piperidines has been researched along with melamine* in 1 studies
1 other study(ies) available for piperidines and melamine
Article | Year |
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Piperidine-based glycodendrons as protein N-glycan prosthetics.
The generation of homogeneously glycosylated proteins is essential for defining glycoform-specific activity and improving protein-based therapeutics. We present a novel glycodendron prosthetic which can be site-selectively appended to recombinant proteins to create 'N-glycosylated' glycoprotein mimics. Using computational modeling, we designed the dendrimer scaffold and protein attachment point to resemble the native N-glycan architecture. Three piperidine-melamine glycodendrimers were synthesized via a chemoenzymatic route and attached to human growth hormone and the F Topics: Dendrimers; Humans; Molecular Structure; Piperidines; Polysaccharides; Proteins; Triazines | 2016 |