piperidines and zinc-chloride

piperidines has been researched along with zinc-chloride* in 2 studies

Other Studies

2 other study(ies) available for piperidines and zinc-chloride

Article	Year
Synthesis of 2-arylpiperidines by palladium couplings of aryl bromides with organozinc species derived from deprotonation of N-boc-piperidine. Organic letters, 2008, Sep-04, Volume: 10, Issue:17 The organolithium species derived from proton abstraction of N-Boc-piperidine with s-BuLi and TMEDA can be transmetalated to the organozinc reagent, and this organometallic species can be coupled directly with aryl bromides in a Negishi-type reaction using palladium catalysis with the ligand tri-tert-butylphosphine (t-Bu3P-HBF4). The chemistry was applied to a very short synthesis of the alkaloid anabasine. Topics: Benzene Derivatives; Chlorides; Formic Acid Esters; Organometallic Compounds; Palladium; Piperidines; Zinc Compounds	2008
Isosteric N-arylpiperazine replacements in a series of dihydropyridine NPY1 receptor antagonists. Bioorganic & medicinal chemistry letters, 2004, Dec-20, Volume: 14, Issue:24 4-Amino-N-arylpiperidines serve as effective bioisosteres for N-arylpiperazines in the series of dihydropyridine NPY1 receptor antagonists. These were prepared by a ZnCl2-mediated reductive amination reaction between elaborated primary amines, 2 or 5, and 4-arylpiperidones. Topics: Biomimetic Materials; Chlorides; Dihydropyridines; Drug Evaluation, Preclinical; Molecular Structure; Piperazines; Piperidines; Receptors, Neuropeptide Y; Structure-Activity Relationship; Zinc Compounds	2004

Article

Year

Synthesis of 2-arylpiperidines by palladium couplings of aryl bromides with organozinc species derived from deprotonation of N-boc-piperidine.

Organic letters, 2008, Sep-04, Volume: 10, Issue:17

The organolithium species derived from proton abstraction of N-Boc-piperidine with s-BuLi and TMEDA can be transmetalated to the organozinc reagent, and this organometallic species can be coupled directly with aryl bromides in a Negishi-type reaction using palladium catalysis with the ligand tri-tert-butylphosphine (t-Bu3P-HBF4). The chemistry was applied to a very short synthesis of the alkaloid anabasine.

Topics: Benzene Derivatives; Chlorides; Formic Acid Esters; Organometallic Compounds; Palladium; Piperidines; Zinc Compounds

2008

Isosteric N-arylpiperazine replacements in a series of dihydropyridine NPY1 receptor antagonists.

Bioorganic & medicinal chemistry letters, 2004, Dec-20, Volume: 14, Issue:24

4-Amino-N-arylpiperidines serve as effective bioisosteres for N-arylpiperazines in the series of dihydropyridine NPY1 receptor antagonists. These were prepared by a ZnCl2-mediated reductive amination reaction between elaborated primary amines, 2 or 5, and 4-arylpiperidones.

Topics: Biomimetic Materials; Chlorides; Dihydropyridines; Drug Evaluation, Preclinical; Molecular Structure; Piperazines; Piperidines; Receptors, Neuropeptide Y; Structure-Activity Relationship; Zinc Compounds

2004