topics: Animals; Biotransformation; Drug Interactions; Enzyme Induction; Male; Organothiophosphates; Organothiophosphorus Compounds; Phenobarbital; Piperonyl Butoxide; Proadifen; Rats; Rats, Inbred Strains	1984
Mechanism for isaxonine hepatitis. I. Metabolic activation by mouse and human cytochrome P-450. The Journal of pharmacology and experimental therapeutics, 1984, Volume: 229, Issue:3 Topics: Animals; Biotransformation; Cytochrome P-450 Enzyme System; Humans; Kidney; Kinetics; Male; Mice; Microsomes, Liver; NADP; Oxygen Consumption; Phenobarbital; Piperonyl Butoxide; Pyrimidines	1984
Role of metabolic activation, covalent binding, and glutathione depletion in pulmonary toxicity produced by an impurity of malathion. Toxicology and applied pharmacology, 1984, Mar-15, Volume: 72, Issue:3 Topics: Administration, Oral; Animals; Drug Interactions; Glutathione; Lung; Male; Organothiophosphates; Organothiophosphorus Compounds; Phenobarbital; Piperonyl Butoxide; Rats; Rats, Inbred Strains; Tissue Distribution	1984
Effects of drug and chemical pretreatments on biliary excretion of phenylcyclohexene in the rat. Drug and chemical toxicology, 1984, Volume: 7, Issue:3 Topics: Animals; Bile; Cyclohexanes; Enzyme Induction; Glutathione; Kinetics; Male; Maleates; Methylcholanthrene; Mixed Function Oxygenases; Phenobarbital; Piperonyl Butoxide; Proadifen; Rats; Rats, Inbred Strains; Time Factors	1984
Effect of enzyme inducers and inhibitors and glutathione precursor and depleter on induced acute aflatoxicosis in rabbits. American journal of veterinary research, 1982, Volume: 43, Issue:6 Topics: Acute Disease; Aflatoxin B1; Aflatoxins; Animals; Benzoflavones; Carcinogens; Chlorides; Cobalt; Cysteine; Enzyme Induction; Enzyme Inhibitors; Glutathione; Goats; Liver; Male; Maleates; Microsomes, Liver; Phenobarbital; Phenylbutazone; Piperonyl Butoxide; Rabbits; Rats; Stanozolol	1982
Effect of drug metabolism inducer and inhibitor on O,O,S-trimethyl phosphorothioate-induced delayed toxicity in rats. Chemico-biological interactions, 1983, Jul-01, Volume: 45, Issue:1 Topics: Animals; Body Weight; L-Lactate Dehydrogenase; Lethal Dose 50; Lung; Male; Organothiophosphates; Organothiophosphorus Compounds; Phenobarbital; Piperonyl Butoxide; Proadifen; Rats; Rats, Inbred Strains	1983
Effects of inducers and inhibitors of cytochrome P-450-linked monooxygenases on the toxicity, in vitro metabolism and in vivo irreversible binding of 2-methylnaphthalene in mice. The Journal of pharmacology and experimental therapeutics, 1982, Volume: 221, Issue:3 Topics: Animals; Cytochrome P-450 Enzyme System; Enzyme Induction; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mixed Function Oxygenases; Naphthalenes; Oxidoreductases; Phenobarbital; Piperonyl Butoxide; Proadifen	1982
Toxicologic study of carboxyatractyloside (active principle in cocklebur--Xanthium strumarium) in rats treated with enzyme inducers and inhibitors and glutathione precursor and depletor. American journal of veterinary research, 1982, Volume: 43, Issue:1 Topics: Animals; Atractyloside; Benzoflavones; beta-Naphthoflavone; Cobalt; Cysteine; Glycosides; Kidney Tubules; Lethal Dose 50; Liver; Male; Maleates; Phenobarbital; Phenylbutazone; Piperonyl Butoxide; Plants, Toxic; Rats; Rats, Inbred Strains; Stanozolol	1982
Acetaminophen-induced hypothermia in mice: evidence for a central action of the parent compound. Toxicology, 1982, Volume: 25, Issue:2-3 Topics: Acetaminophen; Animals; Hypothermia; Male; Mice; Phenobarbital; Piperonyl Butoxide; Proadifen; Time Factors; Tissue Distribution	1982
The induction of hepatic cytochrome P-450 in C57 BL/10 and DBA/2 mice by isosafrole and piperonyl butoxide. A comparative study with other inducing agents. Chemico-biological interactions, 1980, Volume: 31, Issue:2 Topics: Animals; Cytochrome P-450 Enzyme System; Dioxoles; Enzyme Induction; Isomerism; Liver; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Microsomes, Liver; Mixed Function Oxygenases; Oxidation-Reduction; Phenobarbital; Piperonyl Butoxide; Pregnenolone Carbonitrile; Safrole	1980
3,5-Dichloroaniline toxicity in Fischer 344 rats pretreated with inhibitors and inducers of cytochrome P450. Toxicology letters, 1995, Volume: 78, Issue:3 Topics: Alanine Transaminase; Analysis of Variance; Aniline Compounds; Animals; Benzoflavones; beta-Naphthoflavone; Blood Urea Nitrogen; Cytochrome P-450 Enzyme System; Enzyme Induction; Enzyme Inhibitors; Injections, Intraperitoneal; Kidney Cortex; Liver; Male; Organ Size; Oxazoles; p-Aminohippuric Acid; Phenobarbital; Piperonyl Butoxide; Pyridines; Rats; Rats, Inbred F344	1995
Protection and potentiation of 1-methyl-4-phenylpyridinium-induced toxicity by cytochrome P450 inhibitors and inducer may be due to the altered uptake of the toxin. Journal of neurochemistry, 1995, Volume: 64, Issue:3 Topics: 1-Methyl-4-phenylpyridinium; Animals; Biological Transport; Brain; In Vitro Techniques; Male; Mice; Monoamine Oxidase Inhibitors; Phenobarbital; Piperazines; Piperonyl Butoxide; Proadifen	1995
Influence of inducers and inhibitors of cytochrome P450 on the hepatotoxicity of hydrazine in vivo. Archives of toxicology, 1994, Volume: 68, Issue:6 Topics: Acetone; Adenosine Triphosphate; Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Glutathione; Hydrazines; Isoniazid; Liver; Male; Phenobarbital; Piperonyl Butoxide; Rats; Rats, Sprague-Dawley; Triglycerides	1994
Effect of microsomal enzyme modulators on N-(3,5-dichlorophenyl)-2-hydroxysuccinimide (NDHS)-induced nephrotoxicity in the Fischer 344 rat. Toxicology, 1993, Nov-12, Volume: 84, Issue:1-3 Topics: Animals; Body Weight; Cobalt; Drug Synergism; Fungicides, Industrial; Injections, Intraperitoneal; Kidney; Male; Microsomes; Organ Size; Phenobarbital; Piperonyl Butoxide; Proteinuria; Rats; Rats, Inbred F344; Succinimides	1993
The effect of the cytochrome P-450 system inducers on the development of Drosophila melanogaster. Journal of biochemical toxicology, 1993, Volume: 8, Issue:2 Topics: Aminophylline; Animals; Cytochrome P-450 Enzyme System; Drosophila melanogaster; Ecdysterone; Enzyme Induction; Female; Hexobarbital; Larva; Mixed Function Oxygenases; Phenobarbital; Piperonyl Butoxide	1993
Increased susceptibility to Bacillus thuringiensis associated with pyrethroid resistance in Bovicola (Damalinia) ovis (Phthiraptera Mallophaga: possible role of monooxygenases. Journal of economic entomology, 1995, Volume: 88, Issue:6 Topics: Animals; Bacillus thuringiensis; Biological Assay; Insecticide Resistance; Insecticides; Lethal Dose 50; Oxygenases; Pesticide Synergists; Phenobarbital; Phthiraptera; Piperonyl Butoxide; Pyrethrins	1995
Cytochrome P450 monooxygenase activity in Haemonchus contortus (Nematoda). International journal for parasitology, 1997, Volume: 27, Issue:1 Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Haemonchus; Kinetics; Larva; Microsomes; Mixed Function Oxygenases; NADP; Phenobarbital; Piperonyl Butoxide; Sheep; Substrate Specificity	1997
Effect of piperonyl butoxide on cell replication and xenobiotic metabolism in the livers of CD-1 mice and F344 rats. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1997, Volume: 38, Issue:1 Topics: Administration, Oral; Animals; Antimetabolites; Body Weight; Bromodeoxyuridine; Cell Division; Cytochrome P-450 Enzyme System; DNA; DNA Replication; Dose-Response Relationship, Drug; Enzyme Induction; GABA Modulators; Liver; Liver Neoplasms; Male; Mice; Microsomes, Liver; Organ Size; Pesticide Synergists; Phenobarbital; Piperonyl Butoxide; Rats; Rats, Inbred F344	1997
Mechanistic study on liver tumor promoting effects of piperonyl butoxide in rats. Archives of toxicology, 1998, Volume: 72, Issue:11 Topics: Animals; Body Weight; Carcinogens; Cell Division; Connexins; Cytochrome P-450 CYP2B1; Eating; Gap Junction beta-1 Protein; Immunochemistry; Intercellular Junctions; Liver; Liver Neoplasms, Experimental; Male; Necrosis; Organ Size; Phenobarbital; Piperonyl Butoxide; Rats; Rats, Inbred F344; Specific Pathogen-Free Organisms	1998
Toxicity of aflatoxin B1 to Helicoverpa zea and bioactivation by cytochrome P450 monooxygenases. Journal of chemical ecology, 2006, Volume: 32, Issue:7 Topics: Aflatoxin B1; Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Activation; Enzyme Inhibitors; Inactivation, Metabolic; Insecticide Resistance; Larva; Lepidoptera; Pesticide Synergists; Phenobarbital; Piperonyl Butoxide; Toxicity Tests	2006
Oxidative DNA damage and reporter gene mutation in the livers of gpt delta rats given non-genotoxic hepatocarcinogens with cytochrome P450-inducible potency. Cancer science, 2010, Volume: 101, Issue:12 Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Carcinogens; Cytochrome P-450 Enzyme System; Deoxyguanosine; DNA Damage; Escherichia coli Proteins; Genes, Reporter; Glutathione Transferase; Immunohistochemistry; Liver; Male; Mutation; Oxidative Stress; Pentosyltransferases; Phenobarbital; Piperonyl Butoxide; Prohibitins; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction	2010
Super-induced gene expression of the N-methyl-D-aspartate receptor 2C subunit in chemical-induced hypertrophic liver in rats. The Journal of toxicological sciences, 2011, Volume: 36, Issue:5 Topics: Animals; Clofibrate; Disease Models, Animal; Gene Expression; Hepatomegaly; Liver; Male; Oligonucleotide Array Sequence Analysis; Organ Size; Phenobarbital; Piperonyl Butoxide; Rats; Rats, Inbred F344; Receptors, N-Methyl-D-Aspartate; Reverse Transcriptase Polymerase Chain Reaction	2011
Estrogen and androgen receptor status in hepatocellular hypertrophy induced by phenobarbital, clofibrate, and piperonyl butoxide in F344 rats. The Journal of toxicological sciences, 2012, Volume: 37, Issue:2 Topics: Animals; Carcinogens; CD36 Antigens; Clofibrate; Estrogen Receptor alpha; Female; Hepatomegaly; Leukemia Inhibitory Factor Receptor alpha Subunit; Liver; Male; Phenobarbital; Piperonyl Butoxide; Rats; Rats, Inbred F344; Receptors, Androgen; RNA, Messenger	2012
Suppressive effect of liver tumor-promoting activities in rats subjected to combined administration of phenobarbital and piperonyl butoxide. The Journal of toxicological sciences, 2013, Volume: 38, Issue:5 Topics: Animals; Carcinoma, Hepatocellular; Cell Proliferation; Cytochrome P-450 CYP1A1; Depression, Chemical; Diethylnitrosamine; Disease Models, Animal; Drug Therapy, Combination; Enzyme Induction; Glutathione S-Transferase pi; Hepatocytes; Liver Neoplasms; Male; Microsomes, Liver; Phenobarbital; Piperonyl Butoxide; Rats; Rats, Inbred F344; Reactive Oxygen Species	2013
Piperonyl butoxide: Mode of action analysis for mouse liver tumour formation and human relevance. Toxicology, 2020, Volume: 439 Topics: Animals; Cell Size; Diet; DNA Replication; Gene Expression Regulation; Hepatocytes; Humans; Liver; Liver Function Tests; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pesticide Synergists; Phenobarbital; Piperonyl Butoxide; Receptors, Calcium-Sensing	2020