piperidines has been researched along with iodosobenzene* in 2 studies
2 other study(ies) available for piperidines and iodosobenzene
| Article | Year |
|---|---|
Biomimetic oxidation of piperine and piplartine catalyzed by iron(III) and manganese(III) porphyrins.
Synthetic metalloporphyrins, in the presence of monooxygen donors, are known to mimetize various reactions of cytochrome P450 enzymes systems in the oxidation of drugs and natural products. The oxidation of piperine and piplartine by iodosylbenzene using iron(III) and manganese(III) porphyrins yielded mono- and dihydroxylated products, respectively. Piplartine showed to be a more reactive substrate towards the catalysts tested. The structures of the oxidation products were proposed based on electrospray ionization tandem mass spectrometry. Topics: Alkaloids; Benzodioxoles; Biological Products; Biomimetics; Catalysis; Cytochrome P-450 Enzyme System; Ferric Compounds; Inactivation, Metabolic; Iodobenzenes; Iron; Manganese; Oxidation-Reduction; Piperidines; Piperidones; Polyunsaturated Alkamides; Porphyrins; Singlet Oxygen; Spectrometry, Mass, Electrospray Ionization | 2010 |
Oxidation of 3-hydroxypiperidines with iodosylbenzene in water: tandem oxidative Grob fragmentation-cyclization reaction.
Oxidation of 3-hydroxypiperidine with iodosylbenzene in water afforded 2-pyrrolidinone directly in good yields. The reaction probably involves oxidative Grob fragmentation yielding imino aldehyde, which upon hydrolysis produces 2-pyrrolidinone via a cyclization-oxidation sequence. Topics: Cyclization; Iodobenzenes; Molecular Structure; Oxidation-Reduction; Piperidines; Water | 2004 |