piperidines and gramine

piperidines has been researched along with gramine* in 1 studies

Other Studies

1 other study(ies) available for piperidines and gramine

ArticleYear
Substituent effect of N-benzylated gramine derivatives that prevent the PP2A inhibition and dissipate the neuronal Ca
    Bioorganic & medicinal chemistry, 2018, 05-15, Volume: 26, Issue:9

    Following the premises of the multitarget-directed ligands approach for the drug R&D against neurodegenerative diseases, where Alzheimer's disease (AD) outstands, we have synthesized and evaluated analogues of the gramine derivative ITH12657 (1-benzyl-5-methyl-3-(piperidin-1-ylmethyl-1H-indole, 2), which had shown important neuroprotective properties, such as blocking effect of voltage-gated Ca

    Topics: Alkaloids; Alzheimer Disease; Calcium; Calcium Channel Blockers; Cell Line, Tumor; Humans; Indole Alkaloids; Indoles; Molecular Docking Simulation; Molecular Structure; Neurons; Neuroprotective Agents; Okadaic Acid; Piperidines; Protein Phosphatase 2; Structure-Activity Relationship

2018