piperidines and libexin

piperidines has been researched along with libexin* in 9 studies

Reviews

1 review(s) available for piperidines and libexin

ArticleYear
Fifteen years of experience on the use of Libexin tablets.
    Therapia Hungarica (English edition), 1989, Volume: 37, Issue:1

    The antitussive Libexin was synthesized in the Research Laboratory of CHINOIN Pharmaceutical and Chemical Works Ltd., Budapest. Observations of the drug in different disease groups have been surveyed on the basis of data published over more than twenty years. According to the unanimous opinion of the authors the drug does not depress respiration, it rather improves the values of the respiratory function. The majority of the examining physicians are on the opinion that it does not hinder expectoration. The drug proved to be of high value in alleviating nocturnal coughing controlling spastic bronchitis in children, as a pretreatment before bronchological examinations and their anaesthesia. It may successfully be used in both acute and chronic bronchitises in preoperative and postoperative cases, in cardiology, otorhinolaryngology and paediatrics.

    Topics: Antitussive Agents; Humans; Hungary; Piperidines; Respiratory Tract Diseases; Tablets

1989

Trials

1 trial(s) available for piperidines and libexin

ArticleYear
[Clinical evaluation of the antitussive action of libexin and baltix].
    Terapevticheskii arkhiv, 1975, Volume: 47, Issue:3

    Topics: Acute Disease; Adult; Aged; Antitussive Agents; Benzhydryl Compounds; Chronic Disease; Clinical Trials as Topic; Codeine; Cough; Dose-Response Relationship, Drug; Drug Evaluation; Female; Humans; Male; Middle Aged; Oxadiazoles; Piperidines; Propanolamines

1975

Other Studies

7 other study(ies) available for piperidines and libexin

ArticleYear
No teratogenic effect of prenoxdiazine: a population-based case-control study.
    Congenital anomalies, 2007, Volume: 47, Issue:1

    The objective of this study was to investigate the human teratogenic potential of oral prenoxdiazine treatment during pregnancy. The analysis of cases with congenital abnormalities and their matched controls without congenital abnormalities was performed in the large population-based data set of the Hungarian Case-Control Surveillance of Congenital Abnormalities, 1980-1996. Of the 22,843 pregnant women who had offspring with congenital abnormalities, 158 (0.7%) were treated with prenoxdiazine. Of the 38,151 pregnant women who had babies without any defects in the study period (control group), 226 (0.6%) were treated with prenoxdiazine (adjusted prevalence odds ratio, 1.0; 95% confidence interval, 0.8-1.3). The comparison of cases and their matched controls did not show a significantly higher rate of prenoxdiazine treatment during the second and third months of gestation in the total (adjusted prevalence odds ratio, 1.4; 95% confidence interval, 0.9-2.2) or in any group of congenital abnormalities. Treatment with prenoxdiazine during pregnancy did not have any teratogenic risk to the fetus. Thus, prenoxdiazine treatment in pregnant women with an unproductive cough may be beneficial.

    Topics: Abnormalities, Drug-Induced; Administration, Oral; Adult; Bacterial Infections; Case-Control Studies; Female; Humans; Hungary; Piperidines; Pregnancy; Pregnancy Complications; Pregnancy Trimester, Second; Pregnancy Trimester, Third

2007
The role of Libexin combination in the symptomatic treatment of different pulmonary diseases.
    Therapia Hungarica (English edition), 1984, Volume: 32, Issue:2

    Topics: Antitussive Agents; Cough; Humans; Lung Diseases; Piperidines

1984
[Studies of the antitussive effect of prenoxdiazine of experimentally induced cough].
    Bratislavske lekarske listy, 1982, Volume: 78, Issue:1

    Topics: Animals; Antitussive Agents; Cats; Cough; Piperidines

1982
[Microdetermination of 3-(2,2-diphenylethyl)-5-(2-piperidine-ethyl)-1,2,4-oxadiazol (Libexin) in biological medium. I. Determination of Libexin by the ion-pair formation method].
    Acta pharmaceutica Hungarica, 1978, Volume: 48, Issue:5

    Topics: Humans; Microchemistry; Oxadiazoles; Piperidines; Polarography

1978
[Microdetermination of Libexin in biological media. II. Fluorometric determination of Libexin].
    Acta pharmaceutica Hungarica, 1978, Volume: 48, Issue:6

    Topics: Fluorometry; Oxadiazoles; Piperidines

1978
Libexin combinatum in the treatment of patients suffering from chronic respiratory tract diseases.
    Therapia Hungarica (English edition), 1978, Volume: 26, Issue:3

    Topics: Adolescent; Adult; Antitussive Agents; Chronic Disease; Female; Humans; Male; Middle Aged; Oxadiazoles; Piperidines; Respiratory Tract Diseases

1978
Effect of libexin combinatum (libexine and emetine) on phagocytosis by polymorphonuclear granulocytes and alveolar macrophages.
    European journal of clinical pharmacology, 1977, Dec-16, Volume: 12, Issue:5

    The ability of human polymorphonuclear granulocytes and alveolar macrophages from rats to ingest Saccharomyces cerevisiae was tested in vitro in the presence of various concentrations of emetine and libexine. Emetine 4.0 and 40.0 microgram/ml caused an increase in the phagocytic index of polymorphonuclear granulocytes and alveolar macrophages. After oral administration of emetine the phagocytosis-enhancing effect was still apparent. Intracellular killing was not influenced by emetine or libexine.

    Topics: Adult; Drug Combinations; Emetine; Female; Humans; In Vitro Techniques; Macrophages; Male; Middle Aged; Neutrophils; Oxadiazoles; Phagocytosis; Piperidines; Pulmonary Alveoli; Saccharomyces cerevisiae

1977